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醇析分级和酶法去蛋白对甜菜膳食纤维性质的影响

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华南理工大学学报（自然科学版） 2012年第5期40卷 139-144页

作者：朱思明王文婷于淑娟华南理工大学轻化工研究所广东广州510640

为揭示提取纯化方法对甜菜膳食纤维性质的影响,促进废粕高值化,探讨了废粕原料及预处理方法对果胶品质的影响,以HPLC和哈克流变仪分析了酸溶醇析法分级果胶的理化性质,并用扫描电镜研究了酶法去蛋白对不溶性膳食纤维(IDF)形貌结构的影响... 详细信息

为揭示提取纯化方法对甜菜膳食纤维性质的影响,促进废粕高值化,探讨了废粕原料及预处理方法对果胶品质的影响,以HPLC和哈克流变仪分析了酸溶醇析法分级果胶的理化性质,并用扫描电镜研究了酶法去蛋白对不溶性膳食纤维(IDF)形貌结构的影响.结果表明:3种废粕提取果胶不需稀酸或温水预处理;最佳条件下颗粒粕提取的果胶的得率和纯度之积最大;酸溶醇析法分级果胶含悬浮层和沉淀层,悬浮层果胶密度小、色泽浅、黏度高、大分子果胶比例大;提取果胶后压粕孔状骨架结构更光洁,孔内填充颗粒物消失,再经去蛋白处理后孔隙变大,IDF出现层状骨架结构.

关键词：甜菜膳食纤维分级去蛋白醇析法流变性骨架结构

Lanthanum promoting bone formation by regulating osteogenesis,osteoclastogenesis and angiogenesis

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Journal of Rare Earths 2024年第3期42卷 621-628,I0007页

作者： Dandan Zou Runlian Lin yu Han juan Jia Guoqiang Zhou Haisong Zhang Kun Ge Hebei Key Laboratory of Chronic Kidney Diseases and Bone Metabolism Affiliated Hospital of Hebei UniversityBaoding071000China Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education Key Laboratory of Chemical Biology of Hebei ProvinceCollege of Chemistry and Environmental ScienceHebei UniversityBaoding071002China

With lanthanum(La) in agriculture, medicine, and the chemical industry, La shows accumulation in the body, especially in the bone, because of its similar structure to calcium. Moreover, La has a direct role in bone formation regulating osteoblasts and osteoclasts. Nevertheless, bone formation is complex under the regulation of osteogenesis, osteoclastogenesis, and angiogenesis in the bone microenvironment. It is difficult to comprehensively understand the regulation of bone homeostasis from a single kind of ***, some bone microenvironment-related cells and mouse calvaria culture models were used to study the regulatory effect of La-based compound-lanthanum nitrate(La(NO_(3))_(3)) on bone ***(NO_(3))_(3) has good biological safety, and the osteogenic differentiation is significantly increased under La(NO_(3))_(3) treatment for bone marrow mesenchymal stem cells(BMMSC). In contrast, the differentiation,maturation, and bone erosion ability of osteoclasts are significantly decreased. Meanwhile, the angiogenesis ability of human umbilical vein endothelial cells(HUVEC) is significantly promoted when treated with La(NO_(3))_(3). Furthermore, bone metabolism and angiogenesis are improved under La(NO_(3))_(3) treatment in the calvaria ex vivo culture model and BMMSC-HUVEC co-culture system. These results suggest that La has the beneficial effect of promoting bone metabolism and improving bone formation in the bone microenvironment.

关键词： Lanthanum Bone microenvironment Osteogenic differentiation Angiogenesis Rare earths

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基于混沌神经网络的盲检测改进新算法

物理学报 2014年第6期63卷 117-123页

作者：于舒娟宦如松张昀冯迪南京邮电大学电子科学与工程学院南京210003 中国移动通信集团江苏有限公司苏州分公司苏州215002

针对Hopfield神经网络的多起点问题,提出了一种新的基于混沌神经网络的盲信号检测算法,实现了二进制移相键控信号盲检测.据此进一步提出双sigmoid混沌神经网络模型,构造了新的能量函数,且证明了该模型的稳定性,并对网络参数进行配置.仿... 详细信息

针对Hopfield神经网络的多起点问题,提出了一种新的基于混沌神经网络的盲信号检测算法,实现了二进制移相键控信号盲检测.据此进一步提出双sigmoid混沌神经网络模型,构造了新的能量函数,且证明了该模型的稳定性,并对网络参数进行配置.仿真实验表明:混沌神经网络能够避免局部极小点且具备较强的抗噪性能,双sigmoid混沌神经网络则继承了其所有的优点,且其收敛速度更快,仅需更短的接收数据即可到达全局真实平衡点,从而降低了算法的计算复杂度,减少了运行时间.

关键词：混沌神经网络双sigmoid混沌神经网络盲检测

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采用CUSOC工艺精制凝胶多糖

华南理工大学学报（自然科学版） 2007年第4期35卷 46-51页

作者：赵振刚陈山卢家炯于淑娟华南理工大学轻工食品工程学院广东广州510640 广西大学糖业工程技术研究中心广西南宁530004

为得到高纯度的凝胶多糖,采用分级膜(30 ku,100 ku)超滤同时耦合溶析结晶的方法——循环超滤-溶析结晶(CUSOC)法对凝胶多糖粗品进行了分级纯化,制备出了纯度分别达96.5%和93.3%的凝胶多糖产品,并对100 ku膜截留液所精制的多糖(CUD3)的... 详细信息

为得到高纯度的凝胶多糖,采用分级膜(30 ku,100 ku)超滤同时耦合溶析结晶的方法——循环超滤-溶析结晶(CUSOC)法对凝胶多糖粗品进行了分级纯化,制备出了纯度分别达96.5%和93.3%的凝胶多糖产品,并对100 ku膜截留液所精制的多糖(CUD3)的组成进行了初步分析.结果表明,整个工艺过程的多糖截留率都在95%以上,多糖聚合物总收率约为93.10%.紫外光谱和纸层析鉴定表明,CUSOC方法能有效除去大部分小分子色素及核酸类杂质,凝胶多糖的水解物为单一葡萄糖.红外光谱分析表明,该多糖属β-D-糖苷键构型.

关键词：凝胶多糖分离纯化超滤溶析结晶过程耦合

Optimal timing of invasive intervention for high-risk non-ST-segment-elevation myocardial infarction patients

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Journal of Geriatric Cardiology 2024年第8期21卷 807-815页

作者： juan-juan ZHENG yue-Qiao SI Tian-Yang XIA Bing-Jun LU Chun-yu ZENG Wei-Eric WANG Department of Geriatrics Southwest HospitalThird Military Medical UniversityChongqingChina Department of Cardiology Daping HospitalThird Military Medical UniversityChongqingChina

OBJECTIVE To compare the immediate,early,and delayed percutaneous coronary intervention(PCI)strategies in non-ST-segment-elevation myocardial infarction(NSTEMI)patients with *** Medical records of patients treated at the Daping Hospital,Third Military Medical University,Chongqing,China between 2011 and 2021 were retrospectively *** patients with complete available information were *** patients assigned into three groups based on the timing of PCI including immediate(<2 h),early(2–24 h)and delayed(≥24 h)*** Cox hazards regression and simpler nonlinear models were *** A total of 657 patients were included in the *** median follow-up length was 3.29(interquartile range:1.45–4.85)*** PCI strategy improved the major adverse cardiac event(MACE)outcome compared to the immediate or delayed PCI *** PCI,diabetes mellitus,and left main or/and left anterior descending or/and left circumflex stenosis or/and right coronary artery≥99%were predictors for MACE *** optimal timing range for PCI to reduce MACE risk is 3–14 h *** high-risk NSTEMI patients,early PCI reduced primary clinical outcomes compared to immediate or delayed PCI,and the optimal timing range was 3–14 h *** PCI was superior for NSTEMI with chronic kidney *** Delayed invasive strategy was helpful to reduce the incidence of MACE for high-risk NSTEMI with chronic kidney *** immediate PCI strategy might increase the rate of MACE.

关键词： patients infarction Chongqing

Feasibility study of the photonuclear reaction cross section of medical radioisotopes using a laser Compton scattering gamma source

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Nuclear Science and Techniques 2024年第9期35卷 168-177页

作者： yu-Ning Gu Wei-juan Zhao Xi-Guang Cao yu-Xuan Yang Ting-Kai Ma Zheng-Li Liao Fei-Long Xu yu-Gang Ma School of Physics and Microeletronics Zhengzhou UniversityZhengzhou 450001China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China School of Nuclear Science and Technology University of South ChinaHengyang 421001China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Shanghai Research Center for Theoretical Nuclear Physics NSFC and Fudan UniversityShanghai 200438China

In recent years,the gap between the supply and demand of medical radioisotopes has increased,necessitating new methods for producing medical *** reactions based on gamma sources have unique advantages in terms of producing high specific activity and innovative medical ***,the lack of experimental data on reaction cross sections for photonuclear reactions of medical radioisotopes of interest has severely limited the development and production of photonuclear transmutation medical *** this study,the entire process of the generation,decay,and measurement of medical radioisotopes was simulated using online gamma activation and offline gamma measurements combined with a shielding gamma-ray *** on a quasi-monochromatic gamma beam from the Shanghai Laser Electron Gamma Source(SLEGS),the feasibility of this measurement of production cross section for surveyed medi-cal radioisotopes was simulated,and specific solutions for measuring medical radioisotopes with ultra-low production cross sections were *** feasibility of this method for high-precision measurements of the reaction cross section of medical radioisotopes was demonstrated.

关键词： Medical radioisotope Photonuclear reaction GEANT4 Shanghai Laser Electron Gamma Source(SLEGS) Low-background gamma-ray spectrometer

Early postoperative complications after transverse colostomy closure,a retrospective study

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 807-815页

作者： Fei Liu Xiao-juan Luo Zi-Wei Li Xiao-yu Liu Xu-Rui Liu Quan Lv Xin-Peng shu Wei Zhang Dong Peng Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Endoscopy Center The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400012China

BACKGROUND Ostomy is a common surgery usually performed to protect patients from clinical symptoms caused by distal anastomotic leakage after colorectal cancer(CRC)surgery and perforation or to relieve intestinal *** To analyze the complications after transverse colostomy *** Patients who underwent transverse colostomy closure from Jan 2015 to Jan 2022 were retrospectively enrolled in a single clinical *** differences between the complication group and the no complication group were *** regression analyses were conducted to find independent factors for overall complications or incision *** A total of 102 patients who underwent transverse colostomy closure were enrolled in the current ***(68.6%)patients underwent transverse colostomy because of CRC related *** complications occurred in 30(29.4%)patients and the most frequent complication occurring after transverse colostomy closure was incision infection(46.7%).The complication group had longer hospital stays(P<0.01).However,no potential risk factors were identified for overall complications and incision *** The most frequent complication occurring after transverse colostomy closure surgery in our center was incision *** operation time,interval from transverse colostomy to reversal,and method of anastomosis might have no impact on the postoperative *** should pay more attention to aseptic techniques.

关键词： Transverse colostomy closure Surgery Complications A single clinical centre Risk factors

Near-zero-adhesion-enabled intact wafer-scale resist-transfer printing for high-fidelity nanofabrication on arbitrary substrates

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International Journal of Extreme Manufacturing 2024年第1期6卷 313-326页

作者： Zhiwen shu Bo Feng Peng Liu Lei Chen Huikang Liang Yiqin Chen Jianwu yu Huigao Duan College of Mechanical and Vehicle Engineering National Engineering Research Centre for High Efficiency GrindingHunan UniversityChangsha 410082People’s Republic of China Greater Bay Area Institute for Innovation Hunan UniversityGuangzhou 511300People’s Republic of China School of Mechanical Engineering Hunan University of Science and TechnologyXiangtan 411201People’s Republic of China Shenzhen Research Institute Hunan UniversityShenzhen 518000People’s Republic of China

There is an urgent need for novel processes that can integrate different functional nanostructures onto specific substrates,so as to meet the fast-growing need for broad applications in nanoelectronics,nanophotonics,and fexible *** direct-lithography methods are difficult to use on fexible,nonplanar,and biocompatible ***,this fabrication is usually accomplished by nanotransfer ***,large-scale integration of multiscale nanostructures with unconventional substrates remains challenging because fabrication yields and quality are often limited by the resolution,uniformity,adhesivity,and integrity of the nanostructures formed by direct ***,we proposed a resist-based transfer strategy enabled by near-zero adhesion,which was achieved by molecular modification to attain a critical surface energy *** approach enabled the intact transfer of wafer-scale,ultrathin-resist nanofilms onto arbitrary substrates with mitigated cracking and wrinkling,thereby facilitating the in situ fabrication of nanostructures for functional *** this approach,fabrication of three-dimensional-stacked multilayer structures with enhanced functionalities,nanoplasmonic structures with~10 nm resolution,and MoS2-based devices with excellent performance was demonstrated on specific *** results collectively demonstrated the high stability,reliability,and throughput of our strategy for optical and electronic device applications.

关键词： resist-based transfer printing near-zero adhesion critical surface energy wafer-scale nanofabrication in situ fabrication optoelectronic devices

Changes in microstructure and properties of weld heat-affected zone of high-strength low-alloy steel

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Journal of Iron and Steel Research International 2024年第8期31卷 2041-2052页

作者： shu-jun Jia Qi-lin Ma yu Hou Ba Li He-song Zhang Qing-you Liu Central Iron and Steel Research Institute Co. Ltd.Beijing 100081China Collaborative Innovation Center for Steel Commonality University of Science and Technology BeijingBeijing 100083China Construction Project Management Branch of China National Petroleum Pipeline Network Group Co. Ltd.Langfang 065000HebeiChina

The evolution of the microstructure and toughness of APL5L X80 pipeline steel after thermal welding simulation was investigated by X-ray diffraction,electron backscatter diffraction,and transmission electron *** results indicated that primary heat-affected zones can be divided into weld,coarse-grained,fine-grained,intercritical,and sub-critical *** microstructure of the weld zone is mainly composed of bainitic ferrite and a small amount of granular bainite;however,the original austenite grains are distributed in the columnar *** structure of the coarse-grained zone is similar to that of the weld zone,but the original austenite grains are *** contrast,the microstructure in the fine-grained zone is dominated by fine granular bainite,and the effective grain size is only 8.15μm,thus providing the highest toughness in the entire heat-affected *** intercritical and subcritical zones were brittle valley regions,and the microstructure was dominated by granular ***,the martensite-austenite(M/A)constituents are present in island chains along the grain boundaries,and the coarse size of the M/A constituents seriously reduces the *** results of the crack propagation analyzes revealed that high-angle grain boundaries can significantly slow down crack growth and change the crack direction,thereby increasing the material *** impact toughness of the low-temperature tempering zone was equivalent to that of the columnar grain zone,and the impact toughness was between those of the critical and fine-grained zones.

关键词： Welding thermal simulation Impact toughness Crack propagation Martensite-austenite constituent High-strength low-alloy steel weld Heat-affected zone