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New Algebraic Structures from Hermitian One-Matrix Model

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Acta Mathematica Sinica,English Series 2017年第9期33卷 1193-1205页

作者： Xiang Mao DING yu ping li ling Xian MENG Institute of Applied Mathematics Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190P.R.China College of Mathematics and Information Science Zhengzhou University of Light IndustryZhengzhou 450002P.R.China

Virasoro constraint is the operator algebra version of one-loop equation for a Hermitian one-matrix model, and it plays an important role in solving the model. We construct the realization of the Virasoro constraint from the Conformal Field Theory （CFT） method. From multi-loop equations of the one-matrix model, we get a more general constraint. It can be expressed in terms of the operator algebras, which is the Virasoro subalgebra with extra parameters. In this sense, we named as generalized Virasoro constraint. We enlarge this algebra with central extension, this is a new kind of algebra, and the usual Virasoro algebra is its subalgebra. And we give a bosonic realization of its subalgebra.

关键词： Matrix model Virasoro constraint conformal symmetry

Phase Transition and Micellization of Temperature Responsive Dextran-graft-poly (N-isopropylacrylamide) Polymers

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Chinese Chemical Letters 2003年第4期14卷 407-410页

作者： li Qun WANG Ke Hua TU yu ping li Jie ZHANG Department of Polymer Science and Engineering Zhejiang UniversityHangzhou 310027

Phase behavior and micellization of dextran-graft-poly (N-isopropylacrylamide) (PNIPAAm) polymers in aqueous solution are investigated in this paper using DSC and AFM methods. It is found that with the increase of grafting (G%) of the copolymers the endothermic enthalpy during the phase transition increases significantly and the transition temperature decreases slightly. The phase transition behavior of the copolymers is scanning rate dependent. Micelles are formed whenever the solution temperature is raised above the LCST of the copolymers. It is proposed that by using this thermal responsive property of the copolymers, drugs could be incorporated into the micelles without employing any organic solvent.

关键词： Dextran, graft copolymers thermosensitive LCST.

Synthesis and Crystal Structure of 5-[(1H-1,2,4-Triazol-1- yl)methyl]-4-(2,3-dimethoxybenzylideneamino)-2-2H-1,2,4-triazole-3(4H)-thione Monohydrate

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Chinese Journal of Structural Chemistry 2006年第6期25卷 673-676页

作者： XU liang-Zhong SHANG yu-Qing yu Guan-ping li Kai SI Guo-Dong College of Chemistry and Molecular Engineering Qingdao University of Science and Technology Qingdao 266042 China

The title compound 5-[（1H-1,2,4-triazol-1-yl）methyl]-4-（2,3-dimethoxy-benzylideneamino）- 2H-1,2,4-triazole-3（4H）-thione monohydrate 4 has been synthesized by the treatment of 4-amino-3-（ 1,2,4-triazol- 1-yl）- 1 H- 1,2,4-triazole-5（4H）-thione 3 with 2,3-dimethoxybenzaldehyde. It crystallizes as a monohydrate in the triclinic system, space group P1^- with a = 8.147（2）, b = 10.820（2）, c = 10.835（2）A, α= 73.770（6）, β = 84.916（7）,γ = 70.679（6）°, C14H17N7O35, Mr = 363.41, V= 865.4（2）A^3, Z= 2, Dc = 1.395 g/cm^3, F（000） = 380, μ = 0.217 mm^-1, the final R = 0.0400 and wR = 0.0975 for 3454 unique reflections. The dihedral angles made by the thione-substituted triazole ring with the other triazole ring and benzene ring are 74.92（3） and 14.81（2）°, respectively. There are some weak hydrogen bonds and C-H..π supramolecular interactions in the lattice, forming a three-dimensional network, which stabilizes the crystal structure.

关键词： 1,2,4-triazole crystal structure synthesis

Transglutaminase 2 serves as a pathogenic hub gene of KRAS mutant colon cancer based on integrated analysis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2074-2090页

作者： Wei-Bin Peng yu-ping li Yong Zeng Kai Chen First People’s Hospital of Foshan Foshan 528000Guangdong ProvinceChina Department of Radiation Oncology Cancer Hospital of Shantou University Medical CollegeShantou 515031Guangdong ProvinceChina

BACKGROUND Colon cancer is acknowledged as one of the most common malignancies worldwide,ranking third in United States regarding incidence and ***,approximately 40%of colon cancer cases harbor oncogenic KRAS mutations,resulting in the continuous activation of epidermal growth factor receptor *** To investigate the key pathogenic genes in KRAS mutant colon cancer holds considerable *** Weighted gene co-expression network analysis,in combination with additional bioinformatics analysis,were conducted to screen the key factors driving the progression of KRAS mutant colon ***,various in vitro experiments were also conducted to explore the biological function of transglutaminase 2(TGM2).RESULTS Integrated analysis demonstrated that TGM2 acted as an independent prognostic factor for progression-free *** analysis on tissue microarrays revealed that TGM2 was associated with an elevated probability of perineural invasion in patients with KRAS mutant colon ***,biological roles of the key gene TGM2 was also assessed,suggesting that the downregulation of TGM2 attenuated the proliferation,invasion,and migration of the KRAS mutant colon cancer cell *** This study underscores the potential significance of TGM2 in the progression of KRAS mutant colon *** insight not only offers a theoretical foundation for therapeutic approaches but also highlights the need for additional clinical trials and fundamental research to support our preliminary findings.

关键词： Colon cancer KRAS mutation Transglutaminase 2 Weighted gene co-expression network analysis

Drag reduction and shear resistance properties of ionomer and hydrogen bond systems based on lauryl methacrylate

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Petroleum Science 2011年第3期8卷 357-364页

作者： yu ping li Changyu Zhang Changqiao Chen Shiwei Fang Shu Sun Hui School of Chemistry and Chemical Engineering Shandong University Jinan 250061 China

Based on molecular dynamics simulation results, a lauryl methacrylate polymer with drag reduction and shear resistance properties was designed, and synthesized by emulsion polymerization using 2-vinyl pyridine and methyl methacrylate as the polar polymerization monomer. After ionization of lauryl methacrylate polymer, an ion-dipole interaction based drag reduction agent （DRA） was obtained. The existence of ion-dipole interaction was proven through characterization of the drag-reducing agent from its infrared （IR） spectrum. The pilot-scale reaction yield of the DRA under optimum conditions was investigated, and the drag reduction and shear resistance properties were measured. The results show that： l） The ion-dipole or hydrogen bonding interaction can form ladder-shaped chains, therefore the synthesized DRA has shear resistance properties; 2） The larger the molecular weight （MW） and more concentrated the distribution of MW, the better the drag reduction efficiency and the performance of the ionomer system was superior to that of the hydrogen bonding system; 3） With increasing shear frequency, the drag-reduction rates of both the DRAs decreased, and the drag reduction rate of the ionomer system decreased more slowly than of the corresponding hydrogen bonding system. From the point of view of drag reduction rate and shear resistance property, the ionomer system is more promising than the hydrogen bonding system

关键词： Molecular design ion-dipole interaction hydrogen bonding drag reduction rate shearresistance property

Invasive aspergillosis presenting as hilar masses with stenosis of bronchus: A case report

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World Journal of Clinical Cases 2019年第22期7卷 3832-3837页

作者： Shan-Shan Su Ying Zhou Han-Yan Xu ling-ping Zhou Cheng-Shui Chen yu-ping li Key Laboratory of Intervention Pulmonology of Zhejiang Province Department of Pulmonary and Critical Care Medicine The First Affiliated Hospital of Wenzhou Medical University

BACKGROUND Hilar masses with stenosis of the bronchus occur mainly due to malignant diseases,such as lung *** masses resulting from invasive aspergillosis are extremely rare and occur mostly in severely immunosuppressed *** SUMMARY In the current case report,we have documented a unique case of invasive aspergillosis presenting as a mass in the hilum and bronchial stenosis under bronchoscopy mimicking lung cancer in a 54-year-old man with diabetes *** histological analysis of bronchial membrane biopsy demonstrated fungal elements of 45°branching hyphae with positive Periodic Acid-Schiff and Grocott *** 3 mo of antifungal therapy,the symptoms,computed tomography scan and bronchoscopy manifestations all showed *** We highlight that clinicians should consider a diagnosis of invasive aspergillosis when radiological examination shows pseudotumor appearance in diabetes mellitus patients.

关键词： Invasive aspergillosis Lymph nodes Lung cancer Bronchoscopy Casereport

Impact of Soil Fumigation Practices on Soil Nematodes and Microbial Biomass

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Pedosphere 2004年第3期14卷 387-393页

作者： CAO Zhi—ping yu Yong—li CHEN Guo-Kang R.DAWSON Department of Ecology and Ecological Engineering College of Resources and Environmental ScienceChina Agricultural UniversityBeijing 100094(China).

This study was designed to understand the impact of methyl bromide (MB) (CH3Br) and its alternatives on both free-living and root-knot nematodes in the soil. A randomized complete block experiment with six treatments and 4 replicates (each replicate in a separate greenhouse) was established in Qingzhou, Shandong Province, China. In addition to MB and untreated control (CK) treatments there were four alternative soil fumigation practices including MB+virtually impermeable films (VIF), metam sodium (MS), MS +VIF and soil solarization combined with selected biological control agents (SS+BCA). Two tomato (Lycopersicum esculentum Mill.) cultivars, cv. Maofen-802 from the Xian Institute of Vegetable Science, China, and cv. AF179 Brillante from the Israeli Hazera Quality Seeds, were selected as test crops. The results indicated that Rhabditidae was the most dominant population with percentage abundance as high as 85% of the total number of identified free-living nematodes, followed by that of Cephalobidae. Methyl bromide and its alternatives except for the non-chemical SS+BCA treatment controlled the target pest, root-knot nematodes. Also, the impact of the three chemical alternatives on free-living nematode number and functional group abundance was similar to the impact associated with a typical methyl bromide application. Chemical fumigation practices, especially that with MB, significantly reduced the number of nematodes in the soil and simultaneously significantly reduced the number of nematode genera thereby reducing nematode diversity. All the four soil chemical fumigation activities decreased soil microbial biomass and had an obvious initial impact on microorganism biomass. Furthermore, both plant-parasitic and fungivore nematodes were positively correlated with soil microbial biomass.

关键词： methyl bromide microbial biomass nematode soil fumigation

Multisystem involvement Langerhans cell histiocytosis in an adult:A case report

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World Journal of Clinical Cases 2020年第20期8卷 4966-4974页

作者： Bei-Bei Wang Jun-Ru Ye yun-Lei li Yi Jin Zhong-Wei Chen Jian-Min li yu-ping li Department of Pulmonary and Critical Care Medicine The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina Pathology Department The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina Radiology Department The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

BACKGROUND Langerhans cell histiocytosis(LCH)is a rare condition wherein Langerhans cells proliferate abnormally,adversely impacting organs including lymph nodes,bones,skin,lungs,and pituitary *** LCH disease course varies widely among patients from a self-limiting condition to one that progresses rapidly and culminates in *** is uncommon for multisystem LCH to be observed in *** we describe a woman suffering from multi-system LCH *** SUMMARY A 37-year old Chinese woman was admitted to the hospital in June 2019 suffering from dyspnea that had progressed over the course of 5 *** medical history included:central diabetes insipidus(DI)that had been treated via radiotherapy,desmopressin acetate,and bromocriptine;bilateral pneumothorax with two surgeries having been performed to remove bullae;and autoimmune hepatitis that had been unsuccessfully treated using a combination of methylprednisolone and mycophenolate mofetil.A chest computed tomography(CT)scan revealed the presence of multiple pulmonary cysts of varying *** re-analyzed right pulmonary bullae samples that had been removed in 2014,performed a systematic 18 F-FDG PET/CT analysis,and convened a multidisciplinary medical team to diagnose and treat this *** a result,we were able to eventually diagnose this patient with LCH that was not associated with BRAF-V600 E *** We hope to emphasize the importance of systemic evaluation and of cooperation between multidisciplinary physicians with the goal of improving awareness and detection of this orphan disease.

关键词： Langerhans cell histiocytosis Lung Pituitary gland liver Case report

Ring-opening Polymerization ofε-Caprolactone Using Lanthanide Tris(4-tert-butylphenolate)s as a Single-component Initiator

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Chinese Chemical Letters 2003年第10期14卷 1021-1023页

作者： Cui ping yu, li Fang ZHANG, Zhi Quan SHEN Institute of Polymer Science, Zhejiang University, Hangzhou 310027 Institute of Polymer Science Zhejiang University Hangzhou 310027 China

The ring-opening polymerization of e-caprolactone (CL) initiated by novel single lanthanide tris(4-tert-butylphenolate)s [Ln(OTBP)3] is reported. Single-component La(OTBP)3 can effectively prepare polycaprolactone (PCL) with over 90% yield and viscosity average molecular weight about 60 x 10 under quite mild conditions: molar ratio of CL to initiator is 1000, 60 C, 2 h in toluene. Mechanism study indicates that the monomer inserts into the growing chain via the break of acyl-oxygen bond of CL.

关键词： Lanthanide tris(4-tert-butylphenolate)s e-caprolactone ring-opening polymerization.