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Science China(Technological Sciences) 2024年第1期67卷 183-196页

作者： YANG TingTing zhang yuqi YUE FengLai WUNIRI QiQiGe TONG Chao School of Computer Science&Engineering Beihang UniversityBeijing 100191China State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijing 100191China National Innovation Center of Intelligent and Connected Vehicles Beijing 100176China

Time-triggered architecture,as a mainstream design of the distributed real-time system,has been successfully applied in the aerospace,automotive and mechanical ***,time-triggered scheduling is a challenging NP-hard *** are few studies that could quickly solve the scheduling problem of large distributed time-triggered *** solve this problem,a communication affinity parameter is defined in this paper to describe the degree of bias of the shaper task towards sending or receiving *** on this,an innovative task-message decoupling model named D-scheduler is built to reduce the computation complexity of the scheduling problem in large-scale ***,we provide mathematical proof that our model is a convex optimization that is easy to solve with existing computational *** experiments substantiate the efficacy of the *** dramatically reduces the scheduling complexity of large-scale real-time systems with a small loss of solving space compared to the federal scheduler.

关键词： time-triggered architecture time-triggered scheduling communication affinity parameter task-message decoupling model

Dual-aligned porous electrodes for enhanced hydrogen evolution in alkaline water electrolysis

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Nano Research 2024年第5期17卷 3835-3843页

作者： yuqi zhang Wenzhi Cui Longjian Li Chongbo Wang Chen Zhan Xiaojun Quan School of Energy and Power Engineering Chongqing UniversityChongqing 400030China Key Laboratory of Low-grade Energy Utilization Technologies and Systems Chongqing UniversityChongqing 400030China School of Mechanical Engineering Shanghai Jiao-Tong UniversityShanghai 200240China

The efficiency of water electrolysis is significantly affected by the bubbles on the surface and inside the *** enhance the gas-liquid transfer within the porous electrodes,we developed an innovative design termed dual-aligned porous electrode(D-APE),achieved by integrating magnetic alignment with freeze casting *** paper investigates the hydrogen evolution performance of porous electrodes prepared using four different methods:evaporation,magnetic-aligned evaporation,freeze casting,and dual-aligned *** findings demonstrate that the magnetic-aligned process effectively alters the electrode structure,resulting in improved hydrogen evolution ***,among all the examined electrodes,the D-APE exhibits the highest hydrogen evolution performance,with further enhancements observed with prolonged the time of magnetic ***,a comparison is made between electrodes prepared using the freeze casting method and the dual-aligned method at various *** results show that the thinner D-APE exhibits excellent hydrogen evolution performance at high current ***,the D-APE demonstrates significantly improved material utilization rates compared to the conventional freeze casting method,offering promising prospects for enhancing the efficiency of water electrolysis.

关键词： hydrogen evolution reaction dual-aligned magnetic-aligned freeze casting

Functional prediction of tomato PLATZ family members and functional verification of Sl PLATZ17

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Journal of Integrative Agriculture 2024年第1期23卷 141-154页

作者： Min Xu Zhao Gao Dalong Li Chen zhang yuqi zhang Qian He Yingbin Qi He zhang Jingbin Jiang Xiangyang Xu Tingting Zhao College of Horticulture and Landscape Architecture Northeast Agricultural UniversityHarbin 150030China Key Laboratory of Biology and Genetic Improvement of Horticultural Crops(Northeast Region) Ministry of Agriculture and Rural AffairsHarbin 150030China

PLATZ is a novel zinc finger DNA-binding protein that plays an important role in regulating plant growth and development and resisting abiotic ***,there has been very little research on the function of this family gene in tomatoes,which limits its application in germplasm resource ***,the PLATZ gene family was identified and analyzed in tomato,and its roles were predicted and verified to provide a basis for in-depth research on SlPLATZ gene *** this study,the PLATZ family members of tomato were identified in the whole genome,and 19 SlPLATZ genes were *** prediction was conducted based on gene and promoter structure analysis and RNA-seq-based expression pattern *** genes that responded significantly under different abiotic stresses or were significantly differentially expressed among multiple tissues were screened as functional gene ***17 was selected for functional verification by experiment-based *** results showed that the downregulation of SlPLATZ17 gene expression reduced the drought and salt tolerance of tomato *** plants overexpressing SlPLATZ17 had larger flower sizes and long,thin petals,adjacent petals were not connected at the base,and the stamen circumference was *** study contributes to understanding the functions of the SlPLATZ family in tomato and provides a reference for functional gene screening.

关键词： tomato PLATZ family abiotic stresses plant development

Intelligent diagnosis of atrial septal defect in children using echocardiography with deep learning

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虚拟现实与智能硬件（中英文） 2024年第3期6卷 217-225页

作者： Yiman LIU Size HOU Xiaoxiang HAN Tongtong LIANG Menghan HU Xin WANG Wei GU yuqi zhang Qingli LI Jiangang CHEN Shanghai Key Laboratory of Multidimensional Information Processing School of Communication&Electronic EngineeringEast China Normal UniversityShanghaiChina Department of Pediatric Cardiology Shanghai Children's Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Applied Mathematics Xi'an Jiaotong-Liverpool UniversitySchool of ScienceSuzhouChina School of Health Sciences and Engineering University of Shanghai for Science and TechnologyShanghaiChina Minhang District Centers for Disease Control and Prevention ShanghaiChina Faculty of Traditional Chinese Medicine Naval Medical UniversityShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghai 201203China

Background Atrial septal defect(ASD)is one of the most common congenital heart *** diagnosis of ASD via transthoracic echocardiography is subjective and *** The objective of this study was to evaluate the feasibility and accuracy of automatic detection of ASD in children based on color Doppler echocardiographic static images using end-to-end convolutional neural *** proposed depthwise separable convolution model identifies ASDs with static color Doppler images in a standard *** the standard views,we selected two echocardiographic views,i.e.,the subcostal sagittal view of the atrium septum and the low parasternal four-chamber *** developed ASD detection system was validated using a training set consisting of 396 echocardiographic images corresponding to 198 ***,an independent test dataset of 112 images corresponding to 56 cases was used,including 101 cases with ASDs and 153 cases with normal *** The average area under the receiver operating characteristic curve,recall,precision,specificity,F1-score,and accuracy of the proposed ASD detection model were 91.99,80.00,82.22,87.50,79.57,and 83.04,*** The proposed model can accurately and automatically identify ASD,providing a strong foundation for the intelligent diagnosis of congenital heart diseases.

关键词： Deep learning Atrial septal defect Echocardiography

Furin Enzyme-Responsive siRNA Delivery System for Efficient Anti-Hypoxia-Assisted Cancer Photodynamic Therapy

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CCS Chemistry 2024年第4期6卷 999-1010页

作者： Shuyue Ye Yali Feng yuqi zhang Jing Fang Anna Wang Chaoxiang Cui Jinfeng Zhu Liangsheng Guo Guohua Fan Haibin Shi State Key Laboratory of Radiation Medicine and Protection School for Radiological and Interdisciplinary Sciences(RAD-X)and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123 Department of Radiology The Second Affiliated Hospital of Soochow UniversitySuzhou 215004 Department of Obstetrics and Gynecology The Second Affiliated Hospital of Soochow UniversitySuzhou 215004

RNA interfering therapy has emerged as a promising therapeutic modality to treat *** specific and efficient delivery of RNA into a tumor is crucial for achieving effective cancer gene therapy but remains a huge ***,we report a novel furin-responsive small interfering RNA(siRNA)delivery vehicle with multiple functions for colorectal tumor treatment.A peptide-based siRNA delivery vehicle RVRR-P18-Gd,consisting of furin enzyme-specific peptide substrate Arg-Val-Arg-Arg(RVRR)with positive charge for siRNA binding,a Gd(III)chelated 1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetraacetic acid(DOTA)(DOTA-Gd)for magnetic resonance imaging,and purpurin 18 as photosensitizer for photodynamic therapy(PDT),was rationally designed and *** advantage of the cationic amphiphilic feature,RVRR-P18-Gd molecules spontaneously self-assembled with negatively charged Hif-1αsiRNA into stable nanoparticles via attractive electrostatic interaction,which effectively prevented siRNA degradation by nucleases,prolonged the circulation half-life,and enhanced tumor ***,the specific release of Hif-1αsiRNA mediated by endogenous furin significantly downregulated Hif-1αexpression in colorectal cancer cells,resulting in enhanced therapeutic susceptibility,and with the PDT effect,effectively suppressed HCT116 tumor growth in living *** work highlights a powerful and universal approach to precisely deliver siRNA to targeted tumors for efficient synergistic therapy.

关键词： self-assembly RNA interfering enzymeresponsive delivery anti-hypoxia photodynamic therapy

A fluorescence-enhanced inverse opal sensing film for multi-sources detection of formaldehyde

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Food Science and Human Wellness 2024年

作者： Xiaokang Lu Bo Han Deyilei Wei Mingzhu Chu Haojie Ma Ran Li Xueyan Hou yuqi zhang JiJiang Wang Key Laboratory of New Energy & New Functional Materials Shaanxi Key Laboratory of Chemical Reaction Engineering College of Chemistry and Chemical Engineering Yan’an University

The SiO2inverse opal photonic crystals (PC) with a three-dimensional macroporous structure were fabricated by the sacrificial template method， followed by infiltration of a pyrene derivative， 1-(pyren-8-yl)but-3-en-1-amine (PEA)， to achieve a formaldehyde-sensitive and fluorescence-enhanced sensing film. Utilizing the specific Aza-Cope rearrangement reaction of allylamine of PEA and formaldehyde (FA) to generate a strong fluorescent product emitted at ～480 nm， we chose a PC whose blue band edge of stopband overlapped with the fluorescence emission wavelength. In virtue of the fluorescence enhancement property derived from slow photon effect of PC， FA was detected highly selectively and sensitively. The limit of detection (LoD) was calculated to be 1.38 nmol/L. Furthermore， the fast detection of FA (within 1 min) is realized due to the interconnected three-dimensional macroporous structure of the inverse opal PC and its high specific surface area. The prepared sensing film can be used for the detection of FA in air， aquatic products and living cells. The very close FA content in indoor air to the result from FA detector， the recovery rate of 101.5% for detecting FA in aquatic products and fast fluorescence imaging in 2 min for living cells demonstrate the reliability and accuracy of our method in practical applications.

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Practices and Reflections of CNOOC on Building World-Class Enterprises

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China Oil & Gas 2024年第2期31卷 38-51页

作者： Wu Rihan He Xu Li Shuai Yang Xueqin Wei Yujing zhang yuqi CNOOC Energy Economics Institute

At present,China is facing new strategic opportunities as well as risks and challenges in its *** with the challenges brought by current global major risks,China urgently needs to build a group of world-class enterprises as ballast *** the development of a number of world-class enterprises is an important support for China to enhance its comprehensive strength and international competitiveness,and is crucial for the realization of the strategic blueprint for socialist *** more than forty years of reform and opening up,Chinese enterprises have rapidly developed and grown stronger,with their position rising and their influence in the global market increasing ***,Chinese enterprises are“large in size but not yet strong enough”.In this context,this paper systematically analyzes the practical significance and theoretical connotation of building world-class enterprises and the status quo of building world-class enterprises in China and takes CNOOC as an example to deeply analyze the practices of large central enterprises to build world-class enterprises at the levels of group and subsidiaries,providing a reference for Chinese enterprises to accelerate their progress towards world-class enterprises.

关键词： enterprises realization strategic

无源中子符合计数法测量MOX中钚质量铀干扰修正方法研究

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原子能科学技术 2024年第6期58卷 1372-1379页

作者：张俞奇许小明中国原子能科学研究院放射化学研究所北京102413

无源中子符合计数法可以在不破坏MOX(mixed oxide)燃料的前提下,测量其中子信号进行符合分析而得出Pu含量,但在MOX燃料的测量应用过程中,Pu自发裂变中子会诱发U产生显著诱发中子信号,对于Pu的测量产生干扰。通过蒙特卡罗模拟与MSR数据... 详细信息

无源中子符合计数法可以在不破坏MOX(mixed oxide)燃料的前提下,测量其中子信号进行符合分析而得出Pu含量,但在MOX燃料的测量应用过程中,Pu自发裂变中子会诱发U产生显著诱发中子信号,对于Pu的测量产生干扰。通过蒙特卡罗模拟与MSR数据处理方法,开展了无源中子符合计数法测量MOX燃料中Pu质量时U产生的诱发中子信号干扰比例模拟研究。模拟结果分别给出了U诱发信号干扰占比随MOX燃料样品PuO_(2)质量含量、密度、质量的变化关系,得到了明确的函数关系式。该方法适用于样品密度在1.5~9.0 g/cm^(3)、质量在10~500 g、PuO_(2)含量在1%~44%范围的MOX燃料无源中子符合计数法测量的修正,修正因子为0.64%~8.49%,适用于快堆及热堆以及不同生产阶段MOX燃料中U、Pu含量的测量分析。

关键词： MOX 蒙特卡罗模拟无源中子符合计数法

Random forests to predict survival of octogenarians with brain metastases from nonsmall-cell lung cancer

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Brain Science Advances 2024年第1期10卷 39-56页

作者： Lijun Song Yu Wang Xue Li Yi Liu Bingyi Yin Daorui Li Hongsheng Lin yuqi zhang Department of Neurosurgery Yuquan HospitalTsinghua UniversityBeijing 100040China Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Department of Oncology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China

Background:To create and validate nomograms for the personalized prediction of survival in octogenarians with newly diagnosed nonsmall-cell lung cancer(NSCLC)with sole brain metastases(BMs).Methods:Random forests(RF)were applied to identify independent prognostic factors for building nomogram *** predictive accuracy of the model was evaluated based on the receiver operating characteristic(ROC)curve,C-index,and calibration ***:The area under the curve(AUC)values for overall survival at 6,12,and 18 months in the validation cohort were 0.837,0.867,and 0.849,respectively;the AUC values for cancer-specific survival prediction were 0.819,0.835,and 0.818,*** calibration curves visualized the accuracy of the ***:The new nomograms have good predictive power for survival among octogenarians with sole BMs related to NSCLC.

关键词： octogenarian NSCLC brain metastases random forests nomogram

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双轴承旋转喷管型面设计及数值模拟研究

推进技术 2024年第5期45卷 95-106页

作者：李瑶徐惊雷潘睿丰张玉琪黄帅南京航空航天大学航空航天结构力学及控制全国重点实验室江苏南京210016 南京航空航天大学能源与动力学院江苏南京210016

针对短距/垂直起降战斗机高机动飞行的迫切需求及其矢量喷管机械结构复杂笨重的问题,提出了基于轴对称双喉道气动矢量喷管设计的双轴承旋转喷管,通过采用双轴承结构和双喉道气动矢量喷管相结合的方式,减少驱动结构,使喷管能更高效、轻... 详细信息

针对短距/垂直起降战斗机高机动飞行的迫切需求及其矢量喷管机械结构复杂笨重的问题,提出了基于轴对称双喉道气动矢量喷管设计的双轴承旋转喷管,通过采用双轴承结构和双喉道气动矢量喷管相结合的方式,减少驱动结构,使喷管能更高效、轻便地实现短距/垂直起降,并且赋予了飞行器平飞模态高机动飞行的潜力。基于典型轴对称双喉道气动矢量喷管构型,开展了双轴承旋转喷管的型面设计和运动规律研究,利用数值模拟开展关键设计参数对喷管流场的影响研究,获得喷管的性能变化规律。结果表明,短距/垂直起降模态下,典型构型的双轴承旋转喷管推力矢量角最大可达108°,满足短距/垂直起降飞行器对喷管的要求。凹腔段的长短轴比值对喷管短距/垂直起降模态的性能影响较大,相同落压比条件下,长短轴比值越大,喷管的总推力系数越低,推力矢量角越大,并且推力矢量角最大差值达到41°。本文所提出的双轴承旋转喷管可为未来具备短距/垂直起降、高机动性能的飞行器动力系统提供一种新的解决方案。

关键词：短距/垂直起降双轴承旋转喷管双喉道气动矢量喷管气动性能数值模拟

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