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Development of a variable rate applicator for uniform fertilizer spreading

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International Journal of Agricultural and Biological Engineering 2019年第2期12卷 82-89页

作者： Cheol-woo Han Sang-yoon Lee young-ki Hong Gi-young Kweon Department of Bio-Industrial Machinery Engineering(Institute of Agriculture and Life Science) Gyeongsang National UniversityJinju 52828Korea Department of Agriculture Engineering National Academy of Agricultural ScienceRDAJeonju 54875Korea

Environmental impact and economic concerns have driven a variable rate technology(VRT).Spinner spreaders were mainly used for granular fertilizer application since they are simple in design,inexpensive,and can cover large ***,the spreader was not adequate for VRT because uniformity changes drastically while varying application ***,the purpose of this study was to develop a variable rate applicator with uniform spreading patterns.A commercial spreader was modified with a controller and electric actuators for controlling fertilizer discharge directions and *** was established to determine the optimum discharge direction according to the fertilizer application *** uniformity of spreading patterns in accordance with the spread amount per set unit area was evaluated by the statistical coefficient of variation(CV)lower than 15%is assumed to prevent damage to the *** results showed that CVs were 8%,9%,and 8%,respectively,for a tractor in race track mode(adjacent passes in same direction of travel)at 200 kg/hm^(2),300 kg/hm^(2),and 400 kg/hm^(2).This indicates that the fertilizer was spread uniformly,while the coefficient of variation was 12%at 200 kg/hm^(2) in back and forth mode(adjacent passes in the opposite direction of travel).Overall,the results suggest that the race track mode is suitable for operation of a tractor to ensure uniform spreading of fertilizer when applying at variable *** future goal is to establish a system for automatic variable rate application according to location in connection with soil analysis and geographic information systems.

关键词： variable rate technology fertilizer application uniform spreading spinner granular applicator fertilizer amount control

KML001, an arsenic compound, as salvage chemotherapy in refractory biliary tract cancers: A prospective study

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Hepatobiliary & Pancreatic Diseases International 2019年第1期18卷 62-66页

作者： Jung Hyun Jo Huapyong kang Hee Seung Lee Moon Jae Chung Jeong Youp Park Seungmin Bang Seung woo Park Si young Song Division of Gastroenterology Department of Internal Medicine Severance Hospital Yonsei University College of Medicine

Background: Sodium meta-arsenite(NaAsO_2, KML001) is a potential oral anticancer agent acting on telomerase and telomere length. This prospective study evaluated its safety, tolerability, and effectiveness as salvage chemotherapy in patients with advanced biliary tract cancer(BTC) resistant to gemcitabinebased chemotherapy. Methods: Forty-four patients(21 women and 23 men) with advanced BTC and failure history of gemcitabine-based chemotherapy, performance status(PS) 0–2, normal cardiac, hepatic, and renal function were enrolled. Daily dose of KML001(7.5 mg. p.o.) was administered to eligible subjects for 24 weeks divided into six treatment cycles. Response was evaluated bimonthly using CT. Results: After an average of 1.5 months of treatment(range: 0.5–10.0), 3 patients(6.8%) obtained progression-free status, 23 patients(52.3%) had disease progression, and 18 patients(40.9%) dropped out before evaluation. One patient(2.3%) completed six treatment cycles without progression. During the treatment, morphine dosage kept the same or decreased in 20 patients(47.6%). Nine patients(20.5%) experienced grade-3 adverse events(AEs), while no patient experienced grade-4 AEs. The most common AEs were liver enzyme elevation(11/44, 25%) and anemia(10/44, 22.7%). KML001 was discontinued in six patients(13.6%) due to AEs, including liver toxicity( n = 3), QTc prolongation( n = 2), and abdominal pain( n = 1). Conclusions: KML001 did not have enough anticancer effect on patients with advanced BTC resistant to gemcitabine. However, KML001 was safe and well-tolerable in terms of AEs and pain control when used as salvage therapy. Further studies are needed to establish arsenic agents as a reliable treatment option in patients with BTC.

关键词： Biliary tract neoplasms Cholangiocarcinoma Gallbladder neoplasms KML001 Sodium meta-arsenite

Structural stability estimation of whirling unit

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中国有色金属学会会刊：英文版 2009年第B9期19卷 202-208页

作者： Son-Jae HWAN Han-Chang woo Lee-Sang RYONG Lee-young MOON Daegu Machinery Institute of Component & Materials Foundation Department of Automobile Yeungnam College of Science & Technology Department of Mechanical Engineering Kyung pook National University

Whirling is a cutting process in which a series of cutting edges on whirling ring remove material by turning over a rotating workpiece. In this study static and dynamic stability of whirling unit was estimated by using ADAMS and NASTRAN softwares. Each maximum force acting on the bearing attached to the spindle assembly and the cutting tool attached to the whirling ring with the rotating speed of 6 000 r/min was 235 N and 902 N respectively. The maximum stress of 0.74 MPa on the base frame is far smaller than the yield strength of 282 MPa. The calculated natural frequency of 148 Hz of the system is far from the frequency of the driving speed of 6 000 r/min. The experimentally obtained maximum cutting force of 792 N is smaller than that of calculated value. And the experimentally obtained natural frequency of 118 Hz is beyond the driving speed of 6000 r/min. From above results it can be judged that the whirling system is statically and dynamically stable.

关键词：旋转工件稳定性评价 NASTRAN软件动态稳定性结构单元固有频率行车速度

The photodynamic therapy on Streptococcus mutans biofilms using erythrosine and dental halogen curing unit

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International Journal of Oral Science 2012年第4期4卷 196-201页

作者： young-Ho Lee Ho-Won Park Ju-Hyun Lee Hyun-woo Seo Si-young Lee Department of Pediatric Dentistry Graduate SchoolCollege of DentistryGangneung-Wonju National University Department of Pediatric Dentistry College of DentistryGangneung-Wonju National University Department of Microbiology and Immunology College of DentistryGangneung-Wonju National University

The purpose of our study was to evaluate the effect of photodynamic therapy （PDT）, using erythrosine as a photosensitizing agent and a dental halogen curing unit as a light source, on Streptococcus mutans in a biofilm phase. The S. mutans biofilms were formed in a 24-well cell culture cluster. Test groups consisted of biofilms divided into four groups： group 1： no photosensitizer or light irradiation treatment （control group）; group 2： photosensitizer treatment alone; group 3： light irradiation alone; group 4： photosensitizer treatment and light irradiation. After treatments, the numbers of colony-forming unit （CFU） were counted and samples were examined by confocal laser scanning fluorescence microscopy （CLSM）. Only group 4 （combined treatment） resulted in significant increases in cell death, with rates of 75% and 55% after 8 h of incubation, and 74% and 42% at 12 h, for biofilms formed in brain-heart infusion （BHI） broth supplemented with 0% or O. 1% sucrose, respectively. Therefore, PDT of S. mutans biofilms using a combination of erythrosine and a dental halogen curing unit, both widely used in dental clinics, resulted in a significant increase in cell death. The PDT effects are decreased in biofilms that form in the presence of sucrose.

关键词： biofilms dental halogen curing unit erythrosine photodynamic therapy Streptococcus mutans

A credit scoring model based on the Myers–Briggs type indicator in online peer-to-peer lending

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Financial Innovation 2022年第1期8卷 1274-1292页

作者： Hyunwoo woo So young Sohn Department of Industrial Engineering Yonsei University134 Shinchon-dongSeoulRepublic of Korea

Although psychometric features have been considered for alternative credit scoring,they have not yet been applied to peer-to-peer(P2P)lending because such information is not available on *** study proposed an alternative credit scoring model for P2P lending by extracting typical personality types inferred from the borrowers’job *** projected a virtual space of borrowers by using the affinity matrix based on the Myers–Briggs type indicator(MBTI)that fits each job *** the distance in this space to Lending Club data,we used locally weighted logistic regression to vary the coefficients of the variables,which affect loan repayments,with each MBTI type for predicting the default *** found that each MBTI type’s credit scoring model has different significant *** study provides insights into breakthroughs in developing alternative credit scoring for P2P lending.

关键词： Alternative credit scoring Behavioral finance Credit scoring Locally weighted logistic regression MBTI P2P lending

Spontaneous resolution of multiple lymphangiomas of the colon:A case report

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World Journal of Gastroenterology 2011年第11期17卷 1515-1518页

作者： Ji Min Lee woo Chul Chung kang-Moon Lee Chang Nyol Paik Yeon-Ji Kim Bo-In Lee young Seok Cho Hyun Joo Choi Department of Internal Medicine College of Medicine the Catholic University of KoreaSt.Vincent's Hospital 93-6Ji dongPaldal-guSuwonGyeonggi-do442-723South Korea

Lymphangioma of the colon is a relatively rare nonepithelial tumor and usually presents as a submucosal polypoid *** cases incidentally discovered are usually ***,they may present as abdominal pain or bleeding,and their resection is normally *** itself is generally recognized as a benign tumor and no cases of malignant transformation have yet been reported,although its natural history is currently *** the best of our knowledge,this study is the first to describe a case of spontaneous resolution in multiple colonic lymphangiomas without any specific treatment.

关键词： Lymphangioma Colon Natural history

Asian facial recontouring surgery

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Plastic and Aesthetic Research 2023年第1期10卷 83-95页

作者： Jong-woo Choi young-Chul Kim Department of Plastic and Reconstructive Surgery Ulsan University College of MedicineAsan Medical CenterSeoul 138-736Republic of Korea

Most East Asian women prefer a smaller and smoother facial *** meet this aesthetic preference,the concept and surgical techniques of modern facial bone contouring surgery have ***,facial bone contouring surgery was limited to procedures like mandibular angle and malar ***,contemporary Asian facial bone contouring surgery now places a stronger emphasis on addressing the entire facial profile from a three-dimensional perspective,a concept referred to as *** this article,we review the evolution of surgical techniques in Asian facial bone contouring surgery and present its current surgical concepts,particularly focusing on the three-dimensional aspects.

关键词： Asian bone contouring profiloplasty mandibuloplasty malarplasty genioplasty

Invasive and non-invasive diagnosis of cirrhosis and portal hypertension

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World Journal of Gastroenterology 2014年第15期20卷 4300-4315页

作者： Moon young Kim woo Kyoung Jeong Soon Koo Baik Department of Internal Medicine Yonsei University Wonju College of MedcineWonju Severance Christan HospitalWonju 220-701South Korea Department of Radiology and Center for Imaging Science Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 440-746South Korea

With advances in the management and treatment of advanced liver disease,including the use of antiviral therapy,a simple,one stage description for advanced fibrotic liver disease has become *** refining the diagnosis of cirrhosis to reflect disease heterogeneity is essential,current diagnostic tests have not kept pace with the progression of this new *** biopsy and hepatic venous pressure gradient measurement are the gold standards for the estimation of hepatic fibrosis and portal hypertension(PHT),respectively,and they have diagnostic and prognostic ***,they are invasive and,as such,cannot be used repeatedly in clinical *** ideal noninvasive test should be safe,easy to perform,inexpensive,reproducible as well as to give numerical and accurate results in real *** should be predictive of long term outcomes related with fibrosis and PHT to allow prognostic ***,many types of noninvasive alternative tests have been developed and are under *** particular,imaging and ultrasound based tests,such as transient elastography,have shown promising *** most of these noninvasive tests effectively identify severe fibrosis and PHT,the methods available for diagnosing moderate disease status are still insufficient,and further investigation is essential to predict outcomes and individualize therapy in this field.

关键词： Hepatic fibrosis Portal hypertension Liver biopsy Hepatic venous pressure gradient Non-invasive test Transient elastography

Electrical and Corrosion Properties of Titanium Aluminum Nitride Thin Films Prepared by Plasma-Enhanced Atomic Layer Deposition

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Journal of Materials Science & Technology 2017年第3期33卷 295-299页

作者： Eun-young Yun woo-Jae Lee Qi Min Wang Se-Hun Kwon School of Materials Science and Engineering Pusan National University School of Electromechanical Engineering Guangdong University of Technology

Titanium-aluminum-nitride（TiAlN） films were grown by plasma-enhanced atomic layer deposition（PEALD）on 316 L stainless steel at a deposition temperature of 200 °C. A supercycle, consisting of one AlN and ten TiN subcycles, was used to prepare TiAlN films with a chemical composition of Ti（0.25）Al（0.25）N（0.50）. The addition of AlN to TiN resulted in an increased electrical resistivity of TiAlN films of 2800 μΩ cm, compared with 475 μΩ cm of TiN films, mainly due to the high electrical resistivity of AlN and the amorphous structure of TiAlN. However, potentiostatic polarization measurements showed that amorphous TiAlN films exhibited excellent corrosion resistance with a corrosion current density of 0.12 μA/cm^2, about three times higher than that of TiN films, and about 12.5 times higher than that of 316 L stainless steel.

关键词： Titanium-aluminum nitride Plasma-enhanced atomic layer deposition Corrosion protection Ternary transition metal nitrides