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以技能竞赛为抓手的青年技术人员实验技能培养模式实践

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教育教学论坛 2018年第20期 279-280页

作者：李响陆思恒吕震桂丽李报黄大可杨枫齐威琴沈少辉陈向红贾雪梅安徽医科大学基础医学院安徽合肥230032

当前,不少高校尤其是医学院校都不同程度存在着青年技术人员实际动手能力欠缺、实际操作水平不高等情况,通过多种手段、多种途径,锤炼青年技术人员专业技能,提升实践动手能力,对提高实验教学质量、提升科研水平具有重要意义。

关键词：医学青年竞赛实践

青年女性普通型新型冠状病毒肺炎临床特征及转归分析

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国际呼吸杂志 2020年第13期40卷 978-981页

作者：李传香郭红荣郑泉黄波何芳徐建群王红娟方思黄雅丽程津津周利君李庆云武汉市第三医院呼吸内科 430000 上海交通大学医学院附属瑞金医院呼吸与危重症医学科 200025

目的探讨青年女性普通型新型冠状病毒肺炎临床特征,指导临床诊治。方法回顾性分析2020年1月3日至2020年2月5日在武汉市第三医院诊治的经核酸检测确诊新型冠状病毒肺炎(普通型)并治愈出院的18岁以上、40岁以下女性患者30例,分析其年龄、... 详细信息

目的探讨青年女性普通型新型冠状病毒肺炎临床特征,指导临床诊治。方法回顾性分析2020年1月3日至2020年2月5日在武汉市第三医院诊治的经核酸检测确诊新型冠状病毒肺炎(普通型)并治愈出院的18岁以上、40岁以下女性患者30例,分析其年龄、潜伏期、症状、外周血指标、影像学及治疗与转归特点。结果青年女性新型冠状病毒肺炎患者临床表现以咳嗽、呼吸困难为主(分别为90%、80%)。外周血检查显示白细胞总数及淋巴细胞计数轻度下降,白蛋白下降,胸部CT表现为斑片状或磨玻璃影为主。治疗反应性好,病情多于7~10 d逆转,表现为症状改善、外周血淋巴细胞计数回升,胸部CT渗出性病灶向纤维条索影转变,随后纤维条索影多可在1个月左右明显吸收。结论青年女性新型冠状病毒肺炎常以咳嗽为首发症状,诊治延迟风险大;普通型患者治疗反应性好,预后佳。外周血淋巴细胞计数回升及胸部CT纤维条索影的出现预示疾病逆转,可用于病情转归判断。

关键词：新型冠状病毒肺炎青年女性

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Biomarkers of aging

Science China(Life Sciences) 2023年第5期66卷 893-1066页

作者： Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu Aging Biomarker Consortium(ABC) Beijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijing 100101China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Department of Dermatology Xiangya HospitalCentral South UniversityChangsha 410008China Hunan Key Laboratory of Aging Biology Xiangya HospitalCentral South UniversityChangsha 410008China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008China Clinic Center of Human Gene Research Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Hubei Clinical Research Center of Metabolic and Cardiovascular Disease Huazhong University of Science and TechnologyWuhan 430022China Hubei Key Laboratory of Metabolic Abnormalities and Vascular Aging Huazhong University of Science and TechnologyWuhan 430022China Stem Cell Translational Research Center Tongji HospitalTongji University School of MedicineShanghai 200065China Department of Nuclear Medicine Daping HospitalThird Military Medical UniversityChongqing 400042China CAS Key Laboratory of Nutrition Metabolism and Food SafetyShanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Shanghai Key Laboratory of Maternal Fetal Medicine Clinical and Translational Research Center of Shanghai First Maternity and Infant HospitalFrontier Science Center for Stem Cell ResearchShanghai Key Laboratory of Signaling and Disease ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China The Department of Endovascular Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Key Laboratory of Regenerative Medicine of Ministry of Education Institute of Ageing and Regenerative MedicineJ

Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological *** a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly *** immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this ***,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory *** fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant.

关键词： aging senescence biomarker clock

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一起由腺病毒3型引起的儿童咽结合膜热暴发

疾病监测 2005年第4期20卷 176-179页

作者：刘维斯宋铁周端华刘于飞陈小霜秦鹏哲罗雷陈雄飞周秀珍吴雪红狄飚陈芳广东省广州市疾病预防控制中心广东广州510080

目的分析腺病毒3型引起的咽结合膜热暴发流行病学特征和流行因素。方法通过描述性流行病学分析方法和病例对照的研究方法,对幼儿园发生的咽结合膜热暴发病例进行发病经过和传播因素的调查,采集患者咽拭子进行病毒分离,核酸鉴定,采集血... 详细信息

目的分析腺病毒3型引起的咽结合膜热暴发流行病学特征和流行因素。方法通过描述性流行病学分析方法和病例对照的研究方法,对幼儿园发生的咽结合膜热暴发病例进行发病经过和传播因素的调查,采集患者咽拭子进行病毒分离,核酸鉴定,采集血清进行病毒抗体检测。结果自2004年6月21日～7月19日,幼儿园349名幼儿中共有258人发病,罹患率73.9%。病例分布在不同年级、班别间无差别。流行曲线呈单峰型。在日托幼儿中,参加游泳幼儿的罹患率明显高于未参加游泳的幼儿(X2=28.96,P<0.001),且随游泳次数的增多,罹患率升高。实验室结果,用PCR检测27例病人的咽拭子标本,10份腺病毒基因阳性(37.0%),其中6份进行了基因序列测定,并对获得的基因序列(290bp)进行分析,显示与腺病毒3型同源性达97%,可认为PCR扩增物为3型腺病毒。同时还检出呼吸道合胞病毒、I型副流感病毒等其它病原体。结论此次疫情主要的病原体是腺病毒3型,幼儿主要通过在幼儿园游泳池戏水以及接触传播的途径引起咽结合膜热暴发,同时合并其它多种病原体感染。

关键词：咽结合膜热腺病毒3型暴发 2004年6月呼吸道合胞病毒儿童流行病学特征流行病学分析基因序列测定咽拭子标本 PCR检测腺病毒基因 3型腺病毒 PCR扩增副流感病毒病原体感染幼儿园罹患率流行因素病例对照传播因素

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云南引种黑老虎试验初报

西部林业科学 2017年第3期46卷 155-159页

作者：尹艾萍祁荣频付玉嫔陶观林司马永康张荣贵李思广石文革毛云玲刘冬芬国家林业局云南珍稀濒特森林植物保护和繁育重点实验室云南昆明650201 贵州省黔东南州林业科学研究所贵州凯里556000 红河州林业科学研究所云南蒙自661100

黑老虎为集药、食、观赏等为一体的大型木质藤本植物,十分珍贵。云南的黑老虎种质资源丰富,但野生资源十分稀少,尚未进行人工培育。本文通过从贵州引进由野生变为栽培种的黑老虎分别在昆明和蒙自2地开展引种栽培研究,引种栽培4年中观察... 详细信息

黑老虎为集药、食、观赏等为一体的大型木质藤本植物,十分珍贵。云南的黑老虎种质资源丰富,但野生资源十分稀少,尚未进行人工培育。本文通过从贵州引进由野生变为栽培种的黑老虎分别在昆明和蒙自2地开展引种栽培研究,引种栽培4年中观察黑老虎对环境的适应、生长和生殖的变化。引种试验结果表明,生长1年后的幼藤能耐昆明和蒙自的冬季低温,正常成活;在昆明和蒙自全光照下引种栽培的黑老虎能正常开花结实,幼年期仅有1-2年,后代能育成正常植株。试验结果初步表明,黑老虎在昆明和蒙自露天引种栽培成功,在2地开展黑老虎的人工培育是可行的。

关键词：黑老虎引种栽培全光照栽培

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芒果蒂腐病和炭疽病的抗性诱导

西南农业学报 2001年第3期14卷 56-58页

作者：晏卫红黄思良谢玲岑贞陆广西农科院植保所广西南宁530007

用适宜浓度的草酸或水杨酸在芒果挂果期对叶片和果实进行喷雾处理 ,可显著提高采后芒果对蒂腐病与炭疽病的抗性。在供试浓度范围内 ,对芒果蒂腐病的抗性诱导 ,草酸以 5 3mM的浓度为最好 ,水杨酸则以 0 1mM为最好。对炭疽病 ,草酸以 37m... 详细信息

用适宜浓度的草酸或水杨酸在芒果挂果期对叶片和果实进行喷雾处理 ,可显著提高采后芒果对蒂腐病与炭疽病的抗性。在供试浓度范围内 ,对芒果蒂腐病的抗性诱导 ,草酸以 5 3mM的浓度为最好 ,水杨酸则以 0 1mM为最好。对炭疽病 ,草酸以 37mM、水杨酸以

关键词：芒果蒂腐病炭疽病诱导抗性草酸水杨酸

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腺周口疮的回顾性队列研究

临床口腔医学杂志 2022年第7期38卷 399-403页

作者：刘子建韩莹金建秋郭骧李曼苏莎程喆刘晓丹徐偲鲁明星李淑芳刘行云郭倩云王雨田刘宏伟北京大学口腔医学院·口腔医院口腔黏膜科国家口腔医学中心国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室北京100081 北京医院口腔科北京100005 中国科学院北京市中关村医院口腔科北京100080 中日友好医院口腔科北京100029 首都医科大学附属北京友谊医院口腔科北京100050 北京大学第三医院口腔科北京100083 首都医科大学附属北京朝阳医院口腔科北京100020

目的:比较不同年龄患者的重型复发性阿弗他溃疡(major recurrent aphthous ulcer,MaRAU)(又称腺周口疮)的临床特征。方法:选择2009年1月~2018年12月于北京大学口腔医院就诊并完成≥3年随访的MaRAU患者,收集病史、溃疡的严重程度(病程、... 详细信息

目的:比较不同年龄患者的重型复发性阿弗他溃疡(major recurrent aphthous ulcer,MaRAU)(又称腺周口疮)的临床特征。方法:选择2009年1月~2018年12月于北京大学口腔医院就诊并完成≥3年随访的MaRAU患者,收集病史、溃疡的严重程度(病程、年总间歇时间、年总溃疡个数和年总溃疡面积)、MaRAU的好发部位、伴发或后遗症状及随访期内新出现的全身疾病等信息。结果:共纳入60例MaRAU患者,按MaRAU的发病年龄是否超过40岁分成早发病和迟发病2组,34例纳入早发病组,26例纳入迟发病组。2组的一般情况、相关病史及药物选择上无明显差异。早发病者的MaRAU更好发于口咽部(P=0.022),其溃疡严重程度更高(P<0.050),更易出现张口受限(P=0.011)和吞咽困难(P=0.031),且其中有11例患者(32.4%)出现肠道疾病,显著多于迟发病组(RR=4.206,95%CI:1.019~117.356,P=0.022)。Logistic回归分析显示年龄小于40岁(P=0.021)和MaRAU出现前经常腹泻(P=0.022)是MaRAU发病后出现肠道疾病的危险因素。结论:年轻的MaRAU患者口腔溃疡更为严重,且更容易出现肠道疾病,应积极治疗口腔溃疡,且重视肠道疾病的排查。

关键词：腺周口疮复发性阿弗他溃疡临床特征全身疾病肠道疾病

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu Kaitengsifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise