检索结果-南通市图书馆

Degradation of extracellular genomic, plasmid DNA and specific antibiotic resistance genes by chlorination

Frontiers of Environmental Science & Engineering 2019年第3期13卷 115-126页

作者： Menglu Zhang Sheng Chen xin yu Peter Vikesland Amy Pruden Key Laboratory of Urban Environment and Health Institute of Urban Environment Chinese Academy of Sciences Xiamen 361021 China University of Chinese Academy of Science Beijing 100049 China Department of Civil and Environmental Engineering Virginia Tech Blacksburg VA 24060 USA

There is a need to improve understanding of the effect of chlorine disinfection on antibiotic resistance genes (ARGs) in order to advance relevant drinking water, wastewater, and reuse treatments. However, few studies have explicitly assessed the physical effects on the DNA. Here we examined the effects of free chlorine (1-20 mg CI2/L) on extracellular genomic, plasmid DNA and select ARGs. Chlorination was found to decrease the fluorometric signal of extracellular genomic and plasmid DNA (ranging from 0.005 to 0.05 μg/mL) by 70%, relative to a no-chlorine control. Resulting DNA was further subject to a fragment analysis using a Bioanalyzer, indicating that chlorination resulted in fragmentation. Moreover, chlorine also effectively deactivated both chromosomal- and plasmidborne ARGs, mecK and tetA., respectively. For concentrations >2 mg CI2//L× 30 min, chlorine efficiently reduced the qPCR signal when the initial concentration of ARGs was 10^5 copies/μL or less. Notably, genomic DNA and mecA gene signals were more readily reduced by chlorine than the plasmid-bome tetK gene (by ~2 fold). Based on the results of qPCR with short (~200 bps) and long amplicons (-1200 bps), chlorination could destroy the integrity of ARGs, which likely reduces the possibility of natural transformation. Overall, our findings strongly illustrate that chlorination could be an effective method for inactivating extracellular chromosomal- and plasmid-bome DNA and ARGs.

关键词： Antibiotic resistance Antibiotic resistance genes (ARGs) Extracellular DNA/ARGs Chlorination

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Review on design and evaluation of environmental photocatalysts

引用

Frontiers of Environmental Science & Engineering 2018年第5期12卷 9-40页

作者： xin Li Jun Xie Chuanjia Jiang Jiaguo yu Pengyi Zhang College of Forestry and Landscape Architecture Key Laboratory of Energy Plants Resource and UtilizationMinistry of AgricultureKey Laboratory of Biomass Energy of Guangdong Regular Higher Education InstitutionsSouth China Agricultural UniversityGuangzhou 510642China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China School of Environment State Key Joint Laboratory of Environment Simulation&Pollution ControlTsinghua UniversityBeijing 100084China

Heterogeneous photocatalysis has long been considered to be one of the most promising approaches to tackling the myriad environmental ***,there are still many challenges for designing efficient and cost-effective photocatalysts and photocatalytic degradation systems for application in practical environmental *** this review,we first systematically introduced the fundamental principles on the photocatalytic pollutant ***,the important considerations in the design of photocatalytic degradation systems are carefully addressed,including charge carrier dynamics,catalytic selectivity,photocatalyst stability,pollutant adsorption and photodegradation ***,the underlying mechanisms are thoroughly reviewed,including investigation of oxygen reduction properties and identification of reactive oxygen species and key *** review in environmental photocatalysis may inspire exciting new directions and methods for designing,fabricating and evaluating photocatalytic degradation systems for better environmental remediation and possibly other relevant fields,such as photocatalytic disinfection,water oxidation,and selective organic transformations.

关键词： Photocatalytic degradation Environmental remediation Charge carrier dynamics Reactive oxygen species O_(2)reduction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

PAM Templating Mechanism for Synthesis of A Novel LiFePO_4 Cathode Material

引用

Chemical Research in Chinese Universities 2005年第3期21卷 309-314页

作者： YANGShu-ting ZHAONa-hong DONGHong-yu yuEHong-yun YANGJin-xin CollegeofChemistryandEnvironmentalScience HenanNormalUniversityXinxiang453007P.R.China HenanNewPowerMaterialResearchCenter Xinxiang453007P.R.China

A novel templated LiFePO_4 cathode material was prepared with linear polyacrylamide, which exhibited excellent electrochemical properties, such as a 109.3 mA·h/g capacity at a rate of C/3 and a 120 mA·h/g capacity at a rate of C/6 as well as a good cycliability. We proposed the templating mechanism based upon the precursors′ TG-DTA curves, X-ray diffraction patterns and FTIR spectra of the samples at different temperatures. A tapping-mode atomic force microscope was used to investigate the surfaces of the end products. We found that the polyacrylamide template produced metal organic compounds in the cross-linked gel precursor, and thereby modified the crystallization and particle surfaces during calcining. The template was “removed” in the end, which was partially pyrolyzed into the spiral carbon to form a conductive network with nanocrys\|talline LiFePO_4 highly monodispersed in it.

关键词： LiFePO_4 Lithium ion battery Template Mechanism Tapping-mode atomic force microscope

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pure phase MoN: preparation by chemical-diffused permeation and enhanced conductivity with rare earth Gd

引用

Rare Metals 2015年第2期34卷 137-142页

作者： xin Li Chao Gao yu-Zhi Jiang Xi-Kun Li School of Materials Science and Engineering Shenyang Ligong University

MoN was prepared by rare earth Gd thermaldiffused permeation method via solid–gas interface reaction using（NH_4）_4[NiMo6O_24H_6]·7H_2O（abbreviated as NiMo6） as the precursor. Thermo-gravimetric differential thermal analysis（TG–DTA） was used to study the product＇s stability. The results of X-ray diffractometer（XRD）and X-ray photoelectron spectroscopy（XPS） indicate that a new hexagonal crystal MoN forms after the rare earth gas permeation and Gd3＋are diffused as substitution ions into the crystal lattice of MoN, and the surface valence of elemental content was measured by XPS. The conductivity results by direct current（DC） four-probe method show that MoN obtained from the Gd thermal permeation exhibits conductor character in the temperature range of 298–740 K and semiconductor behavior in 740–800 K.

关键词： Rare earth permeation MoN Conductivity Gd

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

缺血性脑血管病患者介入术后认知功能障碍风险的列线图预测模型构建

引用

医药论坛杂志 2024年第5期45卷 497-501页

作者：杨钰张欢李新月黄钟晓李亚茹王聪温昌明南阳市中心医院神经内科河南南阳473000

目的分析缺血性脑血管病患者介入术后认知功能障碍发生的危险因素,并构建列线图预测模型,为临床早期预测及管理提供参考。方法选取2020年3月至2022年5月于南阳市中心医院接受介入术治疗的125例缺血性脑血管病患者为研究对象,依据术后6... 详细信息

目的分析缺血性脑血管病患者介入术后认知功能障碍发生的危险因素,并构建列线图预测模型,为临床早期预测及管理提供参考。方法选取2020年3月至2022年5月于南阳市中心医院接受介入术治疗的125例缺血性脑血管病患者为研究对象,依据术后6个月是否发生认知功能障碍分为发生组70例、未发生组55例。采用logistic回归模型分析介入术后认知功能障碍发生的影响因素,并绘制列线图预测模型。采用区分度(Discrimination)、校准度(Calibration)、Hosmer-Lemeshow拟合优度检验对列线图预测模型进行验证。结果125例缺血性脑血管病患者介入术后认知功能障碍发生率为56.00%;伴有高血压、糖尿病、冠心病、高脂血症、颈动脉狭窄、无体育锻炼、淀粉样蛋白β-42(Aβ42)≤16.46 pg/mL、颈动脉内膜中层厚度(CIMT)>1.11 mm、Tau蛋白>18.12 pg/mL是介入术后认知功能障碍发生的危险因素(P<0.05);列线图预测模型预测认知功能障碍发生的一致性指数(C-index)、Discrimination、Calibration分别为0.934、0.718、0.822;Hosmer-Lemeshow拟合优度检验=0.635,P=0.422。结论高血压、糖尿病、体育锻炼、冠心病、高脂血症、颈动脉狭窄、CIMT、Aβ42、Tau蛋白是缺血性脑血管病患者介入术后认知功能障碍的影响因素,基于上述影响因素构建列线图预测模型,该模型具有一定预测价值,可作为临床医师预判介入术后认知功能障碍发生的辅助工具,指导临床早期干预。

关键词：缺血性脑血管病认知功能障碍列线图预测模型影响因素

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

纵膈异常肿瘤患者PICC置管方法研究

引用

医院管理论坛 2024年第1期41卷 48-50,63页

作者：周萍俞新燕吴怡高利琴王慧勤胡胜男应丽浙江省肿瘤医院中国科学院杭州医学研究所

总结43例纵膈异常肿瘤患者行经外周静脉置入中心静脉导管(peripherally inserted central catheter,PICC)的实践经验。针对纵膈异常肿瘤患者PICC置管过程中易出现导管置入长度测量不准确以及送管困难等问题,通过多学科团队合作,构建科... 详细信息

总结43例纵膈异常肿瘤患者行经外周静脉置入中心静脉导管(peripherally inserted central catheter,PICC)的实践经验。针对纵膈异常肿瘤患者PICC置管过程中易出现导管置入长度测量不准确以及送管困难等问题,通过多学科团队合作,构建科学的临床操作方案:置管前增加胸部增强CT评估,胸部CT结合体表测量确定导管预置入长度,置管中注意送管技巧及运用心电定位技术减少送管困难,及时发现导管异位,置管后特殊案例资料填写并加强延续性管理。43位患者成功留置PICC导管,将导管置入理想位置为34例,置入理想位置准确率为79.1%,上腔静脉下段位置7例,右心房2例,2例患者经导管外拔处理后导管尖端位于理想位置。

关键词：纵膈异常经外周静脉置入中心静脉导管置管策略

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study on hydrodynamic vibration in fluidic flowmeter

引用

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第9期8卷 1422-1428页

作者： WANG Chi-yu ZOU Jun FU xin YANG Hua-yong Institute State Key Laboratory of Fluid Power Transmission amt Control Zhejiang University Hangzhou 310027 China

The characteristics of the fluidic flowmeter,which is a combination of impinged concave wall and bistable fluid amplifier,is investigated by experimental studies and numerical simulations. The numerical approaches are utilized to examine the time dependent flow field and pressure field inside the proposed flowmeter. The effect of varying structural parameters on flow characteristics of the proposed fluidic flowmeter is investigated by computational simulations for the optimization. Both the simulation and experimental results disclose that the hydrodynamic vibration,with the same intensity,frequency and 180° phase shift,occurs at axisymmetric points in the feedback channel of the fluidic flowmeter. Using the structural combination of impinged concave wall and bistable fluid amplifier and differential signal processing technique,a novel fluidic flowmeter with excellent immunity and improved sensibility is developed.

关键词：液体流量计水力振动柯恩达效应流量测量

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

供给侧改革视域下医学院校“I-SPARK”本科药学人才培养体系的构建

引用

药学教育 2024年第3期40卷 1-5页

作者：于海琳许贯虹李歆姚东宁韩峰季勇沈瑞林南京医科大学药学院南京211166 南京医科大学医学人文研究院南京211166

在供给侧改革视域下,南京医科大学聚焦新时期“懂医精药”本科药学人才培养的要求,基于以学生为主体(I)这个中心,从科研促进教学(Scientific Research Promoting Teaching)、以患者为中心(Patient-centered Humanistic Quality Cultivat... 详细信息

在供给侧改革视域下,南京医科大学聚焦新时期“懂医精药”本科药学人才培养的要求,基于以学生为主体(I)这个中心,从科研促进教学(Scientific Research Promoting Teaching)、以患者为中心(Patient-centered Humanistic Quality Cultivation)、产教协同育人(Assurance System of Cooperation Education)、创新实训实践(Research and Training Bases)、药苑育人生态(Keen Sense of Patriotism and Responsibility)五方面探索并实践医学院校“I-SPARK”本科药学人才培养体系改革,取得了较好的实践效果。

关键词：供给侧改革医学院校本科药学人才培养 “I-SPARK”

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Kondo scattering in underdoped Nd1-xSrxNiO2 infinite-layer superconducting thin films

引用

National Science Review 2023年第11期10卷 96-102页

作者： Ting-Na Shao Zi-Tao Zhang yu-Jie Qiao Qiang Zhao Hai-Wen Liu xin-Xiang Chen Wei-Min Jiang Chun-Li Yao xing-yu Chen Mei-Hui Chen Rui-Fen Dou Chang-Min Xiong Guang-Ming Zhang Yi-Feng Yang Jia-Cai Nie Department of Physics Beijing Normal University State Key Laboratory of Low-Dimensional Quantum Physics and Department of Physics Tsinghua University Frontier Science Center for Quantum Information Beijing National Laboratory for Condensed Matter Physics and Institute of Physics Chinese Academy of Sciences School of Physical Sciences University of Chinese Academy of Sciences Songshan Lake Materials Laboratory

The recent discovery of superconductivity in infinite-layer nickelates generates tremendous research endeavors, but the ground state of their parent compounds is still under debate. Here, we report experimental evidence for the dominant role of Kondo scattering in the underdoped Nd1-xSrxNiO2thin films. A resistivity minimum associated with logarithmic temperature dependence in both longitudinal and Hall resistivities are observed in the underdoped Nd1-xSrxNiO2samples before the superconducting transition. At lower temperatures down to 0.04 K, the resistivities become saturated, following the prediction of the Kondo model. A linear scaling behavior σx yAHE～ σx xbetween anomalous Hall conductivity σx yAHEand conductivity σx x is revealed, verifying the dominant Kondo scattering at low temperature. The effect of weak(anti-)localization is found to be secondary. Our experiments can help in clarifying the basic physics in the underdoped Nd1-xSrxNiO2infinite-layer thin films.

关键词： Kondo scattering superconductivity underdoped infinite-layer nickelate thin film

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Pose optimization based on integral of the distance between line segments

引用

Science China Technological Sciences 2016年第1期59卷 135-148页

作者： ZHANG yueQiang LI xin LIU HaiBo SHANG Yang yu QiFeng College of Aerospace Science and Engineering National University of Defense Technology Hunan Provincial Key Laboratory of Image Measurement and Vision Navigation

In this paper, new solutions for the problem of pose estimation from correspondences between 3D model lines and 2D image lines are proposed. Traditional line-based pose estimation methods rely on the assumption that the noises(perpendicular to the line) for the two endpoints are statistically independent. However, these two noises are in fact negatively correlated when the image line segment is fitted using the least-squares technique. Therefore, we design a new error function expressed by the average integral of the distance between line segments. Three least-squares techniques that optimize both the rotation and translation simultaneously are proposed in which the new error function is exploited. In addition, Lie group formalism is utilized to describe the pose parameters, and then, the optimization problem can be solved by means of a simple iterative least squares method. To enhance the robustness to outliers existing in the match data, an M-estimation method is developed to convert the pose optimization problem into an iterative reweighted least squares problem. The proposed methods are validated through experiments using both synthetic and real-world data. The experimental results show that the proposed methods yield a clearly higher precision than the traditional methods.

关键词： machine vision perspective-n-line problem line distance function pose optimization M-estimation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：