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Improved Diurnal Cycle of Precipitation on Land in a Global Non-Hydrostatic Model Using a Revised NSAS Deep Convective Scheme

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Advances in Atmospheric Sciences 2024年第6期41卷 1217-1234页

作者： Yifan ZHAO Xindong peng Xiaohan li Siyuan CHEN State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China University of Chinese Academy of Sciences Beijing 100049China CMA Earth System modeling and Prediction Centre Beijing 100081China 2035 Future Laboratory PIESAT Information Technology Co Ltd.Beijing 100195China

In relatively coarse-resolution atmospheric models,cumulus parameterization helps account for the effect of subgridscale convection,which produces supplemental rainfall to the grid-scale precipitation and impacts the diurnal cycle of *** this study,the diurnal cycle of precipitation was studied using the new simplified Arakawa-Schubert scheme in a global non-hydrostatic atmospheric model,i.e.,the Yin-Yang-grid Unified Model for the *** new diagnostic closures and a convective trigger function were suggested to emphasize the job of the cloud work function corresponding to the free tropospheric large-scale *** results of the 0.25-degree model in 3-month batched real-case simulations revealed an improvement in the diurnal precipitation variation by using a revised trigger function with an enhanced dynamical constraint on the convective initiation and a suitable threshold of the *** reducing the occurrence of convection during peak solar radiation hours,the revised scheme was shown to be effective in delaying the appearance of early-afternoon rainfall peaks over most land areas and accentuating the nocturnal peaks that were wrongly concealed by the more substantial afternoon *** addition,the revised scheme enhanced the simulation capability of the precipitation probability density function,such as increasing the extremely low-and high-intensity precipitation events and decreasing small and moderate rainfall events,which contributed to the reduction of precipitation bias over mid-latitude and tropical land areas.

关键词： cumulus parameterization diurnal cycle of precipitation large-scale dynamic forcing global non-hydrostatic atmospheric model performance verification

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Afterglow Nanoprobes for In-vitro Background-free Biomarker Analysis

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Chemical Research in Chinese Universities 2024年第2期40卷 213-224页

作者： ZHENG Ting WANG Ying li Xianming li Chenghui WU peng Analytical&Testing Centre State Key Laboratory of Hydraulics and Mountain River EngineeringSichuan UniversityChengdu610064P.R.China School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang453007P.R.China Department of Rheumatology and Immunology West China HospitalSichuan UniversityChengdu610064P.R.China

Accurate detection of biomarkers is essential for disease *** the highly sensitive fluorescence probes are feasible for the above goal,it is typically interfered by the auto-fluorescence and light scattering of the biological *** afterglow system(consisting of photosensitizer,afterglow substrate and emitter)based on cascade photochemical reactions exhibits long-lived luminescence(seconds to hours),thus avoiding background *** the assistance of polymers,such as polystyrene microspheres,the photochemical afterglow systems have been transformed into homogeneous and water-soluble nanoparticles,and used for in-vitro biomarker ***,we summarized the principle,preparation and applications of these afterglow nanoparticles,and evaluated their performance in clinical sample testing by comparing with other nanoparticle-based ***,several problems and possible solutions of afterglow nanoparticle-based methods in biomarker determination were also mentioned.

关键词： Photochemical afterglow In-vitro analysis Background-free detection Biomarker

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Existence of Positive Solutions to a Fractional-Kirchhoff System

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 225-240页

作者： peng-fei li Jun-hui Xie Dan Mu School of Mathematics and Statistics Hubei Minzu UniversityEnshi445000China

LetΩbe a bounded smooth domain in RN(N≥3).Assuming that 00 are constants,we consider the existence results for positive solutions of a class of fractional elliptic system below,{(a+b[u]^(2)_(s))(-Δ)^(s)u=vp+h_(1)(x,u,v,▽u,▽v),x∈Ω,(-Δ)^(s)v=u^(q)+h_(2)(x,u,▽,▽u,▽v),x∈Q,u,v>0,x∈Ω,u=v=0,x∈RN\Ω.Under some assumptions of hi(x,u,v,▽u,▽v)(i=1,2),we get a priori bounds of the positive solutions to the problem(1.1)by the blow-up methods and rescaling *** on these estimates and degree theory,we establish the existence of positive solutions to problem(1.1).

关键词： fractional-Kirchhoff system a priori bounds degree theory positive solution

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A Survey on the Evolution of Bootkits Attack and Defense Techniques

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China Communications 2024年第1期21卷 102-130页

作者： Yilin Zhou Guojun peng Zichuan li Side liu Key Laboratory of Aerospace Information Security and Trust Computing Ministry of EducationWuhan 430072China School of Cyber Science and Engineering Wuhan UniversityWuhan 430072China

According to the boot process of modern computer systems,whoever boots first will gain control *** advantage of this feature,a malicious code called bootkit can hijack the control before the OS bootloader and bypass security mechanisms in boot *** makes bootkits difficult to detect or clean up *** the improvement of security mechanisms and the emergence of UEFI,the attack and defense techniques for bootkits have constantly been *** first introduce two boot modes of modern computer systems and present an attack model of bootkits by some sophistical *** we discuss some classic attack techniques used by bootkits from their initial appearance to the present on two axes,including boot mode axis and attack phase ***,we evaluate the race to the bottom of the system and the evolution process between bootkits and security *** last,we present the possible future direction for bootkits in the context of continuous improvement of OS and firmware security mechanisms.

关键词： bootkit hook legacy BIOS security mechanisms UEFI

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Spacelike Framed Curves with lightlike Components and Singularities of Their Evolutes and Focal Surfaces in Minkowski 3-space

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1521-1532页

作者： peng Cheng li Dong He PEI Xin ZHAO School of Mathematics and Statistics Northeast Normal UniversityChangchun 130024P.R.China Department of Mathematics Harbin Institute of TechnologyWeihai 264209P.R.China School of Mathematics and Statistics Qingdao UniversityQingdao 266071P.R.China

In this paper,we define the evolute and focal surface of a spacelike framed curve with lightlike components in Minkowski *** is a generalization of the previous results of regular spacelike curves,since singularities are allowed in the original spacelike curves studied by spacelike framed curves with lightlike ***,we show a new geometric invariant to characterise singularities of the focal ***,the classification theorem and recognition theorem for the singularities of the focal surface in generic are also given.

关键词： Evolutes focal surfaces spacelike framed curves singularities

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Understanding the Relationship Between Shrinking Cities and Land Prices:Spatial Pattern,Effectiveness,and Policy Implications

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Chinese Geographical Science 2024年第1期34卷 1-18页

作者： WANG Xiaohui peng li HUANG Kexin DENG Wei College of Geography and Resources Sichuan Normal UniversityChengdu610101China Key Laboratory of Land Resources Evaluation and Monitoring in Southwest Ministry of EducationSichuan Normal UniversityChengdu610101China

Urban shrinkage has emerged as a widespread phenomenon globally and has a significant impact on land,particularly in terms of land use and *** study focuses on 2851 county-level cities in China in 2005–2018(excluding Hong Kong,Macao,Taiwan,and‘no data’areas in Qinhai-Tibet Plateau)as the fundamental units of *** employing nighttime light(NTL)data to identify shrinking cities,the propensity score matching(PSM)model was used to quantitatively examine the impact of shrinking cities on land prices,and evaluate the magnitude of this *** findings demonstrate the following:1)there were 613 shrinking cities in China,with moderate shrinkage being the most prevalent and severe shrinkage being the least.2)Regional disparities are evident in the spatial distribution of shrinking cities,especially in areas with diverse terrain.3)The spatial pattern of land price exhibits a significant correlated to the economic and administrative levels.4)Shrinking cities significantly negatively impact on the overall land price(ATT=–0.1241,P<0.05).However,the extent of the effect varies significantly among different spatial *** study contributes novel insights into the investigation of land prices and shrinking cities,ultimately serving as a foundation for government efforts to promote the sustainable development of urban areas.

关键词： shrinking cities land price propensity score matching(PSM) relative effectiveness China

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Anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab for first-line treatment in advanced natural killer T cell lymphoma

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1665-1674页

作者： Jie Xiong Shu Cheng Xiao Gao Shan-He Yu Yu-Ting Dai Xin-yun Huang Hui-Juan Zhong Chao-Fu Wang Hong-Mei Yi Hao Zhang Wei-Guo Cao Rong li Wei Tang Yan Zhao peng-peng Xu li Wang Wei-li Zhao Shanghai Institute of Hematology State Key Laboratory of Medical GenomicsNational Research Center for Translational Medicine at ShanghaiRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Nuclear Medicine Shanghai Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Pathology Shanghai Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Otolaryngology Shanghai Rujin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Radiation Shanghai Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Hematology Navy Medical Center of PLAShanghaiChina Pole de Recherches Sino-Francais en Science du Vivant et Genomique Laboratory of Molecular PathologyShanghaiChina

Natural killer T cell lymphoma(NKTCL)is highly aggressive,with advanced stage patients poorly responding to intensive *** explore effective and safe treatment for newly diagnosed advanced stage NKTCL,we conducted a phase ll study of anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab(NCT04096690).Twenty-two patients with a median age of 51 years(range,24-74)were enrolled and treated with induction treatment of pegaspargase 2500 IU/m2 intramuscularly on day 1 and sintilimab 200 mg intravenously on day 2 for 6 cycles of 21 days,followed by maintenance treatment of sintilimab 200 mg for 28 cycles of 21 *** complete response and overall response rate after induction treatment were 59%(95%Cl,43-79%)and 68%(95%Cl,47-84%),*** a median follow-up of 30 months,the 2 year progression-free and overall survival rates were 68%(95%Cl,45-83%)and 86%(95%Cl,63-95%),*** most frequently grade 3/4 adverse events were neutropenia(32%,n=7)and hypofibrinogenemia(18%,n=4),which were manageable and led to no discontinuation of *** proportion score of PD-L1,peripheral blood high-density lipoprotein cholesterol,and apolipoprotein A-l correlated with good response,while PD-1 on tumor infiltrating lymphocytes and peripheral Treg cells with poor response to pegaspargase plus sintilimab *** conclusion,the chemo-free regimen pegaspargase plus sintilimab was effective and safe in newly diagnosed,advanced stage *** lipid profle and immunosuppressive signature contributed to treatment resistance,providing an alternative therapeutic approach dual targeting fatty acid metabolism and CTLA-4 in NKTCL.

关键词： killer metabolism lymphoma

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Reconstructing historical forest fire risk in the non-satellite era using the improved forest fire danger index and long short-term memory deep learning-a case study in Sichuan Province,southwestern China

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Forest Ecosystems 2024年第1期11卷 87-99页

作者： Yuwen peng Huiyi Su Min Sun Mingshi li Co-Innovation Center for Sustainable Forestry in Southern China Nanjing Forestry UniversityNanjing 210037China College of Forestry Nanjing Forestry UniversityNanjing 210037China

Historical forest fire risk databases are vital for evaluating the effectiveness of past forest management approaches,enhancing forest fire warnings and emergency response capabilities,and accurately budgeting potential carbon emissions resulting from ***,due to the unavailability of spatial information technology,such databases are extremely difficult to build reliably and completely in the non-satellite *** study presented an improved forest fire risk reconstruction framework that integrates a deep learning-based time series prediction model and spatial interpolation to address the challenge in Sichuan Province,southwestern ***,the forest fire danger index(FFDI)was improved by supplementing slope and aspect *** compared the performances of three time series models,namely,the autoregressive integrated moving average(ARIMA),Prophet and long short-term memory(LSTM)in predicting the modified forest fire danger index(MFFDI).The bestperforming model was used to retrace the MFFDI of individual stations from 1941 to *** this,the Anusplin spatial interpolation method was used to map the distributions of the MFFDI at five-year intervals,which were then subjected to weighted overlay with the distance-to-river layer to generate forest fire risk maps for reconstructing the forest fire danger *** results revealed LSTM as the most accurate in fitting and predicting the historical MFFDI,with a fitting determination coefficient(R^2)of 0.709,mean square error(MSE)of0.047,and validation R^2 and MSE of 0.508 and 0.11,*** validation of the predicted forest fire risk maps indicated that 5 out of 7 historical forest fire events were located in forest fire-prone areas,which is higher than the results determined from the original FFDI(2 out of 7).This proves the effectiveness of the improved MFFDI and indicates a high level of reliability of the historical forest fire risk reconstruction method proposed in this stu

关键词： Forest fire risk reconstruction MFFDI Time series models LSTM ARIMA Prophet Anusplin

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Representation learning: serial-autoencoder for personalized recommendation

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Frontiers of Computer Science 2024年第4期18卷 61-72页

作者： Yi ZHU Yishuai GENG yun li Jipeng QIANG Xindong WU School of Information Engineering Yangzhou UniversityYangzhou 225127China Key Laboratory of Knowledge Engineering with Big Data(Ministry of Education of the People’s Republic of China) Hefei University of TechnologyHefei 230009China School of Computer Science and Information Engineering Hefei University of TechnologyHefei 230009China

Nowadays,the personalized recommendation has become a research hotspot for addressing information *** this,generating effective recommendations from sparse data remains a ***,auxiliary information has been widely used to address data sparsity,but most models using auxiliary information are linear and have limited *** to the advantages of feature extraction and no-label requirements,autoencoder-based methods have become quite ***,most existing autoencoder-based methods discard the reconstruction of auxiliary information,which poses huge challenges for better representation learning and model *** address these problems,we propose Serial-Autoencoder for Personalized Recommendation(SAPR),which aims to reduce the loss of critical information and enhance the learning of feature ***,we first combine the original rating matrix and item attribute features and feed them into the first autoencoder for generating a higher-level representation of the ***,we use a second autoencoder to enhance the reconstruction of the data representation of the prediciton rating *** output rating information is used for recommendation *** experiments on the MovieTweetings and MovieLens datasets have verified the effectiveness of SAPR compared to state-of-the-art models.

关键词： personalized recommendation autoencoder representation learning collaborative filtering

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Periodic event-triggered secure consensus for networked mechanical systems under Denial-of-Service attacks

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Control Theory and Technology 2024年第1期22卷 1-13页

作者： Shiqi Zheng Zhipeng li Chao Zhai peng Shi School of Automation China University of GeosciencesWuhan430074HubeiChina School of Electrical and Electronic Engineering The University of AdelaideAdelaideSA5005Australia School of Electronic Electrical Engineering and PhysicsFujian University of TechnologyFuzhou350100FujianChina

This paper concentrates on the secure consensus problem of networked mechanical/Euler–Lagrange ***,a new periodic event-triggered(PET)secure distributed observer is proposed to estimate the leader *** proposed distributed observer only relies on the PET data from its neighbors,which can significantly reduce the communication and computational *** importantly,it is secure in the sense that it can work normally regardless of the Denial-of-Service(DoS)***,based on the proposed distributed observer,an adaptive fuzzy control law is proposed for each Euler–Lagrange system.A PET mechanism is integrated into the controller,which can reduce the control *** is helpful for both energy saving and fault tolerance of ***,the PET mechanism naturally makes the controller easy to be implemented in digital *** property of fuzzy logic systems and Gronwall inequality are skillfully utilized to show the stability of the closed-loop ***,the proposed control scheme is verified on real Euler–Lagrange systems,which contain a robot manipulator and several servo motors.

关键词： Output regulation Mechanical/Euler-Lagrange systems Periodic event-triggered mechanism Denial-of-Service attacks

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