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Dynamic Characteristics Analysis of Ice-Adhesion Transmission Tower-Line System under Effect of Wind-Induced Ice Shedding

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Computer Modeling in Engineering & Sciences 2020年第11期125卷 647-670页

作者： yongping yu Lihui Chen JuanjuanWang Guoji Liu College of Construction Engineering Jilin UniversityChangchun130021China College of Physics Jilin UniversityChangchun130012China

The tower line system will be in an unsafe status due to uniform or uneven fall of ice coating which is attached to the surface of tower and *** fall of ice could be caused by wind action or thermal *** order to study the dynamic characteristics of the self-failure of the transmission line under the action of dynamicwind load,a finite elementmodel of the two-span transmission tower line system was *** birth and death element methods are used to simulate the icing and shedding of the *** failure strength is the shedding criterion for ice *** fluctuating wind speed time history of the tower line systemis first simulated,and then the fluctuating wind and the average wind are superimposed to generate the instantaneous wind speed and converted into wind *** dynamic response of the transmission tower line systemunder iced coupling with different wind speeds and different thicknesses of ice coating was *** is the first attempt that the coupling dynamic response of the icing shedding and wind load for the transmission tower-line system is discussed in this *** addition,the dynamic characteristics of wind are *** particular,the limiting mechanical conditions are *** to the simulation results,it is found:because of the ice shedding,the stress of the conductor changes obviously in the first 20 seconds,and the ground wire changes sharply in the first two seconds;the icing of the conductor(ground)wire is gradually deicing under the action of wind vibration;the displacement of tower top increases with the increase of wind speed and icing thickness.

关键词： Tower line system fluctuating wind ice shedding dynamic response wind-induced ice shedding

Analysis and prognosis of tropical cyclone genesis over the western North Pacific on the background of global warming

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Acta Oceanologica Sinica 2007年第1期26卷 23-34页

作者： LI yongping WANG Xiaofeng yu Runling QIN Zenghao Open Laboratory for Typhoon Research Shanghai Typhoon Institute China Meteorological Administration Shanghai 200030

As revealed by the observational study, there are more tropical cyclones generated over the western North Pacific from the early 1950s to the early 1970s in the 20th century and less tropical cyclones from the mid-1970s to the present. The decadal change of ＂tropical cyclones activities are closely related to the decadal changes of atmospheric general circulation in the troposphere, which provide favorable or unfavorable conditions for the formation of tropical cyclone. Furthermore, based on the simulation of corresponding atmospheric general circulation from a coupled climate model under the schemes of Intergovemmental Panel on Climate Change （IPCC）,special report on emission scenarios （SRES） A2 and B2 emissions scenarios an outlook on the tropical cyclone frequency generated over the western North Pacific in the coming half century is presented. It is indicated that in response to the global climate change the general circulation of atmosphere would become unfavorable for the formation of tropical cyclone as a whole and the frequency of tropical cyclones formation would likely decrease by 5% within the next half century, although more tropical cyclones would appear during a short period in it.

关键词： IPCC SRES A2 and B2 general circulation anomaly frequency of tropical cyclone

Closed Solution for Initial Post-Buckling Behavior Analysis of a Composite Beam with Shear Deformation Effect

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Computer Modeling in Engineering & Sciences 2020年第4期123卷 185-200页

作者： yongping yu Lihui Chen Shaopeng Zheng Baihui Zeng Weipeng Sun College of Construction Engineering Jilin UniversityChangchun130021China School of Mathematics Jilin UniversityChangchun130012China

This paper is focused on the post-buckling behavior of the fixed laminated composite beams with effects of axial compression force and the shear *** analytical solutions are established for the original control equations(that is not simplified)by applying the Maclaurin series expansion,Chebyshev polynomials,the harmonic balance method and the Newton’s *** validity of the present method is verified via comparing the analytical approximate solutions with the numerical ones which are obtained by the shooting *** present third analytical approximate solutions can give excellent agreement with the numerical solutions for a wide range of the deformation ***’s more,the effect of shear deformation on the post-bucking configuration of the sandwich beam is also *** can be found that the shear angle has a great influence on the post-buckling load of composite ***,the model simplifying the shear formation term as small quantity is not accurate for the case of sandwich beam with soft core.

关键词： Analytical solution post-buckling sandwich beam harmonic method

Rapid alkenylation of quinoxalin-2(1H)-ones enabled by the sequential Mannich-type reaction and solar photocatalysis

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Chinese Chemical Letters 2021年第11期32卷 3627-3631页

作者： Lin Huang Jun Xu Lei He Chenfeng Liang Yani Ouyang yongping yu Wanmei Li Pengfei Zhang College of Material Chemistry and Chemical EngineeringHangzhou Normal UniversityHangzhou 311121China College of Pharmaceutical Science Zhejiang UniversityHangzhou 310058China

Herein,a rapid alkenylation of quinoxalin-2(1H)-ones enabled by a combination of Mannich-type reaction and solar photocatalysis is demonstrated.A wide range of functional groups are compatible,affording the corresponding products in moderate-to-good *** experiments illustrate that the in situ generated^(1)O_(2)plays a central role in this *** green and efficient strategy provides a practical solution for the synthesis of potentially bioactive compounds that containing a 3,4-dihydroquinoxalin-2(1H)-one structure.

关键词： Alkenylation Quinoxalin-2(^(1)H)-ones Methyl ketones Mannich-type reaction Solar photocatalysis

Damage Identification under Incomplete Mode Shape Data Using Optimization Technique Based on Generalized Flexibility Matrix

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Journal of Applied Mathematics and Physics 2023年第12期11卷 3887-3901页

作者： Qianhui Gao Zhu Li yongping yu Shaopeng Zheng College of Construction Engineering Jilin University Changchun China

A generalized flexibility–based objective function utilized for structure damage identification is constructed for solving the constrained nonlinear least squares optimized problem. To begin with, the generalized flexibility matrix (GFM) proposed to solve the damage identification problem is recalled and a modal expansion method is introduced. Next, the objective function for iterative optimization process based on the GFM is formulated, and the Trust-Region algorithm is utilized to obtain the solution of the optimization problem for multiple damage cases. And then for computing the objective function gradient, the sensitivity analysis regarding design variables is derived. In addition, due to the spatial incompleteness, the influence of stiffness reduction and incomplete modal measurement data is discussed by means of two numerical examples with several damage cases. Finally, based on the computational results, it is evident that the presented approach provides good validity and reliability for the large and complicated engineering structures.

关键词： Generalized Flexibility Matrix Damage Identification Constrained Nonlinear Least Squares Trust-Region Algorithm Sensitivity Analysis Incomplete Modal Data

Facile,eco-friendly,catalyst-free synthesis of polyfunctionalized 2-aminopyrroles

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Facile,eco-friendly,catalyst-free synthesis of polyfunctiona...

Design,Synthesis and Structure-Activity Study of Novel Endomorphins Analogues

2012长三角药物化学研讨会

作者： Wanwan yu Wei Huang yongping yu

Pyrroles are important heterocycles that display various biological activities and are widely used in both organic chemistry and material *** the essential component of pyrroles, aminopyrroles have been found to show valuable and diverse biological *** the 2-aminopyrrole fragments are part of many bioactive compounds and have been used as precursors for the synthesis of purine analogues including pyrrolopyrimidines,pyrrolotriazines and *** this regard,the excellent methodologies constructing 2-aminopyrrole rings are needed.

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Design,Synthesis and Structure-Activity Study of Novel Endom...

Synthesis and Study of VATP inhibitors as Potential drugs for the Treatment of Osteoporosis

2012长三角药物化学研讨会

作者： Miao Hu Jiaan Shao yongping yu Institute of Materia Medica College of Pharmaceutical SciencesZhejiang University

Opioid receptors are members of the superfamily of G-protein coupled receptors(GPCR),which have three subtypes:theμopioid receptor(MOR),the 8 opioid receptor(DOR),and the k opioid receptor(KOR). These receptors mediate the actions of opiate alkaloids and opioid peptides and take part in a variety of biological processes,including pain perception and modulation.A major goal in opioid peptide research is

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Synthesis and Study of VATP inhibitors as Potential drugs fo...

ACSL5,a prognostic factor in acute myeloid leukemia,modulates the activity of Wnt/β-catenin signaling by palmitoylation modification

2012长三角药物化学研讨会

作者： Zhanying Shao Hangcheng Ni yongping yu College of Pharmaceutical Sciences Zhejiang University

Low bone density and osteoporosis represent a major health threat for millions of people worldwide. Imidazolopyridine derivatives were reported to show inhibition against various matrix metalloproteinase (MMPs) at micro molar *** are a small family of zinc and calcium dependent proteases that are implicated in many disease *** production of excess MMPs leads to the degradation of the extracellular matrix in connective tissue,which leads to disease symptoms including bone matrix

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Frontiers of Medicine 2023年第4期17卷 685-698页

作者： Wenle Ye Jinghan Wang Jiansong Huang Xiao He Zhixin Ma Xia Li Xin Huang Fenglin Li Shujuan Huang Jiajia Pan Jingrui Jin Qing Ling yungui Wang yongping yu Jie Sun Jie Jin Department of Hematology The First Affiliated HospitalZhejiang University College of MedicineHangzhou 310003China Key Laboratory of Hematopoietic Malignancies Diagnosis and TreatmentHangzhou 310009China Research Centre Centre hospitalier de l’Universitéde Montréal(CRCHUM)MontrealQuebec H2L 4M1Canada Women’s Hospital School of MedicineZhejiang UniversityHangzhou 310006China Zhejiang Province Key Laboratory of Anti-Cancer Drug Research College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Cancer Center Zhejiang UniversityHangzhou 310058China

Acyl-CoA synthetase long chain family member 5(ACSL5),is a member of the acyl-CoA synthetases(ACSs)family that activates long chain fatty acids by catalyzing the synthesis of fatty *** dysregulation of ACSL5 has been reported in some cancers,such as glioma and colon ***,little is known about the role of ACSL5 in acute myeloid leukemia(AML).We found that the expression of ACSL5 was higher in bone marrow cells from AML patients compared with that from healthy ***5 level could serve as an independent prognostic predictor of the overall survival of AML *** AML cells,the ACSL5 knockdown inhibited cell growth both in vitro and in ***,the knockdown of ACSL5 suppressed the activation of the Wnt/β-catenin pathway by suppressing the palmitoylation modification of ***,triacsin c,a pan-ACS family inhibitor,inhibited cell growth and robustly induced cell apoptosis when combined with ABT-199,the FDA approved BCL-2 inhibitor for AML *** results indicate that ACSL5 is a potential prognosis marker for AML and a promising pharmacological target for the treatment of molecularly stratified AML.

关键词： acute myeloid leukemia acyl-CoA synthetase long chain family member 5 Wnt3a palmitoylation ABT-199