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Prognostic factors for recurrence of gastrointestinal bleeding due to Dieulafoy's lesion

World Journal of Gastroenterology 2012年第40期18卷 5734-5738页

作者： yuliana jamanca-poma Antonio Velasco-Guardado Concepción Piero-Pérez Renzo Calderón-Begazo Josue Umaa-Mejía Fernando Geijo-Martínez Antonio Rodríguez-Pérez Department of Digestive System University Hospital of Salamanca

AIM:To analyze the effectiveness of the endoscopic therapy and to identify prognostic factors for recurrent ***:Retrospective study of patients with gastrointestinal bleeding secondary to Dieulafoy's lesion(DL) from 2005 to *** analyzed the demographic characteristics of the patients,risk factors for gastrointestinal bleeding,endoscopic findings,characteristics of the endoscopic treatment,and the recurrence of *** included cases in which endoscopy described a lesion compatible with *** excluded patients who had potentially bleeding lesions such as angiodysplasia in other areas or had undergone other gastrointestinal endoscopic ***:Twenty-nine patients with DL were *** of them were men with an average age of 71.5 ***-five percent of the patients received antiaggregatory or anticoagulant *** most common location for DL was the stomach(51.7%).The main type of bleeding was oozing in 65.5% of *** 27.6% of cases,there was arterial(spurting) bleeding,and 6.9% of the patients presented with an adherent clot.A single endoscopic treatment was applied to nine patients(31%);eight of them with adrenaline and one with argon,while 69% of the patients received combined *** patients(20.7%) presented with recurrent bleeding at a median of 4 d after endoscopy(interquartile range = 97.75).Within these six patients,the new endoscopic treatment obtained a therapeutic success of 100%.The presence of arterial bleeding at endoscopy was associated with a higher recurrence rate for bleeding(50% vs 33.3% for other type of bleeding) [P = 0.024,odds ratio(OR) = 8.5,95% CI = 1.13-63.87].The use of combined endoscopic treatment prevented the recurrence of bleeding(10% vs 44.4% of single treatment)(P = 0.034,OR = 0.14,95% CI = 0.19-0.99).CONCLUSION:Endoscopic treatment of DL is safe and *** monotherapy and arterial(spurting) bleeding are associated with a high rate of bleeding recurrence.

关键词：肠道出血复发率胃肠道病变预后联合治疗危险因素发育不良

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Development of an analytical method based on solid-phase extraction and LC-MS/MS for the monitoring of current-use pesticides and their metabolites in human urine

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Journal of Environmental Sciences 2022年第1期34卷 153-163页

作者： Beibei Gao Giulia poma Govindan Malarvannan Catalina Dumitrascu Michiel Bastiaensen Minghua Wang Adrian Covaci Toxicological Centre University of AntwerpWilrijk 2610Belgium Department of Pesticide Science College of Plant ProtectionState and Local Joint Engineering Research Center of Green Pesticide Invention and ApplicationNanjing Agricultural UniversityNanjing 210095China

Pyrethroids,organophosphorus pesticides and fipronil have been listed as priority chemicals in human biomonitoring studies because of their wide use and potential health effects in *** determination of 13 pesticides,including pyrethroids(deltamethrin,cypermethrin,permethrin,cyfluthrin,bifenthrin),organophosphorus(chlorpyrifos,chlorpyrifosmethyl,and malathion),fipronil,neonicotinoids(imidacloprid,acetamiprid and thiacloprid)and triazole(prothioconazole),together with 13 corresponding metabolites in human urine samples was achieved by solid-phase extraction and analysis by liquid chromatography coupled to tandem mass *** targeted compounds,except malathion dicarboxylic acid,were measured with a mean within-accuracy(n=5)of 71%–114%(RSD:1%–14%)and between-run(n=15)accuracy of 80%–118%(RSD:2%–14%).Limits of quantitation of the targeted analytes ranged from 0.1 to 16 pg/m *** detection result of urine samples from 25 volunteers indicated that the detection frequencies of 3,5,6-trichloro-2-pyridinol(median:448 pg/m L),6-chloropyridine-3-carboxylic acid(median:193 pg/m L),2-methyl-3-phenylbenzoic acid(median:181 pg/m L),3-phenoxybenzoic acid(median:99 pg/m L),2-isopropyl-6-methyl-4-pyrimidinol(median:77 pg/m L),cyfluthrin(median:59 pg/m L),cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid(cis-DCCA,median:53 pg/m L),trans-DCCA(median:25 pg/m L),prothioconazole(median:21 pg/m L),imidacloprid(median:7 pg/m L),and prothioconazole-desthio(median:1 pg/m L)were>50%.The obtained results show that the validated method is suitable for the human biomonitoring of these currentuse pesticides and their metabolites.

关键词： Pyrethroids Organophosphorus Fipronil Neonicotinoids Urine Biomonitoring

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Multifactorial nature of hepatocellular carcinoma drug resistance: Could plant polyphenols be helpful?

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World Journal of Gastroenterology 2007年第14期13卷 2037-2043页

作者： Natale D'Alessandro Paola poma Giuseppe Montalto Department of Pharmacological Sciences University of Palermo Italy Department of Clinical Medicine University of Palermo PalermoItaly

主要肝细胞癌(HCC ) 是导致高死亡并且最经常展出差的回答介绍药治疗的一个相当经常的肿瘤。清楚地，这恶意的生物的底的彻底的理解可能为它的治疗建议新策略。这里，我们检验证据两“药理学”机制(例如药 transporter 或 detoxificati... 详细信息

主要肝细胞癌(HCC ) 是导致高死亡并且最经常展出差的回答介绍药治疗的一个相当经常的肿瘤。清楚地，这恶意的生物的底的彻底的理解可能为它的治疗建议新策略。这里，我们检验证据两“药理学”机制(例如药 transporter 或 detoxification 酶在表示上) 并且在另外的关键因素的改变，包括国际机场(Apoptosis 蛋白质禁止) ，在房间幸存和增长的改进包含了可以决定 HCC 的治疗学的抵抗；我们也在抄写因素的激活的过程加重可能的角色，象 NF-kappaB 一样，能够同时起来调整讨论的机制。在这个基础上，我们最后评论象植物多酚一样的自然多指向的 antitumoral 代理人的可能的使用在 HCC 完成促进感受性到处理。

关键词：肝细胞癌耐药性多因子属性植物多酚

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Palpebral Reconstruction in a Secondary Ophthalmology Center in Mali: About a Case

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Surgical Science 2023年第2期14卷 97-103页

作者： Dembélé Adama Sidibe Moro Sidibe Oumar Dembele Ahmadou poma Hachimi Amadou Abdoulaye Konaté Oumar Diallo Djonny Jonas Dembele Mamadou Adama Togo Kadiatou Ba Koita Abdoulaye Nouhoum Coulibaly Cheick Fantamady Tounkara Nouhoum Touré Napo Abdoulaye Régional Hospital of Sikasso Sikasso Mali Alliance for the Development of Community Ophthalmology (ADOC) Bamako Mali Center Médical Jean Marie Cissé Sikasso Mali

Introduction: Significant trauma to the periocular region can seriously damage ocular structures and their adnexa. The eyelids can be damaged during these traumas. The most frequent lesions are lacerations, the surgical treatment of which is generally simple. In some cases, there are complex traumas where there is a loss of tissue, which is difficult to treat. We report the case of a 26-year-old young man, farmer with no medical and surgical history, referred by the odontostomatology and maxillofacial surgery department for burns to the left hemi face by the exhaust pipe of his motorbike which occurred following a public road accident (AVP). Observation: A 26-year-old young man with no medical-surgical history, visual acuity was 5/10 with good mobility of the globe. In collaboration with the maxillofacial surgeon, a graft of the hemi face was performed using a flap from the inner side of the thigh first. In the second time we carried out a recovery by a flap which consisted in taking a supra-superciliary flap and suturing it at the level of the palpebral edges which, in spite of a fragile vitality of the tissues. Conclusion: The reconstruction of the eyelid is a real problem in our service because of the technical platform and the availability of consumables, which limits us in the choice of the operating technique.

关键词： Road Accident Hemi-Face Burn Eyelid Reconstruction

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Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature

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World Journal of Gastroenterology 2006年第32期12卷 5234-5236页

作者： Chiara Riviello Ilaria Tanini Greta Cipriani Pietro Pantaleo Carlo Nozzoli Alberto poma Viligiardi Riccardo Andrea Valeri Second Division of General and Vascular Surgery Careggi Hospital FlorenceItaly Department of Internal Medicine Oncologic Day-Hospital University of Florence Italy Second Division of Internal Medicine Careggi Hospital FlorenceItaly

肾的房间癌(RCC ) 是最普通的肾的肿瘤，为所有恶意的 2%-3% 的财务。尽管 RCC 被知道造血地传播，到胃的孤立的 RCC 转移是一个稀罕事件。在这篇文章，我们描述 RCC 的胃的复发 10 年以前与切除术和 interleukin-2 (IL-2 ) 对待的以后... 详细信息

肾的房间癌(RCC ) 是最普通的肾的肿瘤，为所有恶意的 2%-3% 的财务。尽管 RCC 被知道造血地传播，到胃的孤立的 RCC 转移是一个稀罕事件。在这篇文章，我们描述 RCC 的胃的复发 10 年以前与切除术和 interleukin-2 (IL-2 ) 对待的以后开发了 RCC 和 1 年的胰腺的复发的一个病人的临床的功课。积累的证据显示胰和胃的那变形参与应该与 RCC 的历史在任何病人被怀疑在 RCC 切除术和免疫疗法以后与胃肠的症状介绍甚至 10 年。

关键词：胃疾病胰腺疾病肾细胞癌免疫治疗

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Increasing Efficiency through Tokenization of Digital Assets in an Exporting Company 4.0

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Journal of Sustainable Business and Economics 2022年第1期5卷 29-42页

作者： JoséAntonio Trigueros Pina Napoleón B.Alegre poma Miguel Hernandez University Spain Universidad Internacional Iberoamericana-UNINI México Costa Rica

Digital assets have been introduced to the global market as one of the innovations with the *** though their impact on the traditional economy is impossible to *** tokens(ST)are the ones that stand out due to the preference they have from producers and *** former obtains financial resources efficiently for their specific *** the latter look for STs in global digital platforms of trust and *** are regulated by public securities sales *** research proposes a method under the fuzzy logic theory and its applied *** highlights the use of the triangular fuzzy numbers,the Fuzzy Delfi,Expertons,Hamming Distance,and the fuzzy inference system(FIS).The benefits and limitations of the proposal were highlighted when the proposal was used in an agro-export *** route or algorithm of the value system to be followed in the execution of the investments stands ***,the research fulfills its objective and is very useful for small and medium export 4.0 *** they are eager to obtain cash flow to improve their technical efficiency and to be able to export their artifacts to global *** is to say,the producer of goods can obtain an unprecedented benefit in an agile and efficient way in the context of Industry 4.0.

关键词： STO ST SME Industry 4.0 Asset tokenization

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Tuning the Defects in AgO Nanoparticles/Graphene Bilayers System by Laser Power Density

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Journal of Physical Science and Application 2017年第1期7卷 21-28页

作者： H. Ferreira M. Briones M. Camilo G. poma Maria Quintana A. Champi Centro de Ciencias Naturais e Humanas Universidade Federal do ABC 09210-170 Santo Andre SP Brazil Universidad Nacional de Ingenierla P.O. Box 31-139 Av. Tupac Amaru 210 Lima Peru

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苏联东萨阳斯克碱性地区的碳酸盐岩

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陕西地质科技情报 1991年第1期16卷 65-66页

作者： poma.,UA 罗旭

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探索从FOLFOXIRI/贝伐珠单抗治疗获益的BRAF突变转移性结直肠癌患者的临床和基因表达标志物:TRIBE2研究的亚组分析

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结直肠肛门外科 2021年第4期27卷 396-397页

作者：何婉李绍堂 MORETTO R GIORDANO M poma A M 深圳市人民医院肿瘤内科广东深圳518020 温州医科大学附属第一医院结直肠外科浙江温州325000 不详

背景:TRIBE2研究的最新数据未能表明前期应用FOLFOX⁃IRI/贝伐珠单抗对BRAF突变的转移性结直肠癌(mCRC)患者有更多的益处,如先前在TRIBE研究中报告所述。病例和方法:对TRIBE2研究中存在BRAF突变的mCRC患者的临床特征和基因表达特征进行... 详细信息

背景:TRIBE2研究的最新数据未能表明前期应用FOLFOX⁃IRI/贝伐珠单抗对BRAF突变的转移性结直肠癌(mCRC)患者有更多的益处,如先前在TRIBE研究中报告所述。病例和方法:对TRIBE2研究中存在BRAF突变的mCRC患者的临床特征和基因表达特征进行了评估,目的是识别可能从前期强化化疗中获益的患者。

关键词：贝伐珠单抗转移性结直肠癌亚组分析基因表达 FOLFOX 标志物临床特征新数据

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Congenital Gangrene in a Premature Newborn: A Case Report

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Open Journal of Pediatrics 2021年第3期11卷 393-397页

作者： Assetou Cissouma Mamadou B. Coulibaly Djibril Kassogué Hachimi A. poma Moussa Diassana Bathio Traoré Aly Diallo Layes Touré Ternan Traoré Moussa Kanté Abdoulaye Kissima-Traoré Pediatric Service Sikasso Hospital Sikasso Mali Pediatric Surgery Service Sikasso Hospital Sikasso Mali Pediatric Service Timbuktu Hospital Timbuktu Mali Surgery General Service Sikasso Hospital Sikasso Mali Orthopedic and Trauma Surgery Service Sikasso Hospital Sikasso Mali Anesthesia and Intensive Care Service Sikasso Hospital Sikasso Mali Cardiology Service Sikasso Hospital Sikasso Mali

Introduction: Congenital limb gangrene is a rare pathology. In the majority of cases, no cause is identified and its treatment is not codified. Observation: 29-week premature newborn, female from poorly followed twin pregnancy. Clinical examination at admission found an unstable neonate, the presence of necrosis of the left hand and forearm well limited, with absent humeral pulse and absence of hand movement. Surgical treatment was scheduled for amputation of the limb after the agreement of the parents whose postoperative follow-ups were simple. Conclusion: Congenital gangrene remains a rare entity in neonatology.

关键词： Gangrene Upper Limb Newborn Prematurity

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