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Journal of Energy Chemistry 2021年第6期30卷 10-18,I0001页

作者： Yoongon Kim Yuseong Noh Jaejin bae Hyunwoo Ahn Minho Kim Won bae Kim Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)77 Cheongam-roNam-guPohang 37673South Korea

Lithium-sulfur(Li-S)batteries have attracted considerable attention as next-generation energy storage devices owing to their high theoretical specific capacity and ***,the commercialization of Li-S batteries is hindered by critical issues,including the migration of the dissolved lithium polysulfides(LiPSs)from the sulfur electrode to the lithium metal anode,resulting in poor cycling ***,we report a multifunctional interlayer configured with an N-doped carbon framework and titanium nitride nanowires on a polypropylene separator(NC/TiN NWs@PP)to suppress the polysulfide shuttling ***/TiN NWs@PP can be obtained by electrospinning and the subsequent scalable solution-based vacuum *** one-dimensional structure of the TiN NWs can shorten the Li-ion diffusion distance with large electrode/electrolyte ***,the N-doped carbon framework in the NWs enables facile electron transportation and allows the suppression of the shuttle effect to improve the electrochemical reaction *** Li-S battery with a NC/TiN NWs@PP separator exhibited enhanced cycling stability and rate capability,indicating that this could be a new research direction for Li-S batteries.

关键词： Li-S battery Shuttle effect Interlayer Separator TiN N-doped carbon 1D Nanowire

Choroidal and skin metastases from colorectal cancer

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World Journal of Gastroenterology 2016年第43期22卷 9650-9653页

作者： Joo young Ha Edward Hynseung Oh Moon Ki Jung Song Ee Park Ji Tak Kim In gyu Hwang Department of Internal Medicine Chung-Ang University College of Medicine Department of Internal Medicine Division of Hemato-oncology Chung-Ang University College of Medicine Department of Ophthalmology Chung-Ang University College of Medicine

Choroidal and skin metastasis of colon cancer is rare. In women, the frequency of cutaneous metastasis from colon cancer as the primary lesion in is 9% and skin metastasis occurs in 0.81% of all colorectal cancers. We report a patient with colonic adenocarcinoma who presented with visual disorder in her right eye and scalp pain as her initial symptoms. Contrast-enhance orbital magnetic resonance imaging with fat suppression revealed an infrabulbar mass, and skin biopsy of the posterior parietal scalp confirmed adenocarcinoma. These symptoms were diagnosed as being caused by choroidal and skin metastases of colonic adenocarcinoma. We started palliative chemotherapy with oral capecitabine(1000 mg/m2, twice a day, on days 1-14) every 3 wk, which was effective at shrinking the brain masses and improving the visual disorder. This is the first report that capecitabine is effective at reducing a choroidal and cutaneous metastatic lesion from rightsided colorectal cancer.

关键词： Colon cancer Choroid cancer Skin cancer Capecitabine

Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27

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Bone Research 2018年第3期6卷 238-251页

作者： Sung Won Lee Jee Hyun Rho Sang Yeob Lee Won Tae Chung Yoo Jin Oh Jung Ha Kim Seung Hee Yoo Woo young Kwon Ju Yong bae Su young Seo Hokeun Sun Hye young Kim young Hyun Yoo Department of Rheumatology Dong-A University College of Medicine Department of Anatomy and Cell Biology Dong-A University College of Medicine and Mitochondria Hub Regulation Center Department of Microbiology Dong-A University College of Medicine Department of Statistics Pusan National University

Free fatty acids(FFAs), which are elevated with metabolic syndrome, are considered the principal offender exerting lipotoxicity. Few previous studies have reported a causal relationship between FFAs and osteoarthritis pathogenesis. However, the molecular mechanism by which FFAs exert lipotoxicity and induce osteoarthritis remains largely unknown. We here observed that oleate at the usual clinical range does not exert lipotoxicity while oleate at high pathological ranges exerted lipotoxicity through apoptosis in articular chondrocytes. By investigating the differential effect of oleate at toxic and nontoxic concentrations, we revealed that lipid droplet(LD) accumulation confers articular chondrocytes, the resistance to lipotoxicity. Using high fat diet-induced osteoarthritis models and articular chondrocytes treated with oleate alone or oleate plus palmitate, we demonstrated that articular chondrocytes gain resistance to lipotoxicity through protein kinase casein kinase 2(PKCK2)—six-transmembrane protein of prostate 2(STAMP2)—and fat-specific protein 27(FSP27)-mediated LD accumulation. We further observed that the exertion of FFAs-induced lipotoxicity was correlated with the increased concentration of cellular FFAs freed from LDs, whether FFAs are saturated or not. In conclusion, PKCK2/STAMP2/FSP27-mediated sequestration of FFAs in LD rescues osteoarthritic chondrocytes. PKCK2/STAMP2/FSP27 should be considered for interventions against metabolic OA.

关键词： osteoarthritis remains articular chondrocytes

Radial Pulse and Electrocardiography Modulation by Mild Thermal Stresses Applied to Feet: An Exploratory Study with Randomized, Crossover Design

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Chinese Journal of Integrative Medicine 2020年第4期26卷 299-306页

作者： Jang-Han bae Boncho Ku young Ju Jeon Hyunho Kim Jihye Kim Haebeom Lee Jong Yeol Kim Jaeuk U.Kim Korea n Medici ne Fun dame ntal Research Divisi on Korea Institute of Oriental MedicineDaejeon(34054)Republic of Korea Department of Biofunctional Medicine and Diagnostics College of Korea n MedicineKyung Hee UniversitySeoul(02453)Republic of Korea Department of Human Informatics of Korean Medicine Interdisciplinary ProgramsKyung Hee UniversitySeoul(02453)Republic of Korea

Objective:To investigate the changes in radial pulse induced by thermal stresses(TSs).Methods:Sixty subjects were *** an open-label,2x2 crossover randomization design,both feet of each subject were immersed in 15%:water for cold stress(CS)and in 40 X:water for heat stress(HS)for 5 min *** pulse,respiration and electrocardiogram(ECG)signals were recorded before,during and immediately after the ***:The an alysis of heart rate variability revealed that CS in creased the low-freque ncy(LF)and high-frequency(HF)components(P<0.05)and that HS reduced the LF and HF components(P<0.01).Both TSs reduced the normalized LF,increased the normalized HF,and reduced the LF/HF *** differences in the ECG signals were more dominant during the TS sessions,but those in the radial pulse signals became more domi nant immediately after the TS sessi *** decreased the pulse depth(P<0.01)and in creased the radial augme ntation in dex(P<0.1),and HS in creased the pulse pressure(P<0.1)and sube ndocardial viability ratio(P<0.01).There were no significant differences in pulse rate during the three time sequences of each *** respiration rate was increased(P<0.1),and the pulse rate per respiration(P/R ratio)was significantly decreased(P<0.05)with *** HF region(10-30 Hz)of the pulse spectral density was suppressed during both ***:CS induced vasoconstriction and sympathetic reactions,and HS induced vasodilation and parasympathetic reacti *** on defi nitions used in pulse diag no sis,we made the novel discoveries that the pulse became slower(decreased P/R ratio),more floating and tenser under CS and that the HF region of the spectral power decreased significantly under both TSs.

关键词： radial pulse pulse diag no sis thermal stress electrocardiography heart rate variability

“Designing synthetic topological matter with atoms and lights”

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Light(Science & Applications) 2022年第3期11卷 8-9页

作者： Entong Zhao Chengdong He gyu-Boong Jo Department of Physics The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina IAS Center for Quantum Technologies Clear Water BayKowloonHong KongChina

One of the most interesting directions in quantum simulations with ultracold atoms is the expansion of our capability to investigate exotic topological *** sophisticated atom-light couplings in an atomic system,scient... 详细信息

关键词： topological trivial directions

Efficient synthesis of IrPtPdNi/GO nanocatalysts for superior performance in water electrolysis

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Nano Research 2024年第11期17卷 10208-10215页

作者： Sanha Jang young Hwa Yun Jin gyu Lee Kyung Hee Oh Shin Wook Kang Jung-Il Yang MinJoong Kim Changsoo Lee Ji Chan Park Clean Fuel Research Laboratory Korea Institute of Energy Research Daejeon 34129 Korea Hydrogen Research Department Korea Institute of Energy Research Daejeon 34129 Korea Energy Engineering University of Science and Technology Daejeon 34113 Korea

Traditional iridium (Ir) oxide catalysts have faced significant limitations in water electrolysis, particularly under acidic conditions where instability and degradation severely restrict the efficiency of the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER). To overcome these challenges, this study successfully synthesized highly dispersed IrPtPdNi alloy nanoparticles on a graphene oxide support using a vertically moving reactor, demonstrating exceptional performance in water electrolysis. These nanoparticles, synthesized via a fast-moving bed pyrolysis method, combine iridium, platinum, palladium, and nickel. They exhibit lower overpotentials in OER and comparable performance in HER to commercial catalysts, while also offering enhanced stability. These results surpass the limitations of traditional catalysts, marking significant progress toward more efficient and sustainable hydrogen production technologies. This advancement is expected to contribute significantly to the development of sustainable energy systems by innovatively enhancing the performance of catalysts in the electrochemical water-splitting process.

关键词： multicomponent nanoparticles rapid synthesis water electrolysis alloy iridium cat

Retrospective analysis of extra-gastrointestinal stromal tumors

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World Journal of Gastroenterology 2015年第6期21卷 1845-1850页

作者： Jun Ho Yi Byeong-bae Park Jung Hun Kang In gyu Hwang Dong Bok Shin Sun Jin Sym Hee Kyung Ahn Soon Il Lee Do Hyoung Lim Keon Woo Park young-Woong Won Sung Hee Lim Se Hoon Park Division of Hematology-Oncology Department of Internal Medicine Hanyang University Seoul Hospital Division of Hematology-Oncology Department of Internal Medicine Gyeongsang National University School of Medicine Division of Hematology-Oncology Department of Internal Medicine Chung-Ang University Hospital ChungAng University College of Medicine Division of Hematology-Oncology Department of Internal MedicineGachon University Gil Hospital Department of Hematology-Oncology Dankook University School of Medicine Division of Hematology and Oncology Department of Internal Medicine Hanyang University Guri Hospital Hanyang University College of Medicine Division of HematologyOncology Department of Medicine Sungkyunkwan University Samsung Medical Center Cancer hospital

AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors(EGISTs)in South ***:A total of 51 patients with an EGIST were *** clinicopathologic features,including sex,age,location,tumor size,histology,mitotic rate,immunohistochemical features,genetic status and survival data,were ***:The median age was 55 years(range:29-80years),and male:female ratio was 1:*** most common site was in the mesentery(n=15)followed by the retroperitoneum(n=13)and omentum(n=8).The median tumor size was 9.0 cm(range:2.6-30.0cm)and the median mitotic rate was 5.0/50HPF.(1/50-185/50).KIT was analyzed in 16,which revealed 10cases with wild-type KIT and 6 cases with an exon *** 51 patients,31 patients had undergone surgery,and 10 had unresectable disease and had taken palliative imatinib,which resulted in 22.7 mo of progression-free *** the patients who had undergone surgery,18 did not take adjuvant imatinib,and 8 of these were categorized as"high risk"according to the risk ***,the relapse-free survival was not different(P=0.157)between two ***:Because the biologic behaviors of GISTs differ according to the location of the tumor,a more stratified strategy is required for managing EGISTs including incorporation of molecular features.

关键词： Gastrointestinal stromal tumor Survival Imatinib R

ψValuation ideals and primary w-ideals

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Frontiers of Mathematics in China 2016年第4期11卷 829-844页

作者： gyu Whan CHANG Hwaukoo KIM Department of Mathematics Education Incheon National University Incheon 406-772 Republic of Korea Department of Information Security Hoseo University Asan 336-795 Republic of Korea

Let D be an integral domain, ψ（D）（resp., t-ψ（D）） be the set of all valuation （resp., t-valuation） ideals of D, and w-P（D） be the set of primary w-ideals of D. Let D[X] be the polynomial ring over 19, c（f） be the ideal of D generated by the coefficients of f ∈ D[X], and Nv = {f∈ D[X] ｜ c（f）v = D}. In this paper, we study integral domains D in which w-P（D） t-ψ（D）, t-ψ（D） w-P（D）, or t-ψ（D） = w-P（D）. We also study the relationship between t-ψ（D） and ψ（D[X]Nv）, and characterize when t-ψ（A ＋ XB[X]） w-P（A ＋ XB[X]） holds for a proper extension A c B of integral domains.

关键词： t-Valuation ideal primary w-ideal PvMD UMT-domain D[X]Nv

Rolling Stability Enhancement via Balancing Tail for a Water-running Robot

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Journal of Bionic Engineering 2015年第3期12卷 395-405页

作者： Hyungyu Kim Dong gyu Lee TaeWon Seo School of Mechanical Engineering Yeungnam University Gyeongsan 712-749 Republic of Korea

Running on water produces very energy-efficient and fast motion in water environments. Many studies have been performed to develop bio-inspired water-running robots. To achieve good performance, the lifting force is very important for a robot to be able to run on water. The loss of lifting force is associated with the rolling stability of the robot on water. The purpose of this study is to improve the rolling stability of a water-running robot through the periodic motion of a balancing tail. Kinematic analysis was performed to calculate the motions of the legs and the tail, and static analysis was performed to calculate the balancing effect of the tail motion. A numerical model was suggested to determine the dynamic performance of the robotic platform based on kinematic and static results. A simulation based on the numerical model was performed, and the results were compared with empirical data from a robot prototype. The simulation results are in good agreement with the experimental data in terms of rolling stability The lifting force has only a slight effect. The results of this study can be used as a guideline for designing a stable water-running robot.

关键词： water-running robot balancing tail rolling stability lifting force basilisk lizard

Engineering Geometric Electrodes for Electric Field-Enhanced High-Performance Flexible In-Plane Micro-Supercapacitors

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Energy & Environmental Materials 2023年第4期6卷 114-120页

作者： Jihong Kim Sung Min Wi Jong-Guk Ahn Sangjun Son Hee young Lim Yeonsu Park Hye Ji Eun Jong bae Park Hyunseob Lim Sangyeon Pak A-Rang Jang young-Woo Lee Department of Energy Engineering Soonchunhyang UniversityAsan 31538Korea Department of Chemistry Gwangju Institute of Science and TechnologyGwangju 61005Korea Jeonju Centre Korea Basic Science InstituteJeonju 54907Korea Prof.S.Pak School of Electronic and Electrical Engineering Hongik UniversitySeoul 04066Korea Division of Electrical Electronic and Control EngineeringKongju National UniversityCheonan 31080Korea

In plane micro-supercapacitors that are miniaturized energy storage components have attracted significant attention due to their high power densities for various ubiquitous and sustainable device systems as well as their facile integration on various flexible/wearable *** implement the micro-supercapacitors in various practical applications that can accompany solid state or gel electrolyte and flexible substrates,ions must be readily transported to electrodes for achieving high power ***,we show large enhancement in electrochemical properties of flexible,inplane micro-supercapacitor using sharp-edged interdigitated electrode design,which was simply fabricated through direct laser scribing *** sharp-edged electrodes allowed strong electric field to be induced at the corners of the electrode fingers which led to the greater accumulation of ions near the surface of electrode,significantly enhancing the energy storage performance of *** electric field-enhanced in-plane micro-supercapacitor showed the volumetric energy density of 1.52 Wh L^(−1)and the excellent cyclability with capacitive retention of 95.4%after 20000 *** further showed various practicability of our sharp-edged design in micro-supercapacitors by showing circuit applicability,mechanical stability,and air *** results present an important pathway for designing electrodes in various energy storage devices.

关键词： electric field enhancement flexible energy storage device microsupercapacitors sharp electrodes