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Factors associated with mortality in congenital malformations of the gastrointestinal tract in a tertiary center in Senegal

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World Journal of Pediatric Surgery 2023年第1期6卷 24-29页

作者： Tshibwid A Zeng Papa Alassane Mbaye Doudou Gueye Ndèye Fatou Seck Ibrahima Bocar Wellé Rosalie Niang youssouph diedhiou Mbaye Fall Ndèye Aby Ndoye Aloïse Sagna Oumar Ndour Gabriel Ngom Department of Pediatric Surgery Albert Royer National Children’s Hospital CenterUniversitéCheikh Anta Diop Facultéde Medecine Pharmacie d'Odonto-StomatologieDakarSenegal Department of Pediatric Surgery Aristide Le Dantec University Teaching HospitalUniversitéCheikh Anta Diop Facultéde Medecine Pharmacie d'Odonto-StomatologieDakarSenegal

Objective Patients with congenital malformations(CMs)of the gastrointestinal tract(GIT)have a very high ***,the literature on the factors associated with mortality in these patients is scarce in sub-Saharan *** aim of this study is to identify independent risk factors for mortality in patients with CMs of the GIT at our pediatric surgical *** We conducted a retrospective analysis of cases with CMs of the GIT managed at a tertiary center from 2018 to *** were subdivided into two groups based on the outcomes,and variables with a significant difference were analyzed by logistic *** Our review included 226 patients,63 of whom died(27.88%).Patient age ranged from 0 to 15 *** into account statistical significance,mortality was more frequent in neonates than in older patients(57.30%vs 6.15%),in patients coming out of the Dakar area than in those from the Dakar area(43.75%vs 19.18%),in patients with abnormal prenatal ultrasound than in those with normal ultrasound(100%vs 26.67%),in premature children than in those born at term(78.57%vs 21.87%),in patients with an additional malformation than in those with an isolated malformation(69.23%vs 25.35%),and in those with intestinal,esophageal,duodenal and colonic atresia than in those with other diagnoses(100%,89%,56.25%and 50%,respectively).Referred patients died more than those who changed hospitals or came from home(55.29%vs 25%and 9.09%,respectively).On multivariable logistic regression,two independent factors of mortality were identified:presence of associated malformation[odds ratio(OR)=13.299;95%Confidence interval(CI)1.370 to 129.137]and diagnosis of esophageal atresia(OR=46.529;95%CI 5.828 to 371.425).Conclusion The presence of an associated malformation or diagnosis of esophageal atresia increases mortality in patients with CMs of the GIT in our environment.

关键词： mortality diagnosis congenital

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Management and Outcome of Ureteropelvic Junction Obstruction in Senegalese Children

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Open Journal of Urology 2022年第11期12卷 549-555页

作者： Ibrahima Bocar Wellé Ndeye Aby Ndoye Papa Alassane Mbaye Doudou Gueye Ndeye Fatou Seck Faty Balla Lo Lissoune Cissé Anderson Safari Kibanja Florent Tshibwid A. Zeng youssouph diedhiou Aloï se Sagna Oumar Ndour Gabriel Ngom Department of Pediatric Surgery Albert Royer National Children’s Hospital Centre Université Cheikh Anta Diop Dakar Senegal Department of Pediatric Surgery Aristide Le Dantec University Teaching Hospital Université Cheikh Anta Diop Dakar Senegal

Introduction: The ureteropelvic junction obstruction is a rare congenital malformation of the upper urinary tract. We report its management and outcome at Senegal’s main pediatric surgical department. Patients and Methods: We conducted a descriptive review of all patients managed in our pediatric surgical department at Albert Royer National Children’s Hospital Centre from January 1st, 2013 to December 31st, 2017. Results: Thirty patients were included in our study. The mean age was three years. Males were more affected (sex ratio of 2.75). The prenatal diagnosis was made in 23% of cases using prenatal ultrasonography. An abdominal mass was the circumstance of discovery in 36% of cases, and lumbar contact and renal sloshing were found in 66% of cases. There was no renal function impairment in 93% of cases. Urinary tract infection occurred in 50% of cases. Ultrasonography (100%) and urinary computed tomography (56%) were used to diagnose. A temporary nephrostomy was performed in 23% of cases, and as definitive treatment, an open Anderson-Hynes procedure was performed in 96% as a nephrectomy was made in a patient. Early postoperative complications were encountered in 56% of cases: urinary tract infection (36%), surgical site infection and anastomotic stenosis (6% both), and urinoma and textiloma (both in 3%). A patient died from sepsis. After a mean follow-up of 12 months, no additional complication was reported. Conclusion: Ureteropelvic junction obstruction was frequently diagnosed late, and its management carried unneglectable morbidity in our environment. A laparoscopic approach would be a solution to improve its outcome.

关键词： Ureteropelvic Junction Obstruction Management Outcome Children Senegal

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Perception of the Mechanization of Rice Cultivation and Its Effects on the Soil in the Senegal River Valley

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Agricultural Sciences 2024年第6期15卷 704-718页

作者： Cheick Atab Mane Siré diedhiou Arfang Ousmane Kémo Goudiaby Mohamed Sall Guillaume Gillet Machinery and Renewable Energy Department University of Sine Saloum El Hadji Ibrahima NIASS Kaolack Senegal Agroforestry Department Assane Seck University Ziguinchor Senegal Department of Agronomy Vegetable Production University of Sine Saloum El Hadji Ibrahima NIASS Kaolack Senegal National Training School for Agricultural Education Toulouse France

In Senegal, particularly in the Senegal River valley, agricultural mechanization remains limited, mainly due to a lack of agricultural equipment, a lack of expertise in agricultural machinery and an apprehension of the consequences on soil quality. To better understand agricultural mechanization of rice cultivation, this survey study has been carried out in the Senegal river valley. Precisely, this work aimed to characterize farm machinery and its effects on soil and rice cultivation. A questionnaire was administered to 304 out of 1270 farmers, spread over 8 rice-growing areas, 4 of which are located in the Podor department, three in Dagana and one in Saint-Louis. The results showed that 99.3% of farmers used motorized equipment, with 95.7% using tractor and 3.6% a power tiller. Offset tillage, which is a shallow cultivation practice carried out to break up hard soil without turning it over, was most widespread among growers (95.4%). 78.3% of the valley’s farmers felt that the machinery used to carry out tillage operations was inefficient. According to the farmers, the main constraints on the use of agricultural machinery in the valley were: the upkeep and maintenance of equipment (57%), the lack of expertise in mechanization (31%), and issues adapting machinery to local conditions (12%). Those constraints have contributed to a drop in yields in recent years, the spread of weeds on cultivated plots and the gradual degradation of the soil in the area according to 78% of farmers.

关键词： Agricultural Mechanization Characterization Constraints Soil Rice

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Neuroanatomical Basis of Postoperative Pain and Assessment of Its Management in a Series of Patients Undergoing Caesarean Sections

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Pain Studies and Treatment 2024年第2期12卷 21-32页

作者： Moustapha diedhiou Philippe Manyacka Ma Nyemb Ndiamé Sarr Aissatou Sarr Ousmane Thiam Mohamed Lamine Fall Health Sciences Training and Research Unit Gaston Berger Saint Louis University Saint Louis Senegal Intensive Care Unit Saint Louis Regional Hospital Saint Louis Senegal

Introduction: In recent decades, the cost of postoperative pain has been the subject of many studies based on protocols developed by scientific societies for its assessment and optimization. At the Regional Hospital of Saint-Louis (Senegal), several protocols have been developed for pain management, but no study has focused on the assessment of postoperative pain management specifically. We therefore initiated this work, the objectives of which were to remind the neuroanatomical and neurophysiological bases of postoperative pain, and to analyze the assessment and management of this pain in patients who have undergone a caesarean section. Materials and methods: This was a prospective and descriptive study, which took place in the gynecology-obstetrics department, over a period from January 2019 to July 2020. All patients who gave birth by cesarean section were included. The data was collected from a survey sheet written for this purpose. For each of the patients, the information was taken every day throughout the duration of postoperative hospitalization. Results: It appears from our work that after a cesarean section, the pain felt evolves on the first postoperative days with a peak during the second day. As in the data reported in the literature, there does not seem to be a difference in terms of pain intensity and analgesia dosage between scheduled and emergency caesarean sections. However, young age and female gender—for other types of surgeries—are risk factors associated with high postoperative pain scores. This trend is probably related to the low pain experience of tested patients. Our initial hypothesis was that acute post-operative pain after caesarean sections could be linked to defects in the perception and processing of pain by caregivers. Indeed, we have shown that awareness-raising, information, and training actions have made it possible to significantly improve the management of pain after a cesarean section. Conclusion: After a cesarean section the p

关键词： Postoperative Pain Neuroanatomical Bases Assessment Cesarean Section

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Influence of Continental Atmospheric Forcing on the Decadal Variability of the West African Monsoon

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Atmospheric and Climate Sciences 2024年第1期14卷 1-28页

作者： Adjoua Moïse Landry Famien Sandrine Djakouré Bi Tra Jean Claude Youan Serge Janicot Abé Delfin Ochou Arona diedhiou Département des Sciences et Techniques Université Alassane Ouattara de Bouaké Bouaké C&#244te d’Ivoire LASMES-UFR SSMT Université Félix Houphou&#235t Boigny d’Abidjan Abidjan C&#244te d’Ivoire LSS-UFR SSMT Université Félix Houphou&#235t Boigny d’Abidjan Abidjan C&#244te d’Ivoire Laboratoire d’Océanographie et du Climat: Expérimentations et Approches Numériques Sorbonne Université IRD CNRS MNHN Paris France Université Grenoble Alpes IRD CNRS Grenoble INP IGE Grenoble France UFHB-IRD Joint International Laboratory of Research on NEXUS Climate Water Energy and Agriculture and Development of Cli-mate Services African Centre of Excellence CCBAD (Climate Change Biodiversity and Sustainable Agriculture) Université Félix Houphou&#235t-Boigny Abidjan C&#244te D’Ivoire

The West African Monsoon (WAM) is characterized by strong decadal and multi-decadal variability and the impacts can be catastrophic for the local populations. One of the factors put forward to explain this variability involves the role of atmospheric dynamics, linked in particular to the Saharan Heat Low (SHL). This article addresses this question by comparing the sets of preindustrial control and historical simulation data from climate models carried out in the framework of the CMIP5 project and observations data over the 20th century. Through multivariate statistical analyses, it was established that decadal modes of ocean variability and decadal variability of Saharan atmospheric dynamics significantly influence decadal variability of monsoon precipitation. These results also suggest the existence of external anthropogenic forcing, which is superimposed on the decadal natural variability inducing an intensification of the signal in the historical simulations compared to preindustrial control simulations. We have also shown that decadal rainfall variability in the Sahel, once the influence of oceanic modes has been eliminated, appears to be driven mainly by the activity of the Arabian Heat Low (AHL) in the central Sahel, and by the structure of the meridional temperature gradient over the inter-tropical Atlantic in the western Sahel.

关键词： Influence of Continental Atmospheric Forcing on the Decadal Variability of the West African Monsoon

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Climate Services Elaboration for Cocoa Cultivation in Côte d’Ivoire: Contribution of CORDEX Climate Projections

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Agricultural Sciences 2024年第3期15卷 358-375页

作者： Adama Bamba Fidèle Yoroba N’Datchoh Evelyne Toure Kouakou Kouadio Mory Ouattara Kakou M’bo Mamadou Cherif Daouda Kone Arona diedhiou Laboratoire des sciences de la Matière de l’Environnement et de l’Energie Solaire (LASMES) Université Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire Centre d’Excellence Africain en Changement Climatique Biodiversité et Agriculture Durable (CCBAD) Université Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire Laboratoire Mixte International Climat-Eau-Energy-Agriculture Université Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire Station Géophysique de LAMTO N’Douci C&#244te d’Ivoire UFR Bioscience Université Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire Université Grenoble Alpes IRD CNRS Grenoble-INP IGE Grenoble France

This study assessed the contribution of climate projections to improving rainfall information for cocoa crops in the central and southern regions of Côte d’Ivoire. Particular attention was paid to fourteen localities in these two climatic zones. Simulation data were obtained from the CORDEX ensemble and observation data from CHIRPS. They cover the period 1991-2005 for the reference period and the future period from 2021 to 2050 for the RCP4.5 and RCP8.5 scenarios. In addition, the study was based on the water requirements necessary during the critical phase of the cocoa tree (the flowering phase) for a good yield from the cocoa production chain on the one hand, and on a selection of three climate indices CDD, CWD and r95PTOT to study their spatio-temporal changes over two future periods 2021-2035 (near future) and 2036-2050 (medium-term) on the other. These climatic indices influence cocoa cultivation and their use in studies of climatic impacts on agriculture is of prime importance. The analysis of their spatio-temporal changes in this work also contributes to providing climate services based on rainfall, to which cocoa crops are highly sensitive. Our results show that the CDD and CWD indices vary from one region to another depending on latitude. For the fourteen localities studied, the number of consecutive dry days (CDD) could increase between now and 2050, while the number of consecutive wet days (CWD) could decrease over the period 2021-2035 and then increase over the period 2036-2050. The localities of Tabou, Aboisso and San-Pedro record high numbers of CDD index and CWD index for both projection scenarios. In comparison with the RCP4.5 and RCP8.5 scenarios, these results show that the RCP8.5 scenarios are having an impact on cocoa growing in Côte d’Ivoire.

关键词： Cocoa RCP4.5 RCP8.5 Climate Indices Côte D’ivoire

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Projected Changes in the Climate Zoning of Côte d’Ivoire

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Atmospheric and Climate Sciences 2024年第1期14卷 62-84页

作者： Mamadou Diarrassouba Adama Diawara Assi Louis Martial Yapo Benjamin Komenan Kouassi Fidèle Yoroba Kouakou Kouadio Dro Touré Tiemoko Dianikoura Ibrahim Koné Arona diedhiou Laboratory of Sciences Matter Environment and Solar Energy (LASMES) University Félix Houphou&#235t-Boigny Abidjan C&#244te d’Ivoire Geophysical Station of Lamto (GSL) N’douci C&#244te d’Ivoire Laboratory of Fundamental and Applied Physics University Nangui Abrogoua Abidjan C&#244te d’Ivoire Université Grenoble Alpes (UGA) Institut des Géosciences de l’Environnement (IGE) Institut de Recherche pour le Développement (IRD) Centre National de Recherche Scientifique (CNRS) Institut National Polytechnique (INP) Grenoble France African Centre of Excellence on Climate Change Biodiversity and Sustainable Agriculture (ACE-CCBAD)/University Felix Houphou&#235t-Boigny (UFHB) Abidjan C&#244te d’Ivoire

This study assesses the projected changes in the climate zoning of Côte d’Ivoire using the hierarchical classification of principal components (HCPC) method applied to the daily precipitation data of an ensemble of 14 CORDEX-AFRICA simulations under RCP4.5 and RCP8.5 scenarios. The results indicate the existence of three climate zones in Côte d’Ivoire (the coastal, the centre and the north) over the historical period (1981-2005). Moreover, CORDEX simulations project an extension of the surface area of drier climatic zones while a reduction of wetter zones, associated with the appearance of an intermediate climate zone with surface area varying from 77,560 km2 to 134,960 km2 depending on the period and the scenario. These results highlight the potential impacts of climate change on the delimitation of the climate zones of Côte d’Ivoire under the greenhouse gas emission scenarios. Thus, there is a reduction in the surface areas suitable for the production of cash crops such as cocoa and coffee. This could hinder the country’s economy and development, mainly based on these cash crops.

关键词： Climate Projection Climate Zone Principal Component Analysis Hierarchical Classification on Principal Components CORDEX Côte d’Ivoire

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Case Report: Rhupus (The Association of Systemic Lupus Erythematosus and Rheumatoid Arthritis): About 2 Cases

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Open Journal of Rheumatology and Autoimmune Diseases 2024年第2期14卷 84-88页

作者： Omar Boun Khatab Diouf Mouhamed Dieng Michel Assane Ndour Matar Ndiaye Nousradine Mourno Tarsa Boundia Djiba Ibrahima Mané Diallo Demba diedhiou Anna Sarr Maimouna Ndour Mbaye Internal Medicine Departement Abass Ndao Hospital Dakar Senegal

Introduction: The association of systemic lupus erythematosus and rheumatoid arthritis (rhupus) is a rare clinical condition. Throughout the world, 287 cases of Rhupus have been described. We report two new observations of two patients who presented predominantly distal erosive polyarthritis with positive anti-Sm antibodies in one case and SmRNP in the other case. Observations: Case 1: 37 years old patient, with a recent diagnosis of pulmonary tuberculosis. She has since 8 months an inflammatory, bilaterally and symmetrical polyarthralgia without deformation or ankylosing synovitis, associated with malar erythema without other abnormalities. Immunological tests showed: positive Rheumatoid factor at 158 IU/ml, positive Anti-CCP at 550 IU/ml, and positivity of antinuclear at 1/1280 nuclear fluorescence with a strong presence of anti-Sm >8 IU/ml. The diagnosis of rhupus was concluded, without serious visceral involvement. Case 2: A 28-year-old patient, married with 3 children, with bilateral, symmetrical, deforming and chronic polyarthritis affecting large and small joints, which had been evolving for over 5 years without cutaneous abnormality associated. Paraclinical investigations showed: a biological inflammatory syndrome. Immunology was positive, with rheumatoid factors at 78 IU/ml, anti-CCP at 561 IU/ml, antinuclear antibodies at 1/1280 with positive anti-SmRNP and anti-SSA/Ro52, and a positive direct Coombs test. Joint ultrasound revealed tenosynovitis of the extensors and common flexors of the fingers, erosions and synovitis of multiple PPIs. The diagnosis of rhupus was based on the presence of 10 ACR criteria for RA and 8 ACR/EULAR 2019 criteria for SLE. Conclusion: Rheumatoid arthritis is a rare autoimmune disease combining features of both systemic lupus erythematosus and rheumatoid arthritis in the same patient, often sequentially. Despite a growing number of case reports and series, a consensus on the classification of SLE arthritis is still lacking, and di

关键词： Rhumatoïd Arthritis Lupus Rhupus Connective Tissue Disease

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Diabetic Macroangioapathy at the Internal Medicine Department of the Abass Ndao Hospital Center (About 359 Cases)

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Journal of Diabetes Mellitus 2024年第1期14卷 1-12页

作者： Sow Djiby Djiba Boundia Ndour Michel Assane diedhiou Demba Dieng Mouhamed Diallo Ibrahima Mané Fall Ndiouga Gueye Khoudia Gadji Fatou Kiné Sarr Anna Diop Said Nourou Ndour Mbaye Maimouna Department of Internal Medicine and Medical Specialties H&#244pital Abass Ndao Dakar Senegal

Introduction: Macroangiopathy plays an important role, with a high prevalence of morbidity and mortality in diabetic patients. The aim was to study the epidemiological, clinical, paraclinical, therapeutic and evolutionary profile of macroangiopathy in diabetic patients in the internal medicine department of the Abass Ndao hospital. Patients and methods: This was a descriptive and analytical cross-sectional study. Our investigations were recruited over a 7-year period (January 1, 2016 to December 31, 2022). Results: Three hundred and fifty-nine (359) patients (10.22%) were enrolled. The mean age was 62.83 years, with extremes ranging from 17 to 98 years. The [60 - 69] age group was more representative (37.32%). Women accounted for 180 cases (50.1%), with a sex ratio (m/f) of 0.99. The average duration of diabetes was 11.86 years. Average consultation time was 38.07 days, with extremes ranging from 1 to 368 days. Average hospital stay was 7.65 days. Inaugural diabetes was noted in 12 cases (3.34%). Type 2 diabetes accounted for 95.82% (n = 344) of patients. Hypertension was present in 150 patients (41.8%). Patients with 2 risk factors accounted for 173 cases (48.18%). Nineteen patients had already had a stroke (5.29% of cases). Fourteen (14) patients (4.2%) were amputees. Obliterative arteriopathy of the lower limbs (AOMI) was noted in 193 patients (54%). Stroke was noted in 101 patients (28%). Ischemic heart disease (IHD) was noted in 38 patients (11%). AOMI was more common in males (110 patients, 57%) than in females (43%). Seventy-three (73) patients (20.3%) died. Predictors of death were age over 60 and the existence of more than two cardiovascular risk factors. Conclusion: Diabetic macroangiopathy is a major cause of morbidity and mortality. The development and implementation of a prevention and management program is essential.

关键词： Macroangiopathy Diabetes Risk Factors Senegal

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Prevalence of Depression and Anxiety in Patients with Autoimmune Disease: A Comparative Study with a Diabetic Population

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Open Journal of Internal Medicine 2024年第2期14卷 159-166页

作者： Michel Assane Ndour Mouhamed Dieng Omar Boun Khatab Diouf Léon Birwe Boundia Djiba Ibrahima Mané Diallo Matar Ndiaye Nousradine Mourno Tarsa Djiby Sow Anna Sarr Demba diedhiou Maimouna Ndour Mbaye Service de Mdecine Interne Centre Hospitalier Abass Ndao Dakar Senegal Service de Mdecine Interne Centre Hospitalier Aristide Le Dantec Dakar Senegal

Introduction: Systemic diseases are a variety of heterogeneous autoimmune and/or autoinflammatory diseases and syndromes usually affecting multiple systems and resulting from immune system dysregulation. We evaluated risk factors for depression and anxiety in an autoimmune disease cohort compared with diabetic patients. Patients and Methods: We conducted an observational, cross-sectional, case-control survey comparing two groups: individuals with connective tissue disease (CTD) and diabetic controls who were followed within three Dakar University hospitals during the period from April to June 2023. Results: The sample comprised 106 participants, of whom 51 (48%) had CTD and 55 (52%) served as diabetic controls. In the CTD group, the majority had lupus (19) and rheumatoid arthritis (23). The CTD patients had a mean age of 41.0 years (SD 16.9), while the diabetic patients had a mean age of 55.9 years (SD 11.7), with a significant difference observed (p Conclusion: Compared to a chronic disease, devastating in Africa and evolving over the long term, autoimmune diseases are more strongly and more frequently associated with anxiety and depression. This is a factor to be taken into account in the holistic management of these patients.

关键词： Connective Tissue Disease Lupus Rhumatoid Arthritis Diabetes Depression Anxiety Disability

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