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Toward Improved Accuracy in Quasi-Static Elastography Using Deep Learning

Computer Modeling in Engineering & Sciences 2024年第4期139卷 911-935页

作者： yue mei Jianwei Deng Dongmei Zhao Changjiang Xiao Tianhang Wang Li Dong Xuefeng Zhu Department of Engineering Mechanics State Key Laboratory of Structural Analysis for Industrial EquipmentDalian University of TechnologyDalian116023China International Research Center for Computational Mechanics Dalian University of TechnologyDalian116023China DUT-BSU Joint Institute Dalian University of TechnologyDalian116023China Department of Automotive Engineering Tongji UniversityShanghai201804China *** SeattleWA98109USA School of Automotive Engineering Dalian University of TechnologyDalian116023China

Elastography is a non-invasive medical imaging technique to map the spatial variation of elastic properties of soft *** quality of reconstruction results in elastography is highly sensitive to the noise induced by imaging measurements and *** address this issue,we propose a deep learning(DL)model based on conditional Generative Adversarial Networks(cGANs)to improve the quality of nonhomogeneous shear modulus *** train this model,we generated a synthetic displacement field with finite element simulation under known nonhomogeneous shear modulus *** the simulated and experimental displacement fields are used to validate the proposed *** reconstructed results demonstrate that the DL model with synthetic training data is able to improve the quality of the reconstruction compared with the well-established optimization ***,we emphasize that our DL model is only trained on synthetic *** might provide a way to alleviate the challenge of obtaining clinical or experimental data in ***,this work addresses several fatal issues in applying the DL technique into elastography,and the proposed method has shown great potential in improving the accuracy of the disease diagnosis in clinical medicine.

关键词： Nonhomogeneous elastic property distribution reconstruction deep learning finite element method inverse problem elastography conditional generative adversarial network

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Beyond surgery:Overcoming postoperative depression in cancer patients

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World Journal of Psychiatry 2024年第7期14卷 1140-1142页

作者： Shao-Ming Song Xiao Wang Hong-mei yue Rong Liu The First School of Clinical Medicine Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Faculty of Hepato-pancreato-biliary Surgery The First Medical Center of PLA General HospitalBeijing 100853China

Depression is a common occurrence among cancer patients,and it significantly impacts their clinical outcomes and quality of life,with a high incidence during anti-tumor treatment or after *** association between surgery and depression is the result of the interaction of various factors,including physio-logical,psychological,and social factors,all of which are intertwined and make patients susceptible to depression after surgical *** depression has a significant negative impact on many aspects of cancer patients,and it requires timely identification and intervention to improve the overall outcome.

关键词： Depression Surgery Tumor Anti-tumor therapy

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Discrimination of polysorbate 20 by high-performance liquid chromatography-charged aerosol detection and characterization for components by expanding compound database and library

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Journal of Pharmaceutical Analysis 2024年第5期14卷 722-732页

作者： Shi-Qi Wang Xun Zhao Li-Jun Zhang yue-mei Zhao Lei Chen Jin-Lin Zhang Bao-Cheng Wang Sheng Tang Tom Yuan Yaozuo Yuan mei Zhang Hian Kee Lee Hai-Wei Shi Jiangsu Institute for Food and Drug Control Nanjing210019China School of Pharmacy China Pharmaceutical UniversityNanjing211112China School of Pharmacy Nanjing University of Chinese MedicineNanjing210046China Chinese Pharmacopoeia Commission Beijing100061China Nanjing Well Pharmaceutical Group Co. Ltd.Nanjing210018China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiangJiangsu212003China University of Massachusetts Amherst Amherst01003USA Department of Chemistry National University of SingaporeSingapore117543Singapore

Analyzing polysorbate 20(PS20)composition and the impact of each component on stability and safety is crucial due to formulation variations and individual *** similar structures and polarities of PS20 components make accurate separation,identification,and quantification *** this work,a high-resolution quantitative method was developed using single-dimensional high-performance liquid chromatography(HPLC)with charged aerosol detection(CAD)to separate 18 key components with multiple *** separated components were characterized by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry(UHPLC-Q-TOF-MS)with an identical gradient as the HPLC-CAD *** polysorbate compound database and library were expanded over 7-time compared to the commercial *** method investigated differences in PS20 samples from various origins and grades for different dosage forms to evaluate the composition-process ***-Q-TOF-MS identified 1329 to 1511 compounds in 4 batches of PS20 from different *** method observed the impact of 4 degradation conditions on peak components,identifying stable components and their tendencies to ***-CAD and UHPLC-Q-TOF-MS results provided insights into fingerprint differences,distinguishing quasi products.

关键词： Polysorbate 20 Component Database Discrimination Degradation

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C-F insertion reaction sheds new light on the construction of fluorinated compounds

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Chinese Chemical Letters 2024年第8期35卷 163-169页

作者： Dong-Sheng Deng Su-Qin Tang Yong-Tu Yuan Ding-Xiong Xie Zhi-Yuan Zhu yue-mei Huang Yun-Lin Liu Henan Key Laboratory of Function-Oriented Porous Materials and College of Chemistry and Chemical EngineeringLuoyang Normal UniversityLuoyang 471934China School of Chemistry and Chemical Engineering Guangzhou UniversityGuangzhou 510006China Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

The atom-economical C-F insertion chemistry is emerged as a promising technology for the synthesis of various fluorinated scaffolds,which have wide applications both in the academic and the industrial *** past three years have witnessed rapid developments in this *** highlight provides an overview on the evolution according to the fluorinating agents used.

关键词： C-F insertion Benzyl fluoride Acyl fluoride gem-Difluorocyclopropane Fluorinated scaffold

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Burdened breaths:The influence of depression on obstructive sleep apnea

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World Journal of Psychiatry 2024年第9期14卷 1411-1414页

作者： Xiao Wang Shao-Ming Song Hong-mei yue The First School of Clinical Medicine Lanzhou UniversityLanzhou 730000Gansu ProvinceChina

Depression and metabolic syndrome could exacerbate the risks of the other,leading to a series of severe coexisting *** notable comorbidity that must be mentioned is obstructive sleep apnea(OSA).Current studies suggested that depression increases susceptibility to *** the prevalence of depression rises,it becomes critical to prevent and manage its complications or comorbidities,including *** models,non-invasive electroencephalogram moni-toring,genetic research,and other promising technologies are being applied to the prevention,diagnosis,and personalized treatment of depression and OSA.

关键词： Depression Obstructive sleep apnea Metabolic syndrome Prevalence Risk factor

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我国核安全法治保障制度的图景、困境与前景 ——基于总体国家安全观的探讨

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河北法学 2024年第5期42卷 145-163页

作者：岳树梅王蒙西南政法大学国际法学院重庆401120

在迈向高质量发展与实现双碳目标进程中核能优势明显。世界低碳能源发展势头与各国增进能源安全的迫切需求,催生了大力开发核能的趋势。为有效因应“双碳”目标的实现、强化本国能源安全并提升我国在核能领域的话语权,在总体国家安全观... 详细信息

在迈向高质量发展与实现双碳目标进程中核能优势明显。世界低碳能源发展势头与各国增进能源安全的迫切需求,催生了大力开发核能的趋势。为有效因应“双碳”目标的实现、强化本国能源安全并提升我国在核能领域的话语权,在总体国家安全观的视阈下审视我国核安全保障领域的法律规范供给图景及面临的困境,提出应秉承统筹国内安全与国际安全、协调本国安全与共同安全的理念,借助智能化技术手段构筑穿透式的核安全风险防范与应对机制,着力从透明度与回应性、权威性与公信力的维度提升本国核安全法治保障水准。此外,多渠道多层次地推进国际合作来示范与引领核能安全有序发展,在核能领域进一步推动发展和安全深度融合,更好地发挥核能造福人类的潜力。

关键词：核安全共同安全法治保障透明度回应性

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女性尿道旁腺癌超声表现1例

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中华超声影像学杂志 2024年第6期33卷 540-542页

作者：梅乐黄颖茵过新民广东医科大学第一临床医学院湛江524023 广东医科大学广州市红十字医院超声医学科广州510220

患者女,54岁,因"排尿不适、尿道口滴血1年余,加重2个月"入院。1年前无明显诱因发现尿道口滴血,量少,1~2滴,棕褐色,间断伴有尿频、排尿困难等不适,2个月前症状加重至广东医科大学广州市红十字医院就诊。既往史、个人史、家族史无特殊。... 详细信息

患者女,54岁,因"排尿不适、尿道口滴血1年余,加重2个月"入院。1年前无明显诱因发现尿道口滴血,量少,1~2滴,棕褐色,间断伴有尿频、排尿困难等不适,2个月前症状加重至广东医科大学广州市红十字医院就诊。既往史、个人史、家族史无特殊。体格检查:经阴道前壁触及肿物,大小约为30 mm×30 mm×30 mm,质韧,无明显压痛,边界不能清晰触及。实验室检查:尿常规中白细胞1+,潜血2+,白细胞85个/μl,红细胞132个/μl;血常规、粪常规+潜血、肝肾功能以及肿瘤标志物甲胎蛋白、癌胚抗原、糖类抗原125、糖类抗原19-9、糖类抗原72-4均未见明显异常,总前列腺特异性抗原(tPSA)<0.006μg/L,游离前列腺特异性抗原(fPSA)<0.010μg/L。

关键词：红十字医院糖类抗原125 游离前列腺特异性抗原明显压痛阴道前壁粪常规潜血癌胚抗原

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Milestone progress of the HEPS booster commissioning

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Nuclear Science and Techniques 2024年第1期35卷 170-177页

作者： yue-mei Peng Jian-She Cao Jin-Hui Chen Hai-Yi Dong Ping He Yi Jiao Ling Kang Wen Kang Jian Li Jing-Yi Li Guo-Ping Lin Fang Liu Feng-Li Long Cai Meng Xin Qi Hua-Min Qu Yan-Feng Sui Sheng Wang Gang Xu Qiang Ye Jing Zhang Pei Zhang Wei-Min Pan Key Laboratory of Particle Acceleration Physics and Technology Institute of High Energy PhysicsChinese Academy of Sciences19B Yuquan RoadShijingshan DistrictBeijing 100049China University of the Chinese Academy of Sciences 19A Yuquan RoadShijingshan DistrictBeijing 100049China

The high-energy photon source(HEPS)is the first fourth-generation synchrotron light source facility in *** HEPS injector consists of a linear accelerator(Linac)and a full energy *** booster captures the electron beam from the Linac and increases its energy to the value required for the storage *** full-energy beam could be injected to the storage ring directly or after“high-energy accumulation.”On November 17,2023,the key booster parameters successfully reached their corresponding target *** milestone results were achieved based on numerous contributions,including nearly a decade of physical design,years of equipment development and installation,and months of beam *** measured at the extraction energy of 6 GeV,the averaged beam current and emittance reached 8.57 mA with 5 bunches and 30.37 nm rad with a single-bunch charge of 5.58 nC,compared with the corresponding target values of 6.6 mA and 35 nm rad,*** paper presents the physical design,equipment development,installation,and commissioning process of the HEPS booster.

关键词： High energy photon source Booster Beam commissioning

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地方数据治理与数字内容出口

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中国工业经济 2024年第5期 79-96页

作者：周念利于美月孟克对外经济贸易大学中国WTO研究院对外经济贸易大学国家(北京)对外开放研究院

数字内容贸易兼具文化、经济和科技等多重属性,是推动中国数字贸易增长的新动能。作为“数据密集型”贸易形态,数字内容贸易发展与数据治理水平休戚相关。近年来,地方政府围绕数据治理展开了积极探索,主要包括:在捍卫安全底线基础上敦... 详细信息

数字内容贸易兼具文化、经济和科技等多重属性,是推动中国数字贸易增长的新动能。作为“数据密集型”贸易形态,数字内容贸易发展与数据治理水平休戚相关。近年来,地方政府围绕数据治理展开了积极探索,主要包括:在捍卫安全底线基础上敦促数据跨境便利的“跨境流动治理”,激发数据要素活力的“交易流通治理”和促进公共数据应用开发的“开放共享治理”。本文整理了2014—2021年67个地级市发布的数据治理相关政策文件,利用文本分析方法对地方数据治理水平进行量化。本文基于***数据库,计算出中国企业层面数字内容App的出口数据,并深入探讨地方数据治理对辖区内企业数字内容出口的影响。研究发现,地方数据治理有助于推动企业数字内容出口,且影响程度因企业规模、数字内容种类和质量、数据治理举措类型以及中国与目标国规制融合程度的不同而有所差异。地方数据治理对数字内容出口的提升作用是通过“降低数据跨境合规和信息获取成本”“提升企业创新水平”和“推动数据密集型产业集聚”实现的。本文的研究结论为地方政府从提升数据治理水平出发推动中国数字内容贸易发展提供了政策启示。

关键词：地方数据治理数字内容出口政策文本分析

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数字出版中朝鲜语标记偏误分析——以朝鲜语微信公众号的标题为中心

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中国朝鲜语文 2024年第3期 79-87页

作者：金美月延边教育出版社

随着移动互联网的快速发展和智能手机的大众化,APP和微信公众号成为数字出版的主要平台。因此通过微信公众号等数字出版接触语言的机会越来越多,数字出版也需要正确规范使用语言。本文通过最近朝鲜语微信公众号标题中出现的偏误,了解朝... 详细信息

随着移动互联网的快速发展和智能手机的大众化,APP和微信公众号成为数字出版的主要平台。因此通过微信公众号等数字出版接触语言的机会越来越多,数字出版也需要正确规范使用语言。本文通过最近朝鲜语微信公众号标题中出现的偏误,了解朝鲜语的使用情况,分析偏误原因,以助益朝鲜语的正确使用和传播。

关键词：数字出版朝鲜语标记偏误

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