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Clinical effect of laparoscopic radical resection of colorectal cancer based on propensity score matching

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 124-133页

作者： Yang liu Xian-Xue Wang yu-lin li Wen-Tao He Hong li Hua Chen Department of General Surgery Changde HospitalXiangya School of MedicineCentral South University(The First People’s Hospital of Changde City)Changde 415000Hunan ProvinceChina Department of Anesthesiology Changde HospitalXiangya School of MedicineCentral South University(The First People’s Hospital of Changde City)Changde 415000Hunan ProvinceChina

BACKGROUND The incidence of colorectal cancer(CRC)is increasing *** radical resection of CRC is a minimally invasive procedure preferred in clinical *** To investigate the clinical effect of laparoscopic radical resection of CRC on the basis of propensity score matching(PSM).METHODS The clinical data of 100 patients who received inpatient treatment for CRC at Changde Hospital,Xiangya School of Medicine,Central South University(The First People’s Hospital of Changde City)were analyzed *** control group included patients who underwent open surgery(n=43),and those who underwent laparoscopic surgery formed the observation group(n=57).The baseline information of both groups was equipoised using 1×1 *** in the perioperative parameters,inflammatory response,immune function,degree of pain,and physical status between the groups were *** Thirty patients from both groups were successfully *** PSM,baseline data showed no statistically significant differences between the groups:(1)Periop-erative parameters:The observation group had a longer surgery time,less intra-operative blood loss,earlier first ambulation and first anal exhaust times,and shorter gastric tube indwelling time than the control group;(2)Inflammatory response:24 h after surgery,the levels of interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-α(TNF-α)between groups were higher than ***-6,CRP,and TNF-αlevels in the observation group were lower than in the control group;(3)Immune function:At 24 h after surgery,counts of CD4-positive T-lymphocytes(CD4+)and CD4+/CD8-positive T-lymphocytes(CD8+)in both groups were lower than those before surgery,whereas CD8+was higher than that before *** 24 h after surgery,both CD4+counts and CD4+/CD8+in the observation group were higher than those in the control group,whereas CD8+counts were lower;(4)Degree of pain:The visual analog scale scores in the observation gro

关键词： Colorectal cancer Laparoscopic Open surgery Inflammatory reaction Immune function Propensity score

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基于变异的正则表达式反例测试串生成算法

软件学报 2024年第7期35卷 3355-3376页

作者：郑黎晓余李林陈海明陈祖希骆翔宇汪小勇华侨大学计算机科学与技术学院福建厦门361021 计算机科学国家重点实验室(中国科学院软件研究所) 北京100190 卡斯柯信号有限公司上海200070

正则表达式在计算机科学的许多领域具有广泛应用.然而,由于正则表达式语法比较复杂,并且允许使用大量元字符,导致开发人员在定义和使用时容易出错.测试是保证正则表达式语义正确性的实用和有效手段,常用的方法是根据被测表达式生成一些... 详细信息

正则表达式在计算机科学的许多领域具有广泛应用.然而,由于正则表达式语法比较复杂,并且允许使用大量元字符,导致开发人员在定义和使用时容易出错.测试是保证正则表达式语义正确性的实用和有效手段,常用的方法是根据被测表达式生成一些字符串,并检查它们是否符合预期.现有的测试数据生成大多只关注正例串,而研究表明,实际开发中存在的错误大部分在于定义的语言比预期语言小,这类错误只能通过反例串才能发现.研究基于变异的正则表达式反例测试串生成.首先通过变异向被测表达式中注入缺陷得到一组变异体,然后在被测表达式所定义语言的补集中选取反例字符串揭示相应变异体所模拟的错误.为了能够模拟复杂缺陷类型,以及避免出现变异体特化而无法获得反例串的问题,引入二阶变异机制.同时采取冗余变异体消除、变异算子选择等优化技术对变异体进行约简,从而控制最终生成的测试集规模.实验结果表明,与已有工具相比,所提算法生成的反例测试串规模适中,并且具有较强的揭示错误能力.

关键词：正则表达式正则语言字符串生成变异测试变异体约简

First Total Synthesis of 6-Oxodendrolasinolide

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Chinese Chemical Letters 2006年第2期17卷 147-149页

作者： Yi li Tao ZHANG yu lin li State Key Laboratory of Applied Organic Chemistry Institute of organic chemistry Lanzhou University Lanzhou 730000 Minsheng Group Shaoxing Pharmaceutical Co. Ltd. Shaoxing 312071

An efficient total synthesis of 6-oxodendrolasinolide 1, a new farnesane-based homosesquiterpene lactone, starting from geraniol 2 through twelve steps is described. Our work involved two key steps：（1） regioselective alkylation of the anion of vinyldithian 5 with allylic chloride 31, （2） Corey＇s oxidative lactionization method2.

关键词： Total synthesis butenolide homosesquiterpene.

The First Total Synthesis of Saurufuran B

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Chinese Chemical Letters 2006年第10期17卷 1287-1289页

作者： Yi Hua YANG yu lin li State Key Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry Lanzhou University Lanzhou 730000

First total synthesis of saurufuran B 1, a furanoditerpene, from （E, E）-farnesol 2 and citraconic anhydride 3 through thirteen steps is described. Our work involves two key steps：（1） High regioselective alkylation of 2-（tert-butyldimethylsiloxy）-4-methylfuran 6 with aUylic iodides 5 in the presence of silver wifluoroacetate and （2） Conversion of substituted 7-1actone 7 into furan derivative 8.

关键词： Saurufuran B first total synthesis furanoditerpene regioselective alkylation.

Manganese Dioxide with High Specific Surface Area for Alkaline Battery

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Chemical Research in Chinese Universities 2012年第5期28卷 874-877页

作者： HUANG You-ju lin yu-li li Wei-shan School of Chemistry and Environment Ministry of EducationSouth China Normal UniversityGuangzhou 510006P.R.China Key Laboratory of Electrochemical Technology on Energy Storage and Power Generation of Guangdong Higher Education Institutes Ministry of EducationSouth China Normal UniversityGuangzhou 510006P.R.China Engineering Research Center of Materials and Technology for Electrochemical Energy Storage Ministry of EducationSouth China Normal UniversityGuangzhou 510006P.R.China

The authors reported a facile method for the synthesis of manganese dioxide without any template and catalyst at a low-temperature. The prepared sample was characterized with X-ray diffraction（XRD）, scanning electron microscopy（SEM）, Brunauer-Emmett-Teller（BET） surface analysis, Fourier transform infrared（FTIR） spectrometry, cyclic voltammetry, alternative current（AC） impedance test and battery discharge test. It is found that the prepared sample belongs to α-MnO2 and has a microsphere morphology and a large BET surface area. The electrochemical characterization indicates that the prepared sample displays a larger electrochemical capacitance than the commercial electrolytic manganese dioxides（EMD） in Na2SO4 solution, and exhibits larger discharge capacity than EMD, especially at a high rate discharge condition when it is used as cathode of alkaline Zn/MnO2 battery.

关键词： Manganese dioxide Rate performance Cathode material Alkaline battery

First Total Synthesis of 5_α-Hydroxy-isopterocarpolone

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Chinese Chemical Letters 2001年第5期12卷 407-408页

作者： Gang ZHOU Xiao Lei GAO yu Kun GUAN Wei Dong li yu lin li National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry Lanzhou UniversityLanzhou 730000

The first total synthesis of 5α-hydroxy-isopterocarpolone has been described.

关键词： Total synthesis 5α-hydroxy-isopterocarpolone.

Baker's Yeast Mediated Reduction of Optically Active Diketone

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Chinese Chemical Letters 2001年第4期12卷 291-292页

作者： Xiao Lei GAO Gang ZHOU yu Kun GUAN Wei Dong li yu lin li National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry Lanzhou UniversityLanzhou 730000

Baker's Yeast mediated reduction of optically active diketone has been described.

关键词： Baker’s yeast reduction optically active diketone

Studies on the Total Synthesis of Crotocembreneic Acid and Neocrotocembreneic Acid:A Perchloric Acid-induced Lactonization Reaction of Epoxy Ester

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Chinese Chemical Letters 2000年第10期11卷 871-872页

作者： Zuo Sheng liU Jiong LAN li Zeng PENG yu lin li National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry Lanzhou UniversityLanzhou 730000

A perchoric acid-induced lactonization reaction of epoxy ester is described. Using lithium perchlorate, the ketone is obtained in 81% yield.

关键词： lactonization crotocembreneic acid neocrotocembreneic acid synthesis

A Novel Access to Organostannane Compounds under Ultrasound Irradiation

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Chinese Chemical Letters 2003年第4期14卷 341-342页

作者： li Zeng PENG Tian Sheng MEI Tao ZHANG yu lin li National Laboratory of Applied Organic Chemistry&Institute of Organic Chemistry Lanzhou UniversityLanzhou 73000

A simple and efficient procedure has been developed for the synthesis of organostannane compounds by one-pot reaction of stannane halides, magnesium turnings and organic halides in the presence of 1, 2-dibromoethane u... 详细信息

关键词： Organostannane one-pot reaction ultrasound irradiation.