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iCare眼压计测量小鼠眼压值与真实眼压的相关性研究

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现代生物医学进展 2011年第16期11卷 3022-3024页

作者：环梦佳袁志兰袁松涛钱朝旭罗莎莎南京医科大学江苏南京210029 江苏省人民医院江苏南京210029 南京医科大学附属第一人民医院江苏南京210029

目的:通过前房插管技术调节小鼠眼压,研究iCare眼压计测量小鼠眼压值与小鼠真实眼压之间的相关性。方法:取20只12周龄的C57BL/6J小鼠,麻醉后行前房穿刺置管,通过改变BSS液瓶高度调节其眼压。使用iCare眼压计测量其眼压值。采用SPSS软件... 详细信息

目的:通过前房插管技术调节小鼠眼压,研究iCare眼压计测量小鼠眼压值与小鼠真实眼压之间的相关性。方法:取20只12周龄的C57BL/6J小鼠,麻醉后行前房穿刺置管,通过改变BSS液瓶高度调节其眼压。使用iCare眼压计测量其眼压值。采用SPSS软件分析iCare眼压计测量值和小鼠真实眼压之间的相关性。结果:iCare眼压计测量值与真实眼压之间相差较大,较真实眼压低约54%-71%,然而两者之间遵循如下线性回归方程:真实眼压(mmHg)=3.3988×(iCare眼压计测量值)-5.6292,rZ=0.9506,P<0.05。结论:iCare眼压计测量值较小鼠真实眼压低,然而在应用线性回归公式的情况下,iCare眼压计的测量修正值可以反映小鼠实际眼压值。

关键词： iCare眼压计眼压小鼠相关性

Hafnium in Aluminum Alloys:A Review

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Acta Metallurgica Sinica(English Letters) 2016年第2期29卷 105-119页

作者： zhi-Hong Jia Hui-lan Huang Xue-Li Wang yuan Xing Qing Liu College of Materials Science and Engineering Chongqing University

Lots of the available literatures on hafnium in aluminum alloys are reviewed. The new binary Al-Hf phase diagram is simply assessed. Two ternary phase diagrams including Al-Hf-Zr and Al-Hf-Sc are accounted for, with emphasis on the aluminum rich part of the diagrams. The relationship between different structure Al3Hf and several different formation mechanisms including the probable phase transformation mechanisms is described. The continuous Al3Hf phase particles can serve as a grain refiner in the Al melt and a precipitate for controlling the grain structure of the alloy and a strengthening precipitate. A series of effects of Fe, Si, Zr, Sc and Li addition on the behavior of Al3Hf and Al alloys are given. Moreover, the effects of Hf on the microstructure and properties of Al alloys, such as hardness and creep, are reviewed. Finally, some views of Hf-containing Al alloys are summarized.

关键词： AI-Hf Phase diagram AI3Hf precipitate Microstructure Properties

Microstructure of Al-Si-Mg alloy with Zr/Hf additions during solidification and solution treatment

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Rare Metals 2019年第11期38卷 1033-1042页

作者： Hui-lan Huang zhi-Hong Jia yuan Xing Xue-Li Wang Qing Liu College of Materials Science and Engineering Chongqing University

In this study,the morphology,composition and evolution of intermetallics in Al-7Si-0.3Mg,Al-7Si-0.3Mg-0.47Hf,Al-7Si-0.3Mg-0.16 Zr and Al-7Si-0.3Mg-0.14Zr-0.44Hf alloys were characterized by optical microscope(OM),scanning electron microscope(SEM)with energy-dispersive spectrometer(EDS) and transmission electron microscope(TEM).The AlSiZr,AlSiHf and AlSiZrHf phases are formed with additions of Zr and/or Hf in base alloy during solidification,especially the AlZrHf primary *** three-dimensional morphology of the AlZrHf particle evolves from 10-polyhedron-like to compressed cube-like during *** new AlZrHf phase experiences partial dissolution after solution treatment,while the others remain in the initial *** Si contents lead to form thermally stable Zr/Hfrich precipitates in Zr/Hf-containing alloys during solution treatment,especially the nanobelt-like Si2Zr,Si2Hf and Si2(Zr,Hf) *** orientation relationships and the growth mechanism are *** finding of the work broadens the elevated temperature application of Al-Si-Mg in modern automotive aluminum engine.

关键词： Al-Si-Mg cast alloy Primary phase Solution treatment Precipitate Orientation relationships

Spectrum-effect relationship between HPLC fingerprints and bioactive components of Radix Hedysari on increasing the peak bone mass of rat

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Journal of Pharmaceutical Analysis 2019年第4期9卷 266-273页

作者： Xin-Yue Chen San-Hu Gou zhi-Qiang Shi zhi-yuan Xue Shi-lan Feng School of Pharmacy Lanzhou University

The traditional Chinese medicine of Radix Hedysari plays an important role in invigorating gas for ascending, benefiting blood for promoting production of fluid, and promoting circulation for removing obstruction in collaterals, which is consistent with the principle of treatment for osteoporosis. This study is designed to investigate the bioactive components on increasing peak bone mass (PBM) by exploring the spectrum-effect relationship between chromatography fingerprints and effect. Multiple indicators are selected to evaluate the pharmacological activity. In fingerprints, 21 common peaks are obtained, five of which are identified. Furthermore, gray relational analysis (GRA) is a quantitative method of gray system theory and is used to describe the correlation degree of common peaks and pharmacological activities with relational value. 21 components are then divided into three different regions, of which ononin and calycosin play an extremely significant role in increasing PBM. In addition, factor analysis and hierarchical cluster analysis (HCA) are used to screen the optimal producing area for Radix Hedysari. This provides a comprehensive and efficient method to improve the quality evaluation of Radix Hedysari, confirming the bioactive components for PBM-enhancement and further develop its medicinal value.

关键词： Factor analysis Gray relational analysis Hierarchical cluster analysis Peak bone mass Radix Hedysari Spectrum-effect relationship

Analysis of Genetic Similarity for Improved Japonica Rice Varieties from Different Provinces and Cities in China

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Agricultural Sciences in China 2010年第8期9卷 1093-1100页

作者： SHU Ai-ping ZHANG yuan-yuan CAO Gui-lan LU Qin ZHANG San-yuan HAN Long-zhi Institute of Crop Sciences Chinese Academy of Agricultural Sciences/National Key Facility for Crop Gene Resources and Genetic Improvement (NFCRI)/Key Laboratory of Crop Germplasm Resources and Utilization Ministry of Agriculture Beijing 100081 P.R. China College of Crop Science Fujian Agricultural and Forestry University Fuzhou 350002 P.R. China Rice Research Institute Jiangxi Academy of Agricultural Sciences Nanchang 330200 P.R.China Institute of Rice Research Jilin Academy of Agricultural Sciences Gongzhuling 136100 P.R.China

To provide a genetic basis for japonica rice breeding, the genetic similarity and cluster of 139 accessions of improved japonica rice varieties from 12 provinces and cities of China were analyzed using 34 SSR markers. Totally 198 alleles were detected among these improved japonica rice varieties with the average number of alleles per pair of primers was 5.3235. RM320, RM531, RM1, RM286, and RM336 showed more alleles, which were 15, 12, 11, 9, and 9, respectively. RM320, RM336, RM286 and RM531 showed higher genetic diversity indexes; which were 2.3324, 2.0292, 1.8996, and 1.7820, respectively. The range of genetic similar index among improved japonica rice varieties from different provinces was from 0.321 to 0.914, with the average of 0.686. There was a high genetic similarity among improved japonica rice varieties from Heilongjiang, Jilin, Liaoning, Ningxia, and Yunnan, which were located in similar latitude or similar ecological environment, while there was a low genetic similarity between improved japonica rice varieties from Guizhou and Jiangsu, and other provinces which were located in more different latitudes and ecological environments. The markers of RM320, RM531, RM1, RM286, and RM336 fit to be used in analysis of genetic diversity for improved japonica rice variety. The genetic similarity among improved japonica rice varieties from different provinces was closely associated with genetic basis of parents, and was also correlated with latitude and ecological environment where the varieties were bred.

关键词： improved japonica rice variety genetic similarity genetic basis of parent ecological and climatic environment SSR marker

Tautological Integrals on Symmetric Products of Curves

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Acta Mathematica Sinica,English Series 2016年第8期32卷 901-910页

作者： zhi lan WANG Institute of Mathematics Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 P. R. China

We propose a conjecture on the generating series of Chern numbers of tautological bundles on symmetric products of curves and establish the rank 1 and rank -1 case of this conjecture. Thus we compute explicitly the generating series of integrals of Segre classes of tautological bundles of line bundles on curves, which has a similar structure as Lehn＇s conjecture for surfaces.

关键词： Hilbert schemes tautological sheaves

The synthesis and biological evaluation of a series of novel 2-COOC_2H_5/COONa substituted 1,5-benzothiazepine derivatives as antimicrobial agents

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Chinese Chemical Letters 2009年第6期20卷 660-662页

作者： Ping Zhang lan zhi Wang Hui Shu Wu Jia Ming lan yuan Li Yong Xiang Wang The College of Chemistry & Material Science Hebei Normal University Shijiazhuang 050016 China Department of Pathogenic Biology Hebei Medical University Shijiazhuang 050017 China

A series of novel 1,5-benzothiazepine derivatives containing COOC2H5/COONa groups at the C（2）-position were synthesized and evaluated for their antifungal and antibacterial activities by both disc diffusion and minimal inhibition concentration （MIC） methods. Most of the compounds have been shown to have moderate to good antibacterial activity against S. aureus, S. epidermidis and excellent antifungal activity against C. albicans.

关键词： 1,5-Benzothiazepine Antifungal Antibacterial activities

CAVITATION CONTROL BY AERATION AND ITS COMPRESSIBLE CHARACTERISTICS

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Journal of Hydrodynamics 2006年第4期18卷 499-504页

作者： DONG zhi-yong SU Pei-lan School of Civil Engineering and Architecture Zhejiang University of Technology Hangzhou 310032 China School of Forestry Shanxi Agricultural University Taigu 030801 China

This paper presents an experimental investigation and a theoretical analysis of cavitation control by aeration and its compressible characteristics at the flow velocity V=20m/s-50m/s. Pressure waveforms with and without aeration in cavitation region were measured. The variation of compression ratio with air concentration was described, and the relation between the least air concentration to prevent cavitation erosion and flow velocity proposed based on our experimental study. The experimental results show that aeration remarkably increases the pressure in cavitation region, and the corresponding pressure wave exhibits a compression wave/shock wave. The pressure increase in cavitation region of high-velocity flow with aeration is due to the fact that the compression waves/shock wave after the flow is aerated. The compression ratio increases with air concentration rising. The relation between flow velocity and least air concentration to prevent cavitation erosion follows a semi-cubical parabola. Also, the speed of sound and Mach number of high-velocity aerated flow were analyzed.

关键词： cavitation control by aeration compression wave/shock wave least air concentration speed of sound compression ratio

Mechanistic Analysis of AKT1 Regulation by the CBL-CIPK-PP2CA Interactions

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Molecular Plant 2011年第3期4卷 527-536页

作者： Wen-zhi lan Sung-Chul Lee Yu-Fen Che yuan-Qing Jiang Sheng Luan Department of Plant and Microbial Biology University of California Berkeley CA 94720 USA School of Biological Sciences (BK21 program) Chung-Ang University Seoul.156-756 Korea College of Food Science and Nutritional Engineering China Agricultural University Beijing 100083 China DBST-WCU Program Chonnam National University-Gwangju 500-757 Korea

Arabidopsis K＋ transporter I （AKT1） participates in K＋ uptake in roots, especially under Iow-K conditions. We recently identified a Ca2＋ signaling pathway consisting of multiple calcineurin B-like calcium sensors （CBLs） and multiple target kinases （CBL-interacting protein kinases or CIPKs） that phosphorylate and activate AKT1, whereas a specific PP2C-type phosphatase inactivates CIPK-dependent AKT1 activity. In this study, we analyzed the interactions between PP2Cs and the CBL-CIPK pathway and found previously unsuspected mechanisms underlying the CBL-CIPK-PP2C signaling processes. The interaction between the CIPKs and PP2Cs involves the kinase domain of the CIPK component, in addition to the protein phosphatase interacting motif （PPI） in the regulatory domain. Furthermore, specific CBLs physically interact with and inactivate PP2C phosphatases to recover the CIPK-dependent AKT1 channel activity. These findings provide fur- ther insights into the signaling network consisting of CBL-CIPK-PP2C interactions in the activation of the AKT1 channel.

关键词： Abscisic acid Arabidopsis environmental stress K+ uptake.