检索结果-南通市图书馆

Shear strength degradation of gas hydrate-bearing sediment due to partial hydrate dissociation

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2749-2763页

作者： yuan Zhou Jiazuo Zhou {1. Chen Changfu Wei State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China University of Chinese Academy of Sciences Beijing100049China China University of Geosciences Wuhan430074China

Extraction of methane hydrate from subseafloor reservoir may potentially trigger seabed slides and induce *** address the problems,it is crucial to properly characterize the phase equilibrium condition of pore hydrate and the shear strength of the *** one of the key constitutive components,the phase equilibrium condition enforces a constraint over pore gas pressure,temperature and unhydrated water *** a constraint,however,has been traditionally ignored in analyzing the mechanical behavior of hydrate-bearing *** this paper,a series of stepwise hydrate dissociation tests was performed,and the phase equilibrium condition of pore hydrate was determined,providing an effective way to evaluate the unhydrated water content during hydrate ***,a series of direct shear tests was also conducted to explore the shear strength characteristics of the *** is shown that the shear strength of the hydrate-bearing soil can be significantly influenced by pore gas pressure,unhydrated water content,hydrate saturation and several other *** particular,the measured shear strength depends upon the initial water content of the sample,pointing to a potential problem that the shear strength could be wrongly determined if not properly interpreted.A shear strength criterion,which enforces the equilibrium condition of pore hydrate,is developed for hydrate-bearing soil,establishing a link between the equilibrium condition and the shear *** proposed equation describes well the shear strength characteristics of hydrate-bearing soils,remarkably unifying the effects of pore pressure,temperature,water content and hydrate saturation.

关键词： Hydrate-bearing soil Phase equilibrium condition Shear strength Unhydrated water content Mechanical behavior

Experimental and numerical study of hypervelocity impact damage on composite overwrapped pressure vessels

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第1期31卷 58-72页

作者： Yong-pan Duan Run-Qiang Chi Bao-Jun pang yuan Cai Hypervelocity Impact Research Center Harbin Institute of TechnologyHarbin150080China College of Science Heilongjiang University of Science and TechnologyHarbin 150022China

Ground-based tests are important for studying hypervelocity impact(HVI)damage to spacecraft pressure vessels in the orbital debris *** analyzed the damage to composite overwrapped pressure vessels(COPVs)in the HVI tests and classified the damage into non-catastrophic damage and catastrophic *** proposed a numerical simulation method to further study non-catastrophic damage and revealed the characteristics and mechanisms of non-catastrophic damage affected by impact conditions and internal *** fragments of the catastrophically damaged COPVs were collected after the *** crack distribution and propagation process of the catastrophic ruptures of the COPVs were *** findings contribute to understanding the damage characteristics and mechanisms of COPVs by HVIs.

关键词： Orbital debris Hypervelocity impact Composite overwrapped pressure vessels Damage mechanisms

Extraordinary hot extreme in summer 2022 over the Yangtze River basin modulated by the La Nina condition under global warming

在线全文

学校读者我要写书评

暂无评论

Advances in Climate Change Research 2024年第1期15卷 21-30页

作者： Zhen LIAO Yu-Feng yuan Yang CHEN {1.-Mao ZHAI State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China

A widespread and prolonged hot extreme hit the Yangtze River basin in summer 2022,with 300 sites established new temperature records and nearly 96%stations endured more than 40 hot *** the perspective of the combination effect of the global warming and La Nina condition,potential mechanisms of the hot extreme were *** a record-breaking hot extreme was caused by an extremely strong and westward-shifted western Pacific subtropical high(WPSH).The global warming effect contributed primarily to the abnormal hot days in the Yangtze River basin,coupled with the modulation of the La Nina *** sea surface temperature anomaly pattern under La Nina condition favored more convection activities over the western Pacific,encouraging an enhanced and westward-extended *** addition,an observation-based attribution analysis indicates that anthropogenic warming may increase the probability of such extensively persistent hot extremeby1.8 times.

关键词： Hot extreme The Yangtze River basin Global warming Tropical Pacific forcing

Characterization of blueberry exosome-like nanoparticles and miRNAs with potential cross-kingdom human gene targets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第2期13卷 869-878页

作者： Yangfan Leng Liubin Yang Siyi pan Leilei Zhan Fang {1. College of Food Science and Technology Huazhong Agricultural UniversityWuhan 430070China Hubei Key Laboratory of Fruit&Vegetable Processing&Quality Control Huazhong Agricultural UniversityWuhan 430070China Wuhan GeneCreate Biological Engineering Co. Ltd.Wuhan 430070China

Edible plant derived exosome-like nanoparticles(ELNs)have been shown to have multiple nutraceutical ***,the diversity of plant materials makes the plant derived ELN study *** efforts are still needed to explore the feasible isolation methods of edible plant derived ELNs and the possible roles of food-derived ELNs in improving human *** this study,a size exclusion chromatography based method was compared with the traditional ultracentrifugation method to isolate blueberry derived ELNs(B-ELNs),and the miRNA profile of B-ELNs was analyzed by high-throughput sequencing.A total of 36 miRNAs were found to be enriched in B-ELNs compared with berry tissue,and their potential cross-kingdom human gene targets were further *** showed that size exclusion chromatography was effective for B-ELN *** most abundant miRNAs in B-ELNs mainly belonged to the miR1.6 family and miR396 *** gene prediction indicated that B-ELNs could potentially regulate pathways related to the human digestive system,immune system and infectious diseases.

关键词： Edible plant derived exosomes-like nanoparticles Size exclusion chromatography miRNA Target gene prediction Blueberry

Simulation study of the performance of the Very Large Area gamma-ray Space Telescope

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第9期35卷 1-17页

作者： Xu pan Wei Jiang Chuan Yue Shi-Jun Lei Yu-Xin Cui Qiang {1. Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China

The Very Large Area gamma-ray Space Telescope(VLAST)is a mission concept proposed to detect gamma-ray photons through both Compton scattering and electron–positron pair production mechanisms,thus enabling the detection of photons with energies ranging from MeV to *** project aims to conduct a comprehensive survey of the gamma-ray sky from a low-Earth orbit using an anti-coincidence detector,a tracker detector that also serves as a low-energy calorimeter,and a high-energy imaging *** developed a Monte Carlo simulation application of the detector using the GEANT4 toolkit to evaluate the instrument performance,including the effective area,angular resolution,and energy resolution,and explored specific optimizations of the detector *** simulation-based analysis indicates that the current design of the VLAST is physically feasible,with an acceptance above 1. m^(2)sr which is four times larger than that of the Fermi-LAT,an energy resolution better than 2%at 1. GeV,and an angular resolution better than 0.2◦at 1. *** VLAST project promises to make significant contributions to the field of gamma-ray astronomy and enhance our understanding of the cosmos.

关键词： Space astronomy Gamma-ray telescope Calorimeter Monte Carlo simulation

Applications of artificial intelligence to lipid nanoparticle delivery

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第7期90卷 88-97页

作者： Ye yuan Yuqi Wu Jiabei Cheng Kaiyuan Yang Yilin Xia Hongguang Wu Xiaoyong pan Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong UniversityKey Laboratory of System Control and Information ProcessingMinistry of Education of ChinaChina Songjiang Research Institute Songjiang District Central HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

Lipid nanoparticles(LNPs)are nanocarriers composed of four lipid components and can be used for gene therapy,protein replacement,and vaccine ***,LNPs also face several challenges,such as toxicity,immune activation,and low delivery *** overcome these challenges,artificial intelligence can be used to optimize the design and formulation of LNPs,as well as to predict their properties and ***,antibody-targeted conjugation can be used to enhance the specificity and selectivity of LNPs by attaching an antibody that recognizes a specific antigen on the cell surface to LNPs.

关键词： Artificial intelligence Lipid nanoparticles Antibody Targeted conjugation

Risk factors for recurrence of common bile duct stones after surgical treatment and effect of ursodeoxycholic acid intervention

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第1期16卷 103-112页

作者： Wei-Hong yuan Zheng Zhang Qi {1. Bo-Neng Mao Tao yuan Department of Gastroenterology Yixing People’s HospitalYixing 214200Jiangsu ProvinceChina

BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an accurate diagnostic method for choledocholithiasis and treatment option for stone ***,ursodeoxycholic acid(UDCA)can dissolve cholesterol stones and prevent their development and reappearance by lowering the cholesterol concen-tration in *** these treatment options,there are still patients who experience stone *** clinical data of 1.0 patients with choledochal stones who were hospitalized at the Yixing People’s Hospital and underwent ERCP for successful stone extraction between June 2020 and December 2022 were retrospectively *** to the post-ERCP treatment plan,1.0 patients were classified into UDCA(n=47)and control(n=53)*** aimed to assess the clinical efficacy and rate of relapse in the two patient *** then collected information(basic demographic data,clinical characteristics,and serum biochemical indicators)and determined the factors contributing to relapse using logistic regression *** secondary goal was to determine the effects of UDCA on liver function after *** to the control group,the UDCA group demonstrated a higher clinical effectiveness rate of 92.45%vs 78.72%(P1.8.52,32.1.±4.62 vs 45.39±5.69,1.2.32±1..21.vs 1.9.63±1..87,1.2.52±1..25 vs 1.9.36±1..36,1.2.61.1..00 vs 1.1.33±22.09,96.98±1..44 vs 1.1.35±1..57,respectively,all P1..21.)in contrast with the control group(44.68%).Periampullary divertic

关键词： Endoscopic retrograde cholangiopancreatography Recurrence Ursodeoxycholic acid Common bile duct stones Clinical effective rate Risk factors

A Multi-Constraint Path Optimization Scheme Based on Information Fusion in Software Defined Network

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第4期79卷 1399-1418页

作者： Jinlin Xu Wansu pan Longle Cheng Haibo Tan Munan {1. Xiaofeng Li Hefei Institutes of Physical Science Chinese Academy of SciencesHefei230031China University of Science and Technology of China Hefei230026China

The existingmultipath routing in Software Defined Network (SDN) is relatively blind and inefficient, and there is alack of cooperation between the terminal and network sides, making it difficult to achieve dynamic adaptationof service requirements and network resources. To address these issues, we propose a multi-constraint pathoptimization scheme based on information fusion in SDN. The proposed scheme collects network topology andnetwork state information on the network side and computes disjoint paths between end hosts. It uses the FuzzyAnalytic Hierarchy Process (FAHP) to calculate the weight coefficients of multiple constrained parameters andconstructs a composite quality evaluation function for the paths to determine the priority of the disjoint paths. TheSDN controller extracts the service attributes by analyzing the packet header and selects the optimal path for flowrule forwarding. Furthermore, the service attributes are fed back to the path composite quality evaluation function,and the path priority is dynamically adjusted to achieve dynamic adaptation between service requirements andnetwork status. By continuously monitoring and analyzing the service attributes, the scheme can ensure optimalrouting decisions in response to varying network conditions and evolving service demands. The experimentalresults demonstrated that the proposed scheme can effectively improve average throughput and link utilizationwhile meeting the Quality of Service (QoS) requirements of various applications.

关键词： SDN multi-constraint path information fusion FAHP

Complexes of cupric ion and tartaric acid enhanced calcium peroxide Fenton-like reaction for metronidazole degradation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第7期35卷 183-187页

作者： Shiyu pan Bo Cao Deling {1. Tifeng Jiao Qingrui Zhang Shoufeng Tang State Key Laboratory of Metastable Materials Science and Technology Hebei Key Laboratory of Heavy Metal Deep-Remediation in Water and Resource ReuseSchool of Environmental and Chemical EngineeringYanshan UniversityQinhuangdao 066004China

To surmount the obstacles of traditional Fenton method and synchronously utilize Cu^(2+)and polyphenol in water,an improved Fenton-like reaction applying calcium peroxide(CaO_(2))as H_(2)O_(2)source and regulating by the complex of Cu^(2+)-tartaric acid(TA,a representative of polyphenol)was constructed.A typical antibiotic,metronidazole(MTZ)could be effectively eliminated by the Cu^(2+)/TA/CaO_(2)system,and the optimized parameters were as follows:0.1.mmol/L Cu^(2+),2 mmol/L TA,2 mmol/L CaO_(2),and initial *** spectrum confirmed the formation of Cu^(2+)-TA complex,which promoted the Cu^(2+)/Cu+circulation through decreasing the Cu^(2+)/Cu^(+) couple redox potential,which further enhanced the H_(2)O_(2)decomposition and the formation of reactive *** radical was dominant for MTZ degradation,followed by oxygen and superoxide *** degradation intermediates of MTZ were detected and their evolution way was ***,the ternary process showed a wide p H tolerance(3–8)for removing MTZ and broad applicability for eliminating other dyes and *** work provided a reference for Cu-based Fenton-like strategy for organic wastewater settlement.

关键词： Cupric ion Tartaric acid Complexation Calcium peroxide Metronidazole removal