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Primary intestinal lymphangiectasia diagnosed by capsule endoscopy and double balloon enteroscopy

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World Journal of Gastrointestinal Endoscopy 2011年第11期3卷 235-240页

作者： Tak Geun Oh Joo Won Chung Hee Man Kim Seok-Joo Han Jin Sung Lee jung Yeob Park Si young Song Division of Gastroenterology Department of Internal MedicineYonsei Institute of GastroenterologyYonsei University College of MedicineSeoul 120-752South Korea epartment of Pediatric Surgery Yonsei University College of MedicineSeoul 120-752South Korea Department of Pediatrics Yonsei University College of MedicineSeoul 120-752South Korea Division of Gastroenterology Department of Internal MedicineBrain Korea 21 Project for Medical Science and Severance Biomedical Science InstituteYonsei University College of MedicineSeoul 120-752South Korea

Primary intestinal lymphangiectasia(PIL)is a rare disorder characterized by dilated intestinal lymphatics and the development of protein-losing *** with PIL develop hypoalbuminemia,hypocalcemia,lymphopenia and hypogammaglobulinemia,and present with bilateral lower limb edema,fatigue,abdominal pain and *** reveals diffusely elongated,circumferential and polypoid mucosae covered with whitish enlarged villi,all of which indicate intestinal *** is conf irmed by characteristic tissue pathology,which includes dilated intestinal lymphatics with diffusely swollen mucosa and enlarged *** prevalence of PIL has increased since the introduction of capsule *** etiology and prevalence of PIL remain *** studies have reported that several genes and regulatory molecules for lymphangiogenesis are related to *** report the case of a patient with PIL involving the entire small bowel that was confirmed by capsule endoscopy and double-balloon enteroscopy-guided tissue pathology who carried a deletion on chromosome *** relationship between this deletion on chromosome 4 and PIL remains to be investigated.

关键词： Capsule endoscopy Double balloon enteroscopy Chromosome deletion Chromosome 4q25 Primary intestinal lymphangiectasia

预防性使用地塞米松可降低双腔气管导管拔管后咽痛及声嘶发生率

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麻醉与镇痛 2010年第2期6卷 57-61页

作者： Sang Hyun Park, MD Sung-Hee Han, MD, PhD Sang-Hwan Do, MD, PhD jung-Won Kim, MD, PhD Ka-young Rhee, MD, PhD Jin-Hee kim, MD, PhD 陈亮(译) 陈畅(校) 王焱林(校) Department of Anesthesiology and Pain Medicine Seoul National University Bundang Hospital Seongnam City Kyeonggi-do Department of Anesthesiology and Pain Medicine Inje University llsan Paik Hospital Goyang City Kyeonggi-do Department of Anesthesiology and Pain Medicine Konkuk University School of medicine Seoul Korea 不详

背景：手术后咽痛及声嘶是气管插管，特别是双腔气管导管插管后的主要并发症。我们开展此项前瞻、随机、双盲的安慰剂对照研究，来评价地塞米松用以降低手术后咽痛及声嘶发生率和严重程度的效能。方法本研究选择了166例（18～75岁）使... 详细信息

背景：手术后咽痛及声嘶是气管插管，特别是双腔气管导管插管后的主要并发症。我们开展此项前瞻、随机、双盲的安慰剂对照研究，来评价地塞米松用以降低手术后咽痛及声嘶发生率和严重程度的效能。方法本研究选择了166例（18～75岁）使用双腔气管导管插管的胸外科手术患者。在全麻诱导之前，以双盲、前瞻性的随机方法分为地塞米松（静脉给予）0．1mg／kg组（D1组）、0．2mg／kg组（D2组）和安慰剂组（P组）。分别记录Cormack—Lehane评分的声门暴露度、双腔管插管阻力、尝试插管次数、完成插管时间以及插管维持时间。在拔管后1及24小时，利用视觉模拟评分（VAS，0=没有疼痛；100=可以想象的最剧烈疼痛）来评价咽痛及声嘶程度。结果拔管1小时后，咽痛、声嘶发生率及咽痛程度与P组（53％，36％，VAS30．9）相比，D1组（31％，P=0．021；11％，P=0．003；VAS12．4，P〈0．001）与D2组（11％，P=0．001；4％，P=0．001；VAS6．6，P〈0．001）均低。拔管24小时后，D2组（27％，P=0．002；15％，P=0．001；VAS29．9，P〈0．002）咽痛、声嘶发生率及咽痛程度显著低于D1组（47％，31％，VAS43．9）及P组（57％，45％，VAS51．3）。同时未发现与注射地塞米松相关的并发症的发生。结论预防性使用0．2mg／kg地塞米松能显著降低双腔气管导管拔管后１及24小时咽痛、声嘶发生率及严重程度。

关键词：双腔气管导管地塞米松预防性使用发生率拔管后咽痛声嘶视觉模拟评分

传统与现代视野中的身体想象与女性解放——论鲁迅与张恨水小说中的女性形象

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廊坊师范学院学报（社会科学版） 2014年第6期30卷 10-15页

作者：薛熹祯北京大学外国语学院

20世纪是一个动荡不安的时代。为了实现富国自强,女性作为一股长期被忽视的力量得到前所未有的重视。不少"五四"女青年完成了由贤妻良母到新女性的转换,从幕后走上社会大舞台,以实现救亡图存的理想。鲁迅以个性解放、人道主义开启了中... 详细信息

20世纪是一个动荡不安的时代。为了实现富国自强,女性作为一股长期被忽视的力量得到前所未有的重视。不少"五四"女青年完成了由贤妻良母到新女性的转换,从幕后走上社会大舞台,以实现救亡图存的理想。鲁迅以个性解放、人道主义开启了中国人对新的身体存在形式的构想。张恨水则写了一系列女性积极谋生的作品,在一定程度上是对女性"出走"以后怎么办的解答。可以说,鲁迅是客观、清醒地思考女性命运的,但由于未能完全摆脱传统的男性视角,而无法真正进入女性的内心世界;张恨水则填补了鲁迅留下来的空白,他从女性立场去书写女性内在的精神创伤,并回答了"出走"以后怎么办的问题。

关键词：鲁迅张恨水女性解放身体想象思想教育

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一款全新多效气垫粉凝霜的人体功效研究

日用化学品科学 2017年第1期40卷 36-40页

作者：夏雪郭一荣陈雪郑煆镇延在昊爱茉莉太平洋(上海)研发有限公司上海201801

对一种具有全面肤质提升作用的长效气垫粉凝霜进行了功效评价。在广州地区选择21名25~40岁具有彩妆使用习惯的女性,在产品使用前和使用后12 h对皮肤水分、肤色、光泽度、毛孔状况及细纹深度和数量进行了分析;同时考察了使用产品后皮肤... 详细信息

对一种具有全面肤质提升作用的长效气垫粉凝霜进行了功效评价。在广州地区选择21名25~40岁具有彩妆使用习惯的女性,在产品使用前和使用后12 h对皮肤水分、肤色、光泽度、毛孔状况及细纹深度和数量进行了分析;同时考察了使用产品后皮肤表面温度变化情况并就满意度对受试者进行了问卷调查。结果表明,该产品能显著提高肌肤水分,改善肤色,细化毛孔和皮肤纹理,实现较好的遮盖效果并保持长效妆容,并可通过降低皮肤表面温度来提供良好的清凉感。多于85%的受试者对该产品的整体效果表示满意,专业的临床评价也显示该产品安全性高,无受试者出现不良反应。

关键词：气垫粉凝霜改善肤质清凉感长效临床评价

生理盐水对多层螺旋CT冠状动脉成像中主动脉和冠状动脉强化的影响

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放射学实践 2008年第7期23卷 821-821页

作者： Dae jung Kim Tae hoon Kim Sang Jin Kim 古今(译) 史河水(校) 不详华中科技大学同济医学院附属协和医院

目的：前瞻性探讨加注生理盐水的注射流率对多层螺旋CT冠状动脉成像中主动脉和冠状动脉强化的影响。方法：本研究获得了医学伦理委员会的批准，所有患者都签署了知情同意书。100个连续病例（男59例，女41例，平均年龄58±11岁）因冠状... 详细信息

目的：前瞻性探讨加注生理盐水的注射流率对多层螺旋CT冠状动脉成像中主动脉和冠状动脉强化的影响。方法：本研究获得了医学伦理委员会的批准，所有患者都签署了知情同意书。100个连续病例（男59例，女41例，平均年龄58±11岁）因冠状动脉疾病行64层螺旋CT冠状动脉成像。根据注人生理盐水的流率（3、4、5、6和7ml／s）将所有病例分成5组（每组20例）。首先以4ml／s的注射流率经静脉注人碘对比剂60m1，接着根据组别分别以3～7ml／s的注射流率经静脉加注60ml生理盐水。分别测量主动脉根部、右冠状动脉、左冠状动脉前降支和回旋支的CT值，应用Scheff6方差分析，

关键词：冠状动脉成像多层螺旋CT 主动脉根部生理盐水医学伦理委员会冠状动脉前降支注射流率冠状动脉疾病

一项对比从富马酸替诺福韦二吡呋酯(TDF)转换为丙酚替诺福韦(TAF)和继续TDF治疗用于病毒学抑制的慢性乙型肝炎(CHB)患者的3期研究:第48周时的疗效和安全性结果

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一项对比从富马酸替诺福韦二吡呋酯(TDF)转换为丙酚替诺福韦(TAF)...

第十届全国疑难及重症肝病大会

作者： Pietro Lampertico Maria Buti Scott Fung Sang hoon Ahn Wan-Long Chuang Won young Tak Alnoor Ramji Chi-Yi Chen Edward Tam Ho Bae Xiaoli Ma John F.Flaherty Anuj Gaggar Audrey Lau Becket Feierbach George Wu Vithika Suri Mani Subramanian Cong Cheng Huy N.Trinh Seung Kew Yoon Kosh Agarwal young-Suk Lim Henry Chan Università degli Studi di Milano Division of Gastroenterology and Hepatology University Hospital Vall d'Hebron University Health Network Yonsei University Kaohsiung Medical University

背景和目的TAF是替诺福韦(TFV)的一种新型前体药物,近期获批用于治疗慢性乙型肝炎。与TDF相比,TAF的血浆稳定性更高,能够更有针对性地将TFV递送至肝脏且降低了TFV的循环水平。第48周和第96周时,TAF表现出不劣于TDF的疗效且改善肾脏和骨...

背景和目的TAF是替诺福韦(TFV)的一种新型前体药物,近期获批用于治疗慢性乙型肝炎。与TDF相比,TAF的血浆稳定性更高,能够更有针对性地将TFV递送至肝脏且降低了TFV的循环水平。第48周和第96周时,TAF表现出不劣于TDF的疗效且改善肾脏和骨骼安全性。本研究评估了从TDF转换为TAF vs.继续接受1年TDF治疗用于病情稳定的病毒学抑制患者时的疗效和安全性。

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乐高,在系统中建立创意

艺术与设计 2023年第7期1卷 118-123页

作者：金真希朴恩星尹美妍(图) 郑佑荣(图) 信勋(图) 刘祖龙(翻译) 不详

在所有砖块的大小和颜色都相同的前提下,六块乐高砖能够创造出多达915103765种组合,两块乐高砖就可以创造出24种不同的组合。换句话说,不同尺寸和颜色的砖块在创造变化方面几乎没有限制。乐高砖块的生产量如今已经达到人均八十块。从193... 详细信息

在所有砖块的大小和颜色都相同的前提下,六块乐高砖能够创造出多达915103765种组合,两块乐高砖就可以创造出24种不同的组合。换句话说,不同尺寸和颜色的砖块在创造变化方面几乎没有限制。乐高砖块的生产量如今已经达到人均八十块。从1932年创立至今,在近百年的时间里,乐高已经成为全球最畅销的玩具大王。

关键词：乐高砖块不同尺寸生产量近百年颜色

An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease

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Hepatobiliary Surgery and Nutrition 2023年第3期12卷 386-403,I0014-I0016页

作者： Dan-Qin Sun Giovanni Targher Christopher D.Byrne David C.Wheeler Vincent Wai-Sun Wong Jian-Gao Fan Herbert Tilg Wei-Jie Yuan Christoph Wanner Xin Gao Michelle T.Long Mehmet Kanbay Mindie H.Nguyen Sankar D.Navaneethan Yusuf Yilmaz Yuli Huang Rino A.Gani Pierluigi Marzuillo Jérôme Boursier Huijie Zhang Chan-young jung Jin Chai Luca Valenti George Papatheodoridis Giovanni Musso Yu-Jun Wong Mohamed El-Kassas Nahum Méndez-Sánchez Silvia Sookoian Michael Pavlides Ajay Duseja Adriaan G.Holleboom Junping Shi Wah-Kheong Chan Yasser Fouad Junwei Yang Sombat Treeprasertsuk Helena Cortez-Pinto Masahide Hamaguchi Manuel Romero-Gomez Mamun Al Mahtab Ponsiano Ocama Atsushi Nakajima Chunsun Dai Mohammed Eslam Lai Wei Jacob George Ming-Hua Zheng Department of Nephrology Jiangnan University Medical CenterWuxiChina Affiliated Wuxi Clinical College of Nantong University WuxiChina Section of Endocrinology Diabetes and MetabolismDepartment of MedicineAzienda Ospedaliera Universitaria Integrata VeronaVeronaItaly Southampton National Institute for Health and Care Research Biomedical Research Centre University Hospital Southamptonand Southampton General HospitalUniversity of SouthamptonSouthamptonUK Department of Renal Medicine University College LondonLondonUK Department of Medicine and Therapeutics Chinese University of Hong KongHong KongChina Center for Fatty Liver Department of GastroenterologyXin Hua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Internal Medicine I GastroenterologyEndocrinology&MetabolismMedical University InnsbruckInnsbruckAustria Department of Nephrology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Division of Nephrology Department of MedicineWürzburg University ClinicWürzburgGermany Department of Endocrinology and Metabolism Zhongshan HospitalFudan UniversityShanghaiChina Section of Gastroenterology Boston Medical CenterBoston University School of MedicineBostonMAUSA Division of Nephrology Department of Medicine(M.K.)Koc University School of MedicineIstanbulTurkey Division of Gastroenterology and Hepatology Department of MedicineStanford University Medical CenterPalo AltoCAUSA Department of Epidemiology and Population Health Stanford University Medical CenterPalo AltoCAUSA Section of Nephrology and Institute of Clinical and Translational Research Baylor College of Medicineand Michael E.DeBakey VA Medical CenterHoustonTXUSA Department of Gastroenterology School of MedicineMarmara UniversityIstanbulTurkey Department of Gastroenterology School of MedicineRecep Tayyip Erdoğan UniversityRizeTurkey Department of Cardiology Shunde HospitalSouthern Medical UniversityFoshanChina Division of Hepat

Background:With the rising global prevalence of fatty liver disease related to metabolic dysfunction,the association of this common liver condition with chronic kidney disease(CKD)has become increasingly *** 2020,the more inclusive term metabolic dysfunction-associated fatty liver disease(MAFLD)was proposed to replace the term non-alcoholic fatty liver disease(NAFLD).The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without ***,to date,there is no appropriate guidance on CKD in individuals with ***,there has been little attention paid to the link between MAFLD and CKD in the Nephrology *** and Results:Using a Delphi-based approach,a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and ***:This Delphi-based consensus statement provided guidance on the epidemiology,mechanisms,management and treatment of MAFLD and CKD,as well as the relationship between the severity of MAFLD and risk of CKD,which establish a framework for the early prevention and management of these two common and interconnected diseases.

关键词： Metabolic dysfunction-associated fatty liver disease(MAFLD) non-alcoholic fatty liver disease(NAFLD) chronic kidney disease(CKD) consensus

Sexually Transmitted Diseases at Monkey Bay Community Hospital in Mangochi, Malawi;an Analysis of Characteristics of Common Sexually Transmitted Diseases

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Advances in Infectious Diseases 2020年第4期10卷 243-252页

作者： David S. Chung Min jung Koh Sung Hwan Chough Seog In Moon Gene K. Lee Ivy Kim Yujin Kim Jae Hee Kim Lorie Kim Hyunjin Kim Eunice Kang Fatsani Manase Thomas Nyirenda School of Medicine University of Virginia Charlottesville VA USA Youth with Talents Fairfax VA USA School of Medicine Georgetwon University Washington DC USA College of Dentistry NYU New York NY USA Clinical Research Education and Management Service Lilongwe Malawi

We present the characteristics of the commonly diagnosed sexually transmitted infections (STI) at a clinic of Monkey Bay community hospital by a retrospective study. We conducted an audit of patients’ hospital records from a STIs clinic at Monkey Bay community hospital in Mangochi District (Malawi) covering a period from January 2019 to June 2019 (18 months). Data was tabulated in excel and analyses were made based on sex, age, male circumcision status, pregnancy and the pattern of STIs diagnosed within the chosen study period. A total number of 659 clients presented at STI clinic of Monkey Bay community hospital between January 2018 and June 2019. Out these clients, 409 (62%) were females and 250 (38%) were males. Most of the patients were in the age range of 25 years or above (447, 68%). Majority of the patients were HIV negative (523, 79%). Out of the 250 males, 113 (45%) were circumcised. Among female patients 56 of the 409 (14%) were pregnant. The most common presentations for all cases put together were lower abdominal pain (253, 38%), then urethral discharge (189, 29%), abnormal vaginal discharge (141, 21%), genital ulcer disease (64, 10%), in that order. Syphilis, genital warts, inguinal bubo and scrotal swelling were less common. The most common presentation in males was urethral discharge (178, 71%), while in females it was lower abdominal pain (214, 52%). Our audit showed that in Mangochi (Malawi) sexually transmitted diseases of various types are more common among young adults, females and uncircumcised men. There was no much difference in the percentage of STI’s between HIV positive and HIV negative people. These results point to an alarmingly high level of risky sexual behaviors among sexually active age groups in this part of Malawi, a country which still has one of the highest HIV prevalence in sub-Saharan Africa. This calls for continued and better research and control for transmission of STIs in the district.

关键词： Sexually Transmitted Infections (STIs) Mangochi Malawi