检索结果-南通市图书馆

Open Journal of Endocrine and Metabolic Diseases 2013年第2期3卷 10-13页

作者： Galina A. Frelikh Elena A. Yanovskaya Natalia Yu. Polomeeva Maxim S. Timofeev Vladimir A. Slepichev Olga S. Bryushinina yulia G. Zyuz’kova Roman V. Gurto Alexander S. Vasil’ev Elena V. Semiglazova Vladimir V. Udut Laboratory of Physiology Molecular and Clinical Pharmacology Federal Governmental Budgetary Organization “Research Institute of Pharmacology” Siberian Branch of the Russian Academy of Medical Sciences Tomsk Russia

In the work, we offer a brief report by research results demonstrating correlations between energy status of peripheral blood lymphocytes and functional state of vital tissues mitochondria. Basing on our preliminary data, showing correlations between succinate dehydrogenase (SDH) activity in peripheral blood lymphocytes and speed or duration of pyridine nucleotides reduction in mitochondria of rat brain and liver tissues, we propose an idea of using cytobiochemical method of SDH estimation in peripheral blood lymphocytes for evaluation of tissue mitochondria status. The method could be successfully used in clinical practice for early revealing of energy metabolism disturbances that allows preventing disease development and optimizing the diseases therapy.

关键词： Mitochondria Energy Metabolism Lymphocyte Succinate Dehydrogenase Cytobiochemical

Solution of Self-similar Equations of the k-ε Model in the Shear Turbulent Mixing Problem and Its Numerical Simulation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Physical Science and Application 2015年第6期5卷 377-395页

作者： Vyacheslav P. Statsenko yulia V. Tret'yachenko Yury V. Yanilkin Russian Federal Nuclear Centre VNIIEF Sarov 607200 Russia

Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第3期7卷 856-868页

作者： Qi Zhang Bridget Riley-Gillis Lina Han Yanan Jia Alessia Lodi Haijiao Zhang Saravanan Ganesan Rongqing Pan Sergej N.Konoplev Shannon R.Sweeney Jeremy A.Ryan yulia Jitkova Kenneth Dunner Jr Shaun E.Grosskurth Priyanka Vijay Sujana Ghosh Charles Lu Wencai Ma Stephen Kurtz Vivian R.Ruvolo Helen Ma Connie CWeng Cassandra LRamage Natalia Baran Ce Shi Tianyu Cai Richard Eric Davis Venkata L.Battula Yingchang Mi Jing Wang Courtney D.DiNardo Michael Andreeff Jeffery W.Tyner Aaron Schimmer Anthony Letai Rose Ann Padua Carlos E.Bueso-Ramos Stefano Tiziani Joel Leverson Relja Popovic Marina Konopleva Department of Leukemia The University of Texas MD Anderson Cancer CenterHoustonTXUSA AbbVie Inc. North ChicagoILUSA Institute of Hematology Chinese Academy of Medical Sciences&Peking Union Medical CollegeTianjinChina Department of Nutritional Sciences Department of PediatricsDepartment of OncologyDell Medical SchoolThe University of Texas at AustinAustinTX 78712USA Department of Cell Developmental&Cancer BiologyDivision of Hematology&Medical OncologyKnight Cancer InstituteOregon Health&Science UniversityPortlandORUSA Universite de Paris Institut de la Recherche Saint-Louis(IRSL)Inserm Unit 1131ParisFrance Dana-Farber Cancer Institute BostonMAUSA Department of Hematopathology The University of Texas MD Anderson Cancer CenterHoustonTXUSA Princess Margaret Cancer Center TorontoONCanada High Resolution Electron Microscopy Facility The University of Texas MD Anderson Cancer CenterHoustonTXUSA Department of Bioinformatics&Computational Biology The University of Texas MD Anderson Cancer CenterHoustonTXUSA Department of Hematology The First Hospital Affiliated Harbin Medical UniversityHarbinChina Department of Lymphoma&Myeloma Research The University of Texas MD Anderson Cancer CenterHoustonTXUSA

Despite high initial response rates,acute myeloid leukemia(AML)treated with the BCL-2-selective inhibitor venetoclax(VEN)alone or in combinations commonly acquires *** performed gene/protein expression,metabolomic and methylation analyses of isogenic AML cell lines sensitive or resistant to VEN,and identified the activation of RAS/MAPK pathway,leading to increased stability and higher levels of MCL-1 protein,as a major acquired mechanism of VEN resistance.

关键词： acute myeloid acquired

Evaluation of cancer treatment in the abdomen: Trends and advances

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Radiology 2013年第3期5卷 126-142页

作者： Silanath Peungjesada Hubert H Chuang Srinivasa R Prasad Haesun Choi Evelyne M Loyer yulia Bronstein Department of Diagnostic Radiology University of Texas MD Anderson Cancer Center Department of Nuclear Medicine University of Texas MD Anderson Cancer Center Virtual Radiologic 11995 Singletree Ln Suite 500 Eden Prairie MN 55344 United States

Response evaluation in Oncology has relied primarily on change in tumor size. Inconsistent results in the prediction of clinical outcome when size based criteria are used and the increasing role of targeted and locoregional therapies have led to the development of new methods of response evaluation that are unrelated to change in tumor size. The goals of this review are to expose briefly the size based criteria and to present the non-size based approaches that are currently applicable in the clinical setting. Other paths that are still being explored are not discussed in details.

关键词： Evaluation Cancer treatment Abdomen

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

红色星球莫斯科阿尔法银行数字金融部办公室

室内设计与装修 2021年第9期 44-48页

作者： [俄罗斯]IND architects(设计) 夕阳(编译) Andrey Sidorov(设计) yulia Khapkina(设计) Marina Shirokova(设计) Ekaterina Vasilyeva(设计) Natalia Buravkova(设计) Gzogyan Ruben(设计) Timur Urusov(设计) Dmitry Khomyakov(设计) Alexey Zarodov(摄影) IND architects

本案是阿尔法银行(Alfa-Bank)数字金融部位于莫斯科的新办公空间。承担该项目的IND architects设计团队在构思整体设计理念时,恰逢科技与太空狂人伊隆·马斯克(Elon Musk)正在测试一架飞往火星的航天器的原型机。因此,火星成了此次设计... 详细信息

本案是阿尔法银行(Alfa-Bank)数字金融部位于莫斯科的新办公空间。承担该项目的IND architects设计团队在构思整体设计理念时,恰逢科技与太空狂人伊隆·马斯克(Elon Musk)正在测试一架飞往火星的航天器的原型机。因此,火星成了此次设计的灵感来源,火星红作为主导色以不同的形态出现在空间内,成为当仁不让的专属标识。

关键词：数字金融阿尔法办公空间灵感来源设计团队银行设计理念莫斯科

Mesoporous Alumina in an AI2O3/Al Cermet Prepared from Powdered Aluminum

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

材料科学与工程（中英文版） 2011年第3期5卷 281-292页

作者： Tikhov Serguei Khabibulin Djalil Lapina Olga Salanov Aleksey Bespalko yulia Sadykov Vladislav Ratko Anatoly Kouznetsova Tatyana Romanenkov Vladimir Eremenko Svetlana Department of Heterogeneous Catalysis Boreskov Institute of Catalysis SD RAS 630090 Lavrentieva St. 5 Russia Department of Natural Sciences Novosibirsk State University Novosibirsk 630090 Russia Institute of General and Inorganic Chemistry NAS of Belarus Laboratory of Adsorption Minsk 220072 Belarus

Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第5期7卷 1860-1860页

作者： Qi Zhang Bridget Riley-Gillis Lina Han Yannan Jia Alessia Lodi Haijiao Zhang Saravanan Ganesan Rongqing Pan Sergej N.Konoplev Shannon R.Sweeney Jeremy A.Ryan yulia Jitkova Kenneth Dunner Jr Shaun E.Grosskurth Priyanka Vijay Sujana Ghosh Charles Lu Wencai Ma Stephen Kurtz Vivian R.Ruvolo Helen Ma Connie C.Weng Cassandra L.Ramage Natalia Baran Ce Shi Tianyu Cai Richard Eric Davis Venkata L.Battula Yingchang Mi Jing Wang Courtney D.DiNardo Michael Andreeff Jeffery W.Tyner Aaron Schimmer Anthony Letai Rose Ann Padua Carlos E.Bueso-Ramos Stefano Tiziani Joel Leverson Relja Popovic Marina Konopleva Department of Leukemia The University of Texas MD Anderson Cancer Center Houston TX USA Institute of Hematology Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin China Department of Hematology The First Hospital Affiliated Harbin Medical University Harbin China AbbVie Inc. North Chicago IL USA Department of Nutritional Sciences Department of Pediatrics Department of Oncology Dell Medical School The University of Texas at Austin Austin TX 78712 USA Department of Cell Developmental & Cancer Biology Division of Hematology & Medical Oncology Knight Cancer Institute Oregon Health & Science University Portland OR USA Université de Paris Institut de la Recherche Saint-Louis (IRSL) Inserm Unit 1131 Paris France Dana-Farber Cancer Institute Boston MA USA Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston TX USA Princess Margaret Cancer Center Toronto ON Canada High Resolution Electron Microscopy Facility The University of Texas MD Anderson Cancer Center Houston TX USA Department of Bioinformatics & Computational Biology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Lymphoma & Myeloma Research The University of Texas MD Anderson Cancer Center Houston TX USA

Correction to:Signal Transduction and Targeted Therapy(2022)7:1–13,https://***/10.1038/s41392-021-00870-3 In the original version of this article,given name of 4th author Yannan Jia was incorrectly published as Yanan *** original article has been *** Access This article is licensed under a Creative Commons Attribution 4.0 International License,which permits use,sharing,adaptation,distribution and reproduction in any medium or format,as long as you give appropriate credit to the original author(s)and the source.

关键词： myeloid Therapy resistance