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Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis

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Stroke & Vascular Neurology 2022年第1期7卷 77-85页

作者： Linda LD Zhong Ya Zheng Alexander Y lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu Hong Kong Chinese Medicine Clinical Study Centre School of Chinese MedicineHong Kong Baptist UniversityHong Kong SARChina Department of Medicine and Therapeutics and Hong Kong Institute of Integrative Medicine Prince of Wales HospitalFaculty of MedicineThe Chinese University of Hong KongHong Kong SARChina Department of Health Research Methods Evidence and ImpactMcMaster UniversityHamiltonOntarioCanada Clinical Laboratory Shanghai Traditional Chinese Medicine Integrated Institute of Vascular AbnomaliesShanghaiChina Institute of Medical Research Northwestern Polytechnical UniversityXi'anShanxiChina Evidence Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhouChina School of Chinese medicine Hong Kong Baptist UniversityHong Kong SARChina Brain Center Guangdong Procincial Hospital of Traditional Chinese MedicineGuangdong University of Chinese MedicineGuangzhouChina The Nethersole School of Nuring Faculty of Medicinethe Chinese University of Hong KongHong Kong SARChina Department of Medicine Li Ka Shing Faculty of Medicinethe University of Hong KongHong Kong SARChina Department of Rehabilitation Sciences Hong Kong Polytechnic UniversityHong Kong SARChina Hong Kong Association for Integration of Chinese-Western Medicine Limited Hong Kong SARChina

Background Stroke is a major cause of death or long-term disability *** patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal ***,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke *** The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM *** The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were ***,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were *** included outcomes were dependency,motor function,depression and swallowing *** analysis was performed,and publication bias was assessed using funnel *** of review 58 studies and 6339 patients were included in the *** analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy *** superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also *** Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy ***,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn ***,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined.

关键词： acupuncture routine alone

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Geodesic metrics on fractals and applications to heat kernel estimates

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Science China Mathematics 2023年第5期66卷 907-934页

作者： Qingsong Gu Ka-Sing lau Hua Qiu Huo-Jun Ruan Department of Mathematics Nanjing UniversityNanjing 210093China Department of Mathematics The Chinese University of Hong KongHong KongChina Department of Mathematics University of PittsburghPittsburghPA 15217USA School of Mathematical Sciences Zhejiang UniversityHangzhou 310027China

It is well known that for a Brownian motion, if we change the medium to be inhomogeneous by a measure μ, then the new motion(the time-changed process) will diffuse according to a different metric D(·, ·).In 2009, Kigami initiated a general scheme to construct such metrics through some self-similar weight functions g on the symbolic space. In order to provide concrete models to Kigami’s theoretical construction, in this paper,we give a thorough study of his metric on two classes of fractals of primary importance: the nested fractals and the generalized Sierpinski carpets;we further assume that the weight functions g := ga are generated by“symmetric” weights a. Let M be the domain of a such that Dgadefines a metric, and let S be the boundary of M. One of our main results is that the metrics from ga satisfy the metric chain condition if and only if a ∈ *** determine M and S, we provide a recursive weight transfer construction on the nested fractals, and a basic symmetric argument on the Sierpinski carpet. As an application, we use the metric chain condition to obtain the lower estimate of the sub-Gaussian heat kernel. This together with the upper estimate obtained by Kigami allows us to have a concrete class of metrics for the time change, and the two-sided sub-Gaussian heat kernel estimate on the fundamental fractals.

关键词： Brownian motion heat kernel metric chain condition nested fractal quasisymmetry resistance metric Sierpinski carpet weight function

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Urocortin and cardiovascular protection

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Acta Pharmacologica Sinica 2004年第3期25卷 3-11页

作者： Chi-wai lau,Yau-chi CHAN,Suk-ying TSANG,Franky Leung CHAN The Chinese University of Hong Kong Hong Kong China Department of Anatomy The Chinese University of Hong Kong Hong Kong China Department of Anatomy The Chinese University of Hong Kong Hong Kong China Department of Anatomy The Chinese University of Hong Kong Hong Kong China Department of Anatomy

Urocortin and other hypothalamus corticotropin-releasing factor (CRF) polypeptides play biologically diverse roles in the stress, cardiovascular and inflammatory responses by acting on central and peripheral CRF receptors. Urocortin shows a significantly high sequence homology to CRF, and the concurrent expression of type-2 CRF (CRF2) receptors with urocortin in the heart suggests that urocortin may play a physiological role in the cardiac function. Urocortin is thought to be the endogenous agonist producing the cardiovascular actions previously attributed to CRF. This review highlights the current novel findings on the molecular and cellular mechanisms by which urocortin may exert its cardiovascular protective action.

关键词： urocortin corticotropin-releasing hormone vascular smooth muscle heart vasodilaion second messenger system protein kinases

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Automatic analysis of deep-water remotely operated vehicle footage for estimation of Norway lobster abundance

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Frontiers of Information Technology & Electronic Engineering 2018年第8期19卷 1042-1055页

作者： Ching Soon TAN Phooi Yee lau Paulo L.CORREIA Aida CAMPOS Centre for Computing and Intelligent Systems Universiti Tunku Abdul RahmanKampar 31900Malaysia lnstituto de Telecomunicaqoes Instituto Superior TecnicoAv.Rovisco Pais1Lisbon 1049-001Portugal Instituto Portugues do Mar e da Atmosfera(IPMA) Divisao de Modelacao e Gestao de Recursos da PescaLisbon 1749-077Portugal Centro de Ciencias do Mar(CCMAR)-Campus de Gambelas Faro 8005-139Portugal

Underwater imaging is being used increasingly by marine biologists as a means to assess the abundance of marine resources and their biodiversity. Previously, we developed the first automatic approach for estimating the abundance of Norway lobsters and counting their burrows in video sequences captured using a monochrome camera mounted on trawling gear. In this paper, an alternative framework is proposed and tested using deep-water video sequences acquired via a remotely operated vehicle. The proposed framework consists of four modules:(1) preprocessing,(2) object detection and classification,(3) object-tracking, and(4) quantification. Encouraging results were obtained from available test videos for the automatic video-based abundance estimation in comparison with manual counts by human experts(ground truth). For the available test set, the proposed system achieved 100%precision and recall for lobster counting, and around 83% precision and recall for burrow detection.

关键词： Object detection Object tracking Feature extraction Remotely operated vehicle(ROV)

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Cu2O-templated fabrication of Ni(OH)2·0.75H2O hollow tubes for electrocatalytic oxygen evolution reaction

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Progress in Natural Science:Materials International 2022年第5期32卷 554-560页

作者： Yu Zhang Xueai Teng Zequn Ma Rongming Wang Woon-Ming lau Aixian Shan Beijing Advanced Innovation Center for Materials Genome Engineering & Center for Green Innovation School of Mathematics and Physics University of Science and Technology Beijing Beijing Advanced Innovation Center for Materials Genome Engineering Beijing Key Laboratory for Magneto-Photoelectrical Composite and Interface Science School of Mathematics and Physics University of Science and Technology Beijing Institute of Materials Science and Devices School of Materials Science and Engineering Suzhou University of Science and Technology Shunde Innovation School of University of Science and Technology Beijing

Cu2O is an ideal template material for the preparation of transition metal hydroxide/oxyhydroxides with oxygen evolution reaction(OER) enhanced catalytic performance. Here, inspired by Pearson’s principle, Cu2O wires were prepared and used as a sacrificial template to prepare Ni(OH)2·0.75H2O hollow tubes(Ni(OH)2HTs) with highly improved surface roughness. Benefiting from unique structural advantages, the Ni(OH)2HTs showed excellent catalytic activity, rapid kinetics and a long-term stability as the OER catalyst, where an overpotential of only 207mV was required to drive a current density of 10 mA cm-2, an ideal kinetics with a Tafel slope as 79.8 mV dec-1was calculated, and no obvious attenuation in chronoamperometry was discovered after operation for 24 h. This paper provides a novel template-assisted strategy to prepare high-performance transition metal-based OER catalysts possessing hollow and tubular structures.

关键词： Ni(OH)2 hollow tube Cu2O wire Template One-dimensional hollow structure Oxygen evolution reaction

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Advances in depressants used for pyrite fotation separation from coal/minerals

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International Journal of Coal Science & Technology 2022年第4期9卷 29-48页

作者： Yulong Li Gan Cheng Mengni Zhang Yijun Cao Ee Von lau College of Chemistry and Chemical Engineering Henan Polytechnic UniversityJiaozuo 454000China Henan Key Laboratory of Coal Green Transformation Henan Polytechnic UniversityJiaozuo 454000China Collaborative Innovation Center of Coal Work Safety and Clean High Efciency Utilization Henan Polytechnic UniversityJiaozuo 454000China School of Chemical Engineering Zhengzhou UniversityZhengzhou 450000China School of Engineering Monash University MalaysiaSelangor 47500Malaysia

Pyrite is separated from other minerals mainly by ***,the hydrophilicity of pyrite is afected by many factors,causing it to easily enter the concentrate and consequently reduce the quality of *** efcient pyrite depressants can be selectively adsorbed on the surface of pyrite to improve its hydrophilicity,thereby increasing the fotation separation *** the fundamental inhibition mechanism of depressants on pyrite is a prerequisite to improve the fotation desulfurization *** inhibition ability and mechanism of diferent types of pyrite depressants are reviewed in this *** recent years,molecular simulation has increasingly become a powerful tool to study the interaction between reagents and minerals,shedding new light on the adsorption mechanisms of reagents on mineral surfaces at the atomic and electronic *** properties of sulfde mineral and fotation reagents as well as the microscopic adsorption mechanistic studies of reagents on mineral surfaces based on quantum chemistry and molecular simulation are also reviewed.

关键词： Pyrite Flotation Depressant Coal Mineral

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Evolution of biomass particles during pelletization process

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Particuology 2024年第3期86卷 182-187页

作者： Hamid Rezaei Maryam Tajilrou Jun Sian Lee Kanages Singaraveloo Anthony lau Shahab Sokhansanj Biomass and Bioenergy Research Group Department of Chemical and Biological EngineeringUniversity of British ColumbiaVancouverCanada

Pulverizing is an essential unit operation in co-firing biomass with *** are only compatible with pellet forms of fibrous biomass materials and crush them down to their original forming particle *** is why the data on the size distribution of the particles forming a biomass pellet is crucial to achieving optimum combustion *** current study determines the internal particle size distribution of pellets after wet disintegration,following Iso 17830 standard,and aims to suggest improvements to the mentioned standard based on new measured *** were carried out on white wood pellets(no bark)and brown wood pellets containing bark at four water temperatures:20,40,60,and 95℃,with or without *** particle size distribution of the pre-pelletizer wood particles was also measured and compared with particles in the formed *** water temperature of 20℃ was found to be adequate for the complete disintegration of pellets,and no mechanical stirring was *** 30% of particles in the disintegrated pellets were 0.5-1.0 *** changes the particle size distribution to smaller *** disintegrated bark pellets contained more fines than white pellets.

关键词： Wood pellets Particle sizes distribution Wet disintegration Stirring Water temperature

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A novel method for the green utilization of waste fried oil

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Particuology 2024年第1期84卷 1-11页

作者： Gan Cheng Mengni Zhang Yang Lu Yanhui Zhang Bin Lin Ee Von lau College of Chemistry and Chemical Engineering Henan Polytechnic UniversityJiaozuo454003China Henan Key Laboratory for Green and Efficient Mining&Comprehensive Utilization of Mineral Resources Henan Polytechnic UniversityJiaozuo454003China Collaborative Innovation Center of Coal Work Safety and Clean High Efficiency Utilization Henan Polytechnic UniversityJiaozuo454003China School of Engineering Monash University MalaysiaSubang JayaSelangor47500Malaysia

Waste fried oil was studied to prepare three different types of detergent such as soap,liquid soap and soap powder via saponification *** preparation conditions of soap base were optimized by orthogonal *** specific preparation processes included waste fried oil treatment,orange peel extract preparation,saponification,demoulding and *** showed that the optimal con-ditions for saponification were as follows:ratio of pure waste fried oil to coconut oil=6∶4,alkali liquor(NaOH)mass fraction 30%,saponification temperature 70℃,orange peel extract concentration 15%.The mature soap was then used to make liquid soap and soap powder by surfactant(sodium dodecylbenzene sulfonate,coconut diethanol amide)addition,followed by *** prepared detergent conforms to the production standard of strong decontamination ability,possesses stable performance,is gentle to skin and non-toxic.

关键词： Waste fried oil Detergent Saponification Decolorization

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Statistical Analysis of Tropical Disturbances over the South China Sea During 1997-2006

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Journal of Ocean University of China 2011年第2期10卷 99-105页

作者： WANG Lei lau Kai Hon Department of Atmospheric Sciences School of Environmental Science and Engineering Sun Yat-sen University Guangzhou 510275 P. R. China Institute of Tropical and Marine Meteorology China Meteorological Administration Guangzhou 510058 P. R. China Institute for the Environment Hong Kong University of Science and Technology Hong Kong P. R. China

Tropical disturbances over the South China Sea (SCS) during the period of 1997-2006 are analyzed using the Tropical Storm and Hurricane WX products. A total of 158 tropical disturbances were formed over the SCS from 1997 to 2006, with 54 de-veloping tropical disturbances which developed into tropical depressions and 104 non-developing tropical disturbances which never developed into tropical depressions. The development rate of tropical disturbances into tropical depressions was 34.18% in these ten years. During the period of this study, total annual numbers of tropical disturbances and developing tropical disturbances over the SCS had significant decreasing trends; however, the development rate of tropical disturbances had an insignificant increasing trend.

关键词： tropical disturbance South China Sea tropical cyclone

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Development and controversies of adjuvant therapy for pancreatic cancer

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Hepatobiliary & Pancreatic Diseases International 2008年第2期7卷 121-125页

作者： Wan-Yee lau Eric C.H.Lai Faculty of Medicine the Chinese University of Hong Kong Prince of Wales Hospital Shatin New TerritoriesHong Kong SAR China

BACKGROUND: Pancreatic cancer is an aggressive malignancy with a dismal prognosis. Radical surgery provides the only chance for a cure with a 5-year survival rate of 7%-25%. An effective adjuvant therapy is urgently needed to improve the surgical outcome. This review describes the current status of adjuvant therapy for pancreatic cancer, and highlights its controversies. DATA SOURCES: A Medline database search was performed to identify relevant articles using the keywords 'pancreatic neoplasm', and 'adjuvant therapy'. Additional papers were identified by a manual search of the references from the key articles. RESULTS: Eight prospective randomized controlled trials (RCTs) on the use of adjuvant chemotherapy and chemoradiation for pancreatic cancer could be identified. The results for adjuvant regimens based on systemic 5-fluorouracil with or without external radiotherapy were conflicting. The recent two RCTs on gemcitabine based regimen gave promising results. CONCLUSIONS: Based on the available data, no standard adjuvant therapy for pancreatic cancer can be established yet. The best adjuvant regimen remains to be determined in large-scale RCTs. Future trials should use a gemcitabine based regimen.

关键词： pancreatic neoplasm pancreatectomy adjuvant therapy radiotherapy chemotherapy

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