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Ma xianghua:A Talented Erhu Instrumentalist

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China & The World Cultural Exchange 2006年第2期72卷 42-43页

作者： san san

The artis＇s profile：Ma xianghua bom in Jinan Shandong Piovince is a famous young erhu （two stiing violin ）instrumentalist and teacher at china Central Conseivatory of Music （CCM）.She began iearning erhu to 7 and... 详细信息

关键词：二胡演奏家个人简历马向华中国演奏风格

Undiagnosed Borrmann type Ⅱ gastric cancer due to necrosis and regenerative epithelium

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World Journal of Gastroenterology 2014年第28期20卷 9621-9625页

作者： Joon Hur Jae Hyuck Chang Byung Kee Kim Hoon young ko Jong Hwan Lee Soo Jeong Kim Mi Ae Song Tae Ho Kim Chang Whan Kim Sok Won Han Division of Gastroenterology Department of Internal MedicineBucheon St.Mary’s HospitalThe Catholic University of KoreaCollege of Medicine Department of Clinical Pathology Bucheon St.Mary’s HospitalThe Catholic University of KoreaCollege of Medicine

Endoscopic biopsy is essential to the proper diagnosis and treatment of gastric ***,the results of endoscopic biopsy are not always the same as what is expected based on gross endoscopic *** results of endoscopic biopsy can be negative for malignancy in Borrmann typeⅣadvanced gastric cancer(AGCa)or gastric ***,in the case of typeⅡAGCa,repeated biopsies negative for malignancy have not been reported.A 49-year-old male patient underwent esophagogastroduodenoscopy three times due to large gastric ulcer suspected to be Borrmann typeⅡ***,three repeat endoscopic biopsies with multiple specimens showed necrosis and superficial regenerative epithelium without malignant *** patient underwent laparoscopic distal gastrectomy with D2 lymph node *** surgical specimen revealed that the mucosal layer was completely replaced with regenerative epithelium without cancer cells.

关键词： Endoscopy Biopsy Stomach neoplasm Stomach ulcer Regeneration

Long-term antibiotic use and risk of hepatocellular carcinoma later in life: a nationwide cohort study of 9.8 million participants

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Cancer Communications 2023年第10期43卷 1174-1177页

作者： Seogsong Jeong Sun Jae Park Minseo Kim young Jun Park Seulggie Choi Jooyoung Chang Ji Soo Kim Yun Hwan Oh Ahryoung ko sang Min Park Department of Biomedical Sciences Seoul National University HospitalSeoul National University College of MedicineSeoulSouth Korea Department of Biomedical Informatics CHA University School of MedicineSeongnamSouth Korea Department of Medicine College of MedicineJeonbuk National UniversityJeonjuSouth Korea Medical Research Center Genomic Medicine InstituteSeoul National UniversitySeoulSouth Korea Department of Internal Medicine Seoul National University HospitalSeoul National University College of MedicineSeoulSouth Korea International Healthcare Center Seoul National University HospitalSeoul National University College of MedicineSeoulSouth Korea Department of Family Medicine Chung-Ang University Gwangmyeong HospitalChung-Ang University College of MedicineGwangmyeongSouth Korea Department of Family Medicine Seoul National University HospitalSeoulSouth Korea

Dear Editor,Antibiotics are considered indispensable in numerous treatments against infectious ***,their over-prescription and widespread use are emerging as important global issues,as they lead to resistant bacteria,reducing the efficacy of antibiotics[1].The defined daily doses per 1,000 habitants per day for antibiotics in South korea is 28,which is much higher than the average of Organization for Economic Co-operation and Development countries[1].In animal studies,antibiotic tigecycline was found to inhibit the proliferation and induce apoptosis of hepatocellular carcinoma(HCC)cells[2].In addition,isoprenoid antibiotic was found to suppress the growth and invasion of HCC by targeting the signal transducer and activator of the transcription 3 signaling cascade[3].Despite evidence of the beneficial effects of antibiotics against HCC,evidence regarding their effects on the longterm development of HCC is *** regarding the incidence of HCC is provided in the Supplementary file.

关键词： doses invasion nationwide

Ti_(3)C_(2)T_(x)/SnO_(2)P–N heterostructure construction boosts room-temperature detecting formaldehyde

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Rare Metals 2024年第1期43卷 267-279页

作者： Yue Zhang Ming-Yue Wang Xiao-Guang san Yan-Bai Shen Guo-Sheng Wang Lei Zhang Dan Meng College of Chemical Engineering Shenyang University of Chemical TechnologyShenyang 110142China Institute for Superconducting and Electronic Materials(ISEM) Australian Institute for Innovative Materials(AIIM)University ofWollongongWollongongNSW2500Australia College of Resources and Civil Engineering Northeastern UniversityShenyang 110819China

Formaldehyde is a common atmospheric pollutant produced in industrial production and daily ***,the traditional semiconductor formaldehyde gas sensor cannot work at room temperature,which limits its practical ***,developing high-performance gas sensors for rapidly and accurately detecting formaldehyde at room temperature is an important *** this study,Ti_(3)C_(2)Tx/SnO_(2)heterostructures were constructed,which could selectively detect formaldehyde at room temperature with a response value of 29.16%(10×10^(-6)).In addition,the sensor shows a remarkable theoretical detection limit of 5.09×10^(-9)and good longterm *** functional theory(DFT)simulations reveal that SnO_(2)nano spheres provide the majority of adsorption sites that strongly interact with ***,Ti_(3)C_(2)T_(x)acting as a conductive layer facilitates the transfer of charge carriers so that they show a sensing response to formaldehyde at room ***,the formation of p-n heterostructures between SnO_(2)and Ti_(3)C_(2)T_(x)boosts the Schottky barrier at the interface,which is the critical factor in enhancing the sensing properties by turning the Schottky barrier upon introducing formaldehyde *** perspective is expected to provide instructive guidance for utilizing MXene/metal oxide nanocomposites to improve the gas sensing performance at room temperature.

关键词： Ti_(3)C_(2)T_(x)/SnO_(2)nanocomposites p-n heterostructures Formaldehyde sensing Room temperature DFT calculations

Fundamental electronic structure and multiatomic bonding in 13 biocompatible high-entropy alloys

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npj Computational Materials 2020年第1期6卷 1296-1305页

作者： Wai-Yim Ching Saro san Jamieson Brechtl Ridwan Sakidja Miqin Zhang Peter K.Liaw Department of Physics and Astronomy University of Missouri Kansas CityKansas CityMO 64110USA The Bredesen Center for Interdisciplinary Research and Graduate Education The University of TennesseeKnoxvilleTN 37996-3394USA Department of Physics Astronomy and Materials ScienceMissouri State UniversitySpringfieldMO 65897USA Department of Materials Science and Engineering The University of WashingtonSeattleWA 98195USA Department of Materials Science and Engineering The University of TennesseeKnoxvilleTN 37996-2100USA

High-entropy alloys(HEAs)have attracted great attention due to their many unique properties and potential *** nature of interatomic interactions in this unique class of complex multicomponent alloys is not fully developed or *** report a theoretical modeling technique to enable in-depth analysis of their electronic structures and interatomic bonding,and predict HEA properties based on the use of the quantum mechanical metrics,the total bond order density(TBOD)and the partial bond order density(PBOD).Application to 13 biocompatible multicomponent HEAs yields many new and insightful results,including the inadequacy of using the valence electron count,quantification of large lattice distortion,validation of mechanical properties with experiment data,modeling porosity to reduce young’s *** work outlines a road map for the rational design of HEAs for biomedical applications.

关键词： alloys bonding entropy

Dual PINK Mutant and A<i>β</i>42-Dependent Lifespan Shorten and Flight Impairment in Transgenic Drosophila Partially Alleviates by a <i>Lactococcus lactis</i>Supplemented Diet

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Journal of Behavioral and Brain Science 2015年第7期5卷 266-273页

作者： Dong Gyun ko young Bum Eun Jong Uk Na sang-Tae Kim korean Minjok Leadership Academy Hoengseong-Gun Republic of Korea Department of Neuropsychiatry Bundang Hospital of Seoul National University College of Medicine Biomedical Research Institute Seongnam City Republic of Korea

Oxidative stress has been strongly related with Parkinson disease (PD) and Alzheimer disease pathogenesis. We determined the effects of Lactococcus lactis (LAL) supplementation on the generated loss-of-function mutants of PINK1 B9, an AR-JP-linked gene and Aβ42 induced phenotypes in a Drosophila melanogaster model of PD/AD. Enhanced mutant PINK1 B9 and Aβ42 expression in D. melanogaster dopaminergic (DA) neurons can curtail lifespan, flight muscle accompanied by locomotive defects and we have observed longevity methods to assay the effects of LAL on D. melanogaster survival. Furthermore, flies expressing mutant PINK1 B9 and Aβ42 in their brain fed LAL had up to the two weeks, or 25%, greater median lifespan than those fed a standard sucrose diet. In addition, LAL improved mutant PINK1 B9 and Aβ42-induced flight impairments in the Drosophila wing. Our microscopy analyses revealed that individuals fed LAL had improved atypical ommatidia as well as an increased thirteen percentage of flight ability than those fed a control diet. We propose that LAL, rich in naturally occurring probiotics and antioxidants, promotes the survival of neurons in brain and wing muscle tissues with increased levels of mutant PINK1 B9 and Aβ42 via a protective cell survival mechanism.

关键词： Drosophila melanogaster Lactococcus lactis PINK1 Lifespan Ommatidia Aβ42

Crashworthiness of innovative hexagonal honeycomb-like structures subjected to out-of-plane compression

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Journal of Central South University 2020年第2期27卷 621-628页

作者： WANG Zhong-gang SHI Chong DING san-san LIANG Xi-feng CRRC Qingdao Sifang Co. Ltd.Qingdao 266111China Key Laboratory of Traffic Safety on Track(Ministry of Education) School of Traffic and Transportation EngineeringCentral South UniversityChangsha 410075China

Seeking for innovative structures with higher mechanical performance is a continuous target in railway vehicle crashworthiness *** the present study,three types of hexagonal reinforced honeycomb-like structures were developed and analyzed subjected to out-of-plane compression,namely triangular honeycomb(TH),double honeycomb(DH)and full inside honeycomb(FH).Theoretical formulas of average force and specific energy absorption(SEA)were constructed based on the energy minimization *** validate,corresponding numerical simulations were carried out by explicit finite element *** agreement has been observed between *** results show that all these honeycomb-like structures maintain the same collapsed stages as conventional honeycomb;cell reinforcement can significantly promote the performance,both in the average force and SEA;full inside honeycomb performs better than the general,triangular and double schemes in average force;meanwhile,its SEA is close to that of double scheme;toroidal surface can dissipate higher plastic energy,so more toroidal surfaces should be considered in design of thin-walled *** achievements pave a way for designing high-performance cellular energy absorption devices.

关键词： honeycomb-like structure crashworthiness basic fold element structural reinforcement

View Direction Adaptive 360 Degree Video Streaming System Based on Projected Area

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Journal of Computer and Communications 2018年第1期6卷 203-212页

作者： san Kim Jihyeok Yun Bokyun Jo Ji Ho Kim Ho Gyun Chae Doug young Suh College of Electronics and Information Kyung-Hee University Youn-in Republic of Korea

360 video streaming services over the network are becoming popular. In particular, it is easy to experience 360 video through the already popular smartphone. However, due to the nature of 360 video, it is difficult to provide stable streaming service in general network environment because the size of data to send is larger than that of conventional video. Also, the real user's viewing area is very small compared to the sending amount. In this paper, we propose a system that can provide high quality 360 video streaming services to the users more efficiently in the cloud. In particular, we propose a streaming system focused on using a head mount display (HMD).

关键词： 360 Panoramic Video Cloud Split Image Real-Time Streaming MPU

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常山根水提物在大鼠肝脏中的抗炎作用

Acta Pharmacologica Sinica 2003年第2期24卷 127-132页

作者： CHOI Byung-Tae LEE Jun-Hyuk ko Woo-Shin KIM young-Hee CHOI Yung-Hyun KANG Ho-Sung KIM Han-Do Department of Anatomy College of Oriental Medicaine dongEui Universtity Busan 614-052 kore. Department of Oriental Medicine College of Oriental Medicine Research Institute of Oriental Medicine Dong-Eui University Busan 614-052 Department of Oriental Medicine College of Oriental Medicine Research Institute of Oriental Medicine Dong-Eui University Busan 614-052 Department of Molecular Biology College of Natural Sciences Pusan National University Busan 609-735 korea Department of Molecular Biology College of Natural Sciences Pusan National University Busan 609-735 korea Department of Molecular Biology College of Natural Sciences Pusan National University Busan 609-735 korea Department of Molecular Biology College of Natural Sciences Pusan National University Busan 609-735 korea

AIM: To study the anti-inflammatory effects of aqueous extract from Dichroafebrifuga root (AEDF) for suppression in the process of lipopolysaccharide (LPS)-induced sepsis in the rat liver. METHODS: The inhibitory effect of AEDF on the alteration of inflammatory proteins was investigated by Western blot and immunohistochemical analysis. RESULTS: Western blot analysis showed that the level of nuclear factor (NF)-κBp65 was markedly up-regulated and (Ⅰ)κBα was down-regulated by LPS (8 mg/kg) challenge. However, AEDF 100 mg/kg inhibited induction of NF-κBp65 and degradation of Ⅰ-κBα in the liver of LPS-challenged rats. Immunohistochemical analysis showed that while the expression of the NF-κBp65, tumor necrosis factor (TNF)-α, and inducible nitric oxide synthase(iNOS) tended to increase, that of Ⅰ-κBα was decreased in the hepatocytes of rats challenged with LPS. A slight decline of NF-κBp65, TNF-α, and iNOS, but an increase of Ⅰ-κBα were observed in the hepatocytes of the rats pretreated with AEDF. CONCLUSION: AEDF may act as a therapeutic agent for inflammatory disease through a regulation of inflammation-related proteins.

关键词：常山炎症脂多糖类核因子-кB IкB 肿瘤坏死因子一氧化氮合酶