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Synchronous pancreatic solid pseudopapillary neoplasm and intraductal papillary mucinous neoplasm

World Journal of Gastroenterology 2013年第21期19卷 3358-3363页

作者： Kenichi Hirabayashi Giuseppe Zamboni Hiroyuki Ito Masami Ogawa yoshiaki Kawaguchi Tomohiro Yamashita Toshio Nakagohri Naoya Nakamura Department of Pathology Tokai University School of MedicineIsehara 259-1193Japan Department of Pathology Ospedale Sacro Cuore Don Calabria37024 Negrar VeronaItaly Department of Pathology University of Verona37134 Negrar VeronaItaly Department of Gastroenterology Tokai University School of MedicineIsehara 259-1193Japan Department of Radiology Tokai University School of MedicineIsehara 259-1193Japan Department of Gastroenterological Surgery Tokai University School of MedicineIsehara 259-1193Japan

Solid pseudopapillary neoplasm (SPN) is a rare and low-grade malignant pancreatic neoplasm composed of poorly cohesive monomorphic neoplastic cells forming solid and pseudopapillary structures with frequent hemorrhagic-cystic degeneration. Intraductal papillary mucinous neoplasm (IPMN) is a pancreatic exocrine tumor composed of intraductal papillary growth of mucin containing neoplastic cells in the main pancreatic duct or its major branches. In the case presented here, a 53-year-old, Japanese man was found to have multiple cystic lesions and dilatation of the main pancreatic duct in the neck of the pancreas. Histological examination revealed a main-duct and branch-duct type IPMN, of the gastric-type, involving the neck of the pancreas, associated with a 0.5 cm SPN in the caudal side of the IPMN. We diagnosed this case as synchronous SPN and IPMN. As far as we know, only one other case of synchronous SPN and IPMN has been reported. Both the present case and the previously reported case showed abnormal nuclear expression of β-catenin in SPN, whereas IPMN showed no abnormal nuclear expression. These results suggest that β-catenin abnormality is not a common pathogenetic factor of synchronous SPN and IPMN.

关键词： Intraductal papillary mucinous neoplasms Solid pseudopapillary neoplasms Pancreatic neoplasms Synchronous neoplasms Pancreas Beta-catenin

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Developing Spline Based Overset Grid Assembling Approach and Application to Unsteady Flow Around a Moving Body

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Journal of Mathematics and System Science 2016年第9期6卷 339-347页

作者： Hiroshi Kobayashi yoshiaki Kodama National Maritime Research Institute 6-38-1 Mitaka Tokyo 181-0004 Japan Kodama Fluid Dynamics Design Office Yurinoki St. 1-4-2 Akashi Hyogo 674-0068 Japan

Overset or Chimera grid approach is one of methods to cope with complex geometries. A spline based overset grid assembling system has been developed. The system is based on structured grid approach and covers comprehensive features for overset assembling, i.e., grid generation, grid modification, and computing Domain Connectivity Information （DCI） for overset interpolation. Ferguson spline curve is used to compute curves through grid points and cell centers for trimming grids and computing DCI robustly and accurately. Flow simulation around Kriso Container Ship （KCS） with jointed grids shows good continuity of flow field between the grids. The overset grid assembling is enhanced to unsteady problem as dynamic overset approach coupled with a solver which also has been developed in National Maritime Research Institute, Japan. Computed results for pitchup spheroid are compared with measured data and show good agreement in unsteady force acting on the spheroid. It is confirmed that the system has capability to simulate flow field around jointed grids and unsteady flow with dynamic overset assembling approach practically.

关键词： Overset Assembling Dynamic Overset Unsteady Flow

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Characterization of a <i>Tos</i>17 Insertion Mutant of Rice Auxin Signal Transcription Factor Gene, <i>OsARF</i>24

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American Journal of Plant Sciences 2013年第1期4卷 84-91页

作者： Tomoaki Sakamoto yoshiaki Inukai Faculty of Bioresources and Environmental Sciences Ishikawa Prefectural University Nonoichi Japan Graduate School of Bioagricultural Sciences Nagoya University Nagoya Japan

Auxin signaling plays a key role in the regulation of various growth and developmental processes in higher plants. Auxin response factors (ARFs) are transcription factors that regulate the expression of auxin-response genes. The osarf24-1 mutant contains a truncation of domain IV in the C-terminal dimerization domain of a rice ARF protein, OsARF24. This mutant showed auxin-deficient phenotypes and reduced sensitivity to auxin. However, OsARF24 protein contains an SPL-rich repression domain in its middle region and acts as a transcriptional repressor. These results imply that the C-terminal dimerization domain, especially the C-terminal half of domain IV, is essential for the proper regulation of OsARF24 function as a transcriptional repressor in rice.

关键词： Auxin Auxin Response Factor (ARF) Mutant Phyllotaxis Retrotransposon Tos17 Rice

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Experimental Investigation on Noise Suppression in Supersonic Jets from Convergent-Divergent Nozzles with Baffles

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Journal of Thermal Science 2003年第3期12卷 260-263,269页

作者： yoshiaki Miyazato Yong-Hun Kweon Toshiyuki Aoki Mitsuharu Masuda Kwon-Hee Lee Heuy-Dong Kim Toshiaki Setoguchi Kazuyasu Matsuo Graduate School of Engineering Sciences Kyushu University 6-1 Kasuga-kouen Kasuga Fukuoka816-8580 JapanSchool of Mechanical Engineering Andong National University 388 Songchun-dong AndongKyungbuk 760-749 KoreaGraduate School of Engineering Sciences Kyushu University 6-1 Kasuga-kouen Kasuga Fukuoka816-8580 JapanGraduate School of Engineering Sciences Kyushu University 6-1 Kasuga-kouen Kasuga Fukuoka816-8580 JapanDepartment of Mechanical Engineering Saga University 1 Honjo-machi Saga Saga 840-8502 JapanSchool of Mechanical Engineering Andong National University 388 Songchun-dong AndongKyungbuk 760-749 KoreaDepartment of Mechanical Engineering Saga University 1 Honjo-machi Saga Saga 840-8502 JapanFaculty of Environmental Engineering The University of Kitakyushu 1-1 Hibikino Wakamatsu-kuKitakyushu Fukuoka 808-0135 Japan

The acoustic properties of supersonic jet noise from a convergent-divergent nozzle with a baffle have been studied experimentally over the range of nozzle pressure ratios from 2.0 to 8.0. Acoustic measurements were conducted in a carefully designed anechoic room providing a free-field environment. A new approach for screech noise suppression by a cross-wire is proposed. Schlieren photographs were taken to visualize the shock wave patterns in the supersonic jet with and without the cross-wire. The effects of the baffle and the cross-wire on acoustic properties are discussed. It is shown that the baffle has little effect on the screech frequency for the underexpanded supersonic jet without the cross-wire. Also, the cross-wire introduced in supersonic jets is found to lead to a significant reduction in overall sound pressure level.

关键词：超音速流动噪声控制实验研究收敛-扩散喷管流体力学超音速喷射

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NMR Studies on Diffusion and Molecular Motions of Imidazolium Ionic Liquids doped by Lithium Salts Related to Ionic Conductivity and Computational Interaction Energy

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复旦学报（自然科学版） 2007年第5期46卷 671-页

作者： Kikuko Hayamizua Seiji tsuzuki Shiro Seki National Institute of Advanced Industrial Science and Technology AIST Tsukuba Center 5 Tsukuba 305-8565Japan Materials Science Research Laboratory Central Research Institute of Electric Power Industry (CRIEPI) Iwado-kitaKomaeTokyo 201-8511Japan

1 Results Room-temperature Ionic liquids (RTILs) are special class of compounds, where a combination of cations and anions produces neutral, stable and viscous liquids with high ionic conductivity. Widely spread applications are proposed to use conductors, electrolytes, clean solvents and others. Especially, RTILs are expected to be safe electrolytes in the ion-lithium batteries. In this study, NMR methods are used to clarify the basic properties of the individual movements of the anions and cations of ...

关键词： NMR imidazolium ionic liquid lithium salts

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Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure

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Nano Research 2022年第5期15卷 4201-4211页

作者： Tsukasa Akasaka Miho Tamai Yoshitaka Yoshimura Natsumi Ushijima Shinichiro Numamoto Atsuro Yokoyama Hirofumi Miyaji Ryo Takata Shuichi Yamagata yoshiaki Sato Ko Nakanishi Yasuhiro Yoshida Department of Biomaterials and Bioengineering Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Immune Signal Unit Okinawa Institute of Science and Technology Graduate UniversityOkinawa 904-0495Japan Department of Pharmacology Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Support Section for Education and Research Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Oral Functional Prosthodontics Division of Oral Functional ScienceFaculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Periodontology and Endodontology Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Orthodontics Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan

The surface topography of a material can influence osteoclast ***,the surface structural factors that promote osteoclast activity have not yet been investigated in ***,we investigated osteoclastogenesis by testing various defined patterns with different dimensions and *** systematic patterns,made of a cyclo-olefin polymer,were prepared at a micron-,submicron-,and nano-scale with a groove,hole,or pillar shape with a 1:1 pitch ***264.7 cells were cultured on these patterns in the presence of the receptor activator of NF-κB ligand(RANKL).Osteoclast formation was induced in the order:pillar>groove≥*** two-dimensional factors also indicated that submicron-sized patterns strongly induced osteoclast *** optimal pillar dimension for osteoclast formation was 500 nm in diameter and 2μm in ***,we observed two types of characteristic actin structure,i.e.,belt-like structures with small hollow circles and isolated ring-like structures,which formed on or around the pillars depending on size and ***,resorption pits were observed mainly on the top of calcium phosphate-coated ***,osteoclasts prefer convex shapes,such as pillars for differentiation and *** results indicate that osteoclastogenesis can be controlled by designing surfaces with specific morphologies.

关键词： micro/nano-pattern pillar RAW264.7 osteoclast actin structure resorption pit

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Evaluation of Prognostic Factor for Perforation Closure Rate in Patient with Chronic Otitis Media

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第5期3卷 307-310页

作者： Hirokazu Katsura Yasuo Mishiro Miki Ikehata Kenzo tsuzuki Masafumi Sakagami Hyogo College of Medicine Nishinomiya Japan

Objective: To evaluate factors affecting the perforation closure rate for perforated otitis media. Methods: Between 2008 and 2012, a total of 118 patients with perforated chronic otitis media underwent tympanoplasty at Hyogo College of Medicine Hospital by a single surgeon. Prognostic factors were analyzed using multivariate analysis with logistic regression. Results: The success rate for tympanic perforation was 93.2%. Factors showing significance on multivariate analysis were dryness of perforation and patient age at the time of surgery. Conclusion: The results suggest that pre-surgical treatment is a key factor influencing the closure rate.

关键词： Tympanoplasty Underlay Method

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水稻香味的遗传

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杂交水稻 1991年第2期6卷 47-48页

作者： E.tsuzuki E.shimokawa 吴京华日本宫崎大学农学院

本研究以尼泊尔香稻品种“Ｂｒｉｍｆｕｌ”与日本非香稻当家品种“Ｋｏｓｈｉｈｉｋａｒｉ”、“Ｎｉｐｐｏｎｂａｒｅ”作亲本杂交。Ｆ２香味对无香味的分离方式是３：１３，表明在两组杂交中有一个香味编码基因和一个编码抑制基因。... 详细信息

本研究以尼泊尔香稻品种“Ｂｒｉｍｆｕｌ”与日本非香稻当家品种“Ｋｏｓｈｉｈｉｋａｒｉ”、“Ｎｉｐｐｏｎｂａｒｅ”作亲本杂交。Ｆ２香味对无香味的分离方式是３：１３，表明在两组杂交中有一个香味编码基因和一个编码抑制基因。这个分离比率由Ｆ３群体的遗传行为进一步证实。

关键词：水稻香味遗传

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Research of Rolling Super Heavy H-Beam from ***

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第七届(2009)中国钢铁年会

作者： yoshiaki Kusaba Corporate Research ＆ Development Laboratories Sumitorno MetalJapan

＜正＞Super Heavy H-beam with 1,000-1,200 mm web-height and 400 mm flange width is difficult to be produced by hot-rolling. The authors researched to develop the new rolling method for H 1000 - 1200×400 mm especially with thick flange from slabs:250 mm×1600 mm by using FEM simulation and model test rolling with special designed grooves of the breakdown mill and universal mills.

关键词： Super Heavy H-beam Groove-rolling Universal Mill-Rolling

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Effectiveness of Somatic Balance Restoration Therapy to Alleviate Pain of Musculoskeletal System

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Health 2017年第10期9卷 1390-1403页

作者： Munehiro Mike Kayo yoshiaki Ohkami Institute of System Design and Management Yokohama Japan

Chronic pain and general physical discomfort are common symptoms among those seeking medical or physiotherapy treatment, as it relates to disorders found in the Human Musculoskeletal System (HMS). Since this system is highly complex and large in scale, clinical pain research has been confounded by many complex factors. The goal of our research is to overcome these obstacles by applying multidisciplinary approaches including systems engineering, traditional oriental techniques, conventional medicine and related sciences. To pursue such an integrated approach this paper examines the therapist-guided exercise for restoring human musculoskeletal balance called the Somatic Balance Restoration Therapy (SBRT). The SBRT is a simple but effective self-exercise therapy with minimal assistance by a trained therapist. This therapy is analyzed by a mechanical engineering method by modeling the human body as a multi-body subject to a static equilibrium condition. In addition, the wording has been rewritten in functional anatomical terms, enabling smooth communication between specialists of three different disciplines: therapy, conventional medicine and systems engineering. Examples will be given to demonstrate an integrated and systematic approach for identifying and remedying malfunctions within the HMS.

关键词： Integrated Medicine Self-Exercise Therapy Musculoskeletal Pain Systems Approach

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