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COMPOSITE NATURAL ORBITAL METHOD—A TEST ON BIPYRROLH

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原子与分子物理学报 1990年第4期7卷 1580-1584页

作者： yuichi Yamamoto Takeshi Noro Kimio Ohno Department of Chemistry Faculty of ScienceHokkaido UniversitySapporo060JapanDepartment of ChemistryFaculty of ScienceHokkaido UniversitySapporo060JapanDepartment of ChemistryFaculty of ScienceHokkaido UniversitySapporo060Japan

A scheme for construction of virtual orbitals for use in a configuration interaction(CI) method is described and is applied to the 2,2'-bipyrrole moecule.

关键词：量子化学自洽场分子轨道双吡咯

Development of a pendulum machine for measuring contact lens friction

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Biosurface and Biotribology 2021年第3期7卷 154-161页

作者： Kiyoshi Mabuchi Hiroko Iwashita Rina Sakai Masanobu Ujihira yuichi Hori Department of Biomedical Engineering Kitasato University1-15-1KitasatoSagamiharaJapan Graduate School of Medicine Toho University5-21-16OmorinishiOta-kuTokyoJapan

The lubrication ability of a contact lens is one of its most essential properties because high friction on an eyelid causes discomfort during *** measurements allow assessment of lubrication *** far,several apparatuses have been developed to measure contact lens ***,thus far,ocular physiological conditions including sliding speed and area have been imperfectly ***,a pendulum-type friction tester was developed for the assessment of contact lenses under physiological conditions.A high sliding speed of 90 mm/s was achieved thanks to the short oscillation period of the small ***,the sliding surface on a contact lens was realised at the fulcrum of the *** coefficient of friction for the interaction between a contact lens and plastic hemisphere was directly calculated from the decay in potential energy during the free libration of the *** coefficient of a commercially available contact lens in saline solution,0.1%and 0.3%HA solutions were 0.036,0.039 and 0.050,*** results were reliable because they ranged within the low levels reported by previous *** was shown that the present pendulum machine represents a major advancement in the realisation of physiologically realistic contact lens friction measurement.

关键词： linking apparatus oscillation

Invasive ductal carcinoma of the pancreas showing exophytic growth

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Hepatobiliary & Pancreatic Diseases International 2009年第1期8卷 97-102页

作者： yuichi Sanada Kazuhiro Yoshida Masaoki Itoh Riki Okita Morihito Okada Department of Surgical Oncology Research Institution for Radiation Biology and MedicineHiroshima University

BACKGROUND:Invasive pancreatic carcinoma generally appears as poorly defined mass reflecting the infiltrative *** aimed to identify the histological and immunohistochemical features in a rare case of pancreatic carcinoma showing exophytic growth. METHODS:A 67-year-old woman presented with a mass of 5.0 cm in diameter in the pancreatic *** computed tomography revealed a well-demarcated, primarily solid mass with a central low-density area. Magnetic resonance cholangiopancreatography revealed neither encasement nor dilation of the main pancreatic *** incorrect preoperative diagnosis was made of solid pseudopapillary tumor of the *** serum carcinoembryonic antigen(CEA)levels and abnormal FDG positron emmission tomography accumulation suggested that the tumor had malignant potential requiring a pancreatoduodenectomy. RESULTS:The head of the pancreas contained a well- circumscribed encapsulated mass of 5.0 cm in diameter, comprising 50%adenocarcinoma,with mucinous carci- noma in the center and anaplastic carcinoma at the *** anaplastic carcinoma comprised pleo- morphic cells(PCs)and pleomorphic giant cells(PGCs). The PGCs phagocytozed mononuclear PCs and lymphocytes adjacent to the capsule without infiltrating the capsule *** revealed that the anaplastic carcinoma cells including PGCs were positive for the tumor antigen Mucin 1 and CEA but negative for vimentin. CONCLUSION:Our observations suggest anaplastic carcinoma components in the present tumor have a ductal origin and that the exophytic tumor growth is associated with the phagocytotic activity of PGCs.

关键词： pancreatic carcinoma anaplastic carcinoma mucinous carcinoma Mucin 1 carcinoembryonic antigen

Preface to the Special Issue on recent advances in the study of Equatorial Plasma Bubbles and Ionospheric Scintillation

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Earth and Planetary Physics 2021年第5期5卷 365-367页

作者： yuichi Otsuka Luca Spogli S.Tulasi Ram GuoZhu Li Institute for Space-Earth Environmental Research Nagoya UniversityJapan Istituto Nazionale di Geofisicae Vulcanologia Italy Indian Institute of Geomagnetism India Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China

The 2 nd Equatorial Plasma Bubble(EPB)workshop,funded by the Institute of Geology and Geophysics,Chinese Academy of Sciences,and the National Natural Science Foundation of China,took place in Beijing,China during September 13–15,*** EPB workshop belongs to a conference series that began in 2016 in Nagoya,Japan at the Institute for Space-Earth Environmental Research,Nagoya University,resulting in a special issue of Progress in Earth and Planetary Science that focused on *** main goal of the series is to organize in-depth discussion by scientists working on ionospheric irregularities,and solve the scientific challenges in EPB and ionospheric scintillation *** 2 nd EPB workshop gathered almost 60 scientists from seven countries.A total of 20 invited and contributing papers focusing on ionospheric irregularities and scintillations were *** we briefly comment on 10 papers included in this special issue.

关键词： equatorial plasma bubble ionospheric irregularity and scintillation plasma instability 2nd EPB workshop

Introduction of DT40 cells into chick embryos

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Asian Journal of Andrology 2001年第1期3卷 49-53页

作者： Mariko Toba Fumio Ebara Hiroki Furuta yuichi Matsushimal Yasuo Kitagawa Noboru Fujihara Animal Resource Science Section Division of Bioresource and Bioenvironmental SciencesGraduate School Kyushu UniversityFukuoka812-8581 Japan Graduate Program for Regulation of Biological Signals Graduate School of Bioagricultural ScienceNagoya UniversityNagoya464一8601 Japan

Aim:To examine the transfection of exogenous genes into chick embryos,applying the characteristics of avianleukosis vires(ALV)-induced chicken B cell line DT40 to the production of chimeric ***:The DT40cells incorporated with exogenous gene(lacZ constructs encoding Escherichia coliβ-galactosidase:β-gal)were intro-duced into chick embryos by the injection of cells into stage X *** eggs were incubated for 3(trial1)or 6(trial 2)days,and the expression of lacZ DNA was detected by a histochemical staining method ofβ-galactosi-dase and polymerase chain reaction(PCR)***:The survival rates of the manipulated embryos incu-bated for 3 days(stage 18-20:trial 1)and 6 days(stage 28,30:trial 2)were about 42%and 38%,*** expression rates of the lacZ gene in the embryos in the trials 1 and 2 were about 60%and 23%,respectively,forthe survived ***:The rate of embryonic viability and expression rate of introduced genes were notso high,but it suggested the possibility of utilizing the DT40 cells as a vector for carrying exogenous genes into chickembryos.

关键词： DT40 cells chick embryo lacZ polymerase chain reaction

Management of gastric and duodenal neuroendocrine tumors

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World Journal of Gastroenterology 2016年第30期22卷 6817-6828页

作者： yuichi Sato Satoru Hashimoto Ken-ichi Mizuno Manabu Takeuchi Shuji Terai Department of Gastroenterology Niigata University Graduate School of Medical and Dental Sciences Division of Endoscopy Niigata University Medical and Dental Hospital

Gastrointestinal neuroendocrine tumors (GI-NETs) are rare neoplasms, like all NETs. However, the incidence of GI-NETS has been increasing in recent years. Gastric NETs (G-NETs) and duodenal NETs (D-NETs) are the common types of upper GI-NETs based on tumor location. G-NETs are classified into three distinct subgroups: type I, II, and III. Type I G-NETs, which are the most common subtype (70%-80% of all G-NETs), are associated with chronic atrophic gastritis, including autoimmune gastritis and Helicobacter pylori associated atrophic gastritis. Type II G-NETs (5%-6%) are associated with multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome (MEN1-ZES). Both type I and II G-NETs are related to hypergastrinemia, are small in size, occur in multiple numbers, and are generally benign. In contrast, type III G-NETs (10%-15%) are not associated with hypergastrinemia, are large-sized single tumors, and are usually malignant. Therefore, surgical resection and chemotherapy are generally necessary for type III G-NETs, while endoscopic resection and follow-up, which are acceptable for the treatment of most type I and II G-NETs, are only acceptable for small and well differentiated type III G-NETs. D-NETs include gastrinomas (50%-60%), somatostatin-producing tumors (15%), nonfunctional serotonin-containing tumors (20%), poorly differentiated neuroendocrine carcinomas (< 3%), and gangliocytic paragangliomas (< 2%). Most D-NETs are located in the first or second part of the duodenum, with 20% occurring in the periampullary region. Therapy for D-NETs is based on tumor size, location, histological grade, stage, and tumor type. While endoscopic resection may be considered for small nonfunctional D-NETs (G1) located in the higher papilla region, surgical resection is necessary for most other D-NETs. However, there is no consensus regarding the ideal treatment of D-NETs.

关键词： Gastric neuroendocrine tumors Duodenal neuroendocrine tumors Classification Endoscopic treatment Endoscopic submucosal dissection

A tree detection method based on trunk point cloud section in dense plantation forest using drone Li DAR data

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Forest Ecosystems 2023年第1期10卷 37-45页

作者： Yupan Zhang Yiliu Tan yuichi Onda Asahi Hashimoto Takashi Gomi Chenwei Chiu Shodai Inokoshi Center for Research in Isotopes and Environmental Dynamics University of Tsukuba1-1-1TennodaiTsukubaIbaraki305-8572Japan Graduate School of Systems and Information Engineering University of Tsukuba1-1-1TennodaiTsukubaIbaraki305-8572Japan Department of International Environmental and Agricultural Science Tokyo University of Agriculture and Technology3-5-8SaiwaieFuchuTokyo183-8509Japan

Single-tree detection is one of the main research topics in quantifying the structural properties of forests. Drone Li DAR systems and terrestrial laser scanning systems produce high-density point clouds that offer great promise for forest inventories in limited areas. However, most studies have focused on the upper canopy layer and neglected the lower forest structure. This paper describes an innovative tree detection method using drone Li DAR data from a new perspective of the under-canopy structure. This method relies on trunk point clouds, with undercanopy sections split into heights ranging from 1 to 7 m, which were processed and compared, to determine a suitable height threshold to detect trees. The method was tested in a dense cedar plantation forest in the Aichi Prefecture, Japan, which has a stem density of 1140 stems·ha^(-1) and an average tree age of 42 years. Dense point cloud data were generated from the drone Li DAR system and terrestrial laser scanning with an average point density of 5000 and 6500 points·m^(-2), respectively. Tree detection was achieved by drawing point-cloud section projections of tree trunks at different heights and calculating the center coordinates. The results show that this trunk-section-based method significantly reduces the difficulty of tree detection in dense plantation forests with high accuracy(F1-Score=0.9395). This method can be extended to different forest scenarios or conditions by changing section parameters.

关键词： Tree detection Trunk sections Forest Drone LiDAR

Ensemble learning framework for landslide susceptibility mapping:Different basic classifier and ensemble strategy

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Geoscience Frontiers 2023年第6期14卷 170-190页

作者： Taorui Zeng Liyang Wu Dario Peduto Thomas Glade yuichi S.Hayakawa Kunlong Yin Institute of Geological Survey China University of GeosciencesWuhan 430074China ENGAGE—Geomorphic Systems and Risk Research Department of Geography and Regional ResearchUniversity of Vienna1010 ViennaAustria Faculty of Engineering China University of GeosciencesWuhanChina Department of Civil Engineering University of Salerno84084 SalernoFiscianoItaly Faculty of Environmental Earth Science Hokkaido UniversityHokkaido 060-0810Japan

The application of ensemble learning models has been continuously improved in recent landslide susceptibility research,but most studies have no unified ensemble ***,few papers have discussed the applicability of the ensemble learning model in landslide susceptibility mapping at the township *** study aims at defining a robust ensemble framework that can become the benchmark method for future research dealing with the comparison of different ensemble *** this purpose,the present work focuses on three different basic classifiers:decision tree(DT),support vector machine(SVM),and multi-layer perceptron neural network model(MLPNN)and two homogeneous ensemble models such as random forest(RF)and extreme gradient boosting(XGBoost).The hierarchical construction of deep ensemble relied on two leading ensemble technologies(i.e.,homogeneous/heterogeneous model ensemble and bagging,boosting,stacking ensemble strategy)to provide a more accurate and effective spatial probability of landslide *** selected study area is Dazhou town,located in the Jurassic red-strata area in the Three Gorges Reservoir Area of China,which is a strategic economic area currently characterized by widespread landslide *** on a long-term field investigation,the inventory counting thirty-three slow-moving landslide polygons was *** results show that the ensemble models do not necessarily perform better;for instance,the Bagging based DT-SVM-MLPNNXGBoost model performed worse than the single XGBoost *** the eleven tested models,the Stacking based RF-XGBoost model,which is a homogeneous model based on bagging,boosting,and stacking ensemble,showed the highest capability of predicting the landslide-affected ***,the factor behaviors of DT,SVM,MLPNN,RF and XGBoost models reflected the characteristics of slow-moving landslides in the Three Gorges reservoir area,wherein unfavorable lithological conditions and intense human engineering activitie

关键词： Three Gorges Reservoir Area Landslide susceptibility mapping Ensemble learning framework Uncertainty research

Surgical spacer placement and proton radiotherapy for unresectable hepatocellular carcinoma

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World Journal of Gastroenterology 2010年第14期16卷 1800-1803页

作者： Shohei Komatsu yuichi Hori Takumi Fukumoto Masao Murakami Yoshio Hishikawa Yonson Ku Department of Surgery Division of Hepato-Biliary-Pancreatic Surgery Kobe University Graduate School of Medicine Kobe 650-0017 Japan Department of Radiology Hyogo Ion Beam Medical Center Tatsuno 679-5165 Japan

Few potentially curative treatment options exist apart from hepatic resection for patients with huge hepatocellular carcinoma (HCC). Proton radiotherapy is a promising new modality which has an inherent antitumor effect against HCC. However, the application of proton radiotherapy for tumors adjacent to the gastrointestinal tract is restricted because the tolerance dose of the intestine is extremely low. A novel two-step treatment was developed with surgical spacer placement and subsequent proton radiotherapy to administer proton radiotherapy with curative intent. This report presents a case of a patient with a huge unresectable HCC treated by this method who achieved disease-free survival of more than 2 years. This new strategy may potentially be an innovative and standard therapy for unresectable HCC in the near future.

关键词： Hepatocellular carcinoma Proton radio-therapy Particle radiotherapy Operative surgical procedures