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A new perspective on functional redundancy and phylogenetic niche conservatism in soil microbial communities

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Pedosphere 2020年第1期30卷 18-24页

作者： yu jia Joann K.WHALEN Department of Natural Resource Sciences Macdonald Campus of McGill UniversitySte-Anne-de-BellevueQuebec H9X 3V9(Canada)

Functional redundancy in soil microbial communities seems to contradict the notion that individual species have distinct metabolic niches in multi-species *** soil microbiota have the metabolic capacity for"basic"functions(e.g.,respiration and nitrogen and phosphorus cycling),but only a few soil microbiota participate in"rare"functions(e.g.,methanogenesis and mineralization of recalcitrant organic pollutants).The objective of this perspective paper is to use the phylogenetic niche conservatism theory as an explanation for the functional redundancy of soil *** niche conservatism is defined as the tendency for lineages to retain ancestral functional characteristics through evolutionary *** present-day soil microbiota is the result of a community assembly process that started when prokaryotes first appeared on *** billions of years,microbiota have retained a highly conserved set of core genes that control the essential redox and biogeochemical reactions for life on *** genes are passed from microbe to microbe,which contributes to functional redundancy in soil microbiota at the planetary *** assembly of microbial communities during soil formation is consistent with phylogenetic niche *** a specific soil,the heterogeneous matrix provides an infinite number of sets of diverse environmental conditions,i.e.,niches that lead to the divergence of microbial *** phylogenetic niche conservatism theory predicts that two or more microbial species diverging from the same clade will have an overlap in their niches,implying that they are functionally redundant in some of their metabolic *** endogenous genetic factors that constrain the adaptation of individuals and,thus,populations to changing environmental conditions constitute the core process of phylogenetic niche ***,the degree of functional redundancy in a particular soil is proportional to the complexity of the

关键词： basic function conceptual model core gene environmental factor genetic factor niche overlap rare function soil biodiversity

EPMDA:an efficient privacy-preserving multi-dimensional data aggregation scheme for edge computing-based IoT system

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The Journal of China Universities of Posts and Telecommunications 2021年第6期28卷 26-35页

作者： Tao yunting Kong Fanyu yu jia School of Software Shandong UniversityJinan 250101China College of Computer Science and Technology Qingdao UniversityQingdao 266071China

In order to perform multi-dimensional data aggregation operations efficiently in edge computing-based Internet of things(IoT) systems, a new efficient privacy-preserving multi-dimensional data aggregation(EPMDA) scheme is proposed in this paper. EPMDA scheme is characterized by employing the homomorphic Paillier encryption and SM9 signature algorithm. To improve the computation efficiency of the Paillier encryption operation, EPMDA scheme generates a pre-computed modular exponentiation table of each dimensional data, and the Paillier encryption operation can be implemented by using only several modular multiplications. For the multi-dimensional data, the scheme concatenates zeros between two adjacent dimensional data to avoid data overflow in the sum operation of ciphertexts. To enhance security, EPMDA scheme sets random number at the high address of the exponent. Moreover, the scheme utilizes SM9 signature scheme to guarantee device authentication and data integrity. The performance evaluation and comparison show that EPMDA scheme is more efficient than the existing multi-dimensional data aggregation schemes.

关键词： multi-dimensional data aggregation Paillier cryptosystem Internet of things(IoT) edge computing-based

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Theoretical screening of the transition metal heteronuclear dimer anchored graphdiyne for electrocatalytic nitrogen reduction

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Journal of Energy Chemistry 2021年第3期30卷 501-509页

作者： Dongwei Ma Zaiping Zeng Liangliang Liu yu jia Key Laboratory for Special Functional Materials of Ministry of Education and School of Materials Science and EngineeringHenan UniversityKaifeng 475004HenanChina International Laboratory for Quantum Functional Materials of Henan and School of Physics and EngineeringZhengzhou UniversityZhengzhou 450001HenanChina

Developing efficient electrocatalysts for nitrogen reduction reaction(NRR)is crucial to replace the both energy-intensive and environment-malignant Haber-Bosch *** using density functional theory calculations,we systematically studied the potential of the heteronuclear 3 d transition metal dimers anchored graphdiyne monolayers(FeM@and NiM@GDY,M=Ti,V,Cr,Mn,Fe,Co,Ni,and Cu)as efficient NRR *** all the studied double-atom catalysts(DACs),FeCo@and NiCo@GDY are the most promising with excellent NRR catalytic activity,high ability to suppress the competing hydrogen evolution reaction(HER),and good *** both FeCo@and NiCo@GDY,NRR prefers to the distal pathway with the calculated onset potentials of -0.44 and -0.36 V,respectively,which are comparable and even better than their homonuclear ***,FeCo@and NiCo@GDY have higher ability to suppress HER than Fe_(2)@ and Co_(2)@GDY,which may result from the modulated d state electronic structure due to the synergy effect of the heteronuclear atoms in the *** work not only suggests that FeCo@and NiCo@GDY hold great promises as efficient,low-cost,and stable DACs for NRR,but also further provides a strategy,*** the atomic metal catalysts,to improve the NRR catalytic activity and/or selectivity.

关键词： Nitrogen reduction reaction Graphdiyne Double-atom catalyst First Principles calculation

Development of hepatitis C virus vaccine using hepatitis B core antigen as immuno-carrier

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World Journal of Gastroenterology 2006年第48期12卷 7774-7778页

作者： jia-yu Chen Fan Li Medical School of Taizhou Uiversity Taizhou 318000 Zhejiang Province China Department of Pathogenobiology School of Basic Medical Sciences Jilin University Changchun 130021 Jilin Province China

AIM: To develop hepatitis C virus (HCV) vaccine using HBcAg as the immuno-carrier to express HCV T epitope and to investigate its immunogenicity in mice. METHODS: We constructed the plasmid pTrc-coreNheI using gene engineering technique, constructed the pcDNA3.1-coreNheI-GFP plasmid with GFP as the reporter gene, and transfected them into Hela cells. The expression of GFP was observed under confocal microscopy and the feasibility of using HBcAg as an immuno-carrier vaccine was studied. pTrc-core gene with a synthetic T epitope antigen gene of HCV (35-44aa) was fused and expressed in the plasmid pTrc- core-HCV (T). For the fusion of the HBcAg-T protein, sucrose, density gradient centrifugation was used, and its molecular weight and purity were analyzed by SDS- PAGE. Then balb/c mice were immunized by the plasmid with the HBcAg (expressed by pTrc-core) protein as control. The tumor regression potential was investigated in mice and evaluated at appropriate time. After three times of immunization, the peripheral blood and spleen of vaccinated mice were collected. HBcAb was detected by ELISA, and nonspecific T lymphocyte proliferation and response of splenocytes were respectively examined by MTT assay. T cell subset of blood and spleen were detected by FACS. RESULTS: GFP was successfully expressed. Tumor regression trial showed that no tumor formation was found in the group receiving immunization, while tumor xenograft progression was not changed in the control group. Strong nonspecific lymphocyte proliferation response was induced. FACS also showed that the ratio of CD8+ T cells in the experimental group was higher than the controls, but the serum HBcAb in experimental group was similar to the control. CONCLUSION: HBcAg can be used as an immuno-carrier of vaccine, the fusion of HBcAg-T protein could induce stronger cellular immune responses and it might be a candidate for therapeutic vaccines specific for HCV.

关键词： Hepatitis C virus Therapeutic vaccine T epitope Cellular immune responses

Two-Dimensional Terahertz Time-Domain Spectroscopy and Its Applications

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Journal of Electronic Science and Technology 2015年第1期13卷 6-13页

作者： jia-yu Zhao Wei-Wei Liu Key Laboratory of Optical Information Science and Technology of Ministry of Education Nankai University

In this work, we review the developing progress of two-dimensional terahertz time-domain spectroscopy（THz-TDS） and its diverse applications, including analyzing the polarization of THz radiation from a laser-induced plasma source and studying the corresponding physical mechanism, and characterizing the optical properties of crystals, etc.

关键词： Application laser-induced plasma optical property physical mechanism polarization two-dimensional terahertz time-domain spectros

Influences of Structure Disorder and Temperature on Properties of Proton Conductivity in Hydrogen-Bond Molecular Systems

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Communications in Theoretical Physics 2007年第2期47卷 235-243页

作者： PANG Xiao-Feng yu jia-Feng Institute of Life Science and Technology University of Electronic Science and Technology Chengdu 610054 China International Centre for Materials Physics the Chinese Academy of Sciences Shenyang 110015 China

The dynamic properties of proton conductivity along hydrogen-bonded molecular systems, for example, ice crystal, with structure disorder or damping and finite temperatures exposed in an externally applied electric-field have been numerically studied by Runge-Kutta way in our soliton model. The results obtained show that the proton-soliton is very robust against the structure disorder including the fluctuation of the force constant and disorder in the sequence of masses and thermal perturbation and damping of medium, the velocity of its conductivity increases with increasing of the externally applied electric-field and decreasing of the damping coefficient of medium, but the proton-soliton disperses for quite great fluctuation of the ＂force constant and damping coefficient. In the numerical simulation we find that the proton-soliton in our model is thermally stable in a large region of temperature of T ≤ 273 K under influences of damping and externally applied electric-field in ice crvstal. This shows that our model is available and appropriate to ice.

关键词： proton conductivity structure disorder temperature hydrogen bonded system

Successful remimazolam sedation-epidural block in an older patient with severe chronic obstructive pulmonary disease:A case report

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World Journal of Clinical Cases 2023年第14期11卷 3330-3339页

作者： jia-jia yu Huan-Shuang Pei yu Meng Department of Anesthesiology The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Chronic obstructive pulmonary disease(COPD)is associated with high morbidity and mortality rates *** patients have a degenerative cardiopulmonary function,weak compensatory capacity,and poor surgical ***,the mode of anesthesia must be *** is a new ultrashort-acting benzodiazepine with a rapid onset of action,rapid metabolism,and mild effects on pulmonary *** sedation combined with an epidural block has not been reported in hypertensive older adults with severe COPD and inguinal mass *** SUMMARY We report the case of a 73-year-old man with hypertension and severe COPD,who underwent resection of an enlarged inguinal mass that he had noticed more than 7 mo before *** patient presented with a“right inguinal mass”and was recommended to undergo an enlarged inguinal mass *** was relatively challenging,due to the large mass(13 cm×8 cm×7 cm),hard texture,and poor *** the advanced age of the patient,gradeⅢhypertension,and severe COPD,we administered remimazolam combined with an epidural block for anesthesia to ensure perioperative safety and careful *** anesthetic effect was precise;the procedure was performed smoothly without any complications,and the patient was successfully ***,anesthetic management in such cases has not yet been reported by previous *** Remimazolam sedation combined with an epidural block is safe and effective in older patients with hypertension and severe COPD.

关键词： Remimazolam Older adult Chronic obstructive pulmonary disease Epidural block Case report

Hyperlactemia associated with secondary hepatocellular carcinoma resection in relation to circulation stability and quality of recovery:A case report

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World Journal of Clinical Cases 2023年第8期11卷 1869-1877页

作者： yu Meng Huan-Shuang Pei jia-jia yu Department of Anesthesiology The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Intraoperative hyperlactatemia often affects circulatory stability,vital organ function,and postoperative recovery,poses a serious prognostic risk,and requires considerable attention from ***,we describe a case of hyperlactatemia during the postoperative resection of liver metastases after chemotherapy for sigmoid colon *** did not affect the patient's circulatory stability or quality of awakening,which is rarely reported in clinical *** present our management experience with the aim of providing a reference for future studies and clinical *** SUMMARY A 70-year-old female patient was diagnosed with postoperative liver metastasis following chemotherapy for sigmoid colon *** right hemicolectomy and cholecystectomy under general anesthesia were *** disorders,primarily hyperlactatemia,often occur *** treatment,other indices quickly returned to normal,lactate levels decreased slowly,and hyperlactatemia persisted during the awakening ***,this did not affect the patient's circulatory stability or awakening *** condition has rarely been clinically ***,we report our management experience in order to guide clinical practice in this *** did not affect circulatory stability or the quality of *** considered that active intraoperative rehydration avoided serious harm to the organism caused by hyperlactatemia due to insufficient tissue perfusion,while hyperlactatemia caused by decreased lactate clearance due to impaired liver function associated with surgical resection had a mild effect on the function of important *** Active intraoperative rehydration avoided serious harm to the organism caused by *** body temperature protection could improve lactate circulation.

关键词： Circulation Hyperlactatemia Laparoscopy Quality of awakening Secondary hepatocellular carcinoma Case report

First principle study on the possibilities of magnetism in one-dimensional In and Tl atomic wires with the full-potential linearized augmented plane wave method

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Acta Metallurgica Sinica(English Letters) 2009年第2期22卷 117-122页

作者： Zhili ZHU Jinhua GU yu jia Xing HU School of Physical Engineering and Material Physics Laboratory Zheng Zhou University Zhengzhou 450052 China

Using ab initio total energy calculations with the full-potential linearized augmented plane wave method, the possibilities of magnetism in one-dimensional In and Tl wires were explored and their properties as the function of geometric structures were studied. The results suggest that the linear In and Tl wires show magnetization at the equilibrium bond distance with magnetic moments of 0.71 and 0.67 μB/atom, respectively. Allowing ions to relax, the wires were deformed as zigzag structures, but no dimerization occurs. The zigzag wires also exhibit spontaneous magnetization, although the magnetic moments are lower than those of straight wires.

关键词： Magnetism Atomic wire First-principle-study