检索结果-南通市图书馆

Regulation of the inflammasome adaptor ASC mediated singling and arthritis diseases

在线全文

学校读者我要写书评

暂无评论

Regulation of the inflammasome adaptor ASC mediated singling...

Correlation between the rock mass properties and maximum horizontal stress:A case study of overcoring stress measurements

第十届全国免疫学学术大会

作者： Dakang Xu hangjie Ying Xiaofang Li Liyun Shi yuan h yang Institute of Ageing Research Hangzhou Normal University School of Medicine

Rheumatoid arthritis is a chronic autoinflammatory disease. Interlenkin-1b(IL-1b) is a key factor of cartilage destruction in rheumatic disease, but the regulation of IL-1b in rheumatoid arthritis is limited by the absence of suitable mouse models of the disease. here, we show that ASC, a component of the inflammasome complex promotes IL-1b secretion and modulates synovial inflammation in the K/Bx N serum transfer induced arthritis models. That it crucially relies on the ASC inflammasome and IL-1b receptor signaling, but that regulation is unknown. In the macrophages, when we lacking PLZF has decreased the protein expression level of the inflammasome adaptor ASC, in contrast the pro IL-1b is not altered. As a result, PLZF deficiency in the macrophages significantly reduced ASC inflammasome-mediated caspase-1 activation, pyroptosis and IL-1 b secretion by number of NLRP3 stimuli. Importantly, decreased ASC inflammasome activation limited the pathology of rheumatoid arthritis was found in the PLZF deficiency mice. These results reveal PLZF as a novel regulator of ASC inflammasome mediated capase-1 activation and IL-1b secretion, and subsequently promote rheumatoid arthritis associated inflammasome disease and cartilage destruction.

关键词： inflammasome

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 39-48页

作者： Peng Li Meifeng Cai Shengjun Miao yuan Li Yu Wang Key Laboratory of Ministry of Education for Efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Coal Resources and Safe Mining China University of Mining and TechnologyXuzhou 221116China

Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress *** investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution *** results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with *** is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and ***,there is no obvious relationship between the rock quality designation(RQD)and *** maximum horizontal stress σ_(h) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same *** addition,the overall change trend of σ_(h) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_h and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.

关键词： overcoring stress measurements elastic modulus Poisson's ratio rock quality designation maximum horizontal stress fuzzy identification

在线全文

学校读者我要写书评

暂无评论

论“心即理”视域下翻译学天人合一的意义观

外语学刊 2025年第1期 86-91页

作者：杨镇源电子科技大学外国语学院成都611731

西方翻译学呈现出两种基本意义观:一是在柏拉图主义的笼罩下,将形而上的绝对意义视作完美而不可触及的彼岸,将形而下的相对阐释视作现实却又充满缺憾的此岸,并认为后者只能是对前者的拙劣模仿;二是在解构主义的影响下,将绝对意义和相对... 详细信息

西方翻译学呈现出两种基本意义观:一是在柏拉图主义的笼罩下,将形而上的绝对意义视作完美而不可触及的彼岸,将形而下的相对阐释视作现实却又充满缺憾的此岸,并认为后者只能是对前者的拙劣模仿;二是在解构主义的影响下,将绝对意义和相对阐释同归于虚无。前者以“尊天抑人”的态势陷入天人二分的意义观,在一定程度压抑人本主义精神,后者以“毁天灭人”的态势陷入天人两空的意义观,因而引发虚无主义困境。在新儒家心学思想的“心即理”视域下,翻译学能够走出上述两种思维定势,促使译者立足本心,打通道枢,实现绝对意义和相对阐释的圆融统一,以“顺天应人”的态势成就天人合一的意义观。较之西方翻译学的两种意义观,它不仅凸显译者心性的关键作用,强化人本主义精神,还将本心作为意义的稳固立足点,避免虚无主义困境。这体现出心学思想对于翻译学意义观建构的独特价值,也为中国传统哲学思想在当代翻译学的应用提供了一个值得关注的学术增长点。

关键词：翻译学意义观心即理本心天人合一

Locally Enhanced Flow and Electric Fields Through a Tip Effect for Efficient Flow‑Electrode Capacitive Deionization

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 1-17页

作者： Ziquan Wang Xiangfeng Chen yuan Zhang Jie Ma Zhiqun Lin Amor Abdelkader Maria‑Magdalena Titirici Libo Deng College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Research Center for Environmental Functional Materials College of Environmental Science and EngineeringTongji University1239 Siping RoadShanghai 200092People’s Republic of China Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117585Singapore Department of Engineering Faculty of Science and TechnologyBournemouth UniversityTalbot CampusFern BarrowPooleEngland BH125BBUK Institut de Chimie de Nice UniversitéCôte d’AzurUMR CNRS 727228 Av.Valrose06108 NiceFrance Department of Chemical Engineering Imperial College LondonSouth Kensington CampusExhibition RdLondon SW72AZUK

Low-electrode capacitive deionization(FCDI)is an emerging desalination technology with great potential for removal and/or recycling ions from a range of ***,it still suffers from inefficient charge transfer and ion transport kinetics due to weak turbulence and low electric intensity in flow electrodes,both restricted by the current ***,a new tip-array current collector(designated as T-CC)was developed to replace the conventional planar current collectors,which intensifies both the charge transfer and ion transport *** effects of tip arrays on flow and electric fields were studied by both computational simulations and electrochemical impedance spectroscopy,which revealed the reduction of ion transport barrier,charge transport barrier and internal *** the voltage increased from 1.0 to 1.5 and 2.0 V,the T-CC-based FCDI system(T-FCDI)exhibited average salt removal rates(ASRR)of 0.18,0.50,and 0.89μmol cm^(-2) min^(-1),respectively,which are 1.82,2.65,and 2.48 folds higher than that of the conventional serpentine current collectors,and 1.48,1.67,and 1.49 folds higher than that of the planar current ***,with the solid content in flow electrodes increased from 1 to 5 wt%,the ASRR for T-FCDI increased from 0.29 to 0.50μmol cm^(-2) min^(-1),which are 1.70 and 1.67 folds higher than that of the planar current ***,a salt removal efficiency of 99.89%was achieved with T-FCDI and the charge efficiency remained above 95%after 24 h of operation,thus showing its superior long-term stability.

关键词： Flow-electrode Capacitive deionization Current collector Tip effect Desalination

Exploration of Gas‑Dependent Self‑Adaptive Reconstruction Behavior of Cu_(2)O for Electrochemical CO_(2)Conversion to Multi‑Carbon Products

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第3期17卷 280-296页

作者： Chaoran Zhang Yichuan Gu Qu Jiang Ziyang Sheng Ruohan Feng Sihong Wang haoyue Zhang Qianqing Xu Zijian yuan Fang Song State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Structural reconstruction of electrocatalysts plays a pivotal role in catalytic performances for CO_(2)reduction reaction(CO_(2)RR),whereas the behavior is by far superficially ***,we report that CO_(2)accessibility results in a universal self-adaptive structural reconstruction from Cu_(2)O to Cu@CuxO composites,ending with feeding gas-dependent microstructures and catalytic *** CO_(2)-rich atmosphere favors reconstruction for CO_(2)RR,whereas the CO_(2)-deficient one prefers that for hydrogen evolution *** the assistance of spectroscopic analysis and theoretical calculations,we uncover a CO_(2)-induced passivation behavior by identifying a reductionresistant but catalytic active Cu(I)-rich amorphous layer stabilized by*CO ***,we find extra CO production is indispensable for the robust production of *** inverse correlation between durability and FECO/FEC2h4 is disclosed,suggesting that the selfstabilization process involving the absorption of*CO intermediates on Cu(I)sites is essential for durable *** by this insight,we design hollow Cu_(2)O nanospheres for durable and selective CO_(2)RR electrolysis in producing *** work recognizes the previously overlooked passivation reconstruction and self-stabilizing behavior and highlights the critical role of the local atmosphere in modulating reconstruction and catalytic processes.

关键词： CO_(2)reduction reaction Electrocatalysts Cu_(2)O Reconstruction Self-adaptive electrocatalysis

Co/Co_(7)Fe_(3)heterostructures with controllable alloying degree on carbon spheres as bifunctional electrocatalyst forrechargeable zinc-air batteries

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 476-487页

作者： Junkang Chen Yongyue Zhuang Yanxin Qiao Yu Zhang Aihua yuan hu Zhou School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

Exploring efficient and nonprecious metal electrocatalysts of oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)is crucial for developing rechargeable zinc-air batteries(ZABs).herein,an alloying-degree control strategy was employed to fabricate nitrogen-doped carbon sphere(NCS)decorated with dual-phase Co/Co_(7)Fe_(3)heterojunctions(CoFe@NCS).The phase composition of materials has been adjusted by controlling the alloying *** optimal CoFe_(0.08)@NCS electrocatalyst displays a half-wave potential of 0.80 V for ORR and an overpotential of 283 mV at 10 mA·cm^(-2)for OER in an alkaline *** intriguing bifunctional electrocatalytic activity and durability is attributed to the hierarchically porous structure and interfacial electron coupling of highly-active Co_(7)Fe_(3)alloy and metallic Co *** the CoFe_(0.08)@NCS material is used as air-cathode catalyst of rechargeable liquid-state zinc-air battery(ZAB),the device shows a high peak power-density(157 mW·cm^(-2))and maintains a stable voltage gap over 150 h,outperforming those of the benchmark(Pt/C+RuO_(2))-based *** particular,the as-fabricated solid-state flexible ZAB delivers a reliable compatibility under different bending *** work provides a promising strategy to develop metal/alloy-based electrocatalysts for the application in renewable energy conversion technologies.

关键词： bifunctional electrocatalysts oxygen reduction reaction oxygen evolution reaction zinc-air battery metal/alloy carbon sphere

Physical Layer Security Scheme With AoI-Awareness for Industrial IoT Based on Covert Communications

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2025年第1期 276-278页

作者： Yaping Li Zhi-Xin Liu Jia-Wei Su Ya-Zhou yuan the Key Laboratory of Industrial Computer Control Engineering of hebei Province Yanshan University

Dear Editor,Industrial Internet of things(IIoT) is a typical application of cyberphysical system(CPS). In the IIoT, wireless communication is an inevitable trend to replace the deployment-limited wired transmission for cases with large-scale and mobile devices. however, wireless communication gives rise to critical issues related to physical security, such as malicious detections and attacks [1].

关键词：

Fully automatic DOM generation method based on optical flow field dense image matching

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Geo-Spatial Information Science 2023年第2期26卷 242-256页

作者： Wei yuan Xiuxiao yuan yang Cai Ryosuke Shibasaki School of Remote Sensing and Information Engineering Wuhan UniversityWuhanChina Center for Spatial Information Science University of TokyoKashiwaJapan

Automatic Digital Orthophoto Map(DOM)generation plays an important role in many downstream works such as land use and cover detection,urban planning,and disaster *** DOM generation methods can generate promising results but always need ground object filtered DEM generation before otho-rectification;this can consume much time and produce building facade contained *** address this problem,a pixel-by-pixel digital differential rectification-based automatic DOM generation method is proposed in this ***,3D point clouds with texture are generated by dense image matching based on an optical flow field for a stereo pair of images,***,the grayscale of the digital differential rectification image is extracted directly from the point clouds element by element according to the nearest neighbor method for matched ***,the elevation is repaired grid-by-grid using the multi-layer Locally Refined B-spline(LR-B)interpolation method with triangular mesh constraint for the point clouds void area,and the grayscale is obtained by the indirect scheme of digital differential rectification to generate the pixel-by-pixel digital differentially rectified image of a single image ***,a seamline network is automatically searched using a disparity map optimization algorithm,and DOM is smartly *** qualitative and quantitative experimental results on three datasets were produced and evaluated,which confirmed the feasibility of the proposed method,and the DOM accuracy can reach 1 Ground Sample Distance(GSD)*** comparison experiment with the state-of-the-art commercial softwares showed that the proposed method generated DOM has a better visual effect on building boundaries and roof completeness with comparable accuracy and computational efficiency.

关键词： Digital Orthophoto Map(DOM) dense image matching based on optical flow field(OFFDIM) 3D point clouds with texture seamline network accuracy

New characterizations of Musielak-Orlicz-Sobolev spaces via sharp ball averaging functions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Mathematics in China 2019年第1期14卷 177-201页

作者： Sibei yang Dachun yang Wen yuan School of Mathematics and Stat istics Gansu Key Laboratory of Applied Mat hematics and Complex Systems Lanzhou University Lanzhou 730000 China Laboratory of Mathematics and Complex Systems (Ministry of Education of China) School of Mathematical Sciences Beijing Normal University. Beijing 100875 China

We establish a new characterization of the Musielak-Orlicz-Sobolev space on ?n, which includes the classical Orlicz-Sobolev space, the weighted Sobolev space, and the variable exponent Sobolev space as special cases, in terms of sharp ball averaging functions. Even in a special case, namely, the variable exponent Sobolev space, the obtained result in this article improves the corresponding result obtained by P. h?st? and A. M. Ribeiro [Commun. Contemp. Math., 2017, 19: 1650022] via weakening the assumption f ∈ L^1(R^n) into f ∈ L^1loc(R^n), which was conjectured to be true by hosto and Ribeiro in the aforementioned same article.

关键词： Musielak-Orlicz-Sobolev space Orlicz-Sobolev space variable exponent Sobolev space sharp ball averaging function