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Improved uncertainty propagation method of dynamic model for Mars entry spacecraft

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航空动力学报 2014年第5期29卷 1223-1233页

作者： FU Hui-min XIAO Qiang wu yun-zhang Research Center of Small Sample Technology Beijing University of Aeronautics and Astronautics

In order to research the uncertainty propagation laws of Mars entry dynamic equations for the Mars entry phase,an improved method was presented for analyzing the effect of the initial state uncertainties and uncertainty factor on the system state in the state *** applying the method to the entry phase of one of the NASA Mars exploration missions,the simulation results agreed well with the Monte Carlo method,especially the flight path angle simulation at least reaching 92%.It is found that the improved method can not only predict the uncertainty propagation laws with high accuracy of at least 92%in flight path angle simulation and large application scope from-0.1degree to 0.1degree,compared with local linearization method,but also save several hours relative to Monte Carlo method.

关键词：不确定性传播规律动态方程月出入高精度的改进方法

M1 muscarinic acetylcholine receptor in Alzheimer's disease

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Neuroscience Bulletin 2014年第2期30卷 295-307页

作者： Shangtong Jiang Yanfang Li Cuilin zhang Yingjun Zhao Guojun Bu Huaxi Xu yun-wu zhang Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research Institute of Neuroscience College of Medicine Xiamen University School of Pharmaceutical Sciences Xiamen University Degenerative Disease Research Program Sanford-Burnham Medical Research Institute

The degeneration of cholinergic neurons and cholinergic hypofunction are pathologies associated with Alzheimer＇s disease （AD）. Muscarinic acetylcholine receptors （mAChRs） mediate acetylcholine-induced neurotransmission and five mAChR subtypes （M1-M5） have been identified. Among them, M1 mAChR is widely expressed in the central nervous system and has been implicated in many physiological and pathological brain functions. In addition, M1 mAChR is postulated to be an important therapeutic target for AD and several other neurodegenerative diseases. In this article, we review recent progress in understanding the functional involvement of M1 mAChR in AD pathology and in developing M1 mAChR agonists forAD treatment.

关键词： agonist Alzheimer's disease amyloid cholinergic hypofunction M1 muscarinic acetylcholinereceptor tau

Advances in doping strategies for sodium transition metal oxides cathodes:A review

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Frontiers in Energy 2024年第2期18卷 141-159页

作者： Zhijing zhang Haoze zhang Yaopeng wu Wei YAN Jiujun zhang yun ZHENG Lanting QIAN Department of Chemical Engineering Waterloo Institute of NanotechnologyUniversity of WaterlooWaterloo ON N2L 3G1Canada School of Mechanical and Automotive Engineering South China University of TechnologyGuangzhou 510640China Institute of New Energy Materials Science and Engineering School of Materials Science and EngineeringFuzhou UniversityFuzhou 350108China

The electrochemistry of cathode materials for sodium-ion batteries differs significantly from lithium-ion batteries and offers distinct ***,the progress of commercializing sodium-ion batteries is currently impeded by the inherent inefficiencies exhibited by these cathode materials,which include insufficient conductivity,slow kinetics,and substantial volume changes throughout the process of intercalation and deintercalation ***,numerous methodologies have been utilized to tackle these challenges,encompassing structural modulation,surface modification,and elemental *** paper aims to highlight fundamental principles and strategies for the development of sodium transition metal oxide ***,it emphasizes the role of various elemental doping techniques in initiating anionic redox reactions,improving cathode stability,and enhancing the operational voltage of these cathodes,aiming to provide readers with novel perspectives on the design of sodium metal oxide cathodes through the doping approach,as well as address the current obstacles that can be overcome/alleviated through these dopant strategies.

关键词： sodium-ion batteries transition metal cathode doping strategy

Anti-Spoofing:Integrated Information Authentication of BeiDou-ⅡCivil Navigation Message

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China Communications 2024年第9期21卷 242-261页

作者： wu Zhijun Liang Cheng zhang yun Liu Rusen Yue Meng School of Safety Science and Engineering Civil Aviation University of ChinaTianjin 300300China School of Electronic Information and Automation Civil Aviation University of ChinaTianjin 300300China Dalian Air Traffic Management Station of Civil Aviation of China Dalian 116000China

The BeiDou-Ⅱcivil navigation message(BDⅡ-CNAV)is transmitted in an open environment and no information integrity protection measures are ***,the BDⅡ-CNAV faces the threat of spoofing attacks,which can lead to wrong location reports and time *** order to deal with this threat,we proposed a scheme of anti-spoofing for BDⅡ-CNAV based on integrated information *** scheme generates two type authentication information,one is authentication code information(ACI),which is applied to confirm the authenticity and reliability of satellite time information,and the other is signature information,which is used to authenticate the integrity of satellite location information and other *** authentication information is designed to embed into the reserved bits in BDⅡ-CNAV without changing the frame *** order to avoid authentication failure caused by public key error or key error,the key or public key prompt information(KPKPI)are designed to remind the receiver to update both keys in *** results indicate that the scheme can successfully detect spoofing attacks,and the authentication delay is less than 1%of the transmission delay,which meets the requirements of BDⅡ-CNAV information authentication.

关键词： anti-spoofing authentication BeiDou-II civil navigation message(BDII-CNAV) signature spoofing attack

Co_(3)O_(4)as an efficient passive NO_(x) adsorber for emission control during cold-start of diesel engines

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Chinese Journal of Chemical Engineering 2024年第2期66卷 1-7页

作者： Jinhuang Cai Shijie Hao yun zhang Xiaomin wu Zhenguo Li Huawang Zhao Department of Environmental Science&Engineering College of Chemical EngineeringHuaqiao UniversityXiamen 361021China wuxi Weifu Environmental Catalysts Co. LtdWuxi 214000China National Engineering Laboratory for Mobile Source Emission Control Technology China Automotive Technology&Research Center Co.Ltd.Tianjin 300300China

The Co_(3)O_(4)nanoparticles,dominated by a catalytically active(110)lattice plane,were synthesized as a low-temperature NO_(x) adsorbent to control the cold start emissions from *** nanoparticles boast a substantial quantity of active chemisorbed oxygen and lattice oxygen,which exhibited a NO_(x) uptake capacity commensurate with Pd/SSZ-13 at 100℃.The primary NO_(x) release temperature falls within a temperature range of 200-350℃,making it perfectly suitable for diesel *** characterization results demonstrate that chemisorbed oxygen facilitate nitro/nitrites intermediates formation,contributing to the NO_(x) storage at 100℃,while the nitrites begin to decompose within the 150-200℃***,lattice oxygen likely becomes involved in the activation of nitrites into more stable nitrate within this particular temperature *** concurrent processes of nitrites decomposition and its conversion to nitrates results in a minimal NO_(x) release between the temperatures of 150-200℃.The nitrate formed via lattice oxygen mainly induces the NO_(x) to be released as NO_(2) within a temperature range of 200-350℃,which is advantageous in enhancing the NO_(x) activity of downstream NH_(3)-SCR catalysts,by boosting the fast SCR reaction *** to its low cost,considerable NO_(x) absorption capacity,and optimal release temperature,Co_(3)O_(4)demonstrates potential as an effective material for passive NO_(x) adsorber applications.

关键词： Emission control Cold-start Low-temperature adsorption Co_(3)O_(4) Nitrate formation

Long-term potentiation-based screening identifies neuronal PYGM as a synaptic plasticity regulator participating in Alzheimer's disease

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动物学研究(英文) 2023年第5期44卷 867-881页

作者： Ting Wang yun-Qiang Zhou Yong Wang Liang zhang Xiang Zhu Xiu-Yan Wang Jing-Hui Wang Lin-Kun Han Jian Meng Xian zhang Hong Luo Qi-Lin Ma Zhan-Xiang Wang yun-wu zhang Xiamen Key Laboratory of Brain Center The First Affiliated Hospital of Xiamen Universityand Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging ResearchInstitute of NeuroscienceSchool of MedicineXiamen UniversityXiamenFujian 361102China Fujian Provincial Clinical Research Center for Brain Diseases The First Affiliated Hospital of Xiamen UniversityXiamenFujian 361003China

Synaptic dysfunction is an important pathological hallmark and cause of Alzheimer's disease(AD).High-frequency stimulation(HFS)-induced long-term potentiation(LTP)has been widely used to study synaptic plasticity,with impaired LTP found to be associated with ***,the exact molecular mechanism underlying synaptic plasticity has yet to be completely *** genes regulating synaptic plasticity are altered in AD and contribute to disease onset also remains ***,we induced LTP in the hippocampal CA1 region of wildtype(WT)and AD model mice by administering HFS to the CA3 region and then studied transcriptome changes in the CA1 *** identified 89 genes that may participate in normal synaptic plasticity by screening HFS-induced differentially expressed genes(DEGs)in mice with normal LTP,and 43 genes that may contribute to synaptic dysfunction in AD by comparing HFS-induced DEGs in mice with normal LTP and AD mice with impaired *** further refined the 43 genes down to 14 by screening for genes with altered expression in pathological-stage AD mice without HFS *** them,we found that the expression of Pygm,which catabolizes glycogen,was also decreased in AD *** further demonstrated that down-regulation of PYGM in neurons impaired synaptic plasticity and cognition in WT mice,while its overexpression attenuated synaptic dysfunction and cognitive deficits in AD ***,we showed that PYGM directly regulated energy generation in *** study not only indicates that PYGM-mediated energy production in neurons plays an important role in synaptic function,but also provides a novel LTP-based strategy to systematically identify genes regulating synaptic plasticity under physiological and pathological conditions.

关键词： Alzheimer's disease High-frequency stimulation Long-term potentiation PYGM Synaptic plasticity Transcriptome

The chemical characteristics of different sodium iron ethylenediaminetetraacetate sources and their relative bioavailabilities for broilers fed with a conventional corn‑soybean meal diet

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Journal of Animal Science and Biotechnology 2024年第2期15卷 826-843页

作者： Shengchen Wang Bingxin wu Ling Zhu Weiyun zhang Liyang zhang We wu Jiaqi wu yun Hu Tingting Li Xiaoyan Cui Xugang Luo College of Animal Science and Technology Yangzhou UniversityYangzhou 225000People’s Republic of China Mineral Nutrition Research Division State Key Laboratory of Animal NutritionInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijing 100193China

Background Our previous studies demonstrated that divalent organic iron(Fe)proteinate sources with higher complexation or chelation strengths as expressed by the greater quotient of formation(Qf)values displayed higher Fe bioavailabilities for *** iron ethylenediaminetetraacetate(NaFeEDTA)is a trivalent organic Fe source with the strongest chelating ligand ***,the bioavailability of Fe when administered as NaFeEDTA in broilers and other agricultural animals remains ***,the chemical characteristics of 12 NaFeEDTA products were *** these,one feed grade NaFeEDTA(Qf=2.07×10^(8)),one food grade NaFeEDTA(Qf=3.31×10^(8)),and one Fe proteinate with an extremely strong chelation strength(Fe-Prot ES,Qf value=8,590)were *** bioavailabilities relative to Fe sulfate(FeSO_(4)·7H_(2)O)for broilers fed with a conventional corn-soybean meal diet were evaluated during d 1 to 21 by investigating the effects of the above Fe sources and added Fe levels on the growth performance,hematological indices,Fe contents,activities and gene expressions of Fe-containing enzymes in various tissues of *** NaFeEDTA sources varied greatly in their chemical *** Fe concentration(PI),transferrin saturation(TS),liver Fe content,succinate dehydrogenase(SDH)activities in liver,heart,and kidney,catalase(CAT)activity in liver,and SDH mRNA expressions in liver and kidney increased linearly(P<0.05)with increasing levels of Fe ***,differences among Fe sources were detected(P<0.05)only for PI,liver Fe content,CAT activity in liver,SDH activities in heart and kidney,and SDH mRNA expressions in liver and *** on slope ratios from multiple linear regressions of the above indices on daily dietary analyzed Fe intake,the average bioavailabilities of Fe-Prot ES,feed grade NaFeEDTA,and food grade NaFeEDTA relative to the inorganic FeSO_(4)·7H_(2)O(100%)for broilers were 139%,155%,and 166%,***

关键词： Broilers Chelation strengths Fe-containing enzymes NaFeEDTA Relative bioavailabilities

Topological Structure-Modulated Collagen Carbon as Two-in-One Energy Storage Configuration toward Ultrahigh Power and Energy Density

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Energy & Environmental Materials 2024年第2期7卷 18-29页

作者： Li Yuan Wenlong Cai yunhong Wei Yiran Pu Can Liu yun zhang Hao wu College of Materials Science and Engineering Sichuan UniversityChengdu 610065China Department of Applied Chemistry University of Science and Technology of ChinaHefei 230026China

Efficient energy storage devices with suitable electrode materials,that integrate high power and high energy,are the crucial requisites of the renewable power source,which have unwrapped new possibilities in the sustainable development of energy and the ***,a facile collagen microstructure modulation strategy is proposed to construct a nitrogen/oxygen dual-doped hierarchically porous carbon fiber with ultrahigh specific surface area(2788 m^(2)g^(-1))and large pore volume(4.56 cm^(3)g^(-1))via local microfibrous breakage/disassembly of natural structured *** operando spectroscopy and density functional theory unveil that the dual-heteroatom doping could effectively regulate the electronic structure of carbon atom framework with enhanced electric conductivity and electronegativity as well as decreased diffusion resistance in favor of rapid pseudocapacitive-dominated Li^(+)-storage(353 mAh g^(-1)at 10 A g^(-1)).Theoretical calculations reveal that the tailored micro-/mesoporous structures favor the rapid charge transfer and ion storage,synergistically realizing high capacity and superior rate performance for NPCF-H cathode(75.0 mAh g^(-1)at 30 A g^(-1)).The assembled device with NPCF-H as both anode and cathode achieves extremely high energy density(200 Wh kg^(-1))with maximum power density(42600 W kg^(-1))and ultralong lifespan(80%capacity retention over 10000 cycles).

关键词： collagen carbon energy storage device theoretical calculations topological structure modulation ultrahigh power and energy density

Composition optimization and performance prediction for ultra-stable water-based aerosol based on thermodynamic entropy theory

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Defence Technology（防务技术） 2024年第3期33卷 437-446页

作者： Tingting Kang Canjun Yan Xinying Zhao Jingru Zhao Zixin Liu Chenggong Ju Xinyue zhang yun zhang Yan wu College of Chemical Engineering and Materials Science Tianjin University of Science and TechnologyNo.29 13th AvenueEconomic and Technologic Development ZoneTianjin 300457China Tianjin Key Laboratory of Brine Chemical Engineering and Resource Eco-utilization Tianjin University of Science and TechnologyTianjin 300457China College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073China

Water-based aerosol is widely used as an effective strategy in electro-optical countermeasure on the battlefield used to the preponderance of high efficiency,low cost and ***,the stability of the water-based aerosol is always unsatisfactory due to the rapid evaporation and sedimentation of the aerosol *** efforts have been devoted to improve the stability of water-based aerosol by using additives with different composition and ***,the lack of the criterion and principle for screening the effective additives results in excessive experimental time consumption and *** the stabilization time of the aerosol is still only 30 min,which could not meet the requirements of the perdurable ***,to improve the stability of water-based aerosol and optimize the complex formulation efficiently,a theoretical calculation method based on thermodynamic entropy theory is *** the factors that influence the shielding effect,including polyol,stabilizer,propellant,water and cosolvent,are considered within *** ultra-stable water-based aerosol with long duration over 120 min is obtained with the optimal fogging agent composition,providing enough time for fighting the electro-optic *** design guideline for choosing the additives with high phase transition temperature and low phase transition enthalpy is also proposed,which greatly improves the total entropy change and reduce the absolute entropy change of the aerosol cooling process,and gives rise to an enhanced stability of the water-based *** theoretical calculation methodology contributes to an abstemious time and space for sieving the water-based aerosol with desirable performance and stability,and provides the powerful guarantee to the homeland security.

关键词： Ultra-stable Water-based aerosol Thermodynamic entropy Composition optimization Performance prediction