检索结果-南通市图书馆

A Comprehensive Study for Its Application in Asymmetric AdaBoost and Object Detection

自动化学报 2009年第11期35卷 1403-1409页

作者： GE Jun-Feng luo yu-Pin Tsinghua National Laboratory for Information Science and Tech-nology(TNList) Department of Automation Tsinghua UniversityBeijing 100084 P. R. China

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular medicine of fragile X syndrome: based on known molecular mechanisms

引用

World Journal of Pediatrics 2016年第1期12卷 19-27页

作者： Shi-yu luo Ling-Qian Wu Ran-Hui Duan State Key Laboratory of Medical Genetics&School of Life Sciences Central South UniversityChangshaChina

Background:Extensive research on fragile X mental retardation gene knockout mice and mutant Drosophila models has largely expanded our knowledge on mechanism-based treatment of fragile X syndrome(FXS).In light of these findings,several clinical trials are now underway for therapeutic translation to *** sources:Electronic literature searches were conducted using the PubMed database and *** search terms included"fragile X syndrome","FXS and medication","FXS and therapeutics"and"FXS and treatment".Based on the publications identified in this search,we reviewed the neuroanatomical abnormalities in FXS patients and the potential pathogenic mechanisms to monitor the progress of FXS research,from basic studies to clinical ***:The pathological mechanisms of FXS were categorized on the basis of neuroanatomy,synaptic structure,synaptic transmission and fragile X mental retardation protein(FMRP)loss of *** neuroanatomical abnormalities in FXS were described to motivate extensive research into the region-specific pathologies in the brain responsible for FXS behavioural ***-directed molecular medicines were classified according to their target pathological mechanisms,and the most recent progress in clinical trials was ***:Current mechanism-based studies and clinical trials have greatly contributed to the development of FXS pharmacological *** examining the extent to which these treatments provided a rescue effect or FMRP compensation for the developmental impairments in FXS patients may help to improve the effi cacy of treatments.

关键词： clinical trial fragile X syndrome mechanism-based treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Control of gallbladder contractions by cholecystokinin through cholecystokinin-A receptors on gallbladder interstitial cells of cajal

引用

World Journal of Gastroenterology 2008年第18期14卷 2882-2887页

作者： Dan Xu Bao-Ping yu He-Sheng luo Ling-Dan Chen Department of Gastroenterology Renmin Hospital of Wuhan University Wuhan 430060 Hubei Province China

AIM: To identify the cholecystokinin (CCK)-A receptors (CCK-AR) on the guniea pig gallbladder interstitial cells of cajal (ICC) and to study CCK-8 induced gallbladder muscle strip contractions through the CCK-AR. METHODS: The existence of CCK-AR was examined by immunohistofluorescence on sectioned tissue and cultured cells. In vitro contractile response of guinea pig gallbladder muscle strips and the strips with ICC removed were also studied with CCK-8 receptors added. RESULTS: In tissue sections, intensely CCKAR- immunoreactive interstitial cells were found mainly in the muscular layers. In cultured cell sections, distinctive double staining of C-kit and CCK-AR ICCs were found. When we removed the ICC of the gallbladder, CCK-8 induced muscle strip contraction dose response curve significantly shifted to the right. CONCLUSION: We proved that both the existence of CCK-AR on the guinea pig gallbladder ICC and CCK evoked contraction are mediated through direct action on CCK-AR on the gallbladder ICC.

关键词： Gallbladder Interstitial cells of cajal Cholecystokinin-A receptor C-kit Immunohistofluorescence

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantitative Evaluation of Sustainable Development and Eco-Environmental Carrying Capacity in Water-Deficient Regions:A Case Study in the Haihe River Basin,China

引用

Journal of Integrative Agriculture 2014年第1期13卷 195-206页

作者： WANG Zhong-gen luo yu-zhou ZHANG Ming-hua XIA Jun Key Laboratory of Water Cycle & Related Land Surface Processes/Institute of Geographical Science and Natural Resources Research Chinese Academy of Sciences Department of Land Air and Water ResourcesUniversity of California

Quantitative assessment of development sustainability could be a challenge to regional management and planning, especially for areas facing great risks of water shortage. Surface-water decline and groundwater over-pumping have caused serious environmental problems and limited economic development in many regions all around the world. In this paper, a framework for quantitatively evaluating development sustainability was established with water-related eco-environmental carrying capacity （EECC） as the core measure. As a case study, the developed approach was applied to data of the Haihe River Basin, China, during 1998 through 2007. The overall sustainable development degree （SDD） is determined to be 0.39, suggesting that this rate of development is not sustainable. Results of scenario analysis revealed that overshoot, or resource over- exploitation, of the Basin＇s EECC is about 20% for both population and economy. Based on conditions in the study area in 2007, in order to achieve sustainable development, i.e., SDD〉0.70 in this study, the EECC could support a population of 108 million and gross domestic product （GDP） of 2.72 trillion CNY. The newly developed approach in quantifying ecoenvironmental carrying capacity is anticipated to facilitate sustainable development oriented resource management in waterdeficient areas.

关键词： eco-environmental carrying capacity development scenario Haihe River Basin sustainable development waterresources

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A new member of the calix[4]crown family:Facile synthesis and characterization of a calix[4]crown-9 cone conformer

引用

Chinese Chemical Letters 2009年第2期20卷 143-146页

作者： Hao Hui Zhou Xian Mei Shang Zhi luo yu Xiang Xia Jun luo Guang Ya Xiang Tongji School of Pharmacy Huazhong University of Science and Technology Wuhan 430030 China

25,27-Dipropoxy-p-tert-butylcalix[4]crown-9 cone conformer 5 was readily synthesized via an intramolecular cyclization strategy in good yields. The structures of all the new compounds involved were confirmed by NMR, E... 详细信息

关键词： Calixcrown-9 Cone conformation Synthesis Intramolecular cyclization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Facile Synthesis and High-Value Utilization of Ammonia

引用

Chinese Journal of Chemistry 2022年第8期40卷 953-964页

作者： yu luo Shijing Liang Xiuyun Wang Bingyu Lin Chongqi Chen Lilong Jiang National Engineering Research Center of Chemical Fertilizer Catalyst Fuzhou UniversityFuzhouFujian 350002China Qingyuan Innovation Laboratory QuanzhouFujian 362801China

Ammonia is a key component in fertilizer and the carbon-free hydrogen *** ammonia synthesis and utilization have played a central role in the development of chemical *** industrial production of ammonia remains dependent on the energy-and carbon-intensive Haber-Bosch process.A major effort has been devoted to developing robust and efficient catalysts,as well as alternative benign ***,we detail our endeavors that develop the ammonia synthesis and decomposition catalysts,and utilize the ammonia *** firstly discuss the catalysts for ammonia synthesis via dissociative and associative process,and the regulation of catalysts'***,we review the burgeoning electrocata-lytic nitrogen reduction process,focusing on the enhanced catalytic performances by the regulation of the catalysts and the ***,we provide a novel high-value utilization of ammonia to achieve the"zero-carbon"circular *** promising catalysts,reactors,and ammonia energy systems have been discussed in *** end this Account that offers future research directions and prospects of ammonia.

关键词： Nitrogen fixation Ammonia-to-hydrogen Carbon-free Heterogeneous catalysis Supported catalysts

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An improved algorithm based on equivalent sound velocity profile method at large incident angle

引用

Acta Oceanologica Sinica 2024年第2期43卷 161-167页

作者： Qianqian Li Qian Tong Fanlin Yang Qi Li Zhihao Juan yu luo College of Geodesy and Geomatics Shandong University of Science and TechnologyQingdao 266590China College of Underwater Acoustic Engineering Harbin Engineering UniversityHarbin 150001China

With the development of ultra-wide coverage technology,multibeam echo-sounder(MBES)system has put forward higher requirements for localization accuracy and computational efficiency of ray tracing *** classical equivalent sound speed profile(ESSP)method replaces the measured sound velocity profile(SVP)with a simple constant gradient SVP,reducing the computational workload of beam ***,in deep-sea environment,the depth measurement error of this method rapidly increases from the central beam to the edge *** analyzing the positioning error of the ESSP method at edge beam,it is discovered that the positioning error increases monotonically with the incident angle,and the relationship between them could be expressed by polynomial ***,an error correction algorithm based on polynomial fitting is *** simulation experiment conducted on an inclined seafloor shows that the proposed algorithm exhibits comparable efficiency to the original ESSP method,while significantly improving bathymetry accuracy by nearly eight times in the edge beam.

关键词： equivalent sound speed profile ray tracing method large incident angle edge beam deep sea error correction multibeam echo-sounder system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Full-parameter omnidirectional transformation optical devices

引用

National Science Review 2024年第3期11卷 92-99页

作者： yuan Gao yu luo Jingjing Zhang Zhengjie Huang Bin Zheng Hongsheng Chen Dexin Ye Interdisciplinary Center for Quantum Information State Key Laboratory of Extreme Photonics and InstrumentationZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang University School of Electrical and Electronic Engineering Nanyang Technological University CNRS-InternationalNTU-Thales Research Alliance Nanyang Technological University Institute of Electromagnetic Space Southeast University State Key Laboratory of Millimeter Waves Southeast University International Joint Innovation Center The Electromagnetics Academy at Zhejiang University Zhejiang University Key Laboratory of Advanced Micro/Nano Electronic Devices&Smart Systems of Zhejiang Jinhua Institute of Zhejiang UniversityZhejiang University Shaoxing Institute of Zhejiang University Zhejiang University

Transformation optics(TO) provides an unprecedented technique to control electromagnetic(EM) waves by engineering the constitutive parameters of the surrounding medium through a proper spatial transformation. In general, ideal transformation optical devices require simultaneous electric and magnetic responses along all three dimensions. To ease the practical implementation, previous studies usually made use of reduced parameters or other simplified approaches, which inevitably introduce extra reflection or unwanted phase shift. Up to today, experimental realizations of full-parameter transformation optical devices in free space are still quite limited. Here, a general design strategy is proposed to solve this *** a specific example, a full-parameter spatial-compression TO medium with constitutive parameters taking the diagonal form diag(a, a, 1/a) for the TM wave incidence was designed and realized experimentally. Such spatial-compression TO media were then applied to the implementation of an ideal omnidirectional invisibility cloak capable of concealing a large-scale object over a wide range of illumination angles. Both the simulation and experiment confirm that the cloak allows for nearly unity transmission of EM waves in the forward direction without introducing extra scattering or phase shift. This work constitutes an important stepping stone for future practical implementation of arbitrary full-parameter omnidirectional transformation optical devices.

关键词： transformation optical devices omnidirectional impedance matching full-parameter invisibility cloak

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Hypoglycemic effect and the mechanism of action of a polysaccharide from sweet corncob in a high-fat diet and streptozotocin-induced diabetic mice

引用

Food Science and Human Wellness 2024年第3期13卷 1543-1555页

作者： Xin Wang Weiye Xiu Ye Han Zhili Wang yu luo Yongqiang Ma Heilongjiang Provincial Key Laboratory of Cereals and Comprehensive Processing of Cereal Resources College of Food EngineeringHarbin University of CommerceHarbin 150028China

Type 2 diabetes mellitus(T2DM)is a metabolic disease caused by a glycolipid metabolism disorder and isletβ-cell ***-80-I is a biologically active water-soluble polysaccharide isolated from sweet corncob,an agricultural *** hypoglycemic effects of SCP-80-I on T2DM mice and its mechanisms were investigated in this ***-80-I was found to significantly reduce blood glucose and lipid deposition levels in T2DM mice,as well as decrease serum leptin and increase adiponectin ***,real time-polymerase chain reaction(RT-PCR)and Western blotting results revealed that SCP-80-I could regulate the expression of several glycolipid metabolisms and insulin secretion genes and proteins,including 5'-AMP-activated protein kinase(AMPK),carnitine palmitoyltransferase I(CPTI),and acetyl coenzyme A carboxylase(ACC)in the liver and AMPK,sirtuin1(Sirtl),peroxisome proliferator-activated receptorycoactivator-1(PGC-1α),and uncoupling protein 2(UCP2)in the *** have a hypoglycemic effect,SCP-80-1 regulated glycolipid metabolism and islet cell function in the liver by regulating the AMPK/AC C/CPT1 signaling pathway and the AMPK/Sirt1/PGC-1αand AMPK/Sirtl/UCP2 signaling *** findings improve our understanding of polysaccharides derived from sweet corncob and the use of SCP-80-I in the production of hypoglycemic foods.

关键词： Sweet corn cob polysaccharide Type 2 diabetes Signal pathway 5’-AMP-activated protein kinase(AMPK)

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Quantitative proteomics reveals key pathways in the symbiotic interface and the likely extracellular property of soybean symbiosome

引用

Journal of Genetics and Genomics 2023年第1期50卷 7-19页

作者： yu luo Wei Liu Juan Sun Zheng-Rong Zhang Wei-Cai Yang The State Key Laboratory for Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China

An effective symbiosis between legumes and rhizobia relies largely on diverse proteins at the plantrhizobium interface for material transportation and signal transduction during symbiotic nitrogen ***,we report a comprehensive proteome atlas of the soybean symbiosome membrane(SM),peribacteroid space(PBS),and root microsomal fraction(RMF)using state-of-the-art label-free quantitative proteomic *** total,1759 soybean proteins with diverse functions are detected in the SM,and 1476 soybean proteins and 369 rhizobial proteins are detected in the *** diversity of SM proteins detected suggests multiple origins of the *** comparative analysis highlights amino acid metabolism and nutrient uptake in the SM,indicative of the key pathways in nitrogen *** detection of soybean secretory proteins in the PBS and receptor-like kinases in the SM provides evidence for the likely extracellular property of the symbiosome and the potential signaling communication between both symbionts at the symbiotic *** proteomic data provide clues for how some of the sophisticated regulation between soybean and rhizobium at the symbiotic interface is achieved,and suggest approaches for symbiosis engineering.

关键词： Quantitative proteomics Symbiotic nitrogen fixation Symbiosome membrane Peribacteroid space Soybean

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：