检索结果-南通市图书馆

Reduction of Elemental Selenium by Samarium Diiodide: the Synthesis of Dithiodiselenides and Dithioselenides

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2001年第5期12卷 379-382页

作者： Hong yun GUO yun Fa zheng Yong Min ZHANG Department of Chemistry Zhejiang University at Xixi CampusHangzhou 310028 Department of Chemistry Zhejiang Normal UniversityJinhua 321004 Department of Chemistry Lishui Teachers CollegeZhejiang 323000

The reduction of elemental selenium by samarium diiodide led to selective formation of selenolate anion species (Se-2(2-) and Se2-), these nucleophilic species reacted readily with sodium alkyl thiosulfates to afford ... 详细信息

关键词： Synthesis samarium diiodide dithiodiselenides dithioselenides.

Cellular reprogramming and hepatocellular carcinoma development

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第47期19卷 8850-8860页

作者： yun-Wen zheng yun-Zhong Nie Hideki Taniguchi Department of Regenerative Medicine Graduate School of MedicineYokohama City UniversityKanazawa-kuYokohamaKanagawa 236-0004Japan Jiangsu University Hospital Advanced Medical Research Center Yokohama City UniversityYokohamaKanagawa 236-0004Japan

Hepatocellular carcinoma(HCC)is one of the most common cancers,and is also the leading cause of death *** have shown that cellular reprogramming contributes to chemotherapy and/or radiotherapy resistance and the recurrence of *** this article,we summarize and discuss the latest findings in the area of cellular reprogramming in *** aberrant expression of transcription factors OCT4,KLF4,SOX2,c-MYC,NANOG,and LIN28 have been also observed,and the expression of these transcription factors is associated with unfavorable clinical outcomes in *** indicate that cellular reprogramming may play a critical role in the occurrence and recurrence of *** reports have shown that DNA methylation,miRNAs,tumor microenvironment,and signaling pathways can induce the expression of stemness transcription factors,which leads to cellular reprogramming in ***,studies indicate that therapies based on cellular reprogramming could revolutionize HCC ***,a novel therapeutic concept is discussed:reprogramming control therapy.A potential reprogramming control therapy method could be developed based on the reprogramming demonstrated in HCC studies and applied at two opposing levels:differentiation and *** increasing understanding and control of cellular programming should facilitate the exploitation of this novel therapeutic concept and its application in clinical HCC treatment,which may represent a promising strategy in the future that is not restricted to liver cancer.

关键词： Reprogramming Hepatocellular carcinomas Cancer stem cells Transcription factor Therapeutics

Crystal Structure of Dimethylamine 3,5-Dinitrobenzoic Acid Organic Adduct

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2006年第8期25卷 1011-1013页

作者： ZHU Jun ZHANG yun CHEN Hao CHE yun-Xia zheng Ji-Min Department of Chemistry Nankai University lianjin 300071 China

The title adduct （C9H11N3O6, Mr= 257.21） was synthesized and it crystallizes in orthorhombic, space group P212121 with a = 5.8835（19）, b =9.517（3）, c = 20.399（6） A, V= 1142.2（6） ,A^3 Z = 4, Dc= 1.496 g/cm^3, F（000） = 536,μ（MoKα） = 0.128 mm^-1, the final R = 0.0396 and wR = 0.0800 for 1047 observed reflections with I 〉 2σ（I）. The compound is a 1：1 adduct of dimethylamine and 3,5-dinitrobenzoic acid which are linked by hydrogen bonds to form a two-dimensional network. The dimethylamine is protonated at the nitrogen atom with the proton from the carboxyl of 3,5- dinitrobenzoic acid.

关键词： dimethylamine 3,5-dinitrobenzoic acid hydrogen bond crystal structure nonlinear optical

Hydrothermal Synthesis and Crystal Structure of a Heterometallic Cu/Cd Complex with H_2dipic(Pyridine-2,6-dicarboxylic Acid)

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2006年第10期25卷 1250-1254页

作者： XUE Lin CHE yun-Xia zheng Ji-Min Department of Chemistry Nankai University Tianjin 300071 China

A new heterometallic complex {[Cu（pic）2（H2O）2][Cd2（Hdipic）2（H2O）2Cl2]}n （Mr = 1007.73） has been synthesized under hydrothermal condition and characterized by single-crystal X-ray diffraction. It crystallizes in triclinic, space group PI^- with a = 5.8397（4）, b = 9.8664（7）, c = 14.1739（10） °A, α= 82.0150（10）, β = 80.4540（10）, γ= 82.3570（10）°, Z= 1, V= 792.47（10）°A^3, Dc = 2.112 g/cm^3,μ（MoKα） = 2.247 mm^-1, F（000） = 495, the final R = 0.0232 and wR = 0.0644 for 2748 observed reflections （I〉 2σ（I））. In the complex, seven-coordinated·Cd ions form a zigzag chain based on the alternated dinuclear Cd units. The neutral [Cu（pic）2（H2O）2] units are located at the centers of the inter space and fasten to the 1-D chain by hydrogen bonds.

关键词： copper cadmium heterometallic dinuclear hydrothermal coordination polymer

Crystal Structure of a Nickel(II) Complex with Asymmetric _L-Histidine Ligand

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2006年第9期25卷 1047-1050页

作者： JIN Yi CHE yun-Xia zheng Ji-Min Department of Chemistry Nankai University Tianjin 300071 China

A novel nickel（Ⅱ） complex with L-histidine has been synthesized and solved by single-crystal X-ray diffraction analysis at physiological pH. The title complex （C7H16NiN4O6S, Mr = 343.01） crystallizes in monoclinic, space group P21 with a = 7.2194（7）, b = 7.5968（7）, c = 12.2797（11） A, β = 93.3110（10）°, V = 672.35（11） A^3, Z = 2, Dc= 1.694 g/cm^3, F（000） = 356, μ（MoKα） = 1.626 mm^-1, T = 293（2） K, the final R = 0.0184 and wR = 0.0426 for 2207 observed reflections with 1 〉 2σ（I）. The complex provides insights into a possible structural arrangement between nickel （Ⅱ） and L-histidine which may be physiologically important and abundantly present in biological systems.

关键词： crystal structure synthesis L-histidine nickel physiological pH

Dual Attribute Adversarial Camouflage toward camouflaged object detection

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2023年第4期22卷 166-175页

作者： Yang Wang zheng Fang yun-fei zheng Zhen Yang Wen Tong Tie-yong Cao Institute of Command and Control Engineering Peoples Liberation Army Engineering UniversityNanjing210007China The Army Artillery and Defense Academy of PLA Nanjing210007China PLA University of Foreign Language Luoyang471000China

The object detectors can precisely detect the camouflaged object beyond human *** investigations reveal that the CNNs-based(Convolution Neural Networks)detectors are vulnerable to adversarial *** works can fool detectors by crafting the adversarial camouflage attached to the object,leading to wrong *** is hard for military operations to utilize the existing adversarial camouflage due to its conspicuous *** by this,this paper proposes the Dual Attribute Adversarial Camouflage(DAAC)for evading the detection by both detectors and *** DAAC includes two steps:(1)Extracting features from a specific type of scene to generate individual soldier digital camouflage;(2)Attaching the adversarial patch with scene features constraint to the individual soldier digital camouflage to generate the adversarial attribute of *** visual effects of the individual soldier digital camouflage and the adversarial patch will be improved after integrating with the scene *** results show that objects camouflaged by DAAC are well integrated with background and achieve visual concealment while remaining effective in fooling object detectors,thus evading the detections by both detectors and humans in the digital *** work can serve as the reference for crafting the adversarial camouflage in the physical world.

关键词： Adversarial camouflage Digital camouflage generation Visual concealment Object detection Adversarial patch

Rail Detection Based on LSD and the Least Square Curve Fitting

在线全文

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2021年第1期18卷 85-95页

作者： yun-Shui zheng Yan-Wei Jin Yu Dong College of Automation and Electrical Engineering Lanzhou Jiaotong UniversityLanzhou 730070China Automation Research Institute Lanzhou Jiaotong UniversityLanzhou 730070China

It is necessary to rely on the rail gauge to determine whether the object beside the track will affect train operation safety or not.A convenient and fast method based on line segment detector(LSD)and the least square curve fitting to identify the rail in the image is proposed in this *** image in front of the train can be obtained through the camera *** preprocessing,it will be divided equally along the longitudinal *** the characteristics of the LSD algorithm,the edges are approximated into multiple line *** screening the terminals of the line segments,it can generate the mathematical model of the rail in the image based on the least *** show that the algorithm in this paper can fit the rail curve accurately and has good applicability and robustness.

关键词： Rail inspection line segment detector(LSD)algorithm the least square curve fitting foreign object detection

Hepatitis B virus infection modeling using multi-cellular organoids derived from human induced pluripotent stem cells

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2021年第29期27卷 4784-4801页

作者： Di Cao Jian-yun Ge yun Wang Tatsuya Oda yun-Wen zheng Institute of Regenerative Medicine and Affiliated Hospital of Jiangsu University Jiangsu UniversityZhenjiang 212001Jiangsu ProvinceChina Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Faculty of MedicineUniversity of TsukubaTsukuba 305-8575IbarakiJapan Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine and School of Biotechnology and Heath SciencesWuyi UniversityJiangmen 529020Guangdong ProvinceChina School of Medicine Yokohama City UniversityYokohama 234-0006KanagawaJapan

Chronic infection with hepatitis B virus(HBV)remains a global health concern despite the availability of *** date,the development of effective treatments has been severely hampered by the lack of reliable,reproducible,and scalable in vitro modeling systems that precisely recapitulate the virus life cycle and represent virus-host *** the progressive understanding of liver organogenesis mechanisms,the development of human induced pluripotent stem cell(iPSC)-derived hepatic sources and stromal cellular compositions provides novel strategies for personalized modeling and treatment of liver ***,advancements in three-dimensional culture of self-organized liver-like organoids considerably promote in vitro modeling of intact human liver tissue,in terms of both hepatic function and other physiological *** with our experiences in the investigation of HBV infections using liver organoids,we have summarized the advances in modeling reported thus far and discussed the limitations and ongoing challenges in the application of liver organoids,particularly those with multi-cellular components derived from human *** review provides general guidelines for establishing clinical-grade iPSC-derived multi-cellular organoids in modeling personalized hepatitis virus infection and other liver diseases,as well as drug testing and transplantation therapy.

关键词： Hepatitis B virus Induced pluripotent stem cells Liver organoid Multicellular organoid Modeling Transplantable

Synthesis and Crystal Structure of a Three-dimensional (3D) Complex Mn(H_2O)_2(HNic)_2 (HNic=2-Hydroxynicotinic Acid)

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2006年第5期25卷 572-576页

作者： LI Yu-Mei CHE yun-Xia zheng Ji-Min Department of Chemistry Nankai University Tianjin 300071 China

The title complex Mn（H2O）2（HNic）2 （C22H12MnN2O8, Mr = 367.18） crystallizes in monoclinic, space group P21/c with a = 7.5735（8）, b = 12.5295（13）, c = 7.6466（8）A.β = 101.2790（10）°, Z = 2, V= 711.59（13） A^3, D, = 1.714 g/cm^3,μ（MoKa） = 0.974 mm^-1, F（000） = 374, R1 （1255 observed reflections （Ⅰ 〉 2σ（Ⅰ）） = 0.0250） and wR2 = 0.0662 （all data）. In this paper, we report the complexation of Mn（Ⅱ） by the bidentate ligand 2-hydroxynicotinic acid （HNic）. In the crystal the Mn（Ⅱ） ion exhibits a deformed octahedron structure. The title complex Mn（H2O）2（HNic）2 has a three-dimensional （3D） network structure extended by hydrogen bonds, which are formed by two typical eight-membered hydrogen-bonded rings.

关键词： complex crystal structure three-dimensional network