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Chinese Journal of Chemical Engineering 2023年第12期64卷 188-195页

作者： yu-gao wang Xiao-Chen Han Bao Gu Hua-Shuai Wu Jun Shen School of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China

The fermentation for succinic acid production outperforms other methods by low energy consumption and environmental benignity,with the resulting products mainly as disodium succinate(DSA).By directly esterifying DSA using CO_(2) and CH3OH,it is expected to avoid the use of inorganic *** high-resolution mass spectrometry analysis and theoretical calculation,this study establishes that the reaction consists of three steps,i.e.,first forming 3-carboxypropanoate,then monomethyl succinate(MMS),and finally dimethyl succinate(DMS).A detailed kinetic analysis is further performed,the results demonstrate that the transformation of DSA to MMS is regarded to be a second-order reaction for reactant DSA,while the transformation of MMS to DMS is a first-order reaction for reactant *** activation energy for the generation of MMS from DSA is 37.15 kJ·mol^(-1),and that for the generation of DMS from MMS is 85.80 kJ·mol^(-1),indicating the latter one is the rate-determining step.

关键词： Succinate Carbon dioxide Direct esterification Reaction mechanism Reaction kinetics Kinetic modeling

Influence of Nitrogen Fertilizer and Endophyte Infection on Ecophysiological Parameters and Mineral Element Content of Perennial Ryegrass

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Journal of Integrative Plant Biology 2009年第1期51卷 75-83页

作者： An-Zhi Ren yu-Bao gao Wei wang Jin-Long wang Nian-Xi Zhao College of Life Science Nankai University Tianjin 300071 China

An experiment was designed to determine the effect of the fungal endophyte Neotyphodium Iolii on the growth, physiological parameters and mineral element content of perennial ryegrass （Lolium perennel L.）, when growing at two N supply levels. Endophyte infection had a significant positive effect on both shoot and root growth of ryegrass, but this difference was only significant in the high N supply treatment. At high N supply, endophyte-infected （El） plants accumulated more soluble sugar in the sheath and the root than endophyte-free （EF） plants. Endophyte infection affected mineral element concentrations in the root more than in the shoot. We found a significant effect of endophyte infection on B, Mn and Mg in the root, but significant effect was only found on B in the shoot. El plants tended to accumulate less B in the shoot at both N levels, but accumulated more B, Mn and Mg in the root at low N levels. The difference of growth parameters in different periods was significant. The content of soluble sugar and crude protein in the sheath were also dependent on the growth stages of both El and EF plants.

关键词： growth Lofiumperenne mineral element Neotyphodiumlolii nitrogen.

In-vitro Maturation of Immature Oocytes from Preantral Follicles in Prepuberal Mice

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Journal of Reproduction and Contraception 2007年第1期18卷 25-32页

作者： Min-zhi gao yu-bao wang Xiao-yun WU Shanghai Institute of Planned Parenthood Research Shanghai Bokang Reproductive Hospital Shanghai 200032China

Objective To observe the morphological changes in in vitro growth of preantral follicle isolated from prepuberal mice and to assess impacts of gonadotropin （Gn）, insulin transferrin selenium （ITS） and epidermal growth factor （EGF） on their development. Methods Early preantral mice follicles （90-130μm diameter） were mechanical isolated and selected from 2 weeks＇ old mice and then cultured in alpha-minimal essential medium （α-MEM） with or without Gn, ITS and EGF. The preantral follicles were cultured singly in 20 miovliters droplets for up to 14 d. The medium was replaced and the .follicles were observed everyday. Granulosa cells （GC） prolification, antrum formation and oocyte maturation were recorded. Results The medium with Gn supported preantral follicle culture in vitro, during which they retained a three-dimensional structure, maintained oocytes viability and increased in diameter and number of somatic cells＇. Preantral follicles cultured in Gn medium grew obviously, while those without Gn grew slowly and after 6 d＇s culture began to shrink and blacken. Significant increase in survival rate and maturation rate of oocytes was observed in Gn group （P〈0.01）, with 92.9% survived and 28.7%formed an antrum. Further supplementation of the Gn medium with ITS and rLH, resulted in the significant increase in survival and maturation of preantral follicle （P〈0.05） Conclusions α-MEM can be the medium for in vitro culture （IVC） of preantral follicles, but need to be added with rLH/rFSH, rHCG/rEGF to facilitate thecal cell attachment, GC proliferation and oocyte maturation.

关键词： in vitro culture in vitro maturation follicle development

Effect of pyrolysis on Zhaotong lignite oxidation with aqueous sodium hypochlorite

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Carbon Resources Conversion 2021年第1期4卷 1-9页

作者： yu-gao wang Chun-Hui Bo Jun Shen Zhi-Lei wang Yan-Xia Niu Xian-Yong Wei College of Chemistry and Chemical Engineering Taiyuan University of TechnologyTaiyuan 030024ShanxiChina State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering Yinchuan 750021NingxiaChina Key Laboratory of Coal Processing and Efficient Utilization Ministry of EducationChina University of Mining&TechnologyXuzhou 221116JiangsuChina

The pyrolysis treatment of lignites could remove thermal-unstable aliphatic structures but enrich aromatic structures in resulting pyrolysis residues,which would facilitate producing benzene polycarboxylic acids(BPCAs).Herein,the demineralized Zhaotong lignite(DZL)was pyrolyzed at 250-550℃ to afford the corresponding pyrolysis ***,DZL and its pyrolysis residues were subjected to oxidation with aqueous sodium *** XRD,FTIR,and element analyses,it was found that the content and polycondensation degree of aromatic structures simultaneously increased with increasing pyrolysis ***,the yield and selectivity of BPCAs both increased along with raising pyrolysis temperature in resulting products from fully oxidation of DZL and its pyrolysis *** on the distribution of BPCAs,peri-condensed aromatic structures were dominant in DZL and its DPRs,and obviously increased with increasing pyrolysis *** interestingly,good correlation was found between the yield of BPCAs and aromaticity ***,the yield of benzenepentacrboxylic acid was well associated with polycondensation degree parameters.

关键词： Pyrolysis Aqueous sodium hypochlorite Benzene polycarboxylic acids Lignite oxidation

A novel method for producing benzene polycarboxylic acids by electrochemical oxidation of Zhaotong lignite in aqueous NaCl solution

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Carbon Resources Conversion 2024年第2期7卷 88-94页

作者： Ze-Zheng Li Wei-Jia Jiang yu-gao wang Zhi-Lei wang Jun Shen Xian-Yong Wei College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024ShanxiChina School of Basic Medicine Shanxi University of Chinese MedicineJinzhong 030619China Institute of Environmental Science Shanxi UniversityTaiyuan 030031China Shanxi Huayang New Material Technology Group Co. Ltd.YangquanShanxi 045000China Key Laboratory of Coal Processing and Efficient Utilization Ministry of EducationChina University of Mining&TechnologyXuzhou 221116JiangsuChina

The development of a coal-based synthetic route to produce benzene polycarboxylic acids(BPCAs)is of great importance for the highly efficient utilization of *** this paper,aqueous NaCl^(-)electrolytic system was used to oxidize Zhaotong lignite to prepare *** electrochemical oxidation of lignite in aqueous NaCl solution could produce more BPCAs than that in aqueous NaOH *** aqueous NaCl electrolytic system could in-suit produce a stable OCl^(-),which was synthesized by the combination reaction between Cl_(2)and OH􀀀generated in the anode or cathode,*** in-suit produced OCl^(-)would degrade the organic structures of the lignite dispersing in the electrolyte to generate *** formation of BPCAs could be greatly affected by current density,electrolysis time and the addition amount of NaCl in the electrolytic system,which resulted from that the factors played an important role in the generation of OCl^(-).The coal related model compounds including anthracene and phenanthrene were used to investigate the electrochemical oxidation mechanism of the *** results indicated that the aromatic ring structures in the lignite were attacked by O_(2)•^(-)from the OCl^(-)to afford BPCAs.

关键词： Lignite Benzene polycarboxylic acids Electrochemical oxidation Aqueous NaCl electrolytic system Coal related model compounds

Male urethritis glandularis:case report

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Chinese Medical Journal 2007年第16期120卷 1460-1461页

作者： YIN Gang LIU yu-qiang gao Peng wang Xiao-hong Department of Urology Qilu Hospital Shandong University Jinan 250012 China

Urethritis glanduris is a rare benign inflammatory lesion and has a tendency to malignant transformation. We described here a case of urethritis glandularis with the extensive lesions in the anterior urethra and the s... 详细信息

关键词： urethritis urethral neoplasms adenocarcinoma

Using SEM to Verify the Impacts of Accumulated Intellectual Capital on Organizational Performance of Taiwan Listed Biotechnology Companies With the Moderator of Brand Equity

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Journal of Modern Accounting and Auditing 2012年第5期8卷 657-670页

作者： Lee yu-Je wang gao-Liang Wu Mei-Fen Takming University of Science and Technology Taiwan

The main purpose of this study is to verify the influence of accumulated Intellectual Capital （IC） on the organizational performance of biotechnology companies listed on the Taiwan Stock Exchange, with brand equity being the moderating variable. Financial and marketing section chiefs or employees of higher levels at Taiwan listed biotechnology companies were interviewed, with the companies＇ ROE （return on equity） data obtained from the Taiwan Economic Journal （TEJ） database. While convenience sampling was used to yield knowledge from the population, the linear Structural Equation Modeling （SEM） was adopted to verify the goodness-of-fit effects among the overall model, structural model, and measurement model. Findings from this study show that, at Taiwan listed biotechnology companies, IC accumulation and increased brand equity have significantly interactive influences on organizational performance.

关键词： intellectual capital (IC) organizational performance brand equity

Impact of chronic kidney disease on serum tumor markers concentrations

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Chinese Medical Journal 2013年第2期126卷 274-279页

作者： TONG Hong-li DONG Zhen-nan WEN Xin-yu gao Jing wang Bo TIAN Ya-ping Department of Clinical Biochemistry Chinese People's LiberationArmy General Hospital Beijing 100853 China

Background Serum tumor markers have always been of clinical importance in the diagnosis, monitoring disease progression and therapy efficacy for patients with malignant diseases. However, elevated serum tumor markers are found in some benign conditions, especially in chronic kidney disease （CKD）. The elevation of them in CKD might cause confusion and misuse of these tumor markers. We conducted this retrospective study to investigate which of the five widely used tumor markers including carcinoembryonic antigen （CEA）, alpha-fetoprotein （AFP）, cytokeratin 19 fragment antigen 21-1 （Cyfra21-1）, squamous cell carcinoma antigen （SCC） and neuron specific enolase （NSE） are affected markedly by CKD, in order to use them more effectively. Methods Serum tumor marker concentrations, biochemical, hematological parameters, and urinalysis were measured in CKD patients and healthy controls. The positive rate and median tumor markers＇ level in CKD patients and controls, and those in CKD patients stratified by CKD grade were compared using nonparametric rank tests. Correlation analysis of serum tumor markers and other parameters in CKD patients were performed using the Spearman correlation coefficient. Multivariate Logistic regression analysis was used to estimate the important variables that caused elevated serum concentrations of these markers in CKD patients. Results The overall positive rates and serum concentrations of Cyfra21-1, SCC, CEA in CKD group were significantly higher than those in control group. Positive rate and serum concentrations of those tumor markers increased as kidney function decreased. Both univariate analysis and multivariate regression analysis showed that the elevations of those tumor markers were not only associated with kidney function, but also with nutritional status. Conclusions Serum concentrations of Cyfra21-1, SCC, CEA are significantly influenced by kidney function, as well as nutritional status. Therefore, in clinical work, the indices of kidney

关键词： retrospective study kidney insufficiency tumor marker

具有均匀天空背景的高精度静态星模拟器设计（英文）

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光子学报 2016年第12期45卷 100-104页

作者：刘石张国玉孙高飞王凌云高玉军长春理工大学光电工程学院长春130022 吉林省光电测控仪器工程技术研究中心长春130022 中国科学院长春光学精密机械与物理研究所长春130022

为解决现有星模拟器只关注星图模拟精度而忽略天空背景模拟的问题,设计了具有均匀天空背景的高精度静态星模拟器.重点阐述星模拟器的组成和工作原理,详细论述光学系统优化设计方法.根据模拟器光学系统透镜大、精度高的特点,采用筒套筒... 详细信息

为解决现有星模拟器只关注星图模拟精度而忽略天空背景模拟的问题,设计了具有均匀天空背景的高精度静态星模拟器.重点阐述星模拟器的组成和工作原理,详细论述光学系统优化设计方法.根据模拟器光学系统透镜大、精度高的特点,采用筒套筒的镜筒设计形式;为了保证星图模拟精度,采用激光直写技术制作星点板,刻划精度优于±1μm.测试结果表明:设计的具有均匀天空背景的高精度静态星模拟器的星图模拟精度优于3″,天空背景均匀性优于95%,满足导航敏感器的高精度地面标定与功能测试需求.

关键词：光学设计静态星模拟器高精度星图模拟天空背景模拟

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： Xiao Xiang Feng gao yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states