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Development and application of photocatalytic coating for roadside NO_(x) mitigation in Hong Kong

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Chinese Chemical Letters 2024年第3期35卷 153-157页

作者： Xinwei Li Pengge Wang Shuwen Han yu Huang Wingkei Ho Steven Sai Hang Ho Shun-cheng lee Meng Wang Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina State Key Laboratory of Loess and Quaternary Geology(SKLLQG)and Key Laboratory of Aerosol Chemistry and Physics Institute of Earth EnvironmentChinese Academy of SciencesXi'an 710061China Department of Science and Environmental Studies The Education University of Hong KongHong KongChina Division of Atmospheric Sciences Desert Research InstituteRenoNV 89512United States

A facile chemical method for the development of photocatalytic coating products was proposed based on practical application perspective for the Hong Kong roadside nitrogen oxides(NO_(x))***_(2)-based photocatalytic coating PC-C film with crystallized size of around 5–6 nm was synthesized with the peptization of H_(2)O_(2).The PC-C coating possesses a super-hydrophilicity surface and is proven to have a NO_(x)degradation rate of 46.8%with an optimum pH level of *** addition,the PC-C coating presents a promising photocatalytic NO_(x)degradation compared with other commercially available coating products and P25 when applied on two building materials of poly-methyl methacrylate(PMMA)and concrete surface.A weather resistance simulation and a 180-day on-site field trial were carried out the attenuation effects of photocatalytic coating applied in outdoor *** on epidemiological estimation and field investigation,hospital admissions for respiratory diseases(HARD)and mortality cases(MC)could be reduced with the application of PC-C coating along the street *** work demonstrates the feasibility of air pollution control measures for the local roadside NO_(x)using photocatalytic technology,offering promising health benefits with environmental remediation.

关键词： Photocatalysis Coating NO_(x) mitigation Hong Kong Roadside

ATP6AP2,a regulator of LRP6/β-catenin protein trafficking,promotes Wnt/β-catenin signaling and bone formation in a cell type dependent manner

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Bone Research 2024年第2期12卷 453-468页

作者： Lei Xiong Hao-Han Guo Jin-Xiu Pan Xiao Ren Daehoon lee Li chen Lin Mei Wen-cheng Xiong Department of Neurosciences School of MedicineCase Western Reserve UniversityClevelandOH 44106USA Louis Stoke VA Medical Center ClevelandOH 44106USA

Wnt/β-catenin signaling is critical for various cellular processes in multiple cell types,including osteoblast(OB)differentiation and *** how Wnt/β-catenin signaling is regulated in OBs remain ***6AP2,an accessory subunit of V-ATPase,plays important roles in multiple cell types/organs and multiple signaling ***,little is known whether and how ATP6AP2 in OBs regulates Wnt/β-catenin signaling and bone *** we provide evidence for ATP6AP2 in the OB-lineage cells to promote OB-mediated bone formation and bone homeostasis selectively in the trabecular bone *** knocking out(CKO)ATP6AP2 in the OB-lineage cells(Atp6ap2^(Ocn-Cre))reduced trabecular,but not cortical,bone formation and bone *** and cellular biochemical studies revealed that LRP6 and N-cadherin were reduced in ATP6AP2-KO BMSCs and OBs,but not *** in vitro and in vivo studies revealed impairedβ-catenin signaling in ATP6AP2-KO BMSCs and OBs,but not osteocytes,under both basal and Wnt stimulated conditions,although LRP5 was decreased in ATP6AP2-KO osteocytes,but not *** cell biological studies uncovered that osteoblastic ATP6AP2 is not required for Wnt3a suppression ofβ-catenin phosphorylation,but necessary for LRP6/β-catenin and N-cadherin/β-catenin protein complex distribution at the cell membrane,thus preventing their *** of activeβ-catenin diminished the OB differentiation deficit in ATP6AP2-KO *** together,these results support the view for ATP6AP2 as a critical regulator of both LRP6 and N-cadherin protein trafficking and stability,and thus regulatingβ-catenin levels,demonstrating an un-recognized function of osteoblastic ATP6AP2 in promoting Wnt/LRP6/β-catenin signaling and trabecular bone formation.

关键词： LRP6 impaired organs

Comprehensive,Continuous,and Vertical Measurements of Seawater Constituents with Triple-Field-of-View High-Spectral-Resolution Lidar

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Research 2024年第2期2023卷 191-201页

作者： Kai Zhang Yatong chen Hongkai Zhao Zhongping lee Emmanuel Boss Iwona Stachlewska Davide Dionisi Cedric Jamet Paolo D.Girolamo Aleksey Malinka chengchong Jiang Hongda Wu Lingyun Wu Feitong chen Xiaolei Zhu Nanchao Wang Chuxiao chen Qun Liu Lan Wu yudi Zhou Weibiao chen Dong Liu Ningbo Research Institute State Key Laboratory of Modern Optical InstrumentationCollege of Optical Science and EngineeringZhejiang UniversityHangzhou 310027China ZJU-Hangzhou Global Scientific and Technological lnnovation Center Zhejang UniversityHangzhou 311200China Donghai Laboratory.Zhoushan 316021 China State Key Lab of Marine Environmental Science College of Ocean and Earth SciencesXiamen UniversityXiamen 361102China School of Marine Sciences University of MaineOronoME 04469-5741USA Faculty of Physics University of WarsawWarsaw 02093Poland institute of Marine Sciences Italian National Research CouncilRome 00133Italy Universitédu Littoral Cote d'Opale CNRSUniv.LilleIRDUMR 8187-LOG-Laboratoire d'Oceanologie et de GéosciencesWimereux F-6293 Francen Institute Scuola di Ingegneria Universita della BasilicataPotenza 85100Italy Institute of Physics National Academy of Sciences of BelarusMinsk 220072Belarus Key Laboratory of Space Laser Communication and Detection Technology Shanghai lnstitute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Inteligent Optics&Photonics Research Center Jiaxing Research Institute Zhejiang UniversityJiaxing 314000China Jiaxing Key Laboratory of Photonic Sensing&Intelligent Imaging Jiaxing 314000China

Measuring the characteristics of seawater constituent is in great demand for studies of marine ecosystems and ***,existing techniques based on remote sensing or in situ samplings present various tradeoffs with regard to the diversity,synchronism,temporal-spatial resolution,and depth-resolved capacity of their data ***,we demonstrate a novel oceanic triple-field-of-view(FOV)high-spectral-resolution lidar(HSRL)with an iterative retrieval *** technique provides,for the first time,comprehensive,continuous,and vertical measurements of seawater absorption coefficient,scattering coefficient,and slope of particle size distribution,which are validated by simulations and field ***,it depicts valuable application potentials in the accuracy improvement of seawater classification and the continuous estimation of depth-resolved particulate organic carbon *** triple-FOV HSRL with high performance could greatly increase the knowledge of seawater constituents and promote the understanding of marine ecosystems and biogeochemistry.

关键词： lidar Vertical seawater

Wavelength-interval switchable Brillouin–Raman random fiber laser through Brillouin pump manipulation

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Chinese Physics B 2024年第7期33卷 374-379页

作者：李阳徐恩明陈睿佳 yu-Gang Shee 张祖兴 Advanced Photonic Technology Laboratory College of Electronic and Optical Engineering&College of MicroelectronicsNanjing University of Posts and TelecommunicationsNanjing 210023China Department of Electrical and Electronic Engineering Lee Kong Chian Faculty of Engineering&Science(LKC FES)Universiti Tunku Abdul Rahman(UTAR)Sungai Long CampusMalaysia

A wavelength-interval switchable Brillouin–Raman random fiber laser(BRRFL) based on Brillouin pump(BP) manipulation is proposed in this paper. The proposed wavelength-interval switchable BRRFL has a full-open cavity configuration, featuring multiwavelength output with wavelength interval of double Brillouin frequency shifts. Through simultaneously injecting the BP light and its first-order stimulated Brillouin-scattered light into the cavity, the laser output exhibits a wavelength interval of single Brillouin frequency shift. The wavelength-interval switching effect can be manipulated by controlling the power of the first-order stimulated Brillouin scattering light. The experimental results show the multiwavelength output can be switched between double Brillouin frequency shift multiwavelength emission with a broad bandwidth of approximately 60 nm and single Brillouin frequency shift multiwavelength emission of 44 nm. The flexible optically controlled random fiber laser with switchable wavelength interval makes it useful for a wide range of applications and holds significant potential in the field of wavelength-division multiplexing optical communication.

关键词： wavelength-interval switchable fiber laser Brillouin fiber laser stimulated Brillouin-scattered random fiber laser

CD200Rhigghh neutrophils with dysfunctional autophagy establish systemic immunosuppression by increasing regulatory T cells

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Cellular & Molecular Immunology 2024年第4期21卷 349-361页

作者： Ye Seon Kim yu Sun Jeong Geon Ho Bae Ji Hyeon Kang Mingyu lee Brian A.Zabel Yoe-Sik Bae Department of Biological Sciences Sungkyunkwan UniversitySuwon16419Republic of Korea Department of Health Science and Technology SAIHSTSungkyunkwan UniversitySeoul06351Republic of Korea Palo Alto Veterans Institute for Research Veterans Affairs HospitalPalo AltoCA94304USA

Distinct neutrophil populations arise during certain pathological *** generation of dysfunctional neutrophils during sepsis and their contribution to septicemia-related systemic immune suppression remain *** this study,using an experimental sepsis model that features immunosuppression,we identified a novel population of pathogenic CD200R^(high) neutrophils that are generated during the initial stages of sepsis and contribute to systemic immune suppression by enhancing regulatory T(T_(reg))*** to their CD200R^(low)counterparts,sepsis-generated CD200Rhigh neutrophils exhibit impaired autophagy and dysfunction,with reduced chemotactic migration,superoxide anion production,and TNF-α*** soluble CD200 blocks autophagy and neutrophil maturation in the bone marrow during experimental sepsis,and recombinant CD200 treatment in vitro can induce neutrophil dysfunction similar to that observed in CD200R^(high) *** administration of anα-CD200R antibody effectively reversed neutrophil dysfunction by enhancing autophagy and protecting against a secondary infection challenge,leading to increased *** analysis revealed that CD200R^(high) neutrophils expressed high levels of Igf1,which elicits the generation of Treg cells,while the administration of anα-CD200R antibody inhibited Treg cell generation in a secondary infection *** together,our findings revealed a novel CD200R^(high) neutrophil population that mediates the pathogenesis of sepsis-induced systemic immunosuppression by generating Treg cells.

关键词： Sepsis Neutrophils CD200R Autophagy IGF-1 Regulatory T cells

Short- and long-term outcomes of surgical treatment in patients with intestinal Behcet’s disease

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 429-437页

作者： Min Young Park Yong Sik Yoon Jae Ha Park Jong Lyul lee Chang Sik yu Division of Colon and Rectal Surgery Department of SurgeryYonsei University College of MedicineSeoul 03722South Korea Division of Colon and Rectal Surgery Department of SurgeryUniversity of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea

BACKGROUND Behcet’s disease(BD),a chronic vasculitic disorder affecting multiple organs,is characterized by recurrent oral and genital ulcers,arthritis,vasculitis,and intes-tinal *** intestinal involvement of BD is common in East Asia,the efficacy and long-term outcomes of surgical treatment of intestinal BD still remain to be *** To evaluate the postoperative clinical course of intestinal BD and determine factors associated with its *** Data from patients who underwent surgical treatment for intestinal BD between January 2010 and August 2021 were retrospectively ***’demo-graphics,clinical features,postoperative course,complications,and follow-up data were *** We analyzed 39 surgeries in 31 *** mean patient age was 45.1 years,and the mean interval between the diagnosis of intestinal BD and surgical treatment was 4.9 years(range 1.0-8.0 years).The most common indication for surgery was medical intractability(n=16,41.0%),followed by fistula or abscess(n=11,28.2%).Laparoscopic approaches were used in 19 patients(48.7%),and 5 patients(12.8%)underwent emergency *** most common surgical procedure was ileocecal resection(n=18,46.2%),followed by right colectomy(n=11,28.2%).A diverting stoma was created in only one patient(2.6%).During a mean follow-up period of 45(range 8-72)months,eight cases(20.5%)of recurrence in five patients required *** interval between operations was 12.1 months(range 6.3-17.8 mo).Four patients(10.3%)experienced recurrence within 1 year postoperatively,and all eight recurrences occurred within 2 years of the initial *** reoperation rates at 1 and 3 years were 10.3%and 20.5%,respectively.A redo ileocolic anastomosis was performed in all recurrent *** multivariate Cox regression analysis,emergency surgery[hazard ratio(HR)9.357,95%confidence interval(CI):1.608-54.453,P=0.013]and elevated C-reactive protein(CRP)levels(HR 1.154,95%CI:1.002–1.328,

关键词： Behcet syndrome Intestinal General surgery Recurrence Risk factors

Characteristics of Traditional Chinese Medicine Use in Patients with Rheumatoid Arthritis in Taiwan:a Nationwide Population-Based Study

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Characteristics of Traditional Chinese Medicine Use in Patie...

Enhancing Identity Protection in Metaverse-Based Psychological Counseling System

第十四届全国中药和天然药物学术研讨会

作者： Ming-cheng Huang Fu-Tzu Pai Hen-Hong Chang Hung-Rong Yen yu-chen lee Mao-Feng Sun China Medical University Hospital Chang Gung University China Medical University

Objective Nationwide study of current traditional Chinese medicine（TCM） usage trend among patients with rheumatoid arthritis（RA） is *** aim of this study is to evaluate the application of TCM among RA patients in *** and Methods This study examined datasets from the National Health Insurance Research Database in ***（n=25,263） newly diagnosed as RA and proven as catastrophic illness commissioned by rheumatologists between January 2001 and December 2009 were included in this *** who had at least one TCM outpatient clinical record were defined as TCM users（n=6981）,whereas those without TCM outpatient records were defined as non-TCM users（n=18372）.The demographic data,treatment modalities,disease distributions,comorbidities,and prescription pattern of the TCM users were *** TCM users were younger than non-TCM user（mean age:49.6 versus 54.0）.The ratio of female to male in TCM users was higher than non-TCM users（5:1 vs.3:1）.The average interval between RA onset and the first TCM clinical visit was 23.4 *** remedies were the most commonly used therapeutic approach（76.4%）,followed by combined herbal remedies and acupuncture（21.1%）,and acupuncture or traumatology alone（2.5%）.The most commonly prescribed formulas were Shang-Zhong-Xia-Tong-Yong-Tong-Feng-Wan,Jia-Wei-Xiao-Yao-San and Liu-Wei-Di-Huang-Wan,whereas Rhizoma Corydalis,Radix Clematidis and Caulis Spatholobi were the three most frequently prescribed single *** who had allergic rhinitis,disorders of menstruation or anxiety and depression were prone to have more TCM visits compared to non-TCM *** Our population-based study revealed the high prevalence and specific usage patterns of TCM in the RA patients in *** results provided valuable information for further pharmacologic investigation and clinical studies on the treatment of RA.

关键词： Complementary and alternative medicine National Health Insurance Database Rheumatoid arthritis Traditional Chinese medicine

来源： cnki会议评论

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Computers, Materials & Continua 2024年第1期78卷 617-632页

作者： Jun lee Hanna lee Seong Chan lee Hyun Kwon Department of Game Software Hoseo UniversityAsan-si31499Korea Yatav Enter Seoul04799Korea Department of Artificial Intelligence and Data Science Korea Military AcademySeoul01805Korea

Non-face-to-face psychological counseling systems rely on network technologies to anonymize information regard-ing client ***,these systems often face challenges concerning voice data leaks and the suboptimal communication of the client’s non-verbal expressions,such as facial cues,to the *** study proposes a metaverse-based psychological counseling system designed to enhance client identity protection while ensuring efficient information delivery to counselors during non-face-to-face *** proposed systemincorporates a voicemodulation function that instantlymodifies/masks the client’s voice to safeguard their ***,it employs real-time client facial expression recognition using an ensemble of decision trees to mirror the client’s non-verbal expressions through their avatar in the metaverse *** system is adaptable for use on personal computers and smartphones,offering users the flexibility to access metaverse-based psychological counseling across diverse *** performance evaluation of the proposed system confirmed that the voice modulation and real-time facial expression replication consistently achieve an average speed of 48.32 frames per second or higher,even when tested on the least powerful smartphone ***,a total of 550 actual psychological counseling sessions were conducted,and the average satisfaction rating reached 4.46 on a 5-point *** indicates that clients experienced improved identity protection compared to conventional non-face-to-face metaverse counseling ***,the counselor successfully addressed the challenge of conveying non-verbal cues from clients who typically struggled with non-face-to-face psychological *** proposed systemholds significant potential for applications in interactive discussions and educational activities in the metaverse.

关键词： Metaverse counseling system face tracking identity protection

Generalized polynomial chaos expansion by reanalysis using static condensation based on substructuring

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Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 819-836页

作者： D.lee S.CHANG J.lee Department of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea School of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea Department of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This paper presents a new computational method for forward uncertainty quantification(UQ)analyses on large-scale structural systems in the presence of arbitrary and dependent random *** method consists of a generalized polynomial chaos expansion(GPCE)for statistical moment and reliability analyses associated with the stochastic output and a static reanalysis method to generate the input-output data *** the reanalysis,we employ substructuring for a structure to isolate its local regions that vary due to random *** allows for avoiding repeated computations of invariant substructures while generating the input-output data *** substructuring with static condensation further improves the computational efficiency of the reanalysis without losing ***,the GPCE with the static reanalysis method can achieve significant computational saving,thus mitigating the curse of dimensionality to some degree for UQ under high-dimensional *** numerical results obtained from a simple structure indicate that the proposed method for UQ produces accurate solutions more efficiently than the GPCE using full finite element analyses(FEAs).We also demonstrate the efficiency and scalability of the proposed method by executing UQ for a large-scale wing-box structure under ten-dimensional(all-dependent)random inputs.

关键词： forward uncertainty quantification(UQ) generalized polynomial chaos expansion(GPCE) static reanalysis method static condensation substructuring