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Experimental constraints on the formation of oxychlorine species by UV irradiation and mechanical pulverization on the lunar surface

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Acta Geochimica 2024年第4期43卷 625-637页

作者： Jiamei Li Yu-Yan Sara Zhao He Cui Shuai-Yi Qu Yanhua Peng yuhong Yang Xiongyao Li Research Center for Planetary Science College of Earth and Planetary SciencesChengdu University of TechnologyChengdu 610059China Center for Excellence in Comparative Planetology Chinese Academy of SciencesHefei 230026China College of Life Sciences Wuchang University of TechnologyWuhan 430204China Technical Center of Qingdao Customs Qingdao 266114China Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China Nanning College of Technology Guilin 541006China Center for Lunar and Planetary Sciences Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China

Perchlorate and chlorate are present in various extraterrestrial celestial bodies throughout the solar system,such as Mars,the moon,and *** date,the origin mechanisms of perchlorate and chlorate on the Martian surface have been well-established;however,relatively little attention has been cast to airless ***,we experimentally investigated the potential oxidation mechanisms of chloride to chlorate and perchlorate,such as ultraviolet irradiation under H_(2)O-and O_(2)-free conditions and mechanical pulverization *** minerals,olivine,pyroxene,ilmenite,magnetite,TiO_(2)and anhydrous ferric sulfate,and lunar regolith simulants(low Ti,CLRS-1;high-Ti,CLRS-2)and their metallic iron(Fe^( 0))bearing counterparts were *** found that pulverization of dry matrix material-halite mixtures,even in the presence of O_(2),does not necessarily lead to perchlorate and chlorate formation without involving *** photocatalytic and H_(2)O and O_(2)-free conditions,olivine and pyroxene can produce oxychlorine(ClO_(x)^(−))species,although the yields were orders of magnitude lower than those under Martian-relevant ***-Fe^(0)particles in the lunar regolith and the common photocatalyst TiO_(2)can facilitate the ClO_(x)^(−)formation,but their yields were lower than those with *** oxides ilmenite and magnetite did not efficiently contribute to ClO_(x)^(−)*** results highlight the critical role of H_(2)O in the oxidation chloride to chlorate and perchlorate,and provide essential insights into the environmental influence on the formation of oxychlorine species on different celestial bodies.

关键词： Perchlorate Chlorate Lunar regolith Metallic Fe Airless bodies

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Genome editing of PAR2 through targeted delivery of CRISPR-Cas9 system for alleviating acute lung inflammation via ERK/NLRP3/IL-1β and NO/iNOS signalling

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1441-1456页

作者： Xin Zhuo Yue Wu Xiujuan Fu Jianbin Li Yuxin Xiang Xiaoyu Liang Canquan Mao yuhong Jiang Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs School of Life Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China

Excessive and uncontrollable inflammatory responses in alveoli can dramatically exacerbate pulmonary disease progressions through vigorous cytokine releases,immune cell infiltration and protease-driven tissue *** is an urgent need to explore potential drug strategies for mitigating lung ***-activated receptor 2(PAR2)as a vital molecular target principally participates in various inflammatory diseases via intracellular signal ***,it has been rarely reported about the role of PAR2 in lung *** study applied CRISPR-Cas9 system encoding Cas9 and sg RNA(p Cas9-PAR2)for PAR2 knockout and fabricated an anionic human serum albuminbased nanoparticles to deliver p Cas9-PAR2 with superior inflammation-targeting efficiency and stability(TAP/p Cas9-PAR2).TAP/p Cas9-PAR2 robustly facilitated p Cas9-PAR2 to enter and transfect inflammatory cells,eliciting precise gene editing of PAR2 in vitro and in ***,PAR2 deficiency by TAP/p Cas9-PAR2 effectively and safely promoted macrophage polarization,suppressed proinflammatory cytokine releases and alleviated acute lung inflammation,uncovering a novel value of *** also revealed that PAR2-mediated pulmonary inflammation prevented by TAP/p Cas9-PAR2was mainly dependent on ERK-mediated NLRP3/IL-1β and NO/i NOS ***,this work indicated PAR2 as a novel target for lung inflammation and provided a potential nanodrug strategy for PAR2 deficiency in treating inflammatory diseases.

关键词： Protease-activated receptor 2(PAR2) CRISPR-Cas9 Gene editing Inflammation Acute lung inflammation NLRP3 Nanoparticles Drug delivery

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基于高光谱影像多维特征的植被精细分类

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大气与环境光学学报 2020年第2期15卷 117-124页

作者：苗宇宏杨敏吴国俊中国科学院西安光学精密机械研究所陕西省海洋光学重点实验室陕西西安710119 青岛海洋科学与技术试点国家实验室海洋观测与探测联合实验室山东青岛266235 国家海洋局北海海洋技术保障中心山东青岛266033

目前,高光谱植被精细分类存在三个问题:单纯利用光谱信息得到的分类精度较低;光谱数据存在噪声影响了最终的分类结果;缺少针对具体应用场景而设计的分类方法。为此,提出了一种基于高光谱影像多维特征的植被精细分类方法,通过光谱数据降... 详细信息

目前,高光谱植被精细分类存在三个问题:单纯利用光谱信息得到的分类精度较低;光谱数据存在噪声影响了最终的分类结果;缺少针对具体应用场景而设计的分类方法。为此,提出了一种基于高光谱影像多维特征的植被精细分类方法,通过光谱数据降维、纹理特征提取以及植被指数选择三个方面对高光谱影像数据进行分析与利用,依靠前期现场调查得到的地面植被分布情况,选择训练样本并进行支持向量机(Support vector machine,SVM)监督分类,完成地面植被的精细分类,对分类结果进行验证,总体精度可达99.6%。结果表明,基于高光谱影像多维特征的植被分类方法能够有效地减小数据噪声、提高信息利用率,为植被生态监测提供更为准确的数据支撑。

关键词：高光谱光谱降维纹理特征植被指数支持向量机

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Research on the Implementation Path of Ideological and Political Education in the“Horticultural Plant Production Technology”Course under the Rural Revitalization Strategy

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Journal of Contemporary Educational Research 2024年第8期8卷 32-37页

作者： yuhong Yuan Fujian Forestry Vocational Technical College Nanping 353000Fujian ProvinceChina

The horticultural industry plays an important role in the rural revitalization *** the core course of horticultural technology,“Horticultural Plant Production Technology”shoulders an important mission in serving the rural revitalization strategy and cultivating a group of rural revitalization talents who truly love agriculture,know agricultural techniques,and understand *** the dimension of ideological and political education in the curriculum,based on the strategy of rural revitalization,the implementation path of ideological and political education in the curriculum is expanded and improved from the construction of education models,curriculum team building,excavation of ideological and political elements,and construction of evaluation systems,in order to improve the level of ideological and political education in horticultural plant production technology courses and provide certain reference and guidance for the ideological and political construction of similar agricultural vocational education courses.

关键词： Rural revitalization Agricultural vocational education Ideological and political education Implementation path

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捷联惯组批次性能评估的稳健方法与应用

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航天控制 2008年第1期26卷 18-21页

作者：方喜龙周江华苗育红第二炮兵工程学院西安710025 中国科学院光电研究所北京100028

针对目前惯组批次性能评估方法中存在易受异常样本影响和结果无法检验的问题,提出了两种基于中位数理论的高效率稳健评估方法,称为rp方法与稳健标准差方法。两种方法合理利用了评估过程中的稳健信息,有效地克服了异常样本的影响,并且在... 详细信息

针对目前惯组批次性能评估方法中存在易受异常样本影响和结果无法检验的问题,提出了两种基于中位数理论的高效率稳健评估方法,称为rp方法与稳健标准差方法。两种方法合理利用了评估过程中的稳健信息,有效地克服了异常样本的影响,并且在此基础上构建了一套完备的批次惯组评估模型,确保统计结果准确可靠。最后,文中给出了具体的工程应用实例和结果分析。

关键词：中位数异常样本圆概率偏差

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Integrated unified phase-field modeling(UPFM)

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Materials Genome Engineering Advances 2024年第2期2卷 25-38页

作者： yuhong Zhao Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijingChina School of Materials Science and Engineering North University of ChinaTaiyuanChina Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyangChina

For a long time,the phase-field method has been considered a mesoscale phenomenological method that lacks physical accuracy and is unable to be closely linked to the mechanical or functional properties of *** misunderstandings existing in these viewpoints need to be ***,it is necessary to propose or adopt the perspective of“unified phase-field modeling(UPFM)”to address these issues,which means that phase-field modeling has multiple unified ***,the phase-field method is the perfect unity of thermodynamics and kinetics,the unity of multi-scale models from microto meso and then to macro,the unity of internal or/and external driving energy with order parameters as field variables,the unity of multiple physical fields,and thus the unity of material composition design,process optimization,microstructure control,and performance *** is precisely because the phase-field approach has these unified characteristics that,after more than 40 years of development,it has been increasingly widely applied in materials science and engineering.

关键词： entire process gradient potential driving force multi physical fields multiscale/multiple order parameters thermodynamics and kinetics unified phase-field modeling

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Lactobacillus plantarum J26 alleviates alcohol-induced oxidative liver injury by regulating the Nrf2 signaling pathway

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Food Science and Human Wellness 2024年第4期13卷 2068-2078页

作者： Hongxuan Li Shasha Cheng yuhong Wang Yilin Sun Jiaxin Zhang Mingshuang Sun Chaoxin Man Yu Zhang Yujun Jiang Key Laboratory of Dairy Science Ministry of EducationCollege of Food Science and EngineeringNortheast Agricultural UniversityHarbin 150030China

Oxidative stress is one of the main ways to cause alcohol-induced liver injury,and alcoholic liver disease(ALD)has been a common health problem *** acid bacteria(LAB)is also considered as a potential treatment to alleviate alcohol-induced liver *** plantarum J26 is a LAB isolated from Chinese traditional fermented dairy products with excellent probiotic *** study aimed to establish a mice model of alcoholic liver injury through acute-on-chronic alcohol feeding and to study the alleviating effect of pre-intake of *** J26 on alcohol-induced oxidative liver injury and focus on its potential mechanism of alleviating *** results showed that pre-intake of *** J26 could improve liver pathological changes,reduce lipid accumulation,increase mitochondrial ATP and mitochondrial(mtDNA)levels,and alleviate liver *** addition,pre-intake *** J26 can improve the level of short-chain fatty acids(SCFAs)in the intestines in mice,short chain fatty acids can be used as a signaling molecule activation of nuclear factor E2-related factor 2(Nrf2)signaling pathway to alleviate liver oxidative stress,and maintain mitochondrial homeostasis by regulating the expression of genes related to mitochondrial dynamics and autophagy,thereby reducing cell apoptosis to alleviate alcohol-induced oxidative liver injury.

关键词： Alcoholic liver disease Probiotics Nuclear factor E2-related factor 2(Nrf2) Oxidative stress Short-chain fatty acids

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Non-B-form DNA is associated with centromere stability in newly-formed polyploid wheat

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Science China(Life Sciences) 2024年第7期67卷 1479-1488页

作者： Congyang Yi Qian Liu yuhong Huang Chang Liu Xianrui Guo Chaolan Fan Kaibiao Zhang Yang Liu Fangpu Han Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Non-B-form DNA differs from the classic B-DNA double helix structure and plays a crucial regulatory role in replication and ***,the role of non-B-form DNA in centromeres,especially in polyploid wheat,remains ***,we systematically analyzed seven non-B-form DNA motif profiles(A-phased DNA repeat,direct repeat,G-quadruplex,inverted repeat,mirror repeat,short tandem repeat,and Z-DNA)in hexaploid *** found that three of these non-B-form DNA motifs were enriched at centromeric regions,especially at the CENH3-binding sites,suggesting that non-B-form DNA may create a favorable loading environment for the CENH3 *** investigate the dynamics of centromeric non-B form DNA during the alloploidization process,we analyzed DNA secondary structure using CENH3 ChIP-seq data from newly formed allotetraploid wheat and its two diploid *** found that newly formed allotetraploid wheat formed more non-B-form DNA in centromeric regions compared with their parents,suggesting that non-B-form DNA is related to the localization of the centromeric regions in newly formed ***,non-B-form DNA enriched in the centromeric regions was found to preferentially form on young LTR retrotransposons,explaining CENH3's tendency to bind to younger ***,our study describes the landscape of non-B-form DNA in the wheat genome,and sheds light on its potential role in the evolution of polyploid centromeres.

关键词： non-B-form DNA polyploid wheat centromere retrotransposon

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Structurally Flexible 2D Spacer for Suppressing the Electron-Phonon Coupling Induced Non-Radiative Decay in Perovskite Solar Cells

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Nano-Micro Letters 2024年第9期16卷 325-340页

作者： Ruikun Cao Kexuan Sun Chang Liu yuhong Mao Wei Guo Ping Ouyang Yuanyuan Meng Ruijia Tian Lisha Xie Xujie Lü Ziyi Ge Zhejiang Provincial Engineering Research Center of Energy Optoelectronic Materials and Devices Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201People’s Republic of China School of Materials Science and Chemical Engineering Ningbo UniversityNingbo 315211People’s Republic of China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049People’s Republic of China Center for High Pressure Science and Technology Advanced Research(HPSTAR) Shanghai 201203People’s Republic of China

This study presents experimental evidence of the dependence of non-radiative recombination processes on the electron-phonon coupling of perovskite in perovskite solar cells(PSCs).Via A-site cation engineering,a weaker electron-phonon coupling in perovskite has been achieved by introducing the structurally soft cyclohexane methylamine(CMA^(+))cation,which could serve as a damper to alleviate the mechanical stress caused by lattice oscillations,compared to the rigid phenethyl methylamine(PEA^(+))*** demonstrates a significantly lower non-radiative recombination rate,even though the two types of bulky cations have similar chemical passivation effects on perovskite,which might be explained by the suppressed carrier capture process and improved lattice geometry *** resulting PSCs achieve an exceptional power conversion efficiency(PCE)of 25.5%with a record-high opencircuit voltage(V_(OC))of 1.20 V for narrow bandgap perovskite(FAPbI_(3)).The established correlations between electron-phonon coupling and non-radiative decay provide design and screening criteria for more effective passivators for highly efficient PSCs approaching the Shockley-Queisser limit.

关键词： Electron-phonon coupling A-site cation engineering Non-radiative recombination

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Advancements and New Frontiers in Offshore Seismic Exploration Technology

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Journal of Earth Science 2024年第5期35卷 1749-1757页

作者： yuhong Xie Yunfei Ye Xiaogang Huang Wenbo Sun Yanwen Wei China National Offshore Oil Corporation Beijing 100010China CNOOC Nanhai Oil and Gas Energy Academician Workstation Haikou 570312China CNOOC Research Institute Ltd. Beijing 100028China National Engineering Research Center of Offshore Oil and Gas Exploration Beijing 100028China

0 INTRODUCTION China's external dependence on oil and gas remains high,making the independent exploration and development of oil and gas resources crucial for ensuring national energy security and the sustainable development of the economy and *** 2023,China continued to step up its efforts in offshore oil and gas exploration and development,with offshore crude oil production surpassing 62 million tons,accounting for about 70%of the national increase in crude oil *** offshore oil and gas exploration and development is of great significance for guaranteeing national energy security.

关键词： offshore guarantee continued

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