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Association between COX-2-1195G>A polymorphism and gastrointestinal cancer risk: A meta-analysis

World Journal of Gastroenterology 2017年第12期23卷 2234-2245页

作者： Xiao-Wei Zhang Jun Li yu-xing jiang yu-Xiang Chen Department of Gastrointestinal and Vascular Surgery Deyang People's Hospital Department of General Surgery and Center for Minimal Invasive Gastrointestinal Surgery Southwest Hospital Third Military Medical University

AIM To perform a meta-analysis to investigate the association between cyclooxygenase-2(COX-2)-1195G>A gene polymorphism and gastrointestinal cancers. METHODS Publications related to the COX-2-1195G>A gene polymorphism and gastrointestinal cancers published before July 2016 were retrieved from Pub Med, EMBASE, Web of Science, China Biological Medicine Database, China National Knowledge Infrastructure, and CQVIP Database. Meta-analysis was performed using Stata11.0 software. The strength of the association was evaluated by calculating the combined odds ratios(ORs) and the corresponding 95%CIs. The retrieved publications were excluded or included one by one for sensitivity analysis. In addition, the funnel plot, Begg's rank correlation test, and Egger's linear regression method were applied to analyse whether the included publications had publication bias. RESULTS A total of 24 publications related to the COX-2-1195G>A gene polymorphism were included, including 28 studies involving 11043 cases and 18008 controls. The meta-analysis results showed that the COX-2-1195G>A gene polymorphism significantly correlated with an increased risk of gastrointestinal cancers, particularly gastric cancer(A vs G: OR = 1.35; AA/AG vs GG: OR = 1.54; AA vs GG/AG: OR = 1.43; AA vs GG: OR = 1.80; AG vs GG: OR = 1.35). Compared to the Caucasian population in America and Europe, the COX-2-1195G>A gene polymorphism in the Asian population(A vs G: OR = 1.30; AA/AG vs GG: OR= 1.50; AA vs GG/AG: OR = 1.35; AA vs GG: OR = 1.71; AG vs GG: OR = 1.37) significantly increased gastrointestinal cancer risk. The sensitivity analysis(P A gene polymorphism might be a potential risk factor for gastrointestinal cancers. Further validation by a large homogeneous study is warranted.

关键词： COX-2 -1195G>A Polymorphism Meta-analysis Gastrointestinal cancer

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Synthesis of novel thiol-functionalized mesoporous silica nanorods and their sorbent properties on heavy metals

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Frontiers of Materials Science 2012年第3期6卷 278-282页

作者： Xi CHEN Qiang CAI Lin-Hao SUN Wei ZHANG xing-yu jiang Department of Materials Science and Engineering Tsinghua UniversityBeijing 100084China National Center for Nanoscience and Technology Beijing 100190China

Novel thiol-functionalized mesoporous silica nanorods （MSNRs） were synthesized through a base co-condensation method, in which two organoalkoxysilanes, tetraethoxylsilane （TEOS） and bis[3-（triethoxysilyl）propyl]tetrasulfide （TESPT）, were used as silica precursors simultaneously. TESPT was firstly used for both morphology control and inner surface functionalization of mesoporous silica hybrid materials. The micro- structures as well as porous character of the MSNRs were characterized by means of SEM, XRD, TEM and N2 sorption measurements. Infrared spectrum analysis and heavy metal ions （Ag＋ and Cd2＋） adsorption measurements were carried out to confirm the functionalized framework of MSNRs.

关键词： nanocomposite porous material morphology control inner surfacefunctionalization sorbent

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Surface decoration of mesocarbon microbeads with multifunctional TiNbO_(4-x)@C coating layer as high rate and stable anode of Li-ion batteries

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Rare Metals 2024年第5期43卷 2053-2066页

作者： Jia-Mei Lai Zhi-Min Zou yu Bai yu-Tao xing Chun-Hai jiang Fujian Provincial Key Laboratory of Functional Materials and Applications Institute of Advanced Energy MaterialsSchool of Materials Science and EngineeringXiamen University of TechnologyXiamen 361024China Shanghai XFH Science and Technology Development Co. Ltd.Shanghai 200949China Fujian XFH New Energy Materials Co. Ltd.Yong'an 366000China Shenzhen XFH Science and Technology Co. Ltd.Shenzhen 518071China Laboratorio de Microscopia Eletronica de Alta Resolucao Centro de Caracterizagao Avangada Para a Industria de Petroleo(LaMAR/CAIPE)Universidade Federal FluminenseNiteroiRJ 24210-346Brazil

Surface modification of graphite anode with electroactive matters has been proven of a more practical strategy in enhancing the performance of Li-ion batteries than exploring alternative novel anode ***,rutile TiNbO_(4-x) nanoparticles with a tunnel structure are employed as multifunctional decoration substances in combination with a carbon coating layer to improve the rate and cycle properties of mesocarbon microbeads(MCMBs).As compared to pristine MCMB,the Li^(+)diffusion coefficients of the composite anodes are enhanced due to the synergistic effect of TiNbO_(4-x)@***,the overcharge and voltage polarization of the composite anodes at high rate are obviously minimized due to the current sharing effect of the high-potential TiNbO_(4-x).Moreover,the amorphous Li_(y)TiNbO_(4-x) converted from TiNbO_(4-x) in the initial lithiation process can deliver pseudocapacitive capacity to the composite anodes from the second *** of these functions of TiNbO_(4-x)@Ccoating layer have directly contributed to the improved rate and cycle performance of the MCMB/TiNbO_(4-x)@C composite *** one containing 12.0 wt%TiNbO_(4-x) exhibits a high reversible specific capacity of 118 m Ah·g^(-1)at 10C(1C=372 m A·g^(-1)),together with a high capacity retention of 90.9%after 300 cycles at 3C,which are all much superior to those of pristine MCMB.

关键词： Li-ion batteries MCMB TiNbO_(4-x)@C Surface decoration Rate capability

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Progress of nanoscience in China

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Frontiers of physics 2014年第3期9卷 257-288页

作者： yu-Liang Zhao Yan-Lin Song Wei-Guo Song Wei Liang xing-yu jiang Zhi-Yong Tang Hong-xing Xu Zhi-Xiang Wei yun-Qi Liu Ming-Hua Liu Lei jiang Xin-He Bao Li-Jun Wan Chun-Li Bai National Center for Nanoscience and Nanotechnology Beijing 100190 China Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China Institute of Physics Chinese Academy of Sciences Beijing 100190 China Institute of High Energy Physics Chinese Academy of Sciences Beijing 100039 China Institute of Biophysics Chinese Academy of Sciences Beijing 100190 China School of Chemistry and Environment Beijing University of Aeronautics and Astronautics Beijing 100191 China Shenyang Branch Chinese Academy of Seienees Shenyang 110004 China Chinese Academy of Sciences Beijing 100864 China

Fast evolving nanoseienees and nanotechnology in China has made it one of the front countries of nanotechnology development. Ill this review, we summarize some most recent progresses in nanoseienee research and nanotechnology development in China. The topics we selected in this article include llano-fabrication, nanocatalysis, bioinspired nanoteehnology, green printing nanotechnology, nanoplasmonics, nanomedicine, nanomaterials and their applications, energy and environmental nanoteehnology, nano EHS （nanosafety）, etc. Most of them have great potentials in applications or application-related key issues in future.

关键词： nanoscience nanotechnology nanomaterials nanomedicine plasmonics fal)rication catalysis nano EHS (nanosafety)

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Adverse Effects of Opioid Analgesics in Osteoarthritis Treatment:A Global Meta-Analysis,2000-2022

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China CDC weekly 2024年第25期6卷 589-596,I0001-I0012页

作者： Heng jiang xing xing He Zhu Tuo Dong School of Public Health Harbin Medical UniversityHarbin CityHeilongjiang ProvinceChina School of Public Health Peking UniversityBeijingChina

Osteoarthritis(OA)treatment commonly depends on nonsteroidal anti-inflammatory drugs and opioid ***,the clinical use of opioids is controversial due to their adverse effects and addiction *** study,drawing on 24 randomized controlled trials(RCTs)with a total of 9,586 patients,thoroughly explored the various side effects associated with opioid use in OA *** results provide additional insight into the non-addictive risks of opioids and may assist clinicians in their judicious use,potentially fostering the advancement of safer treatment *** reducing the risks of misuse and addiction,public health and safety can be enhanced.

关键词： potential thoroughly insight

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A Novel Foreign Object Detection Method in Transmission Lines Based on Improved YOLOv8n

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Computers, Materials & Continua 2024年第4期79卷 1263-1279页

作者： Yakui Liu xing jiang Ruikang Xu Yihao Cui Chenhui yu Jingqi Yang Jishuai Zhou School of Mechanical and Automotive Engineering Qingdao University of TechnologyQingdao266520China State Key Laboratory of Electrical Insulation and Power Equipment Xi’an Jiaotong UniversityXi’an710049China Key Lab of Industrial Fluid Energy Conservation and Pollution Control Qingdao University of TechnologyMinistry of EducationQingdao266520China

The rapid pace of urban development has resulted in the widespread presence of construction equipment andincreasingly complex conditions in transmission corridors. These conditions pose a serious threat to the safeoperation of the power *** vision technology, particularly object recognition technology, has beenwidelyemployed to identify foreign objects in transmission line images. Despite its wide application, the technique faceslimitations due to the complex environmental background and other auxiliary factors. To address these challenges,this study introduces an improved YOLOv8n. The traditional stepwise convolution and pooling layers are replacedwith a spatial-depth convolution (SPD-Conv) module, aiming to improve the algorithm’s efficacy in recognizinglow-resolution and small-size objects. The algorithm’s feature extraction network is improved by using a LargeSelective Kernel (LSK) attention mechanism, which enhances the ability to extract relevant features. Additionally,the SIoU Loss function is used instead of the Complete Intersection over Union (CIoU) Loss to facilitate fasterconvergence of the algorithm. Through experimental verification, the improved YOLOv8n model achieves adetection accuracy of 88.8% on the test set. The recognition accuracy of cranes is improved by 2.9%, which isa significant enhancement compared to the unimproved algorithm. This improvement effectively enhances theaccuracy of recognizing foreign objects on transmission lines and proves the effectiveness of the new algorithm.

关键词： YOLOv8n data enhancement attention mechanism SPD-Conv Smoothed Intersection over Union(SIoU)Loss

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Polyoxometalate as the assembly material to self-assembled Ni(OH)_(2) nanosheets with electrocatalytic performance

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Nano Research 2024年第8期17卷 7061-7067页

作者： Danyang He Tianyang Li Luozhen jiang Fei Wang Zihao xing Nan Wang Zhiyu Jia Guo-yu Yang Key Laboratory of Cluster Science Ministry of EducationSchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing 100081China Shanghai Advanced Research Institute Chinese Academy of ScienceShanghai 201210China Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education Facluty of ChemistryNortheast Normal UniversityChangchun 130024China

Developing non-noble metal-based electrocatalyst with high catalytic activity is essential for advancing hydrogen energy *** study introduces a hydrothermal method for synthesizing order Ni(OH)_(2) nanosheets,with H_(3)O_(40)PW_(12)(denoted as PW_(12))loaded onto reduced graphene oxide(rGO)coated on nickel foam(referred to as PW_(12)-Ni(OH)_(2)/rGO).This method contrasts with the electrodeposition of Ni(OH)_(2),where PW_(12) is added to the synthetic system to direct the assembly and morphology of the Ni(OH)_(2) through a hydrothermal *** this work,the nickel foam acts dual roles as both the substrate and the source of nickel for the formation of Ni(OH)_(2).The PW_(12)-Ni(OH)_(2)/rGO nanosheets,when successfully prepared and loaded onto the nickel foam(NF),exhibited superior electrocatalytic activity for the hydrogen evolution reaction(HER)in an alkaline electrolyte,achieving a current density of 10 mA·cm^(-2) at an overpotential of 69 ***,we endeavored to expand the application of this material towards the oxygen evolution reaction(OER)by preparing PW_(12)-(Fe/Co)Ni(OH)_(2)/rGO through the addition of metal *** nanocomposite displayed outstanding electrocatalytic activity in alkaline electrolytes,with a current density of 10 mA·cm^(-2)at an overpotential of 211 mV,and demonstrated excellent stability over a 50 h period in a 1 M KOH *** results presented in this paper offer an effective strategy for the preparation of polyoxometalate-based inorganic materials with diverse functionalities,applicable to both HER and OER.

关键词： polyoxometalate Ni(OH)_(2) assembly hydrogen evolution reaction oxygen evolution reaction

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Are Solar Active Regions Born with Neutralized Currents?

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Research in Astronomy and Astrophysics 2024年第7期24卷 79-88页

作者： Aiying Duan Yaoyu xing Chaowei jiang Planetary Environmental and Astrobiological Research Laboratory(PEARL) School of Atmospheric SciencesSun Yat-sen UniversityZhuhai 519000China yunnan Key Laboratory of the Solar Physics and Space Science Kunming 650216China Key Laboratory of Tropical Atmosphere-Ocean System Sun Yat-sen UniversityMinistry of EducationZhuhai 519000China Institute of Space Science and Applied Technology Harbin Institute of TechnologyShenzhen 518055China

Solar active regions(ARs)are formed by the emergence of current-carrying magnetic flux tubes from below the *** for an isolated flux tube the direct and return currents flowing along the tube should balance with each other,it remains controversial whether such a neutralization of currents is also maintained during the emergence *** we present a systematic survey of the degrees of the current neutralization in a large sample of flux-emerging ARs which appeared on the solar disk around the central meridian from 2010 to *** vector magnetograms taken by Helioseismic and Magnetic Imager onboard Solar Dynamic Observatory are employed to calculate the distributions of the vertical current density at the *** on the main phase of flux emergence,i.e.,the phase in which the total unsigned magnetic flux is continuously increased,we statistically examined the ratios of direct to return currents in all the *** a large-sample statistical study suggests that most of the ARs were born with currents close to *** degree of current neutralization seems to be not affected by the active-region size,the active-region growing rate,and the total unsigned *** only correlation of significance as found is that the stronger the magnetic field nonpotentiality is,the further the AR deviates from current neutrality,which supports previous event studies that eruption-productive ARs often have non-neutralized currents.

关键词： Sun magnetic fields-Sun flares-Sun corona-Sun coronal mass ejections(CMEs)

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Comparative analysis of DNA-SIP and magnetic-nanoparticle mediated isolation (MMI) on unraveling dimethoate degraders

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Frontiers of Environmental Science & Engineering 2024年第1期18卷 59-69页

作者： Luning Lian Yi xing Dayi Zhang Longfei jiang Mengke Song Bo jiang School of Energy and Environmental Engineering University of Science&Technology BeijingBeijing 100083China Beijing Key Laboratory of Resource-oriented Treatment of Industrial Pollutants University of Science&Technology BeijingBeijing 100083China National Environmental and Energy Science and Technology International Cooperation Base University of Science&Technology BeijingBeijing 100083China College of New Energy and Environment Jilin UniversityChangchun 130021China Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China College of Natural Resources and Environment South China Agricultural UniversityGuangzhou 510642China National Engineering Laboratory for Site Remediation Technologies Beijing 100015China

Microorganisms are crucial in the bioremediation of organophosphorus pesticides. However, most functional microorganisms (> 99%) are yet to be cultivated. This study applied two cultivation-independent approaches, DNA-SIP and magnetic-nanoparticle mediated isolation (MMI), to identify the functional microorganisms in degrading dimethoate in agricultural soils. MMI identified five dimethoate degraders: Pseudomonas, Bacillus, Ramlibacter, Arthrobacter, and Rhodococcus, whereas DNA-SIP identified three dimethoate degraders: Ramlibacter, Arthrobacter, and Rhodococcus. Also, MMI showed higher resolution than DNA-SIP in identifying functional microorganisms. Two organic phosphohydrolase (OPH) genes: ophC2 and ophB, were involved in dimethoate metabolism, as revealed by DNA-SIP and MMI. The degradation products of dimethoate include omethoate, O,O,S-trimethyl thiophosphorothioate, N-methyl-2-sulfanylacetamide, O,O-diethyl S-hydrogen phosphorodithioate, O,O,O-trimethyl thiophosphate, O,O,S-trimethyl thiophosphorodithioate, and O,O,O-trimethyl phosphoric. This study emphasizes the feasibility of using SIP and MMI to explore the functional dimethoate degraders, expanding our knowledge of microbial resources with cultivation-independent approaches.

关键词： Stable isotope probing(SIP) Magnetic-nanoparticle mediated isolation(MMI) Dimethoate Biodegradation Cultivation-independent approach

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Efficient recovery of tungsten from scheelite concentrates using a sulfur-phosphorus mixed acid leaching system

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Tungsten 2024年第4期6卷 821-832页

作者： jiang-Tao Li Li-Li Gao Zhong-Wei Zhao Xu-Heng Liu xing-yu Chen School of Metallurgy and Environment Central South University Key Laboratory of Hunan Province for Metallurgy and Material Processing of Rare Metals

In recent years,a new process for leaching scheelite concentrates with sulfur-phosphorus mixed acid has been successfully *** process suffers from the elimination of the retarding effect of calcium sulfate,the selective extraction of tungsten from the H3PW12O40-H2SO4-H3PO4mixture solution,and the removal of introduced ***,in this paper,we investigated the inhibition measures of a calcium sulfate-blocking membrane,the selective extraction of tungsten by ion exchange,and the removal of phosphorus by the magnesium ammonium salt *** results showed that the addition of calcium sulfate whisker seeds and a higher H3PO4concentration inhibited spontaneous diffuse nucleation,promoted crystal growth,and avoided the formation of a dense blocking *** 98 wt.% of the scheelite concentrate was digested by *** selective adsorption of PW12O403-was realized using D301 resin,and the extraction efficiency of tungsten exceeded 99.9%.After desorption with ammonia water,PW12O403-was depolymerized into WO42-and PO43-.99.9 wt.% of phosphorus was removed in the form of MgNH4PO4by the magnesium ammonium salt method,and the residual phosphorus concentration in the solution was lower than 10 mg·*** purification,the highest-grade ammonium paratungstate product was prepared by evaporative crystallization.

关键词： Calcium sulfate Ion exchange Scheelite concentrates Sulfur-phosphorus mixed acid Tungsten

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