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Optic perineuritis as an initial presentation of ocular toxoplasmosis:a case report

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International Journal of Ophthalmology(English edition) 2022年第12期15卷 2043-2046页

作者： Seung Ah chung chungwoon Kim Jong yoon Lim yoo-ri chung Department of Ophthalmology Ajou University School of MedicineSuwon 16499Republic of Korea The Bright Eye Center Gwangmyeong 14235Republic of Korea

Dear Editor,Ocular toxoplasmosis,caused by Toxoplasma gondii infection,is one of the most common causes of posterior uveitis worldwide[1].It typically manifests as white focal retinitis with overlying vitreous inflammation that results in a chorioretinal scar and associated scotoma[2].However,the diagnosis of ocular toxoplasmosis can be challenging when it presents as an isolated papillitis without other typical signs of retinochoroiditis or vitritis[2].Although optic nerve involvement in ocular toxoplasmosis was present in 5.3%of cases,isolated papillitis was extremely rare(3 eyes out of 926 patients)and was only considered a presumed diagnosis in such cases given the presence of old toxoplasmic retinochoroiditis lesions[3].Few reports have described optic nerve involvement preceding toxoplasmic retinochoroiditis,while perineuritis,an uncommon form of orbital inflammatory disease involving the optic nerve sheath,has not been reported at all[4-5].Herein,we describe a case of ocular toxoplasmosis that initially presented with optic perineuritis followed by typical retinochoroidal *** our knowledge,this is the first case report of ocular toxoplasmosis with perineuritis in an immunocompetent individual.

关键词： ocular diagnosis neuritis

Insights into the pathogenesis of cystoid macular edema: leukostasis and related cytokines

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International Journal of Ophthalmology(English edition) 2019年第7期12卷 1202-1208页

作者： yoo-ri chung Young Ho Kim Seung Yeop Lee Hye-Eun Byeon Kihwang Lee Department of Ophthalmology Ajou University School of Medicine Suwon 16499 Korea Institute of Medical Science Ajou University School of Medicine Suwon 16499 Korea

Cystoid macular edema(CME) is the abnormal collection of intraretinal fluid in the macular region, especially in the inner nuclear and outer plexiform layers. CME leads to severe visual impairment in patients with various retinal diseases, such as diabetic retinopathy, retinal vascular occlusion, choroidal neovascularization, and uveitis. Although various retinal conditions lead to CME, a shared pathogenesis of CME is involved in these diseases. Accordingly, the pathogenesis of CME based on vasogenic mechanisms is first discussed in this review, including vascular hyperpermeability, leukostasis, and inflammation. We then describe cytotoxic mechanisms based on retinal Müller cell dysfunction. This comprehensive review will provide an understanding of the pathogenesis of CME for potential therapeutic strategies.

关键词： cystoid macular edema cytokine leukostasis pathogenesis

Defect Detection Model Using Time Series Data Augmentation and Transformation

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Computers, Materials & Continua 2024年第2期78卷 1713-1730页

作者： Gyu-Il Kim Hyun yoo Han-Jin Cho Kyungyong chung Department of Computer Science Kyonggi UniversitySuwon-si16227Korea Contents Convergence Software Research Institue Kyonggi UniversitySuwon-si16227Korea Department of Energy IT Engineering Far East UniversityEumsung-gun27601Korea Division of AI Computer Science and Engineering Kyonggi UniversitySuwon-si16227Korea

Time-series data provide important information in many fields,and their processing and analysis have been the focus of much ***,detecting anomalies is very difficult due to data imbalance,temporal dependence,and ***,methodologies for data augmentation and conversion of time series data into images for analysis have been *** paper proposes a fault detection model that uses time series data augmentation and transformation to address the problems of data imbalance,temporal dependence,and robustness to *** method of data augmentation is set as the addition of *** involves adding Gaussian noise,with the noise level set to 0.002,to maximize the generalization performance of the *** addition,we use the Markov Transition Field(MTF)method to effectively visualize the dynamic transitions of the data while converting the time series data into *** enables the identification of patterns in time series data and assists in capturing the sequential dependencies of the *** anomaly detection,the PatchCore model is applied to show excellent performance,and the detected anomaly areas are represented as heat *** allows for the detection of anomalies,and by applying an anomaly map to the original image,it is possible to capture the areas where anomalies *** performance evaluation shows that both F1-score and Accuracy are high when time series data is converted to ***,when processed as images rather than as time series data,there was a significant reduction in both the size of the data and the training *** proposed method can provide an important springboard for research in the field of anomaly detection using time series ***,it helps solve problems such as analyzing complex patterns in data lightweight.

关键词： Defect detection time series deep learning data augmentation data transformation

Galectin 3-binding protein(LGALS3BP)depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1(TGF-β1)availability and inhibits hepatocarcinogenesis

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Cancer Communications 2024年第10期44卷 1106-1129页

作者： Dae-Hwan Kim Minjeong Sung Myong-Suk Park Eun-Gene Sun Sumin yoon Kyung Hyun yoo Kamalakannan Radhakrishnan Sung Yun Jung Woo-Kyun Bae Sang-Hee Cho Ik-Joo chung Department of Internal Medicine Division of Hematology and OncologyChonnam National University Medical SchoolHwasunSouth Korea Department of Internal Medicine Division of Hematology and OncologyChonnam National University Hwasun HospitalHwasunSouth Korea Combinatorial Tumor Immunotherapy MRC Center Chonnam National University Medical SchoolHwasunSouth Korea National Immunotherapy Innovation Center HwasunSouth Korea BioMedical Sciences Graduate Program Chonnam National UniversityHwasunSouth Korea Department of Biological Science SookmyungWomen’s UniversitySeoulSouth Korea Clinical Vaccine R&D Center Chonnam National UniversityHwasunSouth Korea Department of Biochemistry and Molecular Pharmacology Baylor College of MedicineHoustonTexasUSA

Background:Increased Galectin 3-binding protein(LGALS3BP)serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma(HCC).Considering the crucial role of transforming growth factor-β1(TGF-β1)in the emergence of these diseases,the present study tested the hypothesis that LGALS3BP regulates the TGF-β1 signaling ***:The expression levels of LGALS3BP and TGFB1 were analyzed in patients with metabolic dysfunction-associated steatohepatitis(MASH)and *** omics techniques,such as RNA-sequencing,transposaseaccessible chromatin-sequencing assay,and liquid chromatography-tandem mass spectrometry proteomics,were used to identify the regulatory mechanisms for the LGALS3BP-TGF-β1 *** effects of altered TGF-β1 signaling by LGALS3BP were investigated in conditional LGALS3BP-knockin and LGALS3BP-knockout ***:In patients with MASH and HCC,the levels of LGALS3BP and TGFB1 exhibited positive *** of LGALS3BP by the inflammatory cytokine interferonαin HCC cells or ectopic overexpression of LGALS3BP in hepatocytes promoted the expression levels of *** fibrosis was observed in the livers of hepatocyte-specific LGALS3BP-knockin mice,with increased TGFB1 ***3BP directly bound to and assembled integrinαV,an integral mediator required for releasing active TGF-β1 from extracellular latent complex with the rearranged F-actin *** released TGF-β1 activated JunB transcription factor,which in turn promoted the TGF-β1 positive feedback ***3BP deletion in the hepatocytes downregulated TGF-β1 signaling and CCl4 induced ***,LGALS3BP depletion hindered hepatocarcinogenesis by limiting the availability of fibrogenic TGF-β***:LGALS3BP plays a crucial role in hepatic fibrosis and carcinogenesis by controlling the TGF-β1 signaling pathway,making it a promising therapeutic target in TGF-β1-related diseases.

关键词： F-actin FAK hepatic carcinogenesis IntegrinαV Interferonα JunB LGALS3BP metabolic dysfuntion-associated steatohepatitis tensile force TGF-β1

N,P co-doped 3D porous carbon with self-assembled morphological control via template-free method for potassiumion battery anodes

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Rare Metals 2024年第9期43卷 4243-4252页

作者： Jeehoon Yu Dae Kyom Kim Hong Geun Oh Seung-Keun Park Youngjae yoo Department of Advanced Materials Engineering Chung-Ang UniversityAnseong-si 17546Republic of Korea

The larger ionic radius of potassium ions than that of lithium ions significantly limits the accomplishment of rapid diffusion kinetics in graphite electrodes for potassium-ion batteries(PIBs),resulting in comparatively poor rate performance and cycle ***,we report a high-rate performance and cycling stability amorphous carbon electrode achieved through nitrogen and phosphorous *** as-prepared N,P co-doped carbon electrodes have distinct 3D structures with large surface areas,hierarchical pore architectures,and increased interlayer spaces resulting from the direct pyrolysis of supramolecular self-assembled aggregates without *** obtained electrode N3P1 exhibits a reversible specific capacity of 258 m Ah·g^(-1)at a current density of 0.1A·g^(-1)and a good long-term cycle performance(96.1%capacity retention after 800 cycles at 0.5 A·g^(-1)).Kinetic investigations show that the N3P1 electrode with the welldeveloped porous structure and large number of surface defects exhibits capacitive-driven behavior at all scan rates,which may be attributed by N and P ***-situ transmission electron microscopy analyses in the fully discharged and charged states demonstrate structural stability and reversibility owing to the expanded interlayer *** suggested synthesis approach is simple and effective for producing heteroatom-doped carbon materials for PIBs and other advanced electrochemical energy storage materials.

关键词： Amorphous carbons 3D porous structures Nitrogen and phosphorous co-doping Potassium-ion batteries

Deep Learning-Based Action Classification Using One-Shot Object Detection

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Computers, Materials & Continua 2023年第8期76卷 1343-1359页

作者： Hyun yoo Seo-El Lee Kyungyong chung Contents Convergence Software Research Institute Kyonggi UniversitySuwon-si16227Korea Department of Public Safety Bigdata Kyonggi UniversitySuwon-si16227Korea Division of Computer Science and Engineering Kyonggi UniversitySuwon-si16227Korea

Deep learning-based action classification technology has been applied to various fields,such as social safety,medical services,and *** an action on a practical level requires tracking multiple human bodies in an image in real-time and simultaneously classifying their *** are various related studies on the real-time classification of actions in an ***,existing deep learning-based action classification models have prolonged response speeds,so there is a limit to real-time *** addition,it has low accuracy of action of each object ifmultiple objects appear in the ***,it needs to be improved since it has a memory overhead in processing image *** learning-based action classification using one-shot object detection is proposed to overcome the limitations of multiframe-based analysis *** proposed method uses a one-shot object detection model and a multi-object tracking algorithm to detect and track multiple objects in the ***,a deep learning-based pattern classification model is used to classify the body action of the object in the image by reducing the data for each object to an action *** to the existing studies,the constructed model shows higher accuracy of 74.95%,and in terms of speed,it offered better performance than the current studies at 0.234 s per *** proposed model makes it possible to classify some actions only through action vector learning without additional image learning because of the vector learning feature of the posterior neural ***,it is expected to contribute significantly to commercializing realistic streaming data analysis technologies,such as CCTV.

关键词： Human action classification artificial intelligence deep neural network pattern analysis video analysis

Management of obstructive colon cancer:Current status,obstacles,and future directions

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World Journal of Gastrointestinal Oncology 2021年第12期13卷 1850-1862页

作者： ri-Na yoo Hyeon-Min Cho Bong-Hyeon Kye Division of Colorectal Surgery Department of SurgerySt.Vincent’s HospitalThe Catholic University of KoreaSuwon 442-723South Korea

Approximately 10%–18%of patients with colon cancer present with obstruction at the initial *** active screening efforts,the incidence of obstructive colon cancer remains ***,emergency surgery has been indicated to treat patients with obstructive colon ***,compared to patients undergoing elective surgery,the morbidity and mortality rates of patients requiring emergency surgery for obstructive colon cancer are *** the advancement of colonoscopic techniques and equipment,a self-expandable metal stent(SEMS)was introduced to relieve obstructive symptoms,allowing the patient’s general condition to be restored and for them undergo elective *** the use of SEMS placement is growing,controversies about its application in potentially curable diseases have been *** this review,the short-and longterm outcomes of different treatment strategies,particularly emergency surgery vs SEMS placement followed by elective surgery in resectable,locally advanced obstructive colon cancer,are described based on the location of the obstructive cancer *** regarding each treatment strategy are *** overcome current obstacles,a potential diagnostic method using circulating tumor DNA and further research directions incorporating neoadjuvant chemotherapy are introduced.

关键词： Colonic neoplasms Self-expandable metallic stents Intestinal obstruction Survival rate Morbidity Mortality

Self‑Powered Airflow Sensor Based on Energy Harvesting of Ventilation Air in Buildings

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Advanced Fiber Materials 2023年第5期5卷 1788-1798页

作者： Moon Hyun chung Seunghwan yoo Woo‑Nam Jung Hakgeun Jeong Kyung‑Hwa yoo Department of Physics Yonsei University50 Yonsei‑RoSeodaemun‑GuSeoul 03722Republic of Korea Energy ICT Convergence Research Department Energy Efficiency Research DivisionKorea Institute of Energy Research152 Gajeong‑RoYuseong‑GuDaejeon 34129Republic of Korea Advanced Combustion Power Lab Energy Efficiency Research DivisionKorea Institute of Energy Research152Gajeong‑RoYuseong‑GuDaejeon 34129Republic of Korea Department of Mechanical Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak‑RoYuseongDaejeon 34141Republic of Korea

Heating,ventilation,and air conditioning(HVAC)systems account for one-third of the total energy consumption in office *** use of airflow measurements to control the operation of HVAC systems can reduce energy consumption;thus,a sensor capable of monitoring airflow in a duct system is *** nanogenerators(TENGs)can be utilized as self-powered sensors in airflow-driven TENGs(ATENGs)as self-powered *** employing ferroelectric materials and surface modifications,the surface charges of TENGs can be *** this study,fibrous-mat TENGs were prepared using ferroelectric materials consisting of poly(vinylidene fluoride-co-trifluoroethylene)(PVDF-TrFE)and polyamide 11(nylon-11).And these materials were subsequently ***(3,4-ethylenedioxythiophene):poly(styrenesulfonate)was added to PVDF-TrFE to enhance the ferroelectric crystalline phase.X-ray diffraction analysis revealed that this incorporation affects theβ*** addition,the surface of nylon-11 was modified using the electrospray technique for post-treatment,thereby improving the interfacial adhesion between the *** materials were then utilized in fibrous-mat ATENGs(FM-ATENGs)to demonstrate their practical *** FM-ATENGs can be effectively used in an Arduino airflowcheck sensor,showcasing their potential for application in HVAC systems,to enhance airflow control and energy efficiency.

关键词： HVAC Airflow-driven triboelectric nanogenerator Building energy harvesting Fibrous mat Airflow sensor

Electrical characteristics and detailed interfacial structures of Ag/Ni metallization on polycrystalline thermoelectric SnSe

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Journal of Materials Science & Technology 2019年第5期35卷 711-718页

作者： Yeongseon Kim Younghwan Jin Giwan yoon In chung Hana yoon chung-Yul yoo Sang Hyun Park Separation and Conversion Materials Laboratory Korea Institute of Energy Research 152 Gajeong-ro Yuseong-gu Daejeon 34129 Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and Technology 291 Daehak-ro Yuseong-gu Daejeon 34142 Republic of Korea Department of Physics Chungnam National University 99 Daehak-ro Yuseong-gu Daejeon 34134 Republic of Korea School of Chemical and Biological Engineering Seoul National University 1 Gwanak-ro Gwanak-gu Seoul 08826 Republic of Korea

SnSe is a promising thermoelectric material with a high figure of merit in single crystal form, which has stimulated continuous research on polycrystalline SnSe. In this study, we investigated a metallization techniques for polycrystalline SnSe to achieve highly efficient and practical SnSe thermoelectric modules. The Ag/Ni metallization layers were formed on pristine polycrystalline SnSe using various deposition technique: sputter coating Ni, powder Niand foil Ni by spark plasma sintering. Structural analysis demonstrated that the microstructure and con tact resistance could be different according to the metallization process, despite using the same metals. The Ag/Ni metallization layer using foil Ni acted as an effective diffusion barrier and minimized electrical contact resistance (2.3×10^-4Ωcm^2). A power loss in the thermoelectric module of only 5% was demonstrated using finite element simulation.

关键词： Thermoelectric Metallization Electric contact material Interface microstructure SnSe