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海底微生物燃料电池碳毡阴极氨气改性及其电化学性能

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材料开发与应用 2020年第4期35卷 69-75页

作者：李佳李洋毛楚儒赵鸿浩郝耀康侯少鑫宰学荣付玉彬中国海洋大学材料科学与工程学院山东青岛266100 中国海洋大学化学化工学院山东青岛266100

在不同温度(650℃、800℃、950℃)下对碳毡阴极进行氨气热处理,比较改性前后海底微生物燃料电池(MSMFCs)阴极的电化学性能.其中950℃改性阴极的电容密度(172.53 F/cm^2)是Blank组的3.03倍,交换电流密度是空白组的1.53倍,说明950℃氨气... 详细信息

在不同温度(650℃、800℃、950℃)下对碳毡阴极进行氨气热处理,比较改性前后海底微生物燃料电池(MSMFCs)阴极的电化学性能.其中950℃改性阴极的电容密度(172.53 F/cm^2)是Blank组的3.03倍,交换电流密度是空白组的1.53倍,说明950℃氨气改性后阴极的抗极化能力更高;电荷转移电阻(34.09Ω)为Blank(90.96Ω)组的0.37倍,输出功率密度(569 mW/m^2)为Blank组(337 mW/m^2)的1.69倍.故950℃氨气处理碳毡阴极具有最佳的氧还原反应速率..

关键词：海底微生物燃料电池氨气热处理氮掺杂阴极电化学性能电池性能

海底微生物燃料电池钴硫化物MOF改性阴极及其电化学性能

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材料开发与应用 2020年第4期35卷 54-61页

作者：江飞逸李铁毛楚儒郝耀康侯少鑫李洋李佳付玉彬中国海洋大学化学化工学院山东青岛266100 中国海洋大学材料科学与工程学院山东青岛266100

阴极改性是提高海底沉积物微生物燃料电池(MSMFC)输出功率的方式之一.钴硫化物MOF作为一种有效的氧还原反应催化剂,可望显著提高MSMFC阴极和电池性能.将钴硫化物MOF应用于海底微生物燃料电池阴极改性并研究其电化学性能.结果表明,钴硫化... 详细信息

阴极改性是提高海底沉积物微生物燃料电池(MSMFC)输出功率的方式之一.钴硫化物MOF作为一种有效的氧还原反应催化剂,可望显著提高MSMFC阴极和电池性能.将钴硫化物MOF应用于海底微生物燃料电池阴极改性并研究其电化学性能.结果表明,钴硫化物MOF改性阴极具有最佳的抗极化能力、最高的反应动力学活性和最高的输出功率.其交换电流密度为11.11mA/m^2,是空白碳毡的2.14倍;其最大输出功率密度是8.27 mW/m^2,约是空白碳毡阴极的5倍.

关键词：海底微生物燃料电池阴极改性钴硫化物MOF 电化学性能

Membrane-camouflaged supramolecular nanoparticles for co-delivery of chemotherapeutic and molecular-targeted drugs with siRNA against patient-derived pancreatic carcinoma

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Acta Pharmaceutica Sinica B 2022年第8期12卷 3410-3426页

作者： Honglin Tang Yanan Xue Bowen Li Xiaojie Xu fu Zhang Jiajing Guo Qijun Li Tingting Yuan Yuan Chen yubin Pan Yuan Ping Da Li Department of Medical Oncology Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310058China College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China Department of Hepatobiliary and Pancreatic Surgery the First Affiliated HospitalZhejiang UniversityHangzhou 310003China

Pancreatic cancer remains one of the most lethal malignancies worldwide. The combination of the first-line standard agent gemcitabine(GEM) with the molecular-targeted drug erlotinib(Er) has emerged as a promising strategy for pancreatic cancer treatment. However, the clinical benefit from this combination is still far from satisfactory due to the unfavorable drug antagonism and the fibrotic tumor microenvironment. Herein, we propose a membrane-camouflaged dual stimuliresponsive delivery system for the co-delivery of GEM and Er into pancreatic cancer cells and tissues to block the antagonism, as well as reshapes profibrotic tumor microenvironment via simultaneous delivery of small interference RNA(siRNA) for synergistic pancreatic cancer treatment. This “all-in-one”delivery system exhibits sensitive GSH and pH-dependent drug release profiles and enhances the inhibitory effects on the proliferation and migration of tumor cells in vitro. Excitingly, the systemic injection of such a biomimetic drug co-delivery system not only resulted in superior inhibitory effects against orthotopic pancreatic tumor and patient-derived tumor(PDX), but also greatly extended the survival rate of tumor-bearing mice. Our findings provide a promising therapeutic strategy against pancreatic cancer through the enhanced synergistic effect of target therapy, chemotherapy and anti-fibrotic therapy, which represents an appealing way for pancreatic cancer treatment.

关键词： Chemotherapy Target therapy siRNA Nanomedicine Hybrid membrane Drug antagonism Pancreatic carcinoma Patient-derived tumor

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氧化物靶材的制备及研究进展

材料研究与应用 2022年第3期16卷 362-368页

作者：付钰斌宁洪龙邹文昕吴振宇张康平郭晨潇刘丁荣侯明玥姚日晖彭俊彪华南理工大学发光材料与器件国家重点实验室高分子光电材料与器件研究所广东广州510641

氧化物靶材是一种关键性镀膜基材,主要用于磁控溅射制备TFT薄膜,并将其应用于晶体管等器件中透明电极、半导体沟道层,同时也广泛应用于显示面板领域。为满足高性能器件对薄膜的要求,氧化物靶材逐渐向高致密、大尺寸、异形化方向发展。... 详细信息

氧化物靶材是一种关键性镀膜基材,主要用于磁控溅射制备TFT薄膜,并将其应用于晶体管等器件中透明电极、半导体沟道层,同时也广泛应用于显示面板领域。为满足高性能器件对薄膜的要求,氧化物靶材逐渐向高致密、大尺寸、异形化方向发展。以显示行业中氧化物靶材作为重点,介绍了氧化物靶材制备流程,主要从素坯成型、烧结工艺两个角度对氧化物靶材进行总结,分析了烧结工艺对靶材参数与溅射薄膜电阻率、光学透射率及粗糙度等方面的影响,最后阐述了国内外氧化物靶材市场的现状及发展趋势。

关键词：氧化物溅射靶材成型烧结薄膜

维普期刊数据库博看期刊

functional characterization of disease/comorbidity-associated IncRNA

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Quantitative Biology 2021年第4期9卷 411-425页

作者： Jing Tang Yongheng Wang Jianbo fu Xianglu Wu Zhijie Han Chuan Wang Maiyuan Guo Yingxiong Wang yubin Ding Bo Yang Feng Zhu College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China College of Basic Medicine Chongqing Medical UniversityChongqing 400016China Joint International Research Laboratory of Reproductive and Development Department of Reproductive BiologySchool of Public HealthChongqing Medical UniversityChongqing 400016China

Background:functional characterization of the long noncoding RNAs(IncRNAs)in disease attracts great attention,which results in a limited number of experimentally characterized *** major problems underlying the lack of experimental verifications are considered to come from the significant false-positive assignments and extensive genetic-heterogeneity of *** problems are even worse when it comes to the functional characterization in comorbidity(simultaneous/sequential presence of multiple diseases in a patient,and showing much wider prevalence,poorer treatment-response and longer illness-course than a single disease).Methods:Herein,FCCLnc was developed to characterize IncRNA function by(1)integrating diverse SNPs that were associated with 193 diseases standardized by International Classification of Diseases(ICD-11),(2)condition-specific expression of IncRNAs,(3)weighted correlation network of IncRNAs and protein-coding neighboring ***:FCCLnc can characterize IncRNA function in both disease and comorbidity by not only controlling false discovery but also tolerating their disease ***,FCCLnc can provide interactive visualization and full download of IncRNA-centered co-expression ***:In summary,FCCLnc is unique in characterizing IncRNA function in diverse diseases and comorbidities and is highly expected to emerge to be an indispensable complement to other available *** is accessible at https://***/fcclnc/.

关键词： comorbidity long noncoding RNA functional characterization disease-associated SNPs guilt-by-association

Microecology-turbidity toxin theory: correlation between helicobacter pylori infection and manifestation of tongue and gastroscopy

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Journal of Traditional Chinese Medicine 2022年第3期42卷 458-462页

作者： WANG Jin WANG Huijie XIAO Ying GUO Jiaxuan ZHAO yubin Department of Integrated Chinese and Western Medicine Hebei University of Chinese MedicineShijiazhuang 050000China the Traditional Chinese Medicine Hospital of Shijiazhuang Affiliated to Hebei University of Chinese Medicine Shijiazhuang 050000China Department of Bioengineering School of Chemical EngineeringShijiazhuang UniversityShijiazhuang 050000China The Traditional Chinese Medicine Hospital of Shijiazhuang Affiliated to Hebei University of Chinese Medicine Shijiazhuang 050000HebeiChina Shijiazhuang People's Hospital Shijiazhuang 050000China

OBJECTIVE:To clarify the relationship between helicobacter pylori(Hp)infection,tongue manifestation and gastroscopic manifestation,and explore the mechanism of action of“oral-gastric microecology”in the occurrence and development of stomach-related ***:A total of 1100 patients were divided into Hp positive group and Hp negative group according to 13 C breath test *** tongue manifestation materials from patients were collected to make tongue printing slides for morphological observation of exfoliative cells from tongue coating,and electronic gastroscopy was performed on the patients and the data was ***:Hp infection rate was about 45.95%;and the greasy coating was mostly observed in Hp positive group(63.14%,Pyellow coating>white coating>white greasy *** gastric mucosal roughness and mucosal hematoplastic plaques in the two groups were more common in the Hp positive group(P<0.05).There was a significant difference in the granular subgroup and in the rough mucosal group(P<0.05).CONCLUSIONS:Hp infection is more commonly observed in yellow greasy coating,and this can be used as a reference for Traditional Chinese Medicine in determining whether it is Hp infection or *** granule roughness,hyperemia,and oral Hp showed association with Hp infection in the stomach and interacted with micro-ecological environment that is composed of the oral cavity.

关键词： Helicobacter pylori abnormal tongue presentations gastroscopy breath tests micro-ecology turbidity toxin theory

Small-signal modelling and stability analysis of grid-following and grid-forming inverters dominated power system

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Global Energy Interconnection 2023年第3期6卷 363-374页

作者： Yaran Li Long fu Qiang Li Wei Wang yubin Jia Zhao Yang Dong State Grid Jiangsu Electric Power Research Institute Nanjing 211103P.R.China NARI Group Corporation(State Grid Electric Power Research Institute) Nanjing 211106P.R.China School of Automation Southeast UniversityNanjing 210096P.R.China School of Electrical and Electronics Engineering Nanyang Technological University 639798Singapore

In this paper,the explicit state-space model for a multi-inverter system including grid-following inverter-based generators(IBGs)and grid-forming IBGs is developed by the two-level component connection method(CCM),which modularized inverter control blocks at the primary level and IBGs at the secondary *** on the comprehensive state-space model representing full order of system dynamics,eigenvalues of the overall system are thoroughly analyzed,identifying potential adverse impacts of not only grid-following inverters,but also grid forming inverters on the system small-signal stability,with the underlying principle of oscillations also *** and simulation results validate effectiveness of the proposed methodology on IEEE benchmarking 39-bus system.

关键词： Grid-following control Grid-forming control State-space modelling Inverter-driven oscillations

In situ study on medium-range order evolution during the polyamorphous phase transition in a Pd-Ni-P nanostructured glass

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Journal of Materials Science & Technology 2022年第30期125卷 145-156页

作者： Shu fu Sinan Liu Jiacheng Ge Junjie Wang Huiqiang Ying Shangshu Wu Mengyang Yan Li Zhu yubin Ke Junhua Luan Yang Ren Xiaobing Zuo Zhenduo Wu Zhen Peng Chain-Tsuan Liu Xun-Li Wang Tao Feng Si Lan Herbert Gleiter Institute of Nanoscience School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing 210094P.R.China Department of Physics City University of Hong Kong83 Tat Chee AvenueKowloonHong Kong SARP.R.China Spallation Neutron Source Science Center Dongguan 523803P.R.China Department of Materials Science and Engineering City University of Hong KongHong KongP.R.China X-ray Science Division Argonne National LaboratoryLemontIllinois 60439USA Center of Neutron Scattering and Applied Physics City University of Hong Kong Dongguan Research InstituteDongguan 52300P.R.China School of Materials Science and Engineering Jiangsu UniversityZhenjiang 212013P.R.China Center of Neutron Scattering City University of Hong Kong Shenzhen Research Institute8 Yuexing 1st RoadShenzhen Hi-Tech Industrial ParkShenzhen 518057P.R.China

Engineering multiscale structural hierarchies in glassy alloys enable a broad spectrum of potential *** glasses were born in hierarchical structures from atomic-to-nanometer ***,the frozen-in structures in traditional metallic glasses prepared by rapid quenching techniques are challenging to ***,we show that a PdNiPbulk nanostructured glass of polyamorphous interfacial structures was prepared by inert-gas condensation with a laser evaporation source,and its multiscale structures could be ***-situ scattering experiment results reveal polyamorphous phase transitions occurred in the interfacial regions,which are accompanied by the evolution of medium-range order and the nanoscale heterogeneous structures during the condensation process of glassy nanoparticles under high pressure and the following heating ***,changes in the cluster connectivity resulting from repacking of the local ordering induced by pressure and temperature could be *** thermophysical and mechanical properties,including boson peaks,hardness,and elasticity modulus,could be changed as a function of heat-treatment *** findings would shed light on the synthesis of bulk nanostructured glassy alloys with tailorable thermodynamic and dynamical behavior as well as mechanical properties based on the understanding of metastability for polyamorphous interfacial phases.

关键词： Bulk nanostructured glasses Medium-range order Polyamorphous phase transition

Fabrication of Ni-decorated helical ribbon composite microstructure from self-assembled lipid tubule by electroless metallization

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Science China Chemistry 2006年第3期49卷 238-245页

作者： fu yubin1,2, ZHANG Lide1 & ZHENG Jiyong2 1. Institute of Solid State Physics, China Academy of Sciences, Hefei 230031, China 2. Luoyang Ship Material Research Institute, Luoyang 471039, China Institute of Solid State Physics China Academy of Sciences Hefei China Luoyang Ship Material Research Institute Luoyang China

Lipid molecules can self-assemble into a tubular structure, which is formed by tightly wound helical ribbons. Lipid tubules are utilized as a precursor to fabricate a novel Ni-decorated helical ribbon composite microstructure in a high yield by electroless deposition. The microstructure carries Ni nanoparticles on the flat face and wires at the edge of helical ribbon, in which the average size of nanoparticles is about 40―60 nm, and the wires are of a layered structure strongly correlated with a multi-bilayer structure in the lipid membrane. Compared with the tubular precursor, the Ni-decorated composite microstructure becomes short and irregular shapes due to the breakage in the deposition, and its formation is largely bound up with the tubular helical structure and the different catalytic process. Finally, the helical composite microstructure would have a potential application in the development of electric active materials.

关键词： molecular self-assembly, lipid tubule, helical ribbon, electroless deposition, nanoparticles and wires, composite microstructure.