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Cooperative Jobs Dispatching in Edge Computing Network with Unpredictable Uploading Delay

Journal of Communications and Information Networks 2020年第1期5卷 75-85页

作者： Bojie Lyu yuncong hong Haisheng Tan Zhenhua Han Rui Wang Department of Electrical and Electronic Engineering Southern University of Science and Technology(SUSTech)Shenzhen 518055China Department of Electrical and Electronic Engineering Southern University of Science and Technology(SUSTech)Shenzhen 518055China Department of Computer Sciencethe University of Hong Kong(HKU)Hong Kong 999077China LINKE Lab University of Science and Technology of China(USTC)Hefei 230026China

In this paper,the cooperative jobs dispatching problem in an edge computing network with multiple access points(APs)and edge servers is *** to the uncertain traffic in the network between APs and edge servers,the job uploading delay can not be predicted ***,the job arrivals at the APs,the job uploading delay from APs to edge servers and the job computation time at the edge servers are all modeled as random *** each job dispatching decision will affect the system state in the future,we formulate the joint optimization of jobs dispatching at all the APs and all the scheduling time slots as an infinite-horizon Markov decision process(MDP).The minimization objective is a discounted measurement of the average processing time per job,including the uploading delay,the waiting time and the computation time at the edge *** this problem,the approximate MDP should be adopted to address the curse of *** low-complexity approximate solution of MDP is usually hard to predict the performance *** this paper,a novel approximate MDP solution framework is proposed via one-step policy iteration over a baseline policy,where the analytical performance bound can be ***,since the expression of the approximate value function is derived,the value iteration in conventional methods can be eliminated,which can essentially reduce the computation *** is shown by simulations that the proposed low-complexity algorithm has significantly better performance than various benchmark schemes.

关键词： edgecomputing Markovdecisionprocess(MDP) approximateMDP jobsdispatching

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Effect of plateletcrit and methylenetetrahydrofolate reductase(MTHFR)C677T genotypes on folic acid efficacy in stroke prevention

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2694-2701页

作者： yuncong Shi Zhengzhipeng Zhang Binyan Wang Yu Wang Xiangyi Kong Yong Sun Aimin Li Yimin Cui Yan Zhang Jianping Li Yong Huo Hui Huang Cardiovascular Department The Eighth Affiliated HospitalJoint Laboratory of Guangdong-Hong Kong-Macao Universities for Nutritional Metabolism and Precise Prevention and Control of Major Chronic DiseasesSun Yat-sen UniversityShenzhenChina Shenzhen Evergreen Medical Institute ShenzhenChina Shenzhen Tailored Medical Laboratory ShenzhenChina Department of Cardiology Beijing Anzhen HospitalCapital Medical UniversityBeijingChina Department of Neurosurgery The First Affiliated Hospital of Kangda College of Nanjing Medical UniversityLianyungangChina Institute of Clinical Pharmacology Peking University First HospitalBeijingChina Department of Cardiology Peking University First HospitalBeijingChina

Previous studies have shown that low platelet count combined with high plasma total homocysteine(tHcy)increased stroke risk and can be lowered by 73% with folic ***,the combined role of other platelet activation parameters and the methylenetetrahydrofolate reductase(MTHFR)C677T genotypes on stroke risk and folic acid treatment benefit remain to be *** study aimed to investigate if platelet activation parameters and MTHFR genotypes jointly impact folic acid treatment efficacy in first stroke *** were derived from the China Stroke Primary Prevention *** study includes a total of 11,185 adult hypertensive patients with relevant platelet activation parameters and MTHFR genotype *** simultaneously considering both platelet activation parameters(plateletcrit,platelet count,mean platelet volume,platelet distribution width)and MTHFR genotypes,patients with both low plateletcrit(Q1)and the TT genotype had the highest stroke incidence rate(5.6%)in the enalapril *** subgroup significantly benefited from folic acid treatment,with a 66% reduction in first stroke(HR:0.34;95%CI:0.14-0.82;p=0.016).Consistently,the subgroup with low plateletcrit(Q1)and the CC/CT genotype also benefited from folic acid treatment(HR:0.40;95%CI:0.23-0.70;p=0.001).In Chinese hypertensive adults,low plateletcrit can identify those who may greatly benefit from folic acid treatment,in particular,those with the TT genotype,a subpopulation known to have the highest stroke risk.

关键词： prevention treatment MTHFR

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Polarity-triggered anti-Kasha system for high-contrast cell imaging and classification

聚集体(英文)

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聚集体(英文) 2023年第2期4卷 216-226页

作者： Junyi Gong Peifa Wei Junkai Liu yuncong Chen Zheng Zhao Weijun Zhao Huilin Xie Chao Ma Jacky W.Y.Lam Kam Sing Wong Ying Li Ben Zhong Tang Shenzhen Institute of Aggregate Science and Technology School of Science and EngineeringThe Chinese University of Hong KongShenzhenChina Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and ReconstructionInstitute for Advanced StudyState Key Laboratory of Molecular NanoscienceDivision of Life Science and Department of Chemical and Biological EngineeringThe Hong Kong University of Science and TechnologyClear Water BayKowloonChina Institutes of Physical Science and Information Technology Anhui UniversityHefeiChina Department of Physics HKUSTKowloonChina Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology The NMPA and State Key Laboratory of Respiratory DiseaseInnovation Research Center for AIE Pharmaceutical BiologySchool of Pharmaceutical Sciences and the Fifth Affiliated HospitalGuangzhou Medical UniversityGuangzhouChina Center for AIE Research Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Material Science and EngineeringShenzhen UniversityShenzhenChina Center for Aggregation-Induced Emission SCUT-HKUST Joint Research InstituteState Key Laboratory of Luminescent Materials and DevicesSouth China University of TechnologyGuangzhouChina AIE Institute Guangzhou Development DistrictHuangpuChina

Kasha’s rule,which states that all exciton emissions occur from the lowest excited state and are independent of excitation energy,makes high-energy excitons difficult to use and severely hinders the widespread applications of organic photoluminescent materials in the real *** decades,scientists have tried to break this rule to unleash the power of high-energy excitons,but only minimal progress has been achieved,with no rational guiding principles provided,and few applications *** far,breaking Kasha’s rule has remained a purely academic *** this paper,we introduce a design principle for a purely organic anti-Kasha system and synthesise a series of compounds based on the design *** predicted,these compounds all display evident S_(2) emissions in dilute *** addition,we introduce a highly accurate(over 90%)convolutional neural network as an assistant for the classification of cells using anti-Kasha luminogens,thereby providing a new application direction for anti-Kasha systems.

关键词： anti-Kasha cell classification excited-state dynamics fluorescence

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McMYB4 improves temperature adaptation by regulating phenylpropanoid metabolism and hormone signaling in apple

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Horticulture Research 2021年第1期8卷 2319-2332页

作者： Suxiao Hao Yanfen Lu Zhen Peng Enying Wang Linke Chao Silin Zhong yuncong Yao Beijing Advanced Innovation Center for Tree Breeding by Molecular Design Beijing University of AgricultureBeijing 102206China Beijing Bei Nong Enterprise Management Co.Ltd Beijing 102206China Plant Science and Technology College Beijing University of AgricultureBeijing 102206China Beijing Key Laboratory for Agricultural Application and New Technique Beijing University of AgricultureBeijing 102206China College of Forestry Beijing Forestry UniversityBeijing 100083China College of Life Science The Chinese University of Hong KongHong KongChina

Temperature changes affect apple development and *** metabolism and hormone signaling play a crucial role in regulating apple growth and development in response to temperature ***,we found that McMYB4 is induced by treatment at 28℃ and 18℃,and McMYB4 overexpression results in flavonol and lignin accumulation in apple *** one-hybrid(Y1H)assays and electrophoretic mobility shift assays(EMSAs)further revealed that McMYB4 targets the promoters of the flavonol biosynthesis genes CHS and FLS and the lignin biosynthesis genes CAD and ***4 expression resulted in higher levels of flavonol and lignin biosynthesis in apple during growth at 28℃ and 18℃ than during growth at 23℃.At 28℃ and 18℃,McMYB4 also binds to the AUX/ARF and BRI/BIN promoters to activate gene expression,resulting in acceleration of the auxin and brassinolide signaling *** together,our results demonstrate that McMYB4 promotes flavonol biosynthesis and brassinolide signaling,which decreases ROS contents to improve plant resistance and promotes lignin biosynthesis and auxin signaling to regulate plant *** study suggests that McMYB4 participates in the abiotic resistance and growth of apple in response to temperature changes by regulating phenylpropanoid metabolism and hormone signaling.

关键词： phenyl acceleration metabolism

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迷迭香提取物稳定性研究

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食品科技 2021年第11期46卷 224-228页

作者：王金香李云聪田洪牛志平晨光生物科技集团股份有限公司河北邯郸057250

研究光照、水分、氧气、温度因素对不同规格迷迭香提取物稳定性的影响。结果显示:脂溶性迷迭香提取物稳定性较好,对光照、氧气、水分因素均不敏感;不同规格脂溶性迷迭香提取物热稳定性差异较大,鼠尾草酸油剂、高含量鼠尾草酸粉末热稳定... 详细信息

研究光照、水分、氧气、温度因素对不同规格迷迭香提取物稳定性的影响。结果显示:脂溶性迷迭香提取物稳定性较好,对光照、氧气、水分因素均不敏感;不同规格脂溶性迷迭香提取物热稳定性差异较大,鼠尾草酸油剂、高含量鼠尾草酸粉末热稳定性较好,低含量鼠尾草酸粉末则热稳定性较差,105 ℃放置12 h条件下,鼠尾草酸油剂、低含量鼠尾草酸粉末、高含量鼠尾草酸粉末保存率分别为91.87%、52.44%、83.76%;水溶性迷迭香提取物对光照、氧气因素不敏感,热稳定性较好,但吸湿性较强,吸湿后纯度降低。

关键词：迷迭香提取物鼠尾草酸迷迭香酸稳定性

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Combinatorial cell surface display system in Escherichia coli for noninvasive colorectal cancer detection

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Journal of Bio-X Research 2019年第4期2卷 185-196页

作者： Hsiao Chiayi Fang Qingwei Zheng Shuyu He Peixiang Zhang Kairan hong Yirui Ran yuncong Sun Shiyu Liu Zhixiang Liang Zhihan Zhong Bozitao Wu Weiwen Xia Ruoyu Bai Shihao Yao Kuan Wang Yushu He Lin Ma Gang Bio-X-Renji Hospital Research Center Renji HospitalSchool of MedicineShanghaiChina Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders(Ministry of Education)ShanghaiChina 2018 SJTU-BioX-Shanghai Team for The International Genetically Engineered Machine Competition(iGEM) Shanghai Jiao Tong UniversityShanghaiChina Shanghai Jiao Tong University School of MedicineShanghaiChina

Navigation and recognition of disease lesions remain challenging during colorectal cancer diagnosis and treatment,given that the precision and capacity of using specific surface antigens as recognition sites are relatively ***,the low penetration rate of noninvasive detection methods has delayed disease diagnosis in developing *** developed a bacterial device targeting the Thomsen-Friedenreich antigen,which is abundant on lesion tissue,and produced vesicles that serve as markers for ultrasonic *** device uses a bacterial cell surface display system and acoustic reporter gene to function as a screening device for colorectal cancer *** diagnostic efficiency of this device was determined by flow cytometry,immunohistochemistry,microfluidic chip-based assay,and ultrasonic examinations on both cellular and tissue *** all scales and experiments,our device showed great feasibility upon differentiating disease lesion and normal tissue,while foundation of the usage of vesicle reporter system as noninvasive method has also been *** application of this device provides insight into the practicability and prospect of bacterial detecting agents in the field of *** animal studies were approved by the Institutional Animal Care and Use Committee of Shanghai Jiao Tong University,China(approval No.201801015)on February 23,2018.

关键词： colorectal cancer cell-surface display ice nucleation protein ultrasonic detection

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上海市发热哨点诊室与新加坡公共卫生防范诊所模式对比研究

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中国全科医学 2021年第34期24卷 4306-4311页

作者：朱晓燕杨永华黄贇聪朱敏黄倩周良石建伟王朝昕梁鸿黄蛟灵上海交通大学医学院公共卫生学院上海市200025 上海市虹口区北外滩街道社区卫生服务中心 200082 上海市浦东新区潍坊社区卫生服务中心 200122 复旦大学社会发展与公共政策学院上海市200433

背景上海市在我国率先提出建设社区卫生服务中心发热哨点诊室,发热哨点诊室在防疫体系中承担着"网底"功能。公共卫生防范诊所(PHPC)是新加坡成熟的公共卫生体系中的一个分支系统。目的对比上海市发热哨点诊室与新加坡PHPC模式,探究双方... 详细信息

背景上海市在我国率先提出建设社区卫生服务中心发热哨点诊室,发热哨点诊室在防疫体系中承担着"网底"功能。公共卫生防范诊所(PHPC)是新加坡成熟的公共卫生体系中的一个分支系统。目的对比上海市发热哨点诊室与新加坡PHPC模式,探究双方在基层疫情防控方面的差异,并对完善上海市发热哨点诊室建设提出建议。方法于2020年12月至2021年4月,选取上海市中心城区、远郊、城郊结合区各一家社区卫生服务中心发热哨点诊室作为样本机构,通过对发热哨点诊室管理人员和医务人员开展两轮访谈,以及对样本机构开展现场调研,并辅以文献检索,获取上海市发热哨点诊室模式及应用资料。通过检索新加坡卫生部官网和数据库文献,获得新加坡PHPC模式及其应用资料。结果新加坡PHPC模式诊所数量、密度高于上海市发热哨点诊室;上海市发热哨点诊室的设置标准要求高,但新加坡PHPC的准入"门槛"更高;上海市发热哨点诊室在就诊流程方面更具个性化;新加坡PHPC模式对防疫补贴、医护人员保障方面较为突出。结论新加坡PHPC模式具有更长的筹建时间,由政府自上而下制定标准、准入批准、统筹布局,呈现出更高的同质性与缜密性,上海市发热哨点的建设起步较晚,呈现出更高的个性化与本土化特征。

关键词：哨点监测发热诊室社区卫生服务新型冠状病毒肺炎新加坡上海

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萧云从绘画艺术风格形成原因探究

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安徽工业大学学报（社会科学版） 2022年第3期39卷 28-30页

作者：祝虹马鞍山师范高等专科学校教师教育系安徽马鞍山243041

萧云从的绘画,笔力坚挺,刚劲有力,古朴俊秀,清流韶华,笔墨爽利,笔笔有神,环境、意境、心境、画境结合,情感与灵性融合,生机与活力统一。这种绘画艺术风格的形成,在于他对徽州版画的借鉴,对宋元代山水画的创新,对爱国情感的抒发,对家乡... 详细信息

萧云从的绘画,笔力坚挺,刚劲有力,古朴俊秀,清流韶华,笔墨爽利,笔笔有神,环境、意境、心境、画境结合,情感与灵性融合,生机与活力统一。这种绘画艺术风格的形成,在于他对徽州版画的借鉴,对宋元代山水画的创新,对爱国情感的抒发,对家乡山水的热爱和对传统文化的领悟。

关键词：萧云从绘画艺术风格成因

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屈原诗歌图绘传播的计量分析

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湖北第二师范学院学报 2015年第1期32卷 1-6,37页

作者：龚红林湖北第二师范学院文学院湖北方言文化研究中心武汉430205

屈原诗歌的图绘传播,特指取材于屈原诗作用美术绘画形式将屈诗中丰富的题材、情感、想象、文辞等加以展示的传播方式。通过统计分析历代画谱类、笔记类书籍及当代楚辞书目中所著录的屈原诗歌图绘,可知,屈原诗歌的图绘传播始于南朝宋(420... 详细信息

屈原诗歌的图绘传播,特指取材于屈原诗作用美术绘画形式将屈诗中丰富的题材、情感、想象、文辞等加以展示的传播方式。通过统计分析历代画谱类、笔记类书籍及当代楚辞书目中所著录的屈原诗歌图绘,可知,屈原诗歌的图绘传播始于南朝宋(420-479),绘图作者总数突增出现在明代;历代图绘最多的是屈原的《九歌》;历代传播最广的是北宋李公麟《九歌图》,其次是明末萧云从绘、清门应兆补绘《离骚全图》。图绘屈原诗歌,实质是变通取意的图像阐释模式,对普通读者和观画者具有比文字更强的视觉冲击力,对观画者精神起了提升浸润作用。

关键词：屈原诗歌图绘传播计量分析

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萧云从艺术精神浅析

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安徽工业大学学报（社会科学版） 2018年第1期35卷 67-68,92页

作者：祝虹潘杨马鞍山师范高等专科学校教师教育系安徽马鞍山243041

萧云从是姑孰画派的领袖人物,创造性地将生命意识注入地缘山水的诠释和艺术表达之中,拓宽了古典文人绘画的视野,为徽皖诸派提携引路,还间接促成扶桑南宗绘事繁荣,在殊方异域声名远播,对中国乃至世界绘画影响深远。

关键词：萧云从姑孰画派艺术精神

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