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糖皮质激素治疗老年新型冠状病毒感染后反复发热的病例分析

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中国临床药理学杂志 2024年第1期40卷 121-125页

作者：邓美玉于旭红张令晖陈玲中国人民解放军第三〇五医院呼吸内科北京100017 中国人民解放军第三〇五医院药局北京100017

目的探讨老年新型冠状病毒感染后反复发热的临床特点和治疗方法。方法收集4例老年新型冠状病毒感染后反复发热的病例资料,分析其临床特点和糖皮质激素治疗的疗效。结果患者男3例,女1例,年龄82~86岁,发热时间24~37 d,其中3例肺部病变轻,... 详细信息

目的探讨老年新型冠状病毒感染后反复发热的临床特点和治疗方法。方法收集4例老年新型冠状病毒感染后反复发热的病例资料,分析其临床特点和糖皮质激素治疗的疗效。结果患者男3例,女1例,年龄82~86岁,发热时间24~37 d,其中3例肺部病变轻,1例肺部病变重。在4例患者中,2例用小剂量糖皮质激素(甲泼尼龙片初始剂量20 mg·d^(-1)),2例初始剂量较大(甲泼尼龙40 mg·d^(-1)),退热时间2~4 d。肺部病变轻的3例患者应用激素疗程短,为3~6周;肺部病变重的1例应用激素疗程长,为23周。结论对老年新型冠状病毒感染后反复发热的病例,如肺部病变轻微,可试用小剂量糖皮质激素短疗程治疗;如肺部病变重,可适当增大剂量,延长疗程。

关键词：糖皮质激素治疗新型冠状病毒感染反复发热老年患者

Robust Valuation,Arbitrage Ambiguity and Profit&Loss Analysis

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Journal of the Operations Research Society of China 2018年第1期6卷 59-83页

作者： yu-hong xu Mathematical Center for Interdiscipline Research and School of Mathematical Sciences Soochow UniversitySuzhou 215006China

Model uncertainty is a type of inevitable financial *** on the choice of pricing model may cause great financial *** this paper we investigate financial markets with mean-volatility *** for stock market and option market with uncertain prior distributions are established by Peng’s G-stochastic *** the hedging market,the upper price of an(exotic)option is derived following the Black–Scholes–Barenblatt *** is interesting that the corresponding Barenblatt equation does not depend on mean uncertainty of the underlying *** definitions of arbitrage for super-and sub-hedging strategies are presented such that the super-and sub-hedging prices are *** particular,the condition of arbitrage for sub-hedging strategy fills the gap of the theory of arbitrage under model *** we show that the term K of finite variance arising in the superhedging strategy is interpreted as the max Profit&Loss(P&L)of shorting a delta-hedged *** ask-bid spread is in fact an accumulation of the superhedging P&L and the sub-hedging P&L.

关键词： Arbitrage Risk-neutral valuation Profit&Loss Overestimation G-expectation

铝板水热碳吸附工艺制备APC/Al层状复合材料的显微组织、力学性能和摩擦学性能

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Transactions of Nonferrous Metals Society of China 2024年第1期34卷 108-121页

作者：陈奕涵许红雨姜博王晔胡茂良吉泽升哈尔滨理工大学材料科学与化学工程学院哈尔滨150080 哈尔滨理工大学先进制造智能化技术教育部重点实验室哈尔滨150080

采用铝板水热碳吸附工艺(HTCAP)和真空热压烧结工艺(VHPS)制备无定形碳(APC)/Al层状复合材料,研究葡萄糖溶液浓度对其显微组织、力学性能和摩擦学性能的影响。结果表明,APC在层间分布均匀,并且通过Al的扩散与基体形成良好的界面结合。... 详细信息

采用铝板水热碳吸附工艺(HTCAP)和真空热压烧结工艺(VHPS)制备无定形碳(APC)/Al层状复合材料,研究葡萄糖溶液浓度对其显微组织、力学性能和摩擦学性能的影响。结果表明,APC在层间分布均匀,并且通过Al的扩散与基体形成良好的界面结合。随着葡萄糖溶液浓度的增加,层间硬度、极限抗拉强度(UTS)和伸长率先增大后减小,而磨损率则呈现相反的趋势,摩擦因数(COF)逐渐减小。当葡萄糖溶液浓度为0.3 mol/L时,伸长率最大,为16.4%,磨损率最小,为0.344×10^(-5)mm^(3)/(N·m)。粘着磨损是APC/Al层状复合材料的主要磨损机制。耐磨性的提高是由于在磨损表面形成均匀的APC润滑膜。

关键词：铝基层状复合材料无定形碳水热反应界面显微组织摩擦学性能

Molecular Biological and Biochemical Studies Reveal New Pathways Important for Cotton Fiber Development

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Journal of Integrative Plant Biology 2007年第1期49卷 69-74页

作者： yu xu hong-Bin Li yu-Xian Zhu National Laboratory of Protein Engineering and Plant Genetic Engineering Peking University Beijing 100871 China

As one of the longest single-celled seed trichomes, fibers provide an excellent model for studying fundamental biological processes such as cell differentiation, cell expansion, and cell wall biosynthesis. In this review, we summarize recent progress in cotton functional genomic studies that characterize the dynamic changes in the transcriptomes of fiber cells. Extensive expression profilings of cotton fiber transcriptomes have provided comprehensive information, as quite a number of transcription factors and enzyme-coding genes have been shown to express preferentially during the fiber elongation period. Biosynthesis of the plant hormone ethylene is found significantly upregulated during the fiber growth period as revealed by both microarray analysis and by biochemical and physiological studies. It is suggested that genetic engineering of the ethylene pathway may improve the quality and the productivity of cotton lint. Many metabolic pathways, such as biosynthesis of cellulose and matrix polysaccharides are preferentially expressed in actively growing fiber cells. Five gene families, including proline-rich proteins （PRP）, arabinogalactan proteins （AGP）, expansins, tubulins and lipid transfer proteins （LTP） are activated during early fiber development, indicating that they may also be needed for cell elongation. In conclusion, we identify a few areas of future research for cotton functional genomic studies.

关键词： cotton fiber functional genomics plant hormone transcriptome transcription factors

LES NUMERICAL SIMULATION OF CAVITATION BUBBLE SHEDDING ON ALE 25 AND ALE 15 HYDROFOILS

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Journal of Hydrodynamics 2009年第6期21卷 807-813页

作者： LIU De-min LIU Shu-hong WU yu-lin xu hong-yuan State Key Laboratory of Hydro Science and Hydraulic Engineering Department of Thermal Engineering Tsinghua University Beijing 100084 China

A cavitation calculation scheme is developed and applied to ALE 15 and ALE 25 hydrofoils, based on the Bubble Two-phase Flow （BTF） cavity model with a Large Eddy Simulation （LES） methodology. The Navier-Stokes equations including cavitation bubble clusters are solved through the finite-volume approach with a time-marching scheme. Simulations are carried out in a 3-D field with a hydrofoil ALE 15 or ALE 25 at an angle of attack of 8^0 and cavitation number σ = 2.3 with α 2× 10^6, meshing system. With the time-marching, the cavitation bubble gradually grows to a steady lump shape and then produces an irregular small bubble behind the main cavitation bubble, finally shedding from the leading edge of the cloud cavitation structure. The calculated results including velocity field and pressure field are consistent with experiment data at the same Reynolds number and cavitation number. The vortex and reverse flow are observed on the hydrofoil surface.

关键词： cavitation ALE hydrofoil Large Eddy Simulation (LES)

Temperature Effect on the Mechanical Behavior of Acrylic Polymers under Quasi-static and Dynamic Loading

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上海交通大学学报 2004年第z2期38卷 89-95页

作者： Tao Suo yulong Li hong yu Fei xu Zhongbin Tang Lei Li School of Aeronautics Northwestern Polytechnical University Xi''an710072 China School of Aeronautics Northwestern Polytechnical University Xi''an710072 China School of Aeronautics Northwestern Polytechnical University Xi''an710072 China School of Aeronautics Northwestern Polytechnical University Xi''an710072 China School of Aeronautics Northwestern Polytechnical University Xi''an710072 China Beijing Institute of Aeronautical Materials Beijing100095China

In this paper, the mechanical behavior of acrylic polymers at elevated temperature was investigated. Four acrylic polymers were tested at high strain rate by using compression Hopkinson bar and at quasi-static strain rate by using an Instron servo hydraulic axial testing machine with the testing temperature from 218K to 393K. The results show that the mechanical property of acrylic polymers depends heavily on the testing temperature. The yield stress and Young's modulus were found to decrease with increasing temperature at low strain rate. At very low temperature, the materials display typical brittle fracture; however their plasticity improves remarkably at high temperatures. The predictions of the mechanical behavior including the effect of temperature and strain rate using a proposed theoretical model have a good agreement with experimental results.

关键词： acrylic polymer compression Hopkinson bar quasi-static dynamic fracture

A Worst-Case Risk Measure by G-VaR

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Acta Mathematicae Applicatae Sinica 2021年第2期37卷 421-440页

作者： Zi-ting PEI Xi-shun WANG yu-hong xu Xing-ye yuE Center for Financial Engineering Soochow UniversitySuzhou 215006China Math Center for Interdiscipline Research Soochow UniversitySuzhou 215006China School of Mathematical Sciences Soochow UniversitySuzhou 215006China

G-VaR,which is a type of worst-case value-at-risk(VaR),is defined as measuring risk incorporating model *** with most extant notions of worst-case VaR,G-VaR can be computed using an explicit formula,and can be applied to large portfolios of several hundred dimensions with low computational *** also apply G-VaR to robust portfolio optimization,thereby providing a tractable means to facilitate optimal allocations under the condition of market ambiguity.

关键词： risk measurement worst-case value-at-risk portfolio management G-expectation

Thermal Behavior,Nonisothermal Decomposition Reaction Kinetics of Mixed Ester Double-base Gun Propellants

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Chemical Research in Chinese Universities 2008年第5期24卷 608-614页

作者： YI Jian-hua ZHAO Feng-qi xu Si-yu GAO hong-xu HU Rong-zu Xi＇an Modern Chemistry Research Institute Xi＇an 710065 P. R. China

The thermal decomposition behavior and nonisothermal reaction kinetics of the double-base gun propellants containing the mixed ester of triethyleneglycol dinitrate（TEGDN） and nitroglycerin（NG） were investigated by thermogravimetry（TG） and differential thermogravimetry（DTG）, and differential scanning calorimetry（DSC） under the high-pressure dynamic ambience. The results show that the thermal decomposition processes of the mixed nitric ester gun propellants have two mass-loss stages. Nitric ester evaporates and decomposes in the first stage, and nitrocellulose and centralite II（C2） decompose in the second stage. The mass loss, the DTG peak points, and the terminated temperatures of the two stages are changeable with the difference of the mass ratio of TEGDN to NG. There is only one obvious exothermic peak in the DSC curves under the different pressures. With the increase in the furnace pressure, the peak temperature decreases, and the decomposition heat increases. With the increase in the content of TEGDN, the decomposition heat decreases at 0.1 MPa and rises at high pressure. The variety of mass ratio of TEGDN to NG makes few effect on the exothermic peak temperatures in the DSC curves at different pressures. The kinetic equation of the main exothermal decomposition reaction of the gun propellant TG0601 was determined as： dα/dt=1021.59（1-α）3e-2.60×104/T. The reaction mechanism of the process can be classified as chemical reaction. The critical temperatures of the thermal explosion（Tbe and Tbp） obtained from the onset temperature（Te） and the peak temperature（Tp） are 456.46 and 473.40 K, respectively. ΔS≠, ΔH≠, and ΔG≠ of the decomposition reaction are 163.57 J·mol^-1·K^-1, 209.54 kJ·mol^-1, and 133.55 kJ·mol^-1, respectively.

关键词： Mixed nitric ester gun propellant Triethyleneglycol dinitrate Thermal behaviors Nonisothermal decomposition reaction kinetics

Identification of Quantitative Trait Loci for Grain Appearance and Milling Quality Using a Doubled-Haploid Rice Population

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Journal of Integrative Plant Biology 2005年第11期47卷 1391-1403页

作者： Gong-Hao JIANG xue-yu hong Cai-Guo xu Xiang-Hua LI yu-Qing HE State Key Laboratory of Crop Genetic Improvement and National Center of Crop Molecular Breeding Huazhong Agricultural University Wuhan 430070 China

Improving grain quality, which is composed primarily of the appearance of the grain and its cooking and milling attributes, is a major objective of many rice-producing areas in China. In the present study, we conducted a marker-based genetic analysis of the appearance and milling quality of rice （Oryza sativa L.） grains using a doubled-haploid population derived from a cross between the indica inbred Zhenshan 97 strain and the japonica inbred Wuyujing 2 strain. Quantitative trait locus （QTL） analysis using a mixed linear model approach revealed that the traits investigated were affected by one to seven QTLs that individually explained 4.0%-30.7% of the phenotypic variation. Cumulatively, the QTL for each trait explained from 12.9% to 61.4% of the phenotypic variation. Some QTLs tended to have a pleiotropic or location-linked association as a cause of the observed phenotypic correlations between different traits. Improvement of the characteristics of grain appearance and grain weight, as well as an improvement in the milling quality of rice grains, would be expected by a recombination of different QTLs using marker-assisted selection.

关键词： doubled-haploid population grain appearance quality grain milling quality Oryza sativa quantitative trait locus.