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具有重频特性系统的动力响应分析

计算力学学报 2013年第2期30卷 198-203,230页

作者：俞瑞芳周锡元袁美巧中国地震局地球物理研究所北京100081 北京工业大学结构抗震与诊治北京市重点试验室北京100213 重庆市地震工程研究所重庆401147

一般有阻尼线性系统出现重特征值时,基于振型正交性的复振型分解法将不再适用。本文综合运用高等数学、线性代数和复变函数理论,对具有重频特性的一般有阻尼线性多自由度系统给出了系统动力响应在时域中的计算方法。该方法充分利用复振... 详细信息

一般有阻尼线性系统出现重特征值时,基于振型正交性的复振型分解法将不再适用。本文综合运用高等数学、线性代数和复变函数理论,对具有重频特性的一般有阻尼线性多自由度系统给出了系统动力响应在时域中的计算方法。该方法充分利用复振型分解法和留数矩阵解耦法的优点,不仅概念清晰,而且易于理解和掌握,适合于大型复杂系统的动力响应分析。此外,本文给出了双自由度体系产生重特征值的条件,对典型实例进行了地震响应分析,并通过与Newmark-β法计算结果的对比,论证了文中所给计算公式的正确性。本文提出的分析方法具有普适性,对线性结构、机电和控制系统也都是适用的。

关键词：阻尼系统重特征值传递函数留数矩阵振型分解法

空间相关多点地震位移输入峰值控制对结构非线性响应的影响

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振动工程学报 2021年第6期34卷 1240-1249页

作者：陈科旭俞瑞芳孙平宽中国地震局地球物理研究所北京100081 中国公路工程咨询集团有限公司北京100089

在空间相关多点地震动人工拟合中,一般控制大跨结构不同支撑点处的地震加速度反应谱及加速度峰值相同,而相应于不同支撑点处位移时程的峰值则是不同的。为了研究地震动特性及不同的位移控制条件对结构响应的影响,引入两种不同的包线函... 详细信息

在空间相关多点地震动人工拟合中,一般控制大跨结构不同支撑点处的地震加速度反应谱及加速度峰值相同,而相应于不同支撑点处位移时程的峰值则是不同的。为了研究地震动特性及不同的位移控制条件对结构响应的影响,引入两种不同的包线函数分别模拟地震动强度或频率非平稳特性,并且按照控制不同支撑点处时程的加速度峰值或位移峰值相同,拟合了6组空间相关多点地震动;采用多点地震动加速度/位移输入模式,对三跨连续梁桥进行了非线性响应分析。结果表明:控制地震位移时程的峰值对结构的内力和位移响应有较大的影响,位移峰值越大,结构进入的非线性程度越深,得到的结构响应越大,且与位移时程的形状无明显相关性;以加速度反应谱和加速度峰值为目标的地震动拟合中,各支撑点处位移时程的峰值离散性比较大,为了保证结构的安全,空间相关多点地震动拟合中应控制位移峰值的最小取值;地震加速度时程的频率非平稳特性对桥梁位移和桥墩扭矩影响较大,如果仅考虑地震动强度非平稳特性,则存在低估结构响应的风险。因此,大跨结构抗震分析中应合理刻画地震动时间空间耦合特性、非平稳特性及位移输入的最小峰值,充分估计结构的非线性响应,以保证结构抗震设计的安全性。

关键词：地震动多点输入大尺度结构地震动位移峰值结构非线性响应

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Orlicz空间内的Müntz有理逼近

内蒙古师范大学学报（自然科学汉文版） 2016年第2期45卷 174-177页

作者：于蕊芳吴嘎日迪内蒙古师范大学数学科学学院内蒙古呼和浩特010022

利用Bak算子,给出光滑函数的Müntz有理逼近的速度估计,并进一步考虑了变化后的Müntz系统中,有理函数对光滑函数的逼近,其逼近速度优于通常的Müntz有理函数的逼近.

关键词： Bak算子 Orlicz空间 Müntz有理逼近

Advances in the Development of Gradient Scaffolds Made of Nano‑Micromaterials for Musculoskeletal Tissue Regeneration

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Nano-Micro Letters 2025年第3期17卷 455-500页

作者： Lei fang Xiaoqi Lin ruian Xu Lu Liu yu Zhang Feng Tian Jiao Jiao Li Jiajia Xue Beijing Laboratory of Biomedical Materials Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China School of Biomedical Engineering Faculty of Engineering and ITUniversity of Technology SydneySydneyNSW 2007Australia

The intricate hierarchical structure of musculoskeletal tissues,including bone and interface tissues,necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered *** has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic *** on the anatomical characteristics of bone and interfacial tissues,this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues,specifically focusing on methods used to construct compositional and structural gradients within the *** latest applications of gradient scaffolds for the regeneration of bone,osteochondral,and tendon-to-bone interfaces are ***,the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed,as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.

关键词： Gradient scaffolds Musculoskeletal tissues Advanced manufacturing Biomaterials Tissue regeneration

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表征近断层地震动永久位移的基线校正方法

振动工程学报 2024年第12期37卷 2012-2020页

作者：陈科旭俞瑞芳徐建荣中国地震局地球物理研究所北京100081 中国电建集团华东勘测设计研究院有限公司浙江杭州311122

在对近断层原始地震加速度记录的处理中,如何保留真实的地面永久位移信息,是目前地震加速度记录基线校正中需要解决的关键问题。本文在对现有近断层地震加速度基线校正方法的有效性及适用范围分析和讨论的基础上,引入平滑斜坡位移函数模... 详细信息

在对近断层原始地震加速度记录的处理中,如何保留真实的地面永久位移信息,是目前地震加速度记录基线校正中需要解决的关键问题。本文在对现有近断层地震加速度基线校正方法的有效性及适用范围分析和讨论的基础上,引入平滑斜坡位移函数模型,建立了能够合理表征近断层地震动永久位移的一种基线校正方法,并通过典型近断层加速度记录的基线处理对该方法进行了校验。结果表明,本文建立的方法改善了位移函数模型与位移时程之间的拟合精度,能减少主观参数选择对基线校正结果的影响,且校正后的地面永久位移与GPS同震位移吻合度较高。本文建立的地震动基线校正方法不仅能够自动处理近断层地震动的基线漂移,且能合理表征由于滑冲效应而产生的地面永久位移。

关键词：近断层地震动基线校正地面永久位移 GPS同震位移

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Preparation of Modified Composite Nanofiltration Membrane Synergistically Using Carboxylic Multi- walled Carbon Nanotube and β-cyclodextrin

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 232-239页

作者： LIU Peng MAO Junpeng fang Yanfeng yu yunwu CHEN Changxiu TANG Ning WAN Ye GU Yaxin LIU yunxue WANG Lihua School of Materials Science and Engineering Shenyang Jianzhu UniversityShenyang 110168China

A new modified blend ultrafiltration(UF)membrane with good hydrophilicity,high porosity and excellent anti-fouling performance was developed by using carboxylic multi-walled carbon nanotube(CMWCNT)as casting solution ***,a composite nanofiltration(NF)membrane with large water flux and good retention rate was fabricated by using the PVDF/CMWCNT blend UF membrane as the substrate,and polyvinyl alcohol(PVA),β-cyclodextrin(β-CD)and polyethylenimine(PEI)as the coating *** results show that with the appropriate addition of CMWCNT in the casting solution,the surface roughness,porosity and recovery rate of the PVDF/CMWCNT blend UF membrane is obviously *** water flux of blend UF membrane is significantly improved when the CMWCNT content increases from 0 wt%to 0.2 wt%.The water flux of blend UF membrane with 0.2 wt%CMWCNT is 162.7 L/(m^(2)·h),which is 44.3%higher than that of the pure PVDF ***β-CD content is 0.8 wt%,the retention rate of Congo red by PVDF/CMWCNT/β-CD composite NF membrane reaches 98.7%,which is 28.3%higher than that of single PVA/PEI modified *** research will provide a new idea and simple method for developing novel high-performance composite NF membranes.

关键词： CMWCNT cyclodextrin nanofiltration membrane

Direct Photolithography of WO_(x)Nanoparticles for High‑Resolution Non‑Emissive Displays

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Nano-Micro Letters 2025年第3期17卷 297-309页

作者： Chang Gu Guojian Yang Wenxuan Wang Aiyan Shi Wenjuan fang Lei Qian Xiaofei Hu Ting Zhang Chaoyu Xiang yu‑Mo Zhang Laboratory of Optoelectronic Information Technology and Devices Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201People’s Republic of China Hangzhou Bay Laboratory of Advanced Nano‑Optoelectronic Materials and Devices Qianwan Institute of CNITECHNingbo 315336People’s Republic of China Smart Materials for Architecture Research Lab Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100People’s Republic of China University of Science and Technology of China Hefei 230026People’s Republic of China State Key Lab of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012People’s Republic of China

High-resolution non-emissive displays based on electrochromic tungsten oxides(WOx)are crucial for future near-eye virtual/augmented reality interactions,given their impressive attributes such as high environmental stability,ideal outdoor readability,and low energy ***,the limited intrinsic structure of inorganic materials has presented a significant challenge in achieving precise patterning/pixelation at the micron ***,we successfully developed the direct photolithography for WOx nanoparticles based on in situ photo-induced ligand *** strategy enabled us to achieve ultra-high resolution efficiently(line width3600 cycles),as well as promising applications in electronic logos,pixelated displays,flexible electronics,*** success and advancements presented here are expected to inspire and accelerate research and development(R&D)in high-resolution non-emissive displays and other ultra-fine micro-electronics.

关键词： Electrochromic Direct photolithography WOx nanoparticles In situ photo-induced ligand exchange High-resolution displays

Dietary carbohydrate intake and risk of type 2 diabetes:a 16-year prospective cohort study

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Science China Life Sciences 2025年

作者： Lu Gan Yi Yang Bin Zhao Kai yu Kehua Guo fang fang Zhiguang Zhou Demetrius Albanes Jiaqi Huang Key Laboratory of Diabetes Immunology Ministry of Education and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University CSU-Sinocare Research Center for Nutrition and Metabolic Health Xiangya School of Public Health Central South UniversityFurong Laboratory Division of Cancer Epidemiology and Genetics National Cancer Institute NIH Department of Health and Human Services School of Computer Science and Engineering Central South University Institute of Environmental Medicine Karolinska Institute National Clinical Research Center for Metabolic Diseases Key Laboratory of Diabetes Immunology Ministry of Education and Department of Metabolism and Endocrinology The Second Xiangya Hospital of Central South University

Despite considerable research underscoring the importance of carbohydrate intake in relation to the risk of type 2 diabetes(T2D), a comprehensive assessment of this relationship is currently lacking. We aimed to examine the associations of various types and food sources of dietary carbohydrate intake with the risk of T2D, to evaluate potential effect modification by other factors, including genetic susceptibility,and to explore the potential mediators for such associations. The present study included 161,872 participants of the UK Biobank who were free of prevalent cancer, cardiovascular disease, or diabetes, and had at least one validated 24-h dietary recall assessment. Multivariableadjusted age-stratified Cox proportional hazard regression models were applied to estimate hazard ratios(HRs) and 95% confidence intervals(CI) for the associations of various types and food sources of dietary carbohydrate intake with risk of T2D. During a median follow-up of13.6 years, 4,176 incident cases of T2D were identified. In the multivariable-adjusted models, a greater intake of fiber, carbohydrates from whole grains, and carbohydrates from non-starchy vegetables was significantly associated with a lower risk of T2D(highest vs. lowest quantile, HR [95% CI]=0.70 [0.62–0.79], 0.74 [0.67–0.82], and 0.83 [0.75–0.92], respectively, all P for trend <0.005). In contrast, a higher intake of starch and carbohydrate from starchy vegetables was associated with an increased risk of T2D(highest vs. lowest quantile, HR [95%CI]=1.31 [1.16–1.48] and 1.19 [1.09–1.31], respectively, both P for trend <0.005). Replacing one serving of refined grains or starchy vegetables with an equal amount of whole grains or non-starchy vegetables was associated with 4% to 10% lower risk of T2D(all P values <0.001).The observed associations were generally similar across population subgroups, including individuals with different genetic susceptibility to T2D. Mediation analyses of the inverse association between T

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Inhibition of the NLRP3 inflammasome attenuates spiral ganglion neuron degeneration in aminoglycoside-induced hearing loss

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Neural Regeneration Research 2025年第10期20卷 3025-3039页

作者： Jia fang Zhuangzhuang Li Pengjun Wang Xiaoxu Zhang Song Mao Yini Li Dongzhen yu Xiaoyan Li Yazhi Xing Haibo Shi Shankai Yin Department of Otolaryngology Head and Neck Surgery Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineOtolaryngology Institute of Shanghai Jiao Tong UniversityShanghai Key Laboratory of Sleep Disordered BreathingShanghaiChina Department of Otorhinolaryngology-Head and Neck Surgery Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Aminoglycosides are a widely used class of antibacterials renowned for their effectiveness and broad antimicrobial ***,their use leads to irreversible hearing damage by causing apoptosis of hair cells as their direct *** addition,the hearing damage caused by aminoglycosides involves damage of spiral ganglion neurons upon *** investigate the mechanisms underlying spiral ganglion neuron degeneration induced by aminoglycosides,we used a C57BL/6J mouse model treated with *** found that the mice exhibited auditory deficits following the acute loss of outer hair *** ganglion neurons displayed hallmarks of pyroptosis and exhibited progressive degeneration over *** profiling of these neurons showed significant upregulation of genes associated with inflammation and immune response,particularly those related to the NLRP3 *** of the canonical pyroptotic pathway in spiral ganglion neurons was observed,accompanied by infiltration of macrophages and the release of proinflammatory *** intervention targeting NLRP3 using Mcc950 and genetic intervention using NLRP3 knockout ameliorated spiral ganglion neuron degeneration in the injury *** findings suggest that NLRP3 inflammasome-mediated pyroptosis plays a role in aminoglycoside-induced spiral ganglion neuron *** of this pathway may offer a potential therapeutic strategy for treating sensorineural hearing loss by reducing spiral ganglion neuron degeneration.

关键词： degeneration hearing loss macrophages Mcc950 neuroinflammation NLRP3 inflammasome ototoxicity pyroptosis sensorineural hearing loss spiral ganglion neuron