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Prediction of Renal Function by Urinary Lead and Cadmium - Based on Classification Decision Tree and Logistic Regression Model

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Biomedical and Environmental Sciences 2024年第3期37卷 331-335页

作者： LI Yang wang qing Yao TIAN qing Hua AN qi YANG Yu Tong ZHANG Jia Chen LI Shuang Jing ZHOU Han LIANG yun Fen SHEN Wei Tong MU Li Na LEI Li Jian Department of Epidemiology School of Public HealthShanxi Medical UniversityTaiyuan 030001ShanxiChina Department of Epidemiology School of Public HealthShanxi Key Laboratory of Environmental Health Impairment and PreventionNHC Key Laboratory of PneumoconiosisMOE Key Laboratory of Coal Environmental Pathogenicity and PreventionShanxi Medical UniversityTaiyuan 030001ShanxiChina Department of Epidemiology and Environmental Health School of Public Health and Health ProfessionsThe State University of New York at BuffaloBuffaloNYUSA.

It is estimated that chronic kidney disease(CKD)will be the fifth leading cause of death in the world by 2040[1].Early recognition and intervention for kidney damage are *** glomerular filtration rate(eGFR)can be calculated by measuring blood creatinine to evaluate glomerular function,and urinary N-acetyl-β-δ-glucosaminidase(UNAG)level is generally recognized as a marker of renal tubular *** to lead(Pb)and cadmium(Cd)can damage renal function,leading to a decrease in eGFR and an increase in UNAG[2].Both Pb and Cd are easily accumulated in the body and then slowly released by the kidneys and ***,urinary Pb(UPb)and Cd(UCd)levels can be used as biomarkers of exposure[3,4].

关键词： urinary damage slowly

面向实施的城市更新单元规划编制技术框架与实践——以武汉为例

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规划师 2024年第4期40卷 98-105页

作者：汪云魏鹏张起彭阳武汉市自然资源保护利用中心同济大学武汉市自然资源保护利用中心社区治理博士工作室武汉市自然资源保护利用中心空间规划研究部

从城市更新单元的提出背景、研究与实践进展以及实施面临的困境出发,梳理城市更新单元规划的作用与地位,总结城市更新单元划定的要求,提出城市更新单元规划编制的侧重点以及技术框架和主要内容,在此基础上对武汉城市更新单元规划实践进... 详细信息

从城市更新单元的提出背景、研究与实践进展以及实施面临的困境出发,梳理城市更新单元规划的作用与地位,总结城市更新单元划定的要求,提出城市更新单元规划编制的侧重点以及技术框架和主要内容,在此基础上对武汉城市更新单元规划实践进行探索,以期为进一步完善城市更新单元规划编制、促进城市更新规划实施提供参考。

关键词：城市更新城市更新单元规划城市更新规划编制城市更新规划实施武汉

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Calculation of the energy dependence of fission fragments yields and kinetic energy distributions for neutron-induced ^(235)U fission

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Chinese Physics C 2024年第8期48卷 159-169页

作者： Ya-Ning Han Zheng Wei Yi-Xuan wang Dong-Ying Huo Peng-qi Zhang Ming Li Jun Ma Kang Wu Yong-Guang Zheng Yuan He Zhi-Yong Deng Tian-Zhi Jiang Xiang-Lin Zhuo Jin Li yun Zhang Yu Zhang Jun-Run wang Xiao-Dong Su Ze-En Yao School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China Engineering Research Center for Neutron Application Technology Ministry of EducationLanzhou UniversityLanzhou 730000China MOE Frontiers Science Center for Rare Isotopes Lanzhou UniversityLanzhou 730000China School of Mathematics and Statistics Lanzhou UniversityLanzhou 730000China Nuclear Power Institute of China Chengdu 610000China

Fission fragments yields and average total kinetic energy are fundamental nuclear data for nuclear energy applications and the study of nuclear *** fission products,such as ^(95)Zr,^(99)Mo,^(140)Ba,^(144)Ce,and ^(147)Nd,serve as burnup monitors,assessing the number of fissions induced by neutrons on ^(235)***,current experimental data for these fission products worldwide are inconsistent,introducing significant uncertainty into related scientific *** this study,we employed the Potential-driving Model to calculate the independent yields of ^(235)U and evaluate its advantages in such ***,we investigated the energy dependence of independent yields to select important ***,we calculated the cumulative yields of ^(95)Zr,^(99)Mo,^(140)Ba,^(144)Ce,and ^(147)Nd,and compared them with existing literature data to explore the energy dependence of fission products for ^(235)*** the lack of fission product yield data above 14.8 MeV,we extended our calculated incident neutron energy to 20 MeV,aiming to support future scientific *** Geant4 physical model does not consider the influence of incident neutron energy on the average total kinetic energy of fission fragments;thus,we introduced the excitation function of the total kinetic energy of fission fragments recommended by Madland et al.,which effectively describes the experimental data of the average total kinetic energy of fragments formed in ^(235)U *** this paper,we comprehensively discuss the energy dependence of fission product yields and average total kinetic energy.

关键词： ^(235)U(n f) potential-driving model fission yields kinetic energies energy dependence

区域资源生成赋能高质量发展:新质生产力的新引擎

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广东财经大学学报 2024年第4期39卷 4-12页

作者：王琪红陈云贤常远中山大学广东广州510275 广东财经大学财政税务学院广东广州510320

高质量发展需要以新的生产力理论为指导,而新质生产力是新时期经济高质量发展的内在要求和重要着力点。立足于中观经济学的区域资源生成理论,研究区域资源生成作为新质生产力的新引擎如何赋能经济高质量发展。研究指出,高质量发展归根... 详细信息

高质量发展需要以新的生产力理论为指导,而新质生产力是新时期经济高质量发展的内在要求和重要着力点。立足于中观经济学的区域资源生成理论,研究区域资源生成作为新质生产力的新引擎如何赋能经济高质量发展。研究指出,高质量发展归根到底是生产力的发展,而新质生产力是“新”与“质”的蜕变,是生产力在新一轮科技革命和产业变革下的跃升,是经济高质量发展的新源泉;区域资源生成是新质生产力的新引擎,资源生成领域的“三类资源”能催生新要素、新技术、新产业,是新质生产力的新力量;资源生成领域的“三个层面”可以突破关键技术、保证基本民生、推动绿色低碳,是新质生产力的新突破;资源生成领域的供给侧“三驾马车”从要素供给、环境供给、市场供给三个维度为新质生产力提供新动能;“有为政府”和“有效市场”是成熟市场经济的典型模式,成为区域资源生成推动经济高质量发展的新路径,同时要充分发挥有为政府的超前引领作用,以赋能高质量发展。

关键词：资源生成理论新质生产力高质量发展有为政府中观经济学

In-flight Energy Calibration of the GECAM Gamma-ray Detectors

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Research in Astronomy and Astrophysics 2024年第10期24卷 48-57页

作者： Rui qiao Dong-Ya Guo Wen-Xi Peng Yan-qiu Zhang Shuo Xiao Shao-Lin Xiong Chao Zheng Chao-Yang Li Jia-Cong Liu wang-Chen Xue Jian-Jian He Zheng-Hua An Da-Li Zhang Xin-qiao Li Li-Ming Song Shi-Jie Zheng Ke Gong Ya-qing Liu Xin-Ying Song Xiao-yun Zhao Xiang-Yang Wen Yan-Bing Xu Xiang Ma Xiao-Bo Li Ping wang Yue Huang Ce Cai qi-Bin Yi Yi Zhao Chen-Wei wang Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China China West Normal University Nanchong 637002China Xiangtan University Xiangtan 411105China Beijing Normal University Beijing 100875China

The Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)mission is designed to monitor the Gamma-Ray Bursts(GRBs)associated with gravitational waves and other high-energy transient *** mission consists of two microsatellites which are planned to operate at the opposite sides of the *** GECAM satellite could detect and localize GRBs in about 8 keV-5 MeV with its 25 Gamma-Ray Detectors(GRDs).In this work,we report the in-flight energy calibration of GRDs using the characteristic gamma-ray lines in the background spectra,and show their performance evolution during the commissioning ***,a preliminary cross-calibration of energy response with Fermi GBM data is also presented,validating the energy response of GRDs.

关键词： (stars:)gamma-ray burst:general instrumentation:detectors methods:data analysis

基于低场核磁共振技术的致密砂岩气藏防水锁作用机理研究

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科学技术与工程 2024年第4期24卷 1459-1470页

作者：马伟云黄凯王鹏杨帆杨琦安琦王琛中联煤层气有限责任公司北京100015 “三气共采”省级技术创新中心太原030000 西安石油大学石油工程学院西安710065 西安市致密油(页岩油)开发重点实验室西安710065

致密砂岩气藏孔隙度、渗透率较低,微观孔喉尺度细小,在生产及压裂过程中极易产生水锁伤害。为开展致密储层防水锁作用机理研究,将常规岩心自吸实验、防水锁剂抑制水锁伤害实验与低场核磁共振技术(nuclear magnetic resonance,NMR)相结合... 详细信息

致密砂岩气藏孔隙度、渗透率较低,微观孔喉尺度细小,在生产及压裂过程中极易产生水锁伤害。为开展致密储层防水锁作用机理研究,将常规岩心自吸实验、防水锁剂抑制水锁伤害实验与低场核磁共振技术(nuclear magnetic resonance,NMR)相结合,从微观角度揭示致密砂岩储层微纳米级孔喉中的防水锁作用机理,为致密砂岩气藏防水锁相关研究提供理论依据。结果表明:加入防水锁添加剂后,流体表面张力下降,接触角增大,自吸速率变慢,渗透率有一定程度恢复;在此基础上,通过核磁共振T 2谱从微观角度评价缓慢自吸阶段液体在不同孔喉尺度范围内的液相水锁滞留现象,其中加入防水锁添加剂后在自吸20 h时在较小孔喉处自吸液相平均占比为38.61%,整体孔喉平均液相占比为35.79%。而在未加入防水锁试剂的样品中在自吸20 h时在较小孔喉处液相占比为67.48%,整体孔喉占比为54.52%;通过防水锁剂抑制水锁伤害实验得出,加入防水锁剂后渗透率恢复程度在15.38%~20.19%,整体液相滞留占比平均下降幅度在10.73%。防水锁剂有效地降低较小孔候处液相滞留占比,降低流体表面张力以及增大岩心疏水性能,揭示了致密砂岩气藏防水锁作用机理,为致密砂岩气藏降低水锁伤害程度、提高返排效率,为实现高效开发提供理论支撑。

关键词：防水锁剂核磁共振技术(NMR) 毛管自吸水锁伤害致密砂岩气藏

Guicao Baidu decoction in mitigating chemotherapy-induced myocardial injury:case report and mechanism investigation

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Natural Therapy Advances 2024年第3期7卷 29-36页

作者： Jia-qi Fu Run-Jie Sun Man-Ya Yu Mu-yun Wu Xing Cui The First School of Clinical Medicine Shandong University of Traditional Chinese MedicineJinan 250014China Center of Oncology and Hematology The Second Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250001China

To observe the effects of GuiCaoBaiDu Decoction(GCBD)on chemotherapy especially doxorubicin(DOX)-induced myocardial cardiotoxicity(DIC)and explore the *** present study presents a case demonstrating the preventive and therapeutic effects of GCBD on myocardial injury following *** network pharmacology was employed to predict the targets of ***,a DOX-induced apoptosis model of H9C2 cardiomyocytes was established and co-cultured with serum containing GCBD *** viability and myocardial enzyme levels were evaluated using CCK8 assay and ELISA assay,TUNEL was using for apoptosis *** GCBD effect was confirmed by tests of ROS andα-actinin levels,evaluation of mitochondrial morphology,and BAX co-localization with ***,the expression levels of apoptosis-related molecules were determined via Western ***,a mouse model exhibiting DOX-induced cardiac functional impairment was generated and subsequently treated with *** enzyme level was tested at first,then echocardiography was tested,myocardial apoptosis in mice was observed through HE staining while related proteins were detected using *** pharmacological analyses revealed that GCBD exerts its effects on BAX,Caspase7,and other related ***,we demonstrated the effective amelioration of DIC in cardiomyocyte viability,LDH/CK levels,α-actinin and ROS levels,and apoptosis by GCBD through improvements in TUNEL test,mitochondrial morphology and *** efficacy of GCBD in enhancing cardiac function in DIC mice has been validated through animal *** together,our study showed that GCBD could significantly alleviate DOX induced myocardial injury by regulating mitochondrial *** utilization of GCBD can effectively contribute to the prevention and treatment of chemotherapy-induced myocardial injury when anthracycline chemotherapy is employed in clinical practice.

关键词： Guicao Baidu decoction chemotherapy-induced myocardial injury case report angiogenesis

稳定性铯对土壤养分、酶活性与微生物群落功能多样性的影响

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草地学报 2024年第8期32卷 2478-2483页

作者：亓琳王晓凌赵威包云河南科技大学农学院河南洛阳471023

铯(Cs)与钾(K)的化学行为极其相似,进入人体后的Cs大量聚集到肌肉和肝脏中。为研究稳定性铯-133(133 Cs)的生物毒性,本研究采用133 Cs,通过微宇宙培养试验,设置3个铯处理浓度:5 mg·kg^(-1)Cs(CK),100 mg·kg^(-1)Cs(L)和500 mg·kg^(-1... 详细信息

铯(Cs)与钾(K)的化学行为极其相似,进入人体后的Cs大量聚集到肌肉和肝脏中。为研究稳定性铯-133(133 Cs)的生物毒性,本研究采用133 Cs,通过微宇宙培养试验,设置3个铯处理浓度:5 mg·kg^(-1)Cs(CK),100 mg·kg^(-1)Cs(L)和500 mg·kg^(-1)Cs(H),研究了金属铯对土壤理化性质和微生物群落功能多样性和酶活性的影响。结果表明,Cs处理中有机质含量和速效钾与CK相比显著减少(P<0.05),在H处理中分别降低了13.54%和8.37%。Cs显著降低了转化酶、磷酸酶、脲酶和脱氢酶活性(P<0.05),且随着Cs浓度的增加,其抑制效应增强,在H处理中分别减少了21.1%,22.5%,22.6%和21.8%。Cs显著降低了Shannon多样性指数、Shannon均匀度指数和碳源利用丰富度指数(P<0.05)。以上结果表明金属铯污染显著降低土壤微生物群落的功能多样性,降低了土壤养分含量,抑制了土壤酶活性,该研究为133 Cs污染土壤的风险控制提供理论基础。

关键词：铯土壤微生物土壤养分酶活性

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三峡库区N_(2)O时空分布差异及减排潜力分析

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长江流域资源与环境 2024年第1期33卷 150-162页

作者：李丹青王云琦王震白志杰李海涛北京林业大学水土保持学院北京100085 北京林业大学水土保持学院重庆缙云山三峡库区森林生态系统国家定位观测研究站北京100083 呼伦贝尔农垦集团内蒙古呼伦贝尔021008 呼伦贝尔水文勘测局内蒙古呼伦贝尔021099

氧化亚氮(N_(2)O)是继二氧化碳(CO_(2))和甲烷(CH4)之后的全球第三大温室气体,地区的农业集约化发展和城镇化推进会加剧N_(2)O排放。基于此选取三峡库区为典型地区,利用IPCC排放因子法和情景分析法对三峡库区N_(2)O时空分布差异及减排... 详细信息

氧化亚氮(N_(2)O)是继二氧化碳(CO_(2))和甲烷(CH4)之后的全球第三大温室气体,地区的农业集约化发展和城镇化推进会加剧N_(2)O排放。基于此选取三峡库区为典型地区,利用IPCC排放因子法和情景分析法对三峡库区N_(2)O时空分布差异及减排潜力进行研究。结果表明:(1)三峡库区2006年~2019年N_(2)O排放量维持在1.47~1.62万t,总体趋势呈先升高后降低且库区内18个区县间差异性较为显著(P<0.01),空间分布具有随机性(14年年均Moran I≈0)。(2)三峡库区农业活动是三峡库区N_(2)O最主要的来源,而化肥施用量和粪便排放量是库区农业N_(2)O最大来源,占比为40.48%和23.84%。利用STIRPAT模型发现N_(2)O驱动因素中,城镇化率对三峡库区有控制作用,促进因子从小到大依次为粮食产量、乡村从业人数、第一产业增值和人均GDP。(3)利用情景分析法在3种减排情景下对三峡库区2030年N_(2)O排放量进行预测,预测值分别为1.55、1.34和1.21万t。针对三峡库区N_(2)O排放情况和未来预测情况,建议从库区腹部地带着手,控制农田氮肥施用量和加强畜禽粪便管理,建立种养结合新农业模式,探索减排过程中的土壤内部循环机理,多方面联合控制N_(2)O的排放。

关键词：温室气体氧化亚氮三峡库区 IPCC 农业低碳