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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第5期19卷 354-363页

作者： Fang-fang WANG Jie-xue PAN Yan WU yu-hang zhu Paul J.HARDIMAN Fan QU Women's Hospital School of MedicineZhejiang UniversityHangzhou 310006China Reproductive Medicine Center the First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000China Institute for Women's Health University College London Medical SchoolLondonNW3 2PFUK

Polycystic ovary syndrome （PCOS） is the most common metabolic and endocrine disorder in women. However, there is no agreement concerning how to diagnose and treat PCOS worldwide. Three practice guidelines or consensuses, including consensus from the European Society of Human Reproduction and Embryology （ESHRE）/the American Society for Reproductive Medicine （ASRM） in Rotterdam, diagnosis criteria and consensus in China, and clinical practice guideline from the Endocrine Society （ES） in the United States are widely recognized. The present paper may provide some guidance for clinical practice based on a comparative analysis of the above three practice guidelines or consensuses.

关键词： Practice guideline Consensus Polycystic ovary syndrome

Circadian Rhythm Disruption In Ovarian Granulosa Cells In Polycystic Ovary Syndrome

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Constructing Donor–Acceptor‑Linked COFs Electrolytes to Regulate Electron Density and Accelerate the Li^(+)Migration in Quasi‑Solid‑State Battery

2016全国中西医结合妇产科研究进展学术研讨会暨2016年第一届江浙沪中西医结合妇产科高峰论坛

作者： yu-hang zhu Yan Wu Fan Qu Fang-Fang Wang Women’s Hospital School of MedicineZhejiang University

Background:Although the underlying etiology of polycystic ovary syndrome(PCOS)remains unclear,aberrant light-dark cycles greatly impair the ovarian *** continuous light exposure contributes to the development of PCOS in *** circadian rhythm disruption involved in the pathogenic mechanism of granulosa cells(GCs)dysfunction in PCOS?Materials and methods:Twelve PCOS patients and 25 women with tubal blockage undergoing in vitro fertilization(IVF) were *** GCs were collected during oocyte retrieval,and GCs were primarily *** performed quantitative realtime-PCR(qRT-PCR).Results:Using qRT-PCR,we identified the rhythmic mRNA expression of period 1(PERI),a core clock gene,and androgen receptor gene(AR) in serum-shocked GCs of controls with qRT-PCR,whereas the pattern of PERI and AR mRNA expression was disrupted in GCs of PCOS ***:Our findings indicate circadian rhythm disruption as a possible cause of GC dysfunction in ***: The GCs used in the present study were collected from patients undergoing IVF, thus it is of significance to further confirm our findings in unstimulated and non-luteinized GCs.

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Nano-Micro Letters 2025年第1期17卷 456-471页

作者： Genfu Zhao hang Ma Conghui Zhang Yongxin Yang Shuyuan yu Haiye zhu Yongjiang Sun Hong Guo School of Materials and Energy International Joint Research Center for Advanced Energy Materials of Yunnan ProvinceYunnan UniversityKunming 650091People’s Republic of China yunnan yuntianhua Co. LtdR&D CenterKunming 650228People’s Republic of China Southwest United Graduate School Kunming 650091People’s Republic of China

Regulation the electronic density of solid-state electrolyte by donor–acceptor(D–A)system can achieve highly-selective Li^(+)transportation and conduction in solid-state Li metal *** study reports a high-performance solid-state electrolyte thorough D–A-linked covalent organic frameworks(COFs)based on intramolecular charge transfer *** other reported COFbased solid-state electrolyte,the developed concept with D–A-linked COFs not only achieves electronic modulation to promote highly-selective Li^(+)migration and inhibit Li dendrite,but also offers a crucial opportunity to understand the role of electronic density in solid-state Li metal *** introduced strong electronegativity F-based ligand in COF electrolyte results in highlyselective Li^(+)(transference number 0.83),high ionic conductivity(6.7×10^(-4)S cm^(−1)),excellent cyclic ability(1000 h)in Li metal symmetric cell and high-capacity retention in Li/LiFePO_(4)cell(90.8%for 300 cycles at 5C)than substituted C-and N-based *** is ascribed to outstanding D–A interaction between donor porphyrin and acceptor F atoms,which effectively expedites electron transferring from porphyrin to F-based ligand and enhances Li^(+)***,we anticipate that this work creates insight into the strategy for accelerating Li^(+)conduction in high-performance solid-state Li metal batteries through D–A system.

关键词： Electronic modulation engineering Donor-acceptor-linked covalent organic frameworks Quasi-solid-state Li metal battery

Boosting bidirectional sulfur conversion enabled by introducing boron-doped atoms and phosphorus vacancies in Ni2P for lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 760-769页

作者： Lin Peng yu Bai hang Li Meixiu Qu Zhenhua Wang Kening Sun Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology Beijing Key Laboratory of Chemical Power Source and Green Catalysis School of Chemistry and Chemical Engineering Beijing Institute of Technology

Lithium-sulfur （Li-S） batteries have gained great attention due to the high theoretical energy density and low cost,yet their further commercialization has been obstructed by the notorious shuttle effect and sluggish redox ***,we supply a strategy to optimize the electron structure of Ni2P by concurrently introducing B-doped atoms and P vacancies in Ni2P （Vp-B-Ni2P）,thereby enhancing the bidirectional sulfur *** study indicates that the simultaneous introduction of B-doped atoms and P vacancies in Ni2P causes the redistribution of electron around Ni atoms,bringing about the upward shift of d-band center of Ni atoms and effective d-p orbital hybridization between Ni atoms and sulfur species,thus strengthening the chemical anchoring for lithium polysulfides （LiPSs） as well as expediting the bidirectional conversion kinetics of sulfur ***,theoretical calculations reveal that the incorporation of B-doped atoms and P vacancies in Ni2P selectively promotes Li2S dissolution and nucleation ***,the Li-S batteries with Vp-B-Ni2P-separators present outstanding rate ability of 777 m A h g-1at 5 C and high areal capacity of 8.03 mA h cm-2under E/S of 5μL mg-1and sulfur loading of 7.20 mg *** work elucidates that introducing heteroatom and vacancy in metal phosphide collaboratively regulates the electron structure to accelerate bidirectional sulfur conversion.

关键词： Lithium sulfur batteries

幽门螺旋杆菌和cagA阳性感染与食管炎的关系

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复旦学报（医学版） 2002年第4期29卷 317-318页

作者：戎兰孙大裕朱行蒋义斌复旦大学附属华山医院消化科上海200040

目的　研究幽门螺旋杆菌 (helicobacterpylori,Hp)和cagA表型与食管炎的关系。方法　选择胃镜诊断食管炎 (RE)、消化性溃疡 (PU)、慢性胃炎 (CG)者 ,活检组织均用尿素酶和Warren starr染色检测Hp ,用多聚酶链反应 (PCR)技术检测Hp菌株c... 详细信息

目的　研究幽门螺旋杆菌 (helicobacterpylori,Hp)和cagA表型与食管炎的关系。方法　选择胃镜诊断食管炎 (RE)、消化性溃疡 (PU)、慢性胃炎 (CG)者 ,活检组织均用尿素酶和Warren starr染色检测Hp ,用多聚酶链反应 (PCR)技术检测Hp菌株cagA基因。结果　Hp和cagA+ 在RE中感染率为 32 .4%、2 1.9% ,明显低于PU和CG(P <0 .0 0 1) ,cagA+ 感染率随RE的Ⅰ、Ⅱ分级降低 (P <0 .0 0 1)。Barrett食管炎者则无Hp感染。结论　Hp和cagA+

关键词：幽门螺旋杆菌 cagA阳性感染食管炎

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao Xiang Feng Gao yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

A new horizon for neuroscience:terahertz biotechnology in brain research

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Neural Regeneration Research 2025年第2期20卷 309-325页

作者： Zhengping Pu yu Wu Zhongjie zhu Hongwei Zhao Donghong Cui Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry Kangci Hospital of JiaxingTongxiangZhejiang ProvinceChina Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina Key Laboratory of Interfacial Physics and Technology Shanghai Institute of Applied PhysicsChinese Academy of ScienceShanghaiChina National Facility for Protein Science in Shanghai Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina

Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain *** this article,we review the development of terahertz biotechnology and its applications in the field of *** evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin *** vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric *** the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic ***,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical *** review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.

关键词： biological effect brain neuron neuropsychiatry neuroscience non-thermal effect terahertz imaging terahertz radiation terahertz spectroscopy terahertz technology

Low-cost and fluoride-free synthesis of MFI zeolite nanosheets with enhanced stability for benzene alkylation with ethanol

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Journal of Energy Chemistry 2025年第1期100卷 458-468页

作者： Peng zhu Cun Liu Yiren yu Guoshu Gao yumeng Zhao Xiongfu Zhang Guodong Liu Guohui Yang State Key Laboratory of Fine Chemicals School of Chemical Engineering Dalian University of Technology State Key Laboratory of Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences

Zeolite nanosheets with a short b-axis thickness are highly desirable in lots of catalytic reactions due to their reduced diffusion resistance. Nevertheless, conventional synthesis methods usually require expensive structure-directing agents(SDAs), pricey raw materials, and eco-unfriendly fluorine-containing additives. Here, we contributed a cost-effective and fluoride-free synthesis method for synthesizing high-quality MFI zeolite nanosheets through a Silicalite-1(Sil-1) seed suspension and urea cooperative strategy, only with inexpensive colloidal silica as the Si source. Our approach was effective for synthesizing both Sil-1 and aluminum-containing ZSM-5 nanosheets. By optimizing key synthesis parameters,including seed aging time, seed quantity, and urea concentration, we achieved precise control over the crystal face aspect ratio and b-axis thickness. We also revealed a non-classical oriented nanosheet growth mechanism, where Sil-1 seeds induced the formation of quasi-ordered precursor particles, and the(010)crystal planes of these particles facilitated urea adsorption, thereby promoting c-axis-oriented *** obtained ZSM-5 nanosheets exhibited exceptional catalytic performance in the benzene alkylation with ethanol, maintaining stability for over 500 h, which is 5 times longer than traditional ZSM-5 catalysts. Furthermore, large-scale production of ZSM-5 nanosheets was successfully carried out in a 3 L highpressure autoclave, yielding samples consistent with those from laboratory-scale synthesis. This work marks a significant step forward in the sustainable and efficient production of MFI nanosheets using inexpensive and environmentally friendly raw materials, offering the broad applicability in catalysis.

关键词： MFI zeolite ZSM-5 Nanosheets Scale-up synthesis Aromatic alkylation

考虑拉破坏的离散元双强度折减法的岩质边坡稳定性分析

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科学技术与工程 2016年第31期16卷 137-140页

作者：孙丹芳胡修文李雨朱杭琦中国地质大学工程学院武汉430074

岩质边坡在发生破坏时往往同时存在张拉破坏和剪切破坏。在考虑拉破坏的同时,结合双强度非等比例相关联折减法和强度折减的最短路径理论,改进了传统的双强度折减法,避免了以往双强度折减时选择比例系数的盲目性,所得的边坡稳定性系数更... 详细信息

岩质边坡在发生破坏时往往同时存在张拉破坏和剪切破坏。在考虑拉破坏的同时,结合双强度非等比例相关联折减法和强度折减的最短路径理论,改进了传统的双强度折减法,避免了以往双强度折减时选择比例系数的盲目性,所得的边坡稳定性系数更符合最小值理论。综合以上方法提出考虑拉破坏的离散元双强度折减法,并利用离散元软件udec对一顺层岩质边坡进行模拟。结果表明,该方法能够较好地反映边坡破坏过程中粘聚力与内摩擦角的发挥程度,所得稳定性系数与MP法所得结果更为接近,并且小于不考虑拉破坏时所得值。

关键词：岩质边坡拉破坏双强度折减法 udec

Transcutaneous electrical acupoint stimulation alleviates the anxiety levels of in vitro fertilization and improves the outcomes:a prospective,randomized and controlled study

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Transcutaneous electrical acupoint stimulation alleviates th...