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Outpatient varicocelectomy performed under local anesthesia

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Asian Journal of Andrology 2005年第4期7卷 439-444,页

作者： Geng-Long Hsu Pei-Ying Ling Cheng-hsing Hsieh Chii-Jye Wang Cheng-Wen Chen Hsien-Sheng Wen Hsiu-Mei Huang E.Ferdinand Einhorn Guo-Fang Tseng Microsurgical Potency Reconstruction and Research Center Taiwan Adventist HospitalTaipei Medical UniversityTaipei 110TaiwanChina Department of Anatomy and Cell Biology College of MedicineNational Taiwan UniversityTaipei 100TaiwanChina

Aim： To report a series of varicocelectomy performed under pure local anesthesia. Methods： From July 1988 to June 2003, a total of 575 patients, aged between 15 and 73 years, underwent high ligation of the internal spermatic vein for treatment of a varicocele testis under a regional block in which a precise injection of 0.8 % lidocaine solution was delivered to involved tissues after exact anatomical references were made. A 100-mm visual analog scale （VAS） was used to assess whether the pain level was acceptable. Results： The surgeries were bilateral in 52 cases, and unilateral in 523 cases. All were successfully performed on an outpatient basis except in the case of two patients, who were hospitalized because their surgeries required general anesthesia. Overall, 98.6 % （567/575） of men could go back to work by the end of the first post-operative week and only 8 （1.4 %） men reported feeling physical discomfort on the eighth day. The VAS scores varied from 11 mm to 41 mm with an average of （18.5 ± 11.3） mm that was regarded as tolerable. Conclusion： This study has shown varicocelectomy under local anesthesia to be possible, simple, effective, reliable and reproducible, and a safe method with minimal complications. It offers the advantages of more privacy, lower morbidity, with no notable adverse effects resulting from anesthesia, and a more rapid return to regular physical activity with minor complications.

关键词： anterior superior iliac spine spermatic cord aponeurosis umbilicus pubic symphysis varicocelectomy anesthesia

Reading Chinese with word boundary frames in parafovea preview

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Reading Chinese with word boundary frames in parafovea previ...

Facile Selective Diels-Alder Reactions of Chiral 5, 5-Dimethyl-4,6-Mathano-2-Methoxycarbonyl-2-Cyclohexenone. Application to the Total Synthesis of Qinghaosu

第四届中国国际眼动大会

作者： Chia-hsing Chen Jie-Li Tsai Department of Psychology National Chengchi University

＜正＞The present study investigated the influence of providing word boundary frames for parafoveal preview while reading *** read 6 passages（about 1269 characters/670 words for each passage） for *** difficulty of the reading material was *** the eye-movement contingent display change technique,participants saw the framed or no-frame

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有机化学 1993年第3期 314-321页

作者： LIU hsing-Jang CHEW Sew-Yeu YEH Wen-Lung Department of Chemistry, The University of Alberta, Edmonton, Alberta, Canada T6G 2G2

Starting from (--)-β-pinene,an efficient synthesis of qinghaosu (8) in natural form hasbeen accomplished. The synthesis involves keto ester 7 as a key intermediate which is conveniently pre-pared using the Diels-Alde... 详细信息

关键词： (-)-β-Pinene Diels-Alder reaction synthesis of qinghaosu

Management Perspective on the Evaluation of the Green Accounting in the Corporate Social Responsibility

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Management Perspective on the Evaluation of the Green Accoun...

2019冠状病毒病爆发期间城市居民午睡与抑郁情绪的关系研究

2010 International Conference on Management Science and Engineering (MSE 2010)

作者： Ming-Yuan Hsieh Huang Chung-hsing Huang Department of International Business University of Education College of Management National Taiwan University

Enterprises have always sacrificed the benefits of the human and environmental causes in order to pursue the maximization of companies’ *** more awareness of the concept of environmental protection and Corporate Social Responsibility（CSR）,enterprises have to commence to take the potential duty for the human and the environment beyond the going-concern assumption and the achievement of profits maximization for ***,with reference to vigorous environmental issues（unstable variation of climate,huge fluctuation of the Earth’s crust,abnormal raises of the sea and so on）,the traditional accounting principles and assumptions do conform to the contemporarily social ***,based on the full disclosure principle,enterprises are further supposed to disclose the full financial cost of complying with environment regulations（regarding the dystrophication resulted from operation,amended honorable of contamination,environmental protection policies and so on） which are going to lead to enterprises are still able to achieve "economy-efficiency" for the environments under the go-concern ***,the innovative accounting theory（the Green Accounting Theory） is created to establish new accounting principles and regulations for confronting these *** paper utilizes three essential relations in consolidation that are evaluated by nineteen assessable sub-criteria of four evaluated criteria through the comparison of Multiple Criteria Decision Making（MCDM）-Analytical Network Process（ANP）.Specifically,the specific feature of the three-approach models is to calculate the priority vector weights of each assessable characteristic,criteria and sub-criteria by pairwise comparative ***,in the content,the analytical hierarchical relations are definitely expressed in four levels among each criterion which enable enterprises to choose the potential role of green accounting in CSR in a thriving hypercompetitive commerce environment.

关键词： Corporate Social Responsibility(CSR) Green Accounting(GA) Analytical Network Process(ANP).

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浙江大学学报（医学版） 2021年第6期50卷 741-747页

作者：林文慧白冠男何威杨菲李伟闵燕 LU Ying hsing Ann 朱善宽浙江大学公共卫生学院浙江杭州310058 浙江大学医学院附属儿童医院国家儿童健康与疾病临床医学研究中心国家儿童区域医疗中心浙江杭州310052 美国斯坦福大学医学院流行病学与人口健康学系美国斯坦福943054 美国斯坦福大学医学院生物医学数据科学系美国斯坦福94305

目的:探索2019冠状病毒病(COVID-19)爆发期间城市居民午睡与抑郁情绪的关系,为突发公共卫生事件期间城市居民抑郁情绪的预防提供科学依据。方法:基于WELL中国队列人群,于2020年4月8日至2020年5月29日通过电话访谈获取COVID-19爆发期间... 详细信息

目的:探索2019冠状病毒病(COVID-19)爆发期间城市居民午睡与抑郁情绪的关系,为突发公共卫生事件期间城市居民抑郁情绪的预防提供科学依据。方法:基于WELL中国队列人群,于2020年4月8日至2020年5月29日通过电话访谈获取COVID-19爆发期间被调查者的健康与生活方式信息,最终纳入3075名18~80岁杭州市拱墅区城市居民的调查资料。采用世界卫生组织五项身心健康指标测量抑郁情绪,多元logistic回归模型分析调查对象午睡状况与抑郁情绪的关系。结果:COVID-19爆发期间约有20.6%的城市居民出现抑郁情绪;在一般人群中,有午睡行为尤其是午睡时长不超过30 min与抑郁情绪发生风险(OR=0.61,95%CI:0.47~0.79,P<0.01)、新发抑郁情绪风险(OR=0.66,95%CI:0.50~0.88,P<0.01)较低相关;在有抑郁情绪的城市居民中,仅午睡时长不超过30 min有利于抑郁情绪改善(OR=0.42,95%CI:0.21~0.82,P<0.05)。结论:2019冠状病毒病爆发期间,约有1/5的城市居民存在抑郁情绪,短时间的午睡可能是抑郁情绪的保护因素。

关键词： 2019冠状病毒病抑郁情绪午睡城市居民队列研究

Electrochemistry based Real-Time Polymerase Chain Reaction (PCR) for Point of Care Applications

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Electrochemistry based Real-Time Polymerase Chain Reaction (...

Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance

The Eleventh International and the First Sino-Japan Bilateral Symposium on Electroanalytical Chemistry

作者： I-Ming hsing Thomas Ming Hung leE Department of Chemical Engineering and Bioengineering Graduate Program Hong Kong University of Science and Technology Kowloon Hong Kong SAR China Department of Health Technology and Informatics The Hong Kong Polytechnic University

Nucleic acid based analysis has an important role to play in many critical applications such as medical diagnostics,environmental monitoring and food safety *** the available analytical tools,real time polymerase chain reaction(PCR)has been widely adopted as a viable technique for rapid detection and quantification of trace nucleic acid analytes[1].One challenge to

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Acta Pharmaceutica Sinica B 2022年第4期12卷 1871-1884页

作者： Hong Wang Qianqian Wang Guodi Cai Zhijian Duan Zoann Nugent Jie Huang Jianwei Zheng Alexander D.Borowsky Jian Jian Li Peiqing Liu hsing-Jien Kung leigh Murphy Hong-Wu Chen Junjian Wang School of Pharmaceutical Sciences Sun Yat-sen UniversityGuangzhou 510006China Department of Biochemistry and Molecular Medicine University of CaliforniaDavisSacramentoCA 95817USA Research Institute in Oncology and Hematology University of Manitoba and CancerCare ManitobaWinnipeg R3E 0V9Canada Guangdong Lung Cancer Institute Guangdong Provincial Key Laboratory of Translational Medicine in Lung CancerGuangdong Provincial People’s Hospital and Guangdong Academy of Medical SciencesGuangzhou 510080China Department of Pathology and Laboratory Medicine University of CaliforniaDavisSacramentoCA 95817USA Department of Radiation Oncology University of CaliforniaDavisSacramentoCA 95817USA National-Local Joint Engineering Laboratory of Druggability and New Drugs Evaluation Guangdong Provincial Key Laboratory of New Drug Design and EvaluationSun Yat-sen UniversityGuangzhou 510006China UC Davis Comprehensive Cancer Center School of MedicineUniversity of CaliforniaDavisSacramentoCA 95817USA

Metabolic and epigenetic reprogramming play important roles in cancer therapeutic ***,their interplays are poorly *** report here that elevated TIGAR(TP53-induced glycolysis and apoptosis regulator),an antioxidant and glucose metabolic regulator and a target of oncogenic histone methyltransferase NSD2(nuclear receptor binding SET domain protein 2),is mainly localized in the nucleus of therapeutic resistant tumor cells where it stimulates NSD2 expression and elevates global H3K36me2 ***,TIGAR directly interacts with the antioxidant master regulator NRF2 and facilitates chromatin recruitment of NRF2,H3K4me3 methylase MLL1 and elongating Pol-II to stimulate the expression of both new(NSD2)and established(NQO1/2,PRDX1 and GSTM4)targets of NRF2,independent of its enzymatic *** TIGAR confers cancer cell resistance to chemotherapy and hormonal therapy in vitro and in tumors through effective maintenance of redox *** addition,nuclear accumulation of TIGAR is positively associated with NSD2 expression in clinical tumors and strongly correlated with poor *** findings define a nuclear TIGAR-mediated epigenetic autoregulatory loop in redox rebalance for tumor therapeutic resistance.

关键词： TIGAR NSD2 NRF2 Metabolism Oxidative stress Epigenetic reprogramming Therapeutic resistance Redox homeostasis

Case Report: Gouty Tophus of the Larynx

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International Journal of Otolaryngology and Head & Neck Surgery 2021年第1期10卷 43-48页

作者： Chung-Yu Hao Yih-Jeng Tsai hsing-Mei Wu Chia-Jung lee Department of Otolaryngology Head and Neck Surgery Shin Kong Wu Ho-Su Memorial Hospital Taiwan College of Medicine Fu Jen Catholic University Taiwan

Gout is a metabolic disorder that is characterized by a deposition of monosodium urate crystals in the joint or soft tissue. Gout manifestations in head and neck region are rare, and larynx is an infrequently affected location. We recently managed a case of a gouty tophus over the larynx. A 65-year-old male with a long history of gout without medical control. He has suffered from increasing hoarseness for six months. Laryngoscopy revealed a mass lesion over the right vocal process region without vocal paralysis. Laryngo-micro-surgery biopsy was taken, and pathology confirmed laryngeal gouty tophus without evidence of malignancy.

关键词： Gout Tophus Larynx Purine Monosodium Urate Crystals

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胡适、许地山与香港大学经学教育的变革

湖南大学学报（社会科学版） 2009年第5期23卷 26-30页

作者：车行健台湾政治大学中文系台北11605

胡适于1935年元月参访香港大学时对香港大学的中文教学有颇为尖刻的批评,认为完全掌握在几个"旧式科第文人"的手里。适逢港大当局有意聘请胡适主持中文教学的改革,胡适便向港大校方推荐了许地山以自代。许地山对港大中文教学体制与人员... 详细信息

胡适于1935年元月参访香港大学时对香港大学的中文教学有颇为尖刻的批评,认为完全掌握在几个"旧式科第文人"的手里。适逢港大当局有意聘请胡适主持中文教学的改革,胡适便向港大校方推荐了许地山以自代。许地山对港大中文教学体制与人员进行了重要改革,在这个过程中原有的经学课程被彻底取消。之所以会有这样的情况,固然与经学在现代大学课程体制内处于妾身不明的状况有关,但更主要的因素却可能是跟授课者的讲授效果有关。

关键词：胡适许地山香港大学中文教学经学教育