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Genetic effects on serum testosterone and sex hormone-binding globulin in men： a Korean twin and family study

Asian Journal of Andrology 2016年第5期18卷 786-790页

作者： Joohon Sung yun-mi song Department of Epidemiology School of Public Health Seoul National University Seou1151-742 South Korea Institute of Health Environment Seoul National UniversitySeou1151-742 South Korea Department of Family Medicine Samsung Medical Center and Center for Clinical Research Samsung Biomedical Research InstituteSungkyunkwan University School of Medicine Seou1135-710 South Korea

We conducted a community-based cross-sectional study to evaluate the role of genetics in determining the individual difference in total testosterone and sex hormone-binding globulin levels. Study participants comprised 730 Korean men consisting of 142 pairs of monozygotic twins, 191 pairs of siblings, and 259 father-offspring pairs from 270 families who participated in the Healthy Twin study. Serum concentration of total testosterone and sex hormone-binding globulin were measured by chemiluminescence immunoassay, and free testosterone and bioavailable testosterone were calculated using Vermeulen＇s method. Quantitative genetic analysis based on a variance decomposition model showed that the heritability of total testosterone, free testosterone, bioavailable testosterone, and sex hormone-binding globulin were 0.56, 0.45, 0.44, and 0.69, respectively after accounting for age and body mass index. Proportions of variance explained by age and body mass index varied across different traits, from 8% for total testosterone to 31% for sex hormone-binding globulin. Bivariate analysis showed a high degree of additive genetic correlation （p~ = 0.67） and a moderate degree of individual-specific environmental correlation （PE = 0.42） between total testosterone and sex hormone-binding globulin. The findings confirmed the important role of genetics in determining the individually different levels of testosterone and sex hormone-binding globulin during adulthood in Korean men as found in non-Asian populations, which may suggest that common biologic control for determining testosterone level directly or indirectly through binding protein are largely shared among different populations.

关键词： genetics Korean sex hormone-binding globulin testosterone twin study

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马铃薯转录因子StFBH3对非生物逆境胁迫的响应分析

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作物学报 2025年第1期51卷 247-259页

作者：宋倩娜宋慧洋李京昊段永红梅超冯瑞云山西农业大学农学院山西太谷030801 山西省农业科学院作物科学研究所山西太原030031

bHLH (basic helix-loop-helix)作为植物界第二大类转录因子,在植物应对环境胁迫响应中起着重要的调控作用。探究马铃薯(Solanum tuberosum L.) bHLH家族基因功能将为马铃薯改良和育种提供一定的理论依据。本研究克隆了马铃薯StFBH3基因... 详细信息

bHLH (basic helix-loop-helix)作为植物界第二大类转录因子,在植物应对环境胁迫响应中起着重要的调控作用。探究马铃薯(Solanum tuberosum L.) bHLH家族基因功能将为马铃薯改良和育种提供一定的理论依据。本研究克隆了马铃薯StFBH3基因(Gene ID:102582309),利用qPCR技术分析了不同逆境胁迫下StFBH3基因表达模式,结果表明, StFBH3基因在马铃薯根和叶中的表达量较高,且该基因的表达受渗透、高盐和脱落酸(abscisic acid, ABA)诱导;以过表达StFBH3基因的马铃薯试管苗为材料,在分别含有不同浓度甘露醇(mannitol)、NaCl和ABA的MS培养基中,过表达StFBH3马铃薯株系的叶绿素含量显著高于野生型,根长显著长于野生型。在干旱和高盐处理下,土壤栽培的过表达马铃薯株系较野生型表现较强的耐受性,叶片相对含水量、叶绿素含量和过氧化物歧化酶(SOD)活性显著高于野生型。qPCR分析发现,干旱和盐胁迫处理下相关基因(KAT1)的表达量在过表达马铃薯株系中较野生型显著降低。以上结果表明, StFBH3基因可能在马铃薯对渗透、干旱和高盐等胁迫响应中起正向调控作用。本研究也为StFBH3基因在马铃薯中的生物学功能深入理解提供一定的参考依据。

关键词：马铃薯 StFBH3 转录因子逆境胁迫

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Genus two correlation functions in CFTs with TT deformation

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Science China(Physics,Mechanics & Astronomy) 2023年第5期66卷 106-119页

作者： song He yun-Ze Li Center for Theoretical Physics and College of Physics Jilin UniversityChangchun 130012China Max Planck Institute for Gravitational Physics(Albert Einstein Institute) Am Mühlenberg 114476 GolmGermany

Since the definition of TT deformation in the curved Riemann surface is obstructive in the literature,we propose a way to do the deformation in the genus two Riemann surfaces by sewing *** construct the correlation functions of conformal field theories(CFTs)on genus two Riemann surfaces with the TT deformation in terms of the perturbative CFT *** to sewing construction to form higher genus Riemann surfaces from lower genus ones and conformal symmetry,we systematically obtain the first-order TT correction to the genus two correlation functions in the TT deformed CFTs,e.g.,partition function and one/higher-point correlation functions.

关键词： conformal field theory gauge/gravity duality TT deformation higher genus correlation function

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Martensitic transformation of Ti-18Nb(at.%) alloy with zirconium

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Rare Metals 2012年第3期31卷 227-230页

作者： Ye, Wenjun mi, Xujun song, Xiaoyun State Key Laboratory for Nonferrous Metals and Process General Research Institute for Nonferrous Metals Beijing 100088 China

The addition of 3%～9% Zr on the martensitic transformation of Ti-18Nb(at.%) alloy was investigated. The results of microstructure and X-ray diffraction (XRD) analysis show that the phase constitution of as-quenched Ti-18Nb-9Zr(at.%) alloy consists of the retained matrix and martensite, while that of the other three alloys is single martensite. No trace of athermal phase was found in any of the as-quenched alloys. Unlike the effect of Nb addition on the martensitic transformation start temperature Ms of Ti-18Nb(at.%) alloy, Ms de-creased nonlinearly as increasing the Zr addition from 3% to 9% and Ms decreased much more sharply as increasing the Zr addition. The Ms of as-quenched Ti-18Nb-9Zr alloy was around room temperature. The effect of Zr addition on the phase stabilizing in the Ti-18Nb(at.%) alloy was briefly discussed.

关键词： titanium alloy martensitic transformation alloying effect

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Change of Arctic sea-ice volume and its relationship with sea-ice extent in CmiP5 simulations

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Atmospheric and Oceanic Science Letters 2016年第1期9卷 22-30页

作者： song mi-Rong State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of Sciences

The future change of September Arctic sea-ice volume,simulated by 30 state-of-the-art climate models from the Coupled Model Intercomparison Project Phase 5（CmiP5）,is examined,which depends on both ice extent and ice *** comparison with the September sea-ice extent,the September sea-ice volume has larger spread in the historical simulation but faster convergence in the projection simulation,especially in the context of increasing greenhouse gas *** indicates that the ice volume might be more sensitive to external forcings than the ice *** the averaged projection of those climate models from the 30 CmiP5 models that can better reflect the ‘observed＇ sea-ice volume climatology and variability,it is shown that the September sea ice volume will decrease to ~3000 km3 in the early 2060 s,and then level off under a medium-mitigation ***,it will drop to ~3000 km3 in the early 2040 s and reach a near-zero ice volume in the mid-2070 s under a high-emission *** respect to the historical condition,the reduction of the ice volume,associated with increasing greenhouse gas emissions,is more rapid than that of the ice extent during the twenty-first century.

关键词： sea-ice volume sea-ice extent sea-ice thickness cmip5

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Compressed data separation via dual frames based split-analysis with Weibull matrices

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Applied Mathematics(A Journal of Chinese Universities) 2013年第4期28卷 427-437页

作者： CAI yun LI song Department of Mathematics Zhejiang University

In this paper, we consider data separation problem, where the original signal is composed of two distinct subcomponents, via dual frames based Split-analysis approach. We show that the two distinct subcomponents, which are sparse in two diff erent general frames respectively, can be exactly recovered with high probability, when the measurement matrix is a Weibull random matrix （not Gaussian） and the two frames satisfy a mutual coherence property. Our result may be significant for analysing Split-analysis model for data separation.

关键词： Compressed sensing data separation dual frames split-analysis Weibull random matrices

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Convergence analysis of projected gradient descent for Schatten-p nonconvex matrix recovery

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Science China Mathematics 2015年第4期58卷 845-858页

作者： CAI yun LI song Department of Mathematics Zhejiang University

The matrix rank minimization problem arises in many engineering applications. As this problem is NP-hard, a nonconvex relaxation of matrix rank minimization, called the Schatten-p quasi-norm minimization(0 minimization(0 < p < 1) *** on the matrix restricted isometry property(M-RIP), we give the convergence guarantee and error bound for this algorithm and show that the algorithm is robust to noise with an exponential convergence rate.

关键词： low rank matrix recovery nonconvex matrix recovery projected gradient descent restricted isometry property

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microstructural evolution and mechanical properties of Ni-45Ti-5Al-2Nb-1Mo alloy subjected to different heat treatments

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Rare Metals 2023年第8期42卷 2774-2780页

作者： Xiao-yun song Yan Li Fei Zhang State Key Laboratory of Nonferrous Metals and Processes GRIMAT Engineering Institute Co.LtdBeijing 101407China School of Materials Science and Engineering Beihang UniversityBeijing 100191China

The effects of solution and aging heat treatment on microstructural evolution and room temperature tensile properties for as-forged Ni-45Ti-5Al-2Nb-1Mo alloy were investigated through scanning electron microscopy(SEM),transmission electron microscopy(TEM)and tensile *** results show that the microstructure of solution-treated alloy comprises NiTi matrix,Ti_(2)Ni and(Nb,Ti)ss *** aging treatment at 700℃for 6 and100 h,the distribution of Ti_(2)Ni and(Nb,Ti)ss precipitates increases in *** new type of precipitate is observed in the specimen aged at 700℃.After aging at800℃for 100 h,numerous nanosized Ni_(2)TiAl phases are precipitated within the *** and aging treatments improve the tensile properties at room *** strength and ductility are improved after solution treatment at 1100℃plus aging treatment at 800℃for 6 h or 700℃for 100 *** aging time prolonging to 100 h at 800℃,the precipitation of fine Ni2TiAl particles leads to the improvement in tensile strength and deterioration of elongation.

关键词： NiTi-Al-based alloy Intermetallics microstructure Mechanical properties Heat treatment

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Projection of residential and commercial electricity consumption under SSPs in Jiangsu province, China

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Advances in Climate Change Research 2020年第2期11卷 131-140页

作者： ZHANG mi CHENG Chin-Hsien MA Hong-yun Key Laboratory of Meteorological Disaster Ministry of Education(KLME)Nanjing University of Information Science and TechnologyNanjing210044China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD) Nanjing University of Information Science and TechnologyNanjing210044China Institute for Climate and Application Research(ICAR) Nanjing University of Information Science and TechnologyNanjing210044China

Future electricity consumption may increase due to climate change,but the amplitude depends on the interaction between many uncertain *** on the linear model and policy model,the residential and commercial electricity consumption in Jiangsu province are projected under the shared socioeconomic pathways(SSPs).The linear model considers climate and socioeconomic factors,and the policy model also takes policy factors into *** find that the cooling degree days(CDD)coefficient is about 3 times of heating degree days(HDD),which reflects that the cooling demand is much larger than heating,and also shows in the *** results of the policy model are generally lower than the linear model,which is the impact of policy *** example,the SSP1 and SSP2 of the policy model are 320 TW h and 241.6 TW h lower than the linear model in 2100,*** the end of the 21st century,the residential and commercial electricity consumption in Jiangsu province will reach 107.7–937.9 TW h per year,1.3–11.6 times of *** SSP1 scenario under the policy model is based on feasible assumptions,and can be used as the target scenario for policymakers to establish energy intensity reduction targets.

关键词： Electricity consumption Residential and commercial Climate change Projection SSP

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Spatial non-stationary characteristics between temperate grasslands based on a mixed geographically weighted regression model

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Journal of Geographical Sciences 2022年第6期32卷 1076-1102页

作者： song Xiaolong mi Nan mi Wenbao LI Longtang College of Agriculture Ningxia UniversityYinchuan 750021China School of Geography and Planning Ningxia UniversityYinchuan 750021China

Spatial models are effective in obtaining local details on grassland biomass,and their accuracy has important practical significance for the stable management of grasses and *** this end,the present study utilized measured quadrat data of grass yield across different regions in the main growing season of temperate grasslands in Ningxia of China(August 2020),combined with hydrometeorology,elevation,net primary productivity(NPP),and other auxiliary data over the same ***,non-stationary characteristics of the spatial scale,and the effects of influencing factors on grass yield were analyzed using a mixed geographically weighted regression(MGWR)*** results showed that the model was suitable for correlation *** spatial scale of ratio resident-area index(PRI)was the largest,followed by the digital elevation model,NPP,distance from gully,distance from river,average July rainfall,and daily temperature range;whereas the spatial scales of night light,distance from roads,and relative humidity(RH)were the most *** influencing factors maintained positive and negative effects on grass yield,save for the strictly negative effect of *** regression results revealed a multiscale differential spatial response regularity of different influencing factors on grass *** parameters revealed that the results of Ordinary least squares(OLS)(Adjusted R^(2)=0.642)and geographically weighted regression(GWR)(Adjusted R^(2)=0.797)models were worse than those of MGWR(Adjusted R^(2)=0.889)*** on the results of the RMSE and radius index,the simulation effect also was MGWR>GWR>OLS ***,the MGWR model held the strongest prediction performance(R^(2)=0.8306).Spatially,the grass yield was high in the south and west,and low in the north and east of the study *** results of this study provide a new technical support for rapid and accurate estimation of grassland yield to dynamically adjust grazing decision in the semi-ar

关键词： grass yield spatial non-stationary mixed geographically weighted regression model temperate grassland Ningxia

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