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Alloy design for laser powder bed fusion additive manufacturing:a critical review

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International journal of Extreme Manufacturing 2024年第2期6卷 29-63页

作者： Zhuangzhuang Liu Qihang Zhou Xiaokang Liang Xiebin Wang Guichuan Li kim Vanmeensel jianxin Xie Key Laboratory for Advanced Materials Processing(MOE) Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing 100083People’s Republic of China Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083People’s Republic of China Beijing Laboratory of Metallic Materials and Processing for Modern Transportation Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing 100083People’s Republic of China Capital Aerospace Machinery Corporation Limited Beijing 100076People’s Republic of China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJingshi Road 17923Jinan 250061People’s Republic of China Department of Materials Engineering KU LeuvenLeuven 3001Belgium

Metal additive manufacturing(AM)has been extensively studied in recent *** the significant progress achieved in manufacturing complex shapes and structures,challenges such as severe cracking when using existing alloys for laser powder bed fusion(L-PBF)AM have *** challenges arise because commercial alloys are primarily designed for conventional casting or forging processes,overlooking the fast cooling rates,steep temperature gradients and multiple thermal cycles of *** address this,there is an urgent need to develop novel alloys specifically tailored for L-PBF *** review provides a comprehensive summary of the strategies employed in alloy design for *** aims to guide future research on designing novel alloys dedicated to L-PBF instead of adapting existing *** review begins by discussing the features of the L-PBF processes,focusing on rapid solidification and intrinsic heat ***,the printability of the four main existing alloys(Fe-,Ni-,Al-and Ti-based alloys)is critically assessed,with a comparison of their conventional *** was found that the weldability criteria are not always applicable in estimating ***,the review presents recent advances in alloy development and associated strategies,categorizing them into crack mitigation-oriented,microstructure manipulation-oriented and machine learning-assisted ***,an outlook and suggestions are given to highlight the issues that need to be addressed in future work.

关键词： laser powder bed fusion alloy design printability crack mitigation

Gender-and Age-Group Specific Association of Persistent Organic Pollutants(POPs)Exposure with Diabetes Mellitus:Korean National Environmental Health Survey(KoNEHS)2015−2017

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Environment & Health 2024年第5期2卷 322-331页

作者： Inae Lee Min joo kim Sohyeon Choi young joo Park jeongim Park Gökçe Nur Ayaz Gowoon Lee Yoon Hee Cho Hye Li jeon Chulwoo Lee Gi jeong Cheon Min Kyong Moon Kyungho Choi Graduate School of Public Health Seoul National UniversitySeoul 08826Republic of Korea Institute of Health and Environment Seoul National UniversitySeoul 08826Republic of Korea Department of Internal Medicine Seoul National University College of MedicineSeoul 03080Republic of Korea Seoul National University Hospital Healthcare System Gangnam Center Seoul 06236Republic of Korea Department of Environmental Health Sciences Soonchunhyang UniversityAsan 31538Republic of Korea Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and TechnologySeoul National UniversitySeoul 08826Republic of Korea Center for Environmental Health Sciences Department of Biomedical and Pharmaceutical SciencesUniversity of MontanaMissoulaMontana 59812United States Environmental Health Research Division National Institute of Environmental ResearchMinistry of EnvironmentIncheon 22689Republic of Korea Department of Nuclear Medicine Seoul National University College of MedicineSeoul 03080Republic of Korea Division of Endocrinology Department of Internal MedicineSeoul National University Boramae Medical CenterSeoul 07061Republic of Korea

Exposure to persistent organic pollutants(POPs)has been reported as a potential risk factor for diabetes in ***,effect modifications by sex and age,especially among Asian populations,have seldom been *** the present study,we assessed associations of major POPs exposure including organochlorine pesticides(OCPs),polychlorinated biphenyls(PCBs),and polybrominated diphenyl ethers(PBDEs),with diabetes in Korean adults(n=1,295),a subset of the Korean National Environmental Health Survey(KoNEHS)Cycle 3(2015−2017).In the adult population,serum levels of dichlorodiphenyltrichloroethanes(DDTs)and PCB167 showed an increased odds ratio(OR)for *** stratified by gender,associations became stronger and more consistent in women:In women,serum levels of OCPs including p,p′-DDT,p,p′-dichlorodiphenyldichloroethylene(p,p′-DDE),andΣOCPs and mono-ortho PCBs,such as PCB118 and PCB157,were significantly associated with *** the male participants,however,no significant positive associations were *** stratified by a cutoff age of 50 years,most studied POPs except PBDEs,i.e.,p,p′-DDT,p,p′-DDE,PCB118,PCB157,PCB167,PCB138,and PCB153,showed significant associations with diabetes,in the older *** the younger group,however,no measured POPs showed a significant positive *** of endogenous sex hormones or interaction of POPs on aryl hydrocarbon receptors may partly explain the observed differences by gender and age,although further experimental confirmations should *** findings show that POPs exposure at the current levels is associated with diabetes among general Korean adults,and such associations could be modified by gender and age.

关键词： persistent organic pollutants diabetes age gender toxicity equivalency factor

Effect of atractylenolide Ⅲ on zearalenone-induced Snail1-mediated epithelial–mesenchymal transition in porcine intestinal epithelium

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journal of Animal Science and Biotechnology 2024年第5期15卷 2081-2092页

作者： Na Yeon kim Myoung Ok kim Sangsu Shin Woo‑Sung Kwon Bomi kim joon Yeop Lee Sang In Lee Department of Animal Science and Biotechnology Kyungpook National UniversitySangjuGyeong‑sangbuk‑do37224Republic of Korea Research Institute for Innovative Animal Science Kyungpook National UniversitySangjuGyeongsangbuk‑do 37224Republic of Korea National Institute for Korean Medicine Development Gyeongsan 38540Republic of Korea

Background The intestinal epithelium performs essential physiological functions,such as nutrient absorption,and acts as a barrier to prevent the entry of harmful *** are prevalent contaminants found in ani-mal feed that exert harmful effects on the health of ***(ZEA)is produced by the Fusarium genus and induces gastrointestinal dysfunction and disrupts the health and immune system of ***,we evaluated the molecular mechanisms that regulate the effects of ZEA on the porcine intestinal *** Treatment of IPEC-j2 cells with ZEA decreased the expression of E-cadherin and increased the expression of Snai1 and Vimentin,which induced Snail1-mediated epithelial-to-mesenchymal transition(EMT).In addition,ZEA induces Snail-mediated EMT through the activation of TGF-β*** treatment of IPEC-j2 cells with atractyle-nolideⅢ,which were exposed to ZEA,alleviated *** Our findings provide insights into the molecular mechanisms of ZEA toxicity in porcine intestinal epi-thelial cells and ways to mitigate it.

关键词： Atractylenolide III Epithelial–mesenchymal transition IPEC-j2 cells Snail TGF-beta signaling Zearalenone

On von Neumann Regularity of Commutators

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Algebra Colloquium 2024年第2期31卷 181-198页

作者： Nam Kyun kim Tai Keun Kwak Yang Lee Sung ju Ryu Nanqing Ding School of Basic Sciences Hanbat National UniversityDaejeon 34158Korea Department of Data Science Daejin UniversityPocheon 11159Korea Department of Mathematics Yanbian UniversityYanjiJilin 133002China Institute for Applied Mathematics and Optics Hanbat National University Daejeon 34158Korea Department of Mathematics Pusan National UniversityBusan 46241Korea 不详

We study the structure of rings which satisfy the von Neumann regularity of commutators,and call a ring R C-regularif ab-ba ∈(ab-ba)R(ab-ba)for all a,b in *** a C-regular ring R,we prove j(R[X])=N^(*)(R[X])=N^(*)(R)[X]=W(R)[X]■Z(R[X]),where j(A),N^(*)(A),W(A),Z(A)are the jacobson radical,upper nilradical,Wedderburn radical,and center of a given ring A,respectively,and A[X]denotes the polynomial ring with a set X of commuting indeterminates over A;we also prove that R is semiprime if and only if the right(left)singular ideal of R is *** provide methods to construct C-regular rings which are neither commutative nor von Neumann regular,from any given ***,for a C-regular ring R,the following are proved to be equivalent:(i)R is Abelian;(ii)every prime factor ring of R is a duo domain;(ii)R is quasi-duo;and(iv)R/W(R)is reduced.

关键词： C-regular ring commutator regular ring commutative ring radical singular ideal

Development of immature ovarian teratoma after mature teratoma in a girl with familial ovarian teratoma:A case report

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World journal of Clinical Cases 2024年第8期12卷 1442-1447页

作者： U Chul ju Woo Dae Kang Seok Mo kim Department of Obstetrics and Gynecology Chonnam National University Medical SchoolGwangju 61469South Korea

BACKGROUND Immature ovarian teratoma is a rare and aggressive neoplasm that affects young *** report is the first to describe the development of immature teratoma after ovarian cystectomy for mature teratoma of the ovary in an adolescent female with a family history of ovarian *** SUMMARY A 16-year-old girl who had undergone bilateral ovarian cystectomy for mature teratomas 3 years ago showed bilateral adnexal tumors during her regular ultrasonography follow-up every 6 *** received laparoscopic bilateral ovarian cystectomy,and final histopathology showed grade-1 immature teratoma of the left ovary and mature teratoma of the right *** left salpingo-oophorectomy and staging procedures were performed *** mother,maternal aunt,and maternal grandmother had also received surgeries for mature ovarian *** It is important to have guidance on management of patient and family members with familial ovarian teratomas.

关键词： Familial ovarian teratomas Adolescent female Immature ovarian teratoma Management Case report

Effects of mesenchymal stem cell on dopaminergic neurons,motor and memory functions in animal models of Parkinson's disease:a systematic review and meta-analysis

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Neural Regeneration Research 2024年第7期19卷 1584-1592页

作者： jong Mi Park Masoud Rahmati Sang Chul Lee jae Il Shin Yong Wook kim Department and Research Institute of Rehabilitation Medicine Yonsei University College of MedicineSeoulSouth Korea Department of Physical Education and Sport Sciences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran Department of Pediatrics Yonsei University College of MedicineSeoulSouth Korea

Parkinson’s disease is chara cterized by the loss of dopaminergic neurons in the substantia nigra pars com pacta,and although restoring striatal dopamine levels may improve symptoms,no treatment can cure or reve rse the disease *** cell therapy has a regenerative effect and is being actively studied as a candidate for the treatment of Parkinson’s *** stem cells are considered a promising option due to fewer ethical concerns,a lower risk of immune rejection,and a lower risk of *** performed a meta-analysis to evaluate the therapeutic effects of mesenchymal stem cells and their derivatives on motor function,memory,and preservation of dopamine rgic neurons in a Parkinson’s disease animal *** searched bibliographic databases(PubMed/MEDLINE,Embase,CENTRAL,Scopus,and Web of Science)to identify articles and included only pee r-reviewed in vivo interve ntional animal studies published in any language through j une 28,*** study utilized the random-effect model to estimate the 95%confidence intervals(CI)of the standard mean differences(SMD)between the treatment and control *** use the systematic review center for laboratory animal expe rimentation’s risk of bias tool and the collaborative approach to meta-analysis and review of animal studies checklist for study quality assessment.A total of 33studies with data from 840 Parkinson’s disease model animals were included in the *** with mesenchymal stem cells significantly improved motor function as assessed by the amphetamine-induced rotational *** the stem cell types,the bone marrow MSCs with neurotrophic factor group showed la rgest effect size(SMD[95%CI]=-6.21[-9.50 to-2.93],P=0.0001,I^(2)=0.0%).The stem cell treatment group had significantly more tyrosine hydroxylase positive dopamine rgic neurons in the striatum([95%CI]=1.04[0.59 to 1.49],P=0.0001,I^(2)=65.1%)and substantia nigra(SMD[95%CI]=1.38[0.89 to 1.87],P=0.0001,I^(2)=75.3%),indicating a

关键词： animal animal experimentation mesenchymal stem cells models Parkinson’s disease stem cell transplantation

Efficacy and safety of low-dose tetracycline,amoxicillin quadruple therapy in Helicobacter pylori infection:A retrospective single center study

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World journal of Gastroenterology 2024年第39期30卷 4295-4304页

作者： Yi-Ru Zhao Xin-jie Wang Meng-jia Zhu Ang-Li Chen Dian Zhang Qin Du john j.kim Wei-Ling Hu Department of Gastroenterology Sir Run Run Shaw HospitalMedical SchoolZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina Department of Gastroenterology The First Affiliated HospitalMedical SchoolZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina Department of Gastroenterology The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Keck School of Medicine University of Southern CaliforniaLos AngelesCA 90089-9021United States Institute of Gastroenterology Zhejiang UniversityHangzhou 310016Zhejiang ProvinceChina

BACKGROUND Helicobacter pylori(***)eradication rates have declined with the rise of antibiotic-resistant strains in recent *** highly effective with a low prevalence of resistance,standard dose tetracycline is associated with frequent adverse *** efficacy and safety of low-dose tetracycline as part of tetra-cycline and amoxicillin-containing bismuth quadruple therapy are not well *** To compare the efficacy and safety of low-dose compared to standard dose tetracycline with combined amoxicillin-containing bismuth quadruple therapy in patients with *** *** Consecutive patients with *** infection receiving tetracycline,amoxicillin,proton pump inhibitor,and bismuth for 14 days at Sir Run Run Shaw Hospital(1/2022-6/2023)were *** low-dose tetracycline group received tetracycline 500 mg twice daily(bid)while the standard dose group received 750 mg bid or 500 mg three times daily(tid).Primary endpoints were *** eradication rate and treatment-related adverse events.

关键词： Helicobacter pylori Tetracycline Amoxicillin Eradication Adverse events Bismuth quadruple therapy

Long-term olfactory loss post-COVID-19:Pathobiology and potential therapeutic strategies

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World journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 148-155页

作者： Sarah kim john B.Finlay Tiffany Ko Bradley j.Goldstein Department of Head and Neck Surgery&Communication Sciences Duke UniversityDurhamNorth CarolinaUSA Medical Scientist Training Program Duke UniversityDurhamNorth CarolinaUSA Department of Neurobiology Duke UniversityDurhamNorth CarolinaUSA

An acute loss of smell emerged as a striking symptom present in roughly half of the people infected with the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)virus in the early phases of the COVID-19 *** most COVID-19 patients,olfaction recovers over the course of a few ***,a lasting partial or complete loss of smell,often associated with distorted olfactory perceptions termed parosmia,has emerged as a widespread problem impacting at least 5%-10%of those who experience anosmia due to *** inability to offer effective therapies to this hyposmic or anosmic population,comprising millions of patients,highlights an enormous unmet need for the medical ***,we summarize the current understanding of the pathobiology causing acute olfactory loss due to SARS-CoV-2 infection,focusing on how the virus interacts with the peripheral olfactory system,a major site of viral *** also explore the problem of long-COVID olfactory dysfunction,which may accompany other persistent systemic disorders collectively termed postacute sequelae of ***,we discuss an emerging model focused on unresolved immune cell activity driving ongoing ***,we review current and future therapeutic approaches aimed at restoring olfactory function.

关键词： hyposmia inflammation long-COVID parosmia

Vertical plane depth-resolved surface potential and carrier separation characteristics in flexible CZTSSe solar cells with over 12% efficiency

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Carbon Energy 2024年第3期6卷 36-52页

作者： Dae-Ho Son Ha Kyung Park Dae-Hwan kim jin-Kyu Kang Shi-joon Sung Dae-Kue Hwang jaebaek Lee Dong-Hwan jeon Yunae Cho William jo Taeseon Lee junHo kim Sang-Hoon Nam Kee-jeong Yang Division of Energy Technology DGISTDaeguRepublic of Korea Research Center for Thin Film Solar Cells DGISTDaeguRepublic of Korea Department of Physics Ewha Womans UniversitySeoulRepublic of Korea Department of Physics Incheon National UniversityIncheonRepublic of Korea Department of Mechanical Engineering Massachusetts Institute of TechnologyCambridgeMassachusettsUSA

Cu2ZnSn(S,Se)4(CZTSSe)solar cells have resource distribution and economic *** main cause of their low efficiency is carrier loss resulting from recombination of photo-generated electron and *** overcome this,it is important to understand their electron-hole behavior *** determine the carrier separation characteristics,we measured the surface potential and the local current in terms of the absorber *** elemental variation in the intragrains(IGs)and at the grain boundaries(GBs)caused a band edge shift and bandgap(Eg)*** the absorber surface and subsurface,an upward Ec and Ev band bending structure was observed at the GBs,and the carrier separation was *** the absorber center,both upward Ec and Ev and downward Ec-upward Ev band bending structures were observed at the GBs,and the carrier separation was *** improve the carrier separation and suppress carrier recombination,an upward Ec and Ev band bending structure at the GBs is desirable.

关键词： carrier separation CZTSSe flexible solar cell local current surface potential