检索结果-南通市图书馆

Adaptive dynamic programming for finite-horizon optimal control of linear time-varying discrete-time systems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Control Theory and Technology 2019年第1期17卷 73-84页

作者： bo PANG Tao BIAN zhong-Ping JIANG Control and Networks (CAN) Lab Department of Electrical and Computer Engineering Tandon School of Engineering New York University Brooklyn NY 11201 U.S.A. Bank of America Merrill Lynch One Bryant Park New York NY 70036 U.S.A.

This paper studies data-driven learning-based methods for the finite-horizon optimal control of linear time-varying discretetime systems. First, a novel finite-horizon Policy Iteration (PI) method for linear time-varying discrete-time systems is presented. Its connections with existing in finite-horizon PI methods are discussed. Then, both data-drive n off-policy PI and Value Iteration (VI) algorithms are derived to find approximate optimal controllers when the system dynamics is completely unknown. Under mild conditions, the proposed data-driven off-policy algorithms converge to the optimal solution. Finally, the effectiveness and feasibility of the developed methods are validated by a practical example of spacecraft attitude control.

关键词： Optimal control time-varying system adaptive dynamic programming policy iteration (PI) value iteration(VI)

Long-term adenosine A1 receptor activation-induced sortilin expression promotes α-synuclein upregulation in dopaminergic neurons

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第4期15卷 712-723页

作者： yun-Cheng Lv An-bo Gao Jing Yang Li-Yuan zhong bo Jia Shu-Hui Ouyang Le Gui Tian-Hong Peng Sha Sun Francisco S.Cayabyab Clinical Anatomy&Reproductive Medicine Application Institute Hengyang Medical CollegeUniversity of South ChinaHengyangHunan ProvinceChina Department of Surgery College of MedicineUniversity of SaskatchewanSaskatoonCanada Institute of Pharmacy and Pharmacology School of Pharmaceutical ScienceUniversity of South ChinaHengyangHunan ProvinceChina Department of Metabolism&Endocrinology the First Affiliated HospitalHengyang Medical CollegeUniversity of South ChinaHengyangHunan ProvinceChina

Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development of neurodegenerative ***,the pathogenesis underlying long-term adenosine A1 receptor activation-induced neurodegeneration remains *** this study,rats were intraperitoneally injected with 5 mg/kg of the adenosine A1 receptor agonist N6-cyclopentyladenosine(CPA)for five *** mobility of rats was evaluated by forced swimming test,while their cognitive capabilities were evaluated by Y-maze *** of sortilin,α-synuclein,p-JUN,and c-JUN proteins in the substantia nigra were detected by western blot *** addition,immunofluorescence staining of sortilin andα-synuclein was performed to detect expression in the substantia *** results showed that,compared with adenosine A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine(5 mg/kg)+CPA co-treated rats,motor and memory abilities were reduced,surface expression of sortin andα-synuclein in dopaminergic neurons was reduced,and total sortilin and totalα-synuclein were increased in CPA-treated ***9D cells were incubated with 500 nM CPA alone or in combination with 10μM SP600125(JNK inhibitor)for 48 *** real-time polymerase chain reaction analysis of sortilin andα-synuclein mRNA levels in MN9D cells revealed upregulated sortilin expression in MN9D cells cultured with CPA alone,but the combination of CPA and SP600125 could inhibit this *** made using Jasper,PROMO,and Alibaba online databases identified a highly conserved sequence in the sortilin promoter that was predicted to bind JUN in both humans and rodents.A luciferase reporter assay of sortilin promoter plasmid-transfected HEK293T cells confirmed this *** sortilin expression was inhibited by sh-SORT1,expression of p-JUN and c-JUN was detected by western blot ***-term adenosine A1 receptor activation levels upregulatedα-synuclein expression at the pos

关键词： cognitive dysfunction dopaminergic neuron dyskinesia JNK/c-JUN pathway long-term adenosine A1 receptor activation neural regeneration neurodegenerative diseases sortilin α-synuclein

Cloning and Expression Level Analysis of Two BnaANT Candidate Genes in Brassica napus

在线全文

学校读者我要写书评

暂无评论

Agricultural Sciences in China 2010年第4期9卷 488-496页

作者： CHEN bo WANG Tai-xia WANG Han-zhong LI yun-chang YAN Xiao-hong WANG Li-jun WEIWen-hui Institute of Oil Crops Chinese Academy of Agricultural Sciences/Key Laboratory for Biological Sciences of Oil Crops Ministry of Agriculture Wuhan 430062 P.R.China College of Life Sciences Henan Normal University Xinxiang 453007 P.R.China

AINTEGUMENTA （ANT） gene has been proved to have a novel function on controlling the organ size and the seed weight in Arabidopsis thaliana, the research on its orthologous gene in Brassica napus will be of potential interest to elucidate the molecular mechanism of rapeseed development and increase the rapeseed output. A SMART cDNA library of the flower bud from B. napus cultivar zhongshuang 9 was constructed, and the full-length cDNAs of two homologous BnaANT candidate genes were cloned by PCR in B. napus, namely ***.a （GenBank accession no. DQ211969） and ***.b （accession no. DQ211970）. They shared 87.1 and 83.4% amino acid identity with ANT of A. thaliana, respectively. There is 87.4% amino acid identity between ***.a and ***.b. By quantitative real-time PCR, the obviously differential expression levels of the two BnaANT candidate genes were detected in the 28 DAF seeds of the big and small grains B. napus lines, the expression abundance of BnaANT in the 28 DAF seed of 9311 was over three times compared to that of 9260, which indicates that these two BnaANT genes are also likely related to the floral organ size and the seed weight in B. napus.

关键词： AINTEGUMENTA gene Brassica napus BnaANT gene yield-related gene quantitative real-time PCR

Multifunctional protective aerogel with superelasticity over−196 to 500℃

在线全文

学校读者我要写书评

暂无评论

Nano Research 2022年第9期15卷 7797-7805页

作者： bo-Wen Liu Min Cao Yi-Ying Zhang Yu-zhong Wang Hai-bo Zhao The Collaborative Innovation Center for Eco-Friendly and Fire-Safety Polymeric Materials(MoE) National Engineering Laboratory of Eco-Friendly Polymeric Materials(Sichuan)State Key Laboratory of Polymer Materials EngineeringCollege of ChemistrySichuan UniversityChengdu 610064China

Protective materials that possess superelasticity and multifunctionality over a broad temperature range are urgently needed in various advanced ***,under harsh work conditions,the performance of current materials may largely deteriorate to lose protective ***,we report a bidirectionally oriented multi-walled carbon nanotubes(MWCNTs)-reinforced chitosan carbon aerogel(CS-MWCNT)that possesses superelasticity,high electromagnetic interference shielding,thermal insulation,and infrared stealth at both low temperatures(such as liquid nitrogen)and high temperatures(such as alcohol flames).Highly oriented lamellar arch structures combined with an MWCNTs-reinforced carbon skeleton act as elastic segments to disperse the stress during compression and endow CS-MWCNT with the ability to recover to almost the original size after being compressed at−196-500℃.The lamellar structures make CS-MWCNT thermally insulating and infrared stealth with a low thermal conductivity of~0.03 W/(m·K).Furthermore,a high electromagnetic interference(EMI)shielding effect of 64 dB is realized via an absorption-dominant EMI shielding mechanism derived from the successive inherently conductive carbon lamella,and the EMI shielding performance is largely maintained after treatment under extreme conditions like low temperature,high temperature,as well as cyclic *** work provides a new strategy for the development of temperature-invariant multifunctional aerogels for harsh environment applications.

关键词： superelasticity electromagnetic interference shielding heat insulation infrared stealth extreme environment

Effects of methyl-CD and humic acid on hydrolytic degradation of the herbicide diclofop-methyl

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2005年第1期17卷 67-71页

作者： CAIXi-yun WENYue-zhong zhongTian-xiang LIUWei-ping InstituteofEnvironmentScience ZhejiangUniversityHangzhou310029China

Hydrolytic degradation of the herbicide diclofop methyl was investigated in the multi pH deionized water, natural aquatic systems and soil suspensions. Resulting data indicated that the herbicide was stable in the acidic and nearly neutral solutions for at least 15 d. The herbicide diclofop methyl rapidly dissipated in the natural aquatic systems and soil suspensions with half lives less than 4 d. Methyl CD(partially methylated β cyclodextrin) improved its hydrolytic degradation in the pH 8 deionized water and natural aquatic systems while humic acid inhibited its hydrolytic degradation at the same conditions. But dissolved organic matter in the natural aquatic systems and soil suspensions increased its hydrolysis. Two catalysis mechanisms were introduced to describe the effects of cyclodextrin and organic matter on its hydrolytic metabolism. Though inorganic ions maybe improved its hydrolysis reaction in the natural aquatic systems, Fe 2+ and Cu 2+ did not form complexes with the herbicide and had poor influences on its hydrolytic degradation whether cyclodextrin was added or not.

关键词： diclofop-methyl methyl-CD organic matter humic acid hydrolysis

Antitumor efficacy of lidamycin on hepatoma and active moiety of its molecule

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2005年第26期11卷 3980-3984页

作者： yun-HongHuang bo-YangShang Yong-SuZhen InstituteofMedicinalBiotechnology ChineseAcademyofMedicalSciencesandPekingUnionMedicalCollegeBeijing100050China

AIM: To study the in vitro and in vivo antitumor effect of lidamycin (LDM) on hepatoma and the active moiety of its ***: MTT assay was used to determine the growth inhibition of human hepatoma BEL-7402 cells, SMMC-7721cells and mouse hepatoma H22 cells. The in vivo therapeutic effects of lidamycin and mitomycin C were determined by transplantable hepatoma 22 (H22) in mice and human hepatoma BEL-7402 xenografts in athymic ***: In terms of IC50values, the cytotoxicity of LDM was 10 000-fold more potent than that of mitomycin C (MMC)and adriamycin (ADM) in human hepatoma BEL-7402 cells and SMMC-7721 cells. LDM molecule consists of two moieties,an aproprotein (LDP) and an enediyne chromophore (LDC). In terms of IC50 values, the potency of LDC was similar to LDM. However, LDP was 105-fold less potent than LDM and LDC to hepatoma cells. For mouse hepatoma H22 cells, the IC50value of LDM was 0.025 nmol/L. Given by single intravenous injection at doses of 0.1, 0.05 and 0.025 mg/kg, LDM markedly suppressed the growth of hepatoma 22 in mice by 84.7%, 71.6% and 61.8%,respectively. The therapeutic indexes (TI) of LDM and MMC were 15 and 2.5, respectively. By 2 iv. Injections in two experiments, the growth inhibition rates by LDM at doses of 0.1, 0.05, 0.025, 0.00625 and 0.0125 mg/kg were 88.8-89.5%, 81.1-82.5%, 71.2-74.9%, 52.3-59.575%,and 33.3-48.3%, respectively. In comparison, MMC at doses of 5, 2.5, and 1.25 mg/kg inhibited tumor growth by 69.7-73.6%, 54.0-56.5%, and 31.5-52.2%,respectively. Moreover, in human hepatoma BEL-7402 xenografts, the growth inhibition rates by LDM at doses of 0.05 mg/kg ×2 and 0.025 mg/kg ×2 were 68.7%and 27.2%, respectively. However, MMC at the dose of 1.25 mg/kg ×2 showed an inhibition rate of 34.5%. The inhibition rate of tumor growth by LDM was higher than that by MMC at the tolerated ***: both LDM and its chromophore LDC display extremely potent cytotoxicity to hepatoma cells. LDM shows a remarkable therapeut

关键词： Lidamycin Hepatoma Mitomycin

Novel Solutions of KdV Equation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2004年第3期41卷 397-399页

作者： CHENZhe-yun BIJin-bo CHENDeng-Yuan DepartmentofMathematics ShanghaiUniversityShanghai200436China

Some novel solutions of the KdV equation are obtained through the modified bilinear B?cklund transformation.

关键词： novel solutions Hirota's method Backlund transformation KdV equation

Novel Silicon Nanotubes

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2001年第12期12卷 1139-1140页

作者： Hong bo CHEN Jing Dong LIN Jun YI yun CAI Guang WEI Yin zhong LIN Dai Wei LIAO Department of Chemistry Xiamen UniversityXiamen 361005 Department of Oceanography Xiamen UniversityXiamen 361005 State Key Lab of Physical Chemistry on Solid Surfaces Xiamen UniversityXiamen 361005 Institute of Physical Chemistry Xiamen UniversityXiamen 361005

Novel silicon nanotubes with inner-diameter of 60-80 nm was prepared using; hydrogen-added dechlorination of SiCl4 followed by chemical vapor deposition (CVD) on a NixMgyO catalyst. The TEM observation showed that the suitable reaction temperature is 973 K for the formation of silicon nanotubes. Most of silicon nanotubes have one open end and some have two closed ends. The shape of nanoscale silicon, however, isa micro-crystal type at 873 K, a rod or needle type at 993 K and an onion-type at 1023 K, respectively.

关键词： silicon nanotubes chemical vapor deposition chemical etching

在线全文

学校读者我要写书评

暂无评论

利用mtDNA信息分析陶寺古牛的起源驯化

农业生物技术学报 2025年第1期33卷 92-103页

作者：张兴杨柳侯凌云凌飞向海赵兴波华南理工大学生物科学与工程学院佛山大学动物科技学院/广东省动物分子设计与精准育种重点实验室中国农业大学动物科学技术学院/畜禽生物育种全国重点实验室

作为最重要的家畜之一，普通牛（bos taurus）在中国的起源和传播模式受到广泛关注。本研究收集了来自黄河中游3个考古遗址的9个古代牛遗骸，提取古DNA进行PCR测序和系统发生分析，以探索中国家养牛的起源和传播。经2轮PCR实验获得4个... 详细信息

作为最重要的家畜之一，普通牛（bos taurus）在中国的起源和传播模式受到广泛关注。本研究收集了来自黄河中游3个考古遗址的9个古代牛遗骸，提取古DNA进行PCR测序和系统发生分析，以探索中国家养牛的起源和传播。经2轮PCR实验获得4个陶寺（距今4100年前）古牛527 bp的线粒体DNA（mitochondrial DNA, mtDNA）序列。单倍型划分结果显示，陶寺古牛存在4种单倍型，都属于家养普通牛T3和T4单倍群，证实中国普通牛起源于近东地区，4 100年前就已经被华北人群利用。此外，陶寺遗址丰富的单倍型数量提示陶寺遗址古代牛群体具有较高的母系遗传多样性。群体间遗传分化指数FST（Fstatistics）分析和Median-Joining网络图表明，中国古代牛与现代东亚(FST=0.0164)及中国普通牛(FST=0.0066)均有密切的遗传关系，提示陶寺遗址古代牛群体可能是现代东亚和中国普通牛的重要母系祖先群体之一。本研究为解析我国的家牛起源和传播提供了分子遗传证据。

关键词：古代DNA 陶寺遗址普通牛起源