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三维空间中不同线索对物体深度感知的影响

光学学报 2019年第10期39卷 369-375页

作者：贺书芳繁桝博昭石川祐記子代彩红中国计量科学研究院光学与激光计量科学研究所北京100029 高知工科大学研究生院日本高知7828502 高知工科大学信息学院日本高知7828502

通过在虚拟三维空间中构建基于双目视差和运动像差的不同深度的柱形面,使被试者在三维空间中行走运动,采用心理物理学的固定值刺激法,获取被试者在不同观察距离下基于双目视差线索、运动像差线索,以及两种线索同时作用时的深度感知数据... 详细信息

通过在虚拟三维空间中构建基于双目视差和运动像差的不同深度的柱形面,使被试者在三维空间中行走运动,采用心理物理学的固定值刺激法,获取被试者在不同观察距离下基于双目视差线索、运动像差线索,以及两种线索同时作用时的深度感知数据,研究双目视差线索和运动像差线索对人眼深度感知的影响。结果表明:在不同的观察距离下,双目视差线索和运动像差线索对人眼的深度感知有不同的影响;在远距离观察条件下,运动像差线索对深度感知的权重比在近距离观察条件下大;而在近距离观察条件下,两种线索同时作用时对深度感知没有促进作用,并且运动像差线索对深度感知的作用较小。

关键词：视觉光学双目视差运动像差深度感知三维空间心理物理学实验

Primary Neuroendocrine Carcinoma Combined with Squamous Cell Carcinoma of the Soft Palate: A Case Report and Review of Literature

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Open Journal of Stomatology 2018年第3期8卷 90-99页

作者： Chatchaphan Udompatanakorn Naomi Yada Ayataka ishikawa Ikuya Miyamoto yukiko Sato Kou Matsuo Division of Oral Pathology Department of Health Promotion Kyushu Dental University Kitakyushu Japan Department of Pathology Saitama Cancer Center Saitama Japan Department of Oral and Maxillofacial Reconstructive Surgery School of Dentistry Iwate Medical University Morioka Japan Division of Pathology Cancer Institute Japanese Foundation for Cancer Research Tokyo Japan

Background: Neuroendocrine carcinomas (NECs) are rare neoplasms that widely occur in various organs. They are heterogeneous and vary from low to high grade malignant. NEC presenting with a squamous cell carcinoma (SCC) component is referred to as a composite tumor. Thus far, few cases of this composite tumor in the oral cavity have been reported in the literature;thus, the histogenesis remains unclear. ase Presentation: We encountered a rare case of a primary NEC combined with SCC, occurring at the soft palate in a 59-year-old man. A resected specimen of the tumor was composed of two components: NEC and SCC. The NEC area contained small round to oval atypical cells arranged in nests with a glandular-like-pattern, hyperchromatic molded nuclei, a high nuclear-to-cytoplasmic ratio, and a scant eosinophilic cytoplasm. The SCC area was composed of non-keratotic, dysplastic oval to spindle-shaped squamous cells with indistinct cell borders and large nuclei that were hyperchromatic and pleomorphic. Immunohistochemically, the tumor cells of the NEC component were positive for chromagranin A, synaptophysin, CD56, and p16, whereas those of the SCC component were positive for 34βE12, p63, and p16. Conclusion: In consideration of the morphological and immunohistochemical results, the final diagnosis was a primary NEC combined with SCC of the soft palate.

关键词： Oral Cavity Neuroendocrine Carcinoma Squamous Cell Carcinoma Combined Tumor

Machine-learning-assisted discovery of polymers with high thermal conductivity using a molecular design algorithm

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npj Computational Materials 2019年第1期5卷 569-579页

作者： Stephen Wu yukiko Kondo Masa-aki Kakimoto Bin Yang Hironao Yamada Isao Kuwajima Guillaume Lambard Kenta Hongo Yibin Xu Junichiro Shiomi Christoph Schick Junko Morikawa Ryo Yoshida The Institute of Statistical Mathematics Research Organization of Information and SystemsTachikawaTokyo 190-8562Japan The Graduate University for Advanced Studies TachikawaTokyo 190-8562Japan Center for Materials research by Information Integration(CMI2) Research and Services Division of Materials Data and Integrated System(MaDIS)National Institute for Materials Science(NIMS)TsukubaIbaraki 305-0047Japan Institute of Physics and Competence Centre CALOR University of Rostock18059 RostockGermany Japan Advanced Institute of Science and Technology NomiIshikawa 923-1292Japan PRESTO JSTKawaguchiSaitama 332-0012Japan The University of Tokyo Bunkyo-kuTokyo 113-8656Japan Tokyo Tech World Research Hub Initiative(WRHI) Tokyo Institute of TechnologyTokyo 226-8503Japan Tokyo Institute of Technology Meguro-kuTokyo 152-8550Japan

The use of machine learning in computational molecular design has great potential to accelerate the discovery of innovative ***,its practical benefits still remain unproven in real-world applications,particularly in polymer *** demonstrate the successful discovery of new polymers with high thermal conductivity,inspired by machine-learning-assisted polymer *** discovery was made by the interplay between machine intelligence trained on a substantially limited amount of polymeric properties data,expertise from laboratory synthesis and advanced technologies for thermophysical property *** a molecular design algorithm trained to recognize quantitative structure—property relationships with respect to thermal conductivity and other targeted polymeric properties,we identified thousands of promising hypothetical *** these candidates,three were selected for monomer synthesis and polymerization because of their synthetic accessibility and their potential for ease of processing in further *** synthesized polymers reached thermal conductivities of 0.18–0.41 W/mK,which are comparable to those of state-of-the-art polymers in non-composite thermo-plastics.

关键词： conductivity thermal property

Hemoglobin Level Stability after a Switch from Darbepoetin Alfa to Epoetin Beta Pegol for the Treatment of Renal Anemia in Hemodialysis Patients

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International Journal of Clinical Medicine 2015年第9期6卷 652-660页

作者： Sayaka Takahashi Yoshiko Tanaka Mari Takano Keiko Suzuki Mio Ueda yukiko Shimamoto Kosaku Nitta Department of Nephrology Shinjuku Ishikawa Clinic Tokyo Japan Department of Medicine Kidney Center Tokyo Women’s Medical University Tokyo Japan

Background: New erythropoiesis-stimulating agents (ESAs) with a longer half-life have been developed for the treatment of anemia as a complication of patients with end-stage renal disease. Objectives: The objective of the present study was to assess the hemoglobin (Hb) stability of a Japanese cohort of hemodialysis (HD) patients who were simultaneously switched from darbepoetin alfa (DA) to epoetin beta pegol (CERA). Methods: This was an observational, prospective study of HD patients 20 years of age or more who were switched from intravenous (IV) DA to IV CERA and continued on HD for at least 3 months. The dose was adjusted to maintain the Hb level to within 1.0 g/dl of the baseline value. Results: A total of 68 HD patients (75.0% male, median age 63.0 years) were enrolled. The patients’ mean Hb levels were 10.8 ± (0.6) g/dl at Month 0, 10.9 ± 0.7 at Month 1, 10.8 ± 0.7 at Month 2, and 10.9 ± 0.8 at Month 3, and the differences from the level at Month 0 were not significant. After the switch, the ESA dose decreased significantly (P P < 0.0001). Conclusion: Switching from DA to CERA was associated with approximate 89% reduction of the required dose in Japanese HD patients being treated with an ESA and showed a favorable impact on the treatment of renal anemia, including the need for less frequent injections and a reduction of the ESA dose.

关键词： Darbepoetin Alfa Epoetin Beta Pegol Hemoglobin ESA Resistance Hemodialysis

ON THE IMPORTANT MODULATION-FREQUENCY BANDS OF SPEECH FOR HUMAN SPEAKER RECOGNITION

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ON THE IMPORTANT MODULATION-FREQUENCY BANDS OF SPEECH FOR HU...