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Changes in a cerebellar peduncle lesion in a patient with Dandy-Walker malformation A diffusion tensor imaging study

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Neural Regeneration Research 2013年第5期8卷 474-478页

作者： Ah Young Lee Sung Ho Jang Sang Seok Yeo Ensil Lee yun woo cho Su Min Son Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Pediatrics College of Medicine Yeungnam University

We report a patient with severe ataxia due to Dandy-Walker malformation, who showed functional recovery over 10 months corresponding to a change in a cerebellar peduncle lesion. A 20-month-old female patient who was diagnosed with Dandy-Walker syndrome and six age- and sex-matched healthy control subjects were enrolled. The superior cerebellar peduncle, the middle cerebellar peduncle, and the inferior cerebellar peduncle were evaluated using fractional anisotropy and the apparent diffusion coefficient. The patients＇ functional ambulation category was 0 at the initial visit, but improved to 2 at the follow-up evaluation, and Berg＇s balance scale score also improved from 0 to 7. Initial diffusion tensor tractography revealed that the inferior cerebellar peduncle was not detected, that the fractional anisotropy of the superior cerebellar peduncle and middle cerebellar peduncle decreased by two standard deviations below, and that the apparent diffusion coefficient increased by two standard deviations over normal control values. However, on follow-up diffusion tensor tractography, both inferior cerebellar peduncles could be detected, and the fractional anisotropy of superior cerebellar peduncle increased to within two standard deviations of normal controls. The functional improvement in this patient appeared to correspond to changes in these cerebellar peduncles. We believe that evaluating cerebellar peduncles using diffusion tensor imaging is useful in cases when a cerebellar peduncle lesion is suspected.

关键词： neural regeneration neuroimaging Dandy-Walker malformation cerebellar peduncle ataxia cerebral palsy functional ambulation category Berg's balance scale fractional anisotropy apparent diffusion coefficient diffusion tensor tractography diffusion tensor imaging grants-supported paper photographs-containing paper neuroregeneration

Therapeutic benefit of repetitive transcranial magnetic stimulation for severe mirror movements A case report

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Neural Regeneration Research 2013年第6期8卷 569-574页

作者： Han Sun Kim Sung Ho Jang Zee-Ihn Lee Mi Young Lee yun woo cho Migyoung Kweon Su Min Son Department of Physical Medicine and Rehabilitation College of MedicineYeungnam University Department of Pediatrics College of MedicineYeungnam University Department of Physical Medicine and Rehabilitation Daegu Fatima Hospital Department of Physical therapy College of Health and TherapyDaegu Haany University

Congenital mirror movements retard typical hand functions, but no definite therapeutic modality is available to treat such movements. We report an 8-year-old boy with severe mirror movements of both hands. His mirror movements were assessed using the woods and Teuber grading scale and his fine motor skills were also evaluated by the Purdue Pegboard Test. A 2-week regimen of repetitive transcranial magnetic stimulation produced markedly diminished mirror movement symptoms and increased the fine motor skills of both hands. Two weeks after the completion of the regimen, mirror movement grades had improved from grade 4 to 1 in both hands and the Purdue Pegboard Test results of the right and left hands also improved from 12 to 14 or 13. These improvements were maintained for 1 month after the 2-week repetitive transcranial magnetic stimulation regimen. After 18 months, the mirror movement grade was maintained and the Purdue Pegboard test score had improved to 15 for the right hand while the left hand score was maintained at 13. This occurred without any additional repetitive transcranial magnetic stimulation or other treatment. These findings suggest that repetitive transcranial magnetic stimulation for this patient had a therapeutic and long-term effect on mirror movements.

关键词： neural regeneration neurorehabilitation clinical practice mirror movements Purdue Pegboard test hand transcranial magnetic stimulation hand function cortex suppression corticospinal tract grants-supported paper neuroregeneration

The Effect of Plasma Surface Treatment on a Porous Green Ceramic Film with Polymeric Binder Materials

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Plasma Science and Technology 2013年第6期15卷 521-527页

作者： Jeong woo yun School of Applied Chemical Engineering Chonnam National University

To reduce time and energy during thermal binder removal in the ceramic process, plasma surface treatment was applied before the lamination *** adhesion strength in the lamination films was enhanced by oxidative plasma treatment of the porous green ceramic film with polymeric binding *** oxygen plasma characteristics were investigated through experimental parameters and weight loss *** experimental results revealed the need for parameter analysis,including gas material,process time,flow rate,and discharge power,and supported a mechanism consisting of competing ablation and deposition *** weight loss analysis was conducted for cyclic plasma treatment rather than continuous plasma treatment for the purpose of improving the film’s permeability by suppressing deposition of the ablated *** cyclic plasma treatment improved the permeability compared to the continuous plasma treatment.

关键词： plasma surface treatment oxidative plasma green ceramic film ablation deposition

High-index-contrast photonic structures:a versatile platform for photon manipulation

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Light(Science & Applications) 2022年第11期11卷 2617-2632页

作者： Young-Bin Kim Jin-woo cho yun-Jo Lee Dukkyu Bae Sun-Kyung Kim Department of Applied Physics Kyung Hee UniversityYonginGyeonggido 17104Republic of Korea Hexa Solution Co. LtdSuwonGyeonggi-do 16229Republic of Korea

In optics,the refractive index of a material and its spatial distribution determine the characteristics of light ***,exploring both low-and high-index materials/structures is an important consideration in this *** cavities,which are defined as low-index bases,exhibit a variety of unusual or even unexplored optical characteristics and are used in numerous functionalities including diffraction gratings,localised optical antennas and low-loss *** this report,we discuss the fabrication of hollow cavities of various sizes(O.2-5μm in diameter)that are supported by conformal dielectric/metal shells,as well as their specific applications in the ultraviolet(photodetectors),visible(light-emitting diodes,solar cells and metalenses),near-infrared(thermophotovoltaics)and mid-infrared(radiative coolers)*** findings demonstrate that hollow cavities tailored to specific spectra and applications can serve as versatile optical platforms to address the limitations of current optoelectronic ***,hollow cavity embedded structures are highly elastic and can minimise the thermal stress caused by high *** such,future applications will likely include high-temperature devices such as thermophotovoltaics and concentrator photovoltaics.

关键词： versatile index ultraviolet

Calcium and Calmodulin-Mediated Regulation of Gene Expression in Plants

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Molecular Plant 2009年第1期2卷 13-21页

作者： Min Chul Kim woo Sik Chung Dae-Jin yun Moo Je cho Division of Applied Life Science (BK21 Program) Plant Molecular Biology and Biotechnology Research Center and Environmental Biotechnology National Core Research Center Gyeongsang National University Jinju 660-701 Korea

Sessile plants have developed a very delicate system to sense diverse kinds of endogenous developmental cues and exogenous environmental stimuli by using a simple Ca^2＋ ion. Calmodulin （CAM） is the predominant Ca^2＋ sensor and plays a crucial role in decoding the Ca^2＋ signatures into proper cellular responses in various cellular compartments in eukaryotes. A growing body of evidence points to the importance of Ca^2＋ and CaM in the regulation of the transcriptional process during plant responses to endogenous and exogenous stimuli. Here, we review recent progress in the identification of transcriptional regulators modulated by Ca^2＋ and CaM and in the assessment of their functional significance during plant signal transduction in response to biotic and abiotic stresses and developmental cues.

关键词： Abiotic/environmental stress calcium signaling/transport gene expression.

Anesthetics management of a renal angiomyolipoma using pulse pressure variation and non-invasive cardiac output monitoring: A case report

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World Journal of Clinical Cases 2022年第24期10卷 8656-8661页

作者： woo Jae Jeon woo Jong Shin Young Joon Yoon Chan woo Park Jae Hang Shim Sang yun cho Department of Anesthesiolgy and Pain Medicine Hanyang University Guri HospitalGuri-si 471-701Gyeonggi-doSouth Korea

BACKGROUND Hypovolemic shock can lead to life-threatening organ dysfunction,and adequate fluid administration is a fundamental ***,parameters such as vital signs,central venous pressure,and urine output have been used to estimate intravascular ***,pulse pressure variation(PPV)and non-invasive cardiac monitoring devices have been *** this case report,we introduce a patient with massive active bleeding from giant renal angiomyolipoma(AML).During emergent nephrectomy,we used non-invasive cardiac monitoring with CSN-1901(Nihon Kohden,Tokyo,Japan)and PPV to evaluate the patient's intravascular volume status to achieve optimal fluid *** SUMMARY A 30-year-old male patient with giant AML with active bleeding was referred to the emergency room complaining of severe abdominal pain and spontaneous abdominal *** was diagnosed by computed tomography,and emergent nephrectomy was *** bleeding was expected so we decided to use non-invasive cardiac monitoring and PPV to assist fluid therapy because they are relatively easy and fast compared to invasive cardiac *** the surgery,6000 mL of estimated blood loss *** with the patient's vital signs and laboratory results,we monitored cardiac output,cardiac output,stroke volume,stroke volume index with a non-invasive cardiac monitoring device,and PPV using an intra-arterial catheter to evaluate intravascular volume status of the patient to compensate for massive *** In addition to traditional parameters,non-invasive cardiac monitoring and PPV are useful methods to evaluate patient's intravascular volume status and provideguidance for intraoperative management of hypovolemic shock patients.

关键词： Renal angiomyolipoma Pulse pressure variation Cardiac output Case report

Unilateral pulmonary hemorrhage caused by negative pressure pulmonary edema:A case report

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World Journal of Clinical Cases 2021年第6期9卷 1408-1415页

作者： Hyung Joon Park Seung Ho Park Un Tak woo Sang yun cho woo Jae Jeon woo Jong Shin Department of Anesthesia and Pain Medicine Hanyang UniversityGuri HospitalGuri 11923Gyeonggi-doSouth Korea

BACKGROUND Unilateral pulmonary hemorrhage is typically reported in young and healthy men with upper respiratory tract obstruction during anesthesia in special *** pressure in the lungs is created,resulting in negative pressure pulmonary edema(NPPE).CASE SUMMARY A 78-year-old male patient diagnosed with spinal stenosis was admitted to receive a unilateral laminectomy with bilateral *** patient had been diagnosed with hypertension four years earlier and asthma more than 70 years *** experienced a unilateral alveolar hemorrhage associated with NPPE that occurred in a longstanding asthma patient who bit the intubated endotracheal tube for a short period during posture change at the end of *** diffuse alveolar hemorrhage accompanied by NPPE was caused in this case by airway obstruction in an older patient with asthma without known risk factors,anesthesiologists should be careful not to induce airway irritation during anesthesia awakening in asthma *** Because diffuse alveolar hemorrhage accompanied by NPPE can occur,anesthesiologists should take care not to induce airway irritation.

关键词： Airway Anesthesia Asthma Hemorrhage Pulmonary edema Case report Surgery

Beneficial Effect of Berberis amurensis Rupr. on Penile Erection

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Chinese Journal of Integrative Medicine 2018年第6期24卷 448-454页

作者： Rui Tan yun Jung Lee Kyung woo cho Dae Gill Kang Ho Sub Lee College of Oriental Medicine and Professional Graduate School of Oriental Medicine Wonkwang University Hanbang CardioRenal Syndrome Research Center Wonkwang University Brain Korea 21 Plus Team Professional Graduate School of Oriental MedicineWonkwang University

Objective： To investigate whether the methanol extract of Berberis amurensis Rupr. （BAR） augments penile erection using in vitro and in vivo experiments. Methods： The ex vivo study used corpus cavemosum strips prepared from adult male New Zealand White rabbits. In in vivo studies for intracavernous pressure （ICP）, blood pressure, mean arterial pressure （MAP）, and increase of peak ICP were continuously monitored during electrical stimulation of Sprague-Dawley rats. Results： Preconstricted with phenylephrine （PE） in isolated endothelium- intact rabbit corus cavernosum, BAR relaxed penile smooth muscle in a dose-dependent manner, which was inhibited by pretreatment with NG-nitro-L-arginine methyl ester （L-NAME）, a nitric oxide synthase inhibitor, and 1H-[1,2,4]-oxadiazole-[4,3-α]-quinoxalin-l-one, a soluble guanylyl cclase inhibitor. BAR significantly relaxed penile smooth muscles dose-dependently in ex vivo, and this was inhibited by pretreatment with L-NAME 1H-[1,2,4]- oxadiazole-[4,3-α ]-quinoxalin-l-one. BAR-induced relaxation was significantly attenuated by pretreatment with tetraethylammonium （TEA, P〈0.01）, a nonselective K＋ channel blocker, 4-aminopyridine （4-AP, P〈0.01）, a voltage-dependent K＋ channel blocker, and charybdotoxin （P〈0.01）, a large and intermediate conductance Ca2. sensitive-K＋ channel blocker, respectively. BAR induced an increase in peak ICP, ICP/MAP ratio and area under the curve dose dependently. Conclusion： BAR augments penile erection via the nitric oxide/cyclic guanosine monophosphate system and Ca2. sensitive-K＋（BK＋ and IK＋） channels in the corpus cavemosum.

关键词： penile erection Berberis amurensis Rupr. nitric oxide cyclic guanosine monophosphate K+ channel

Portable nano probe for micro/nano mechanical scratching and measuring

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 205-209页

作者： woo-Park JEONG Chang-choi SOO cho Hyun woo-Lee DEUG Department of Mechanical Design Engineering Chosun University Department of Nano Fusion Technology Pusan National University Department of Nano-mechatronics Engineering Pusan National University

A nano probe system which can measure precise contact force in mN scale was demonstrated. The nano probe micro parts or optical parts in nanometer range resolution and scratch was originally designed for on-machine measuring applications and one kind of contact type measuring probes was designed for miniaturized or microfactory system. It ideally should be of small size and able to measure surface topography in nanometer scale. A commercial capacitive displacement sensor was proposed. It was a new concept in nano probe systems which can measure the displacement of shaft driven by the variation of surface topography. The nano probe mainly consisted of three parts： a capacitive displacement sensor, a porous type air slide and a contact probe part with various tip radiuses. The porous type air slide assured the shaft slided smoothly with controllable normal force in mN scale and had high positioning accuracy. The probe part which was directly in contact with target surface, can be applied to micro/nanoscale scratching as well as the measurement of sample topography by a simple tip change.

关键词： nano probe displacement sensor air slide PCD tip