检索结果-南通市图书馆

One-year direct and indirect costs of ischaemic stroke in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2024年第4期9卷 380-389,I0032-I0043页

作者： Wei Lv Anxin wang Qianyi wang Ruimin wang Qin Xu Shuqing Wu Yi Han Yong Jiang Jinxi Lin Jing Jing Hao Li yongjun wang Xia Meng Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina School of Basic Medical Science Capital Medical UniversityBeijingChina Department of Cardiology Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityGuangzhouChina Health Economic Research Institute Sun Yat-Sen UniversityGuangzhouChina

Background This is the first real-world study to estimate the direct costs and indirect costs of first-ever ischaemic stroke with 1-year follow-up in China,based on a nationally representative *** Patients were chosen from 20 geographically diverse sites from the nationally representative database China National Stroke Registry-III(CNSR-III).The inclusion criteria were surviving patients who were hospitalised with first-ever ischaemic stroke from February 2017 to February 2018(the index event);aged 18–80 during the index event;no history of other stroke *** primary endpoints were direct medical costs,direct non-medical costs,indirect costs and total cost(ie,the sum of all cost components).Patient characteristics and clinical data were extracted from ***-related in-hospital direct medical costs were collected from hospital electronic medical *** patient survey collected data related to out-of-hospital direct medical costs,direct non-medical costs and indirect *** secondary objective was to explore clinical factors associated with cost outcomes through univariate analysis and multiple *** The study enrolled 520 *** total cost was 57567.48 CNY,with 26612.67 CNY direct medical costs,2787.56 CNY direct non-medical costs and 28167.25 CNY indirect *** analysis showed that longer lengths of stay during the index event,higher National Institutes of Health Stroke Scale(NIHSS)and modified Rankin Scale scores were associated with higher costs in all ***,EuroQol 5 Dimension utility scores were associated with decreased costs except direct non-medical *** regressions showed that higher admission NIHSS scores were independently associated with higher direct medical costs,indirect costs and total *** 3-month utilities were associated with lower total *** This real-world study showed substantial 1-year economic burden following first-ever ischaemic stroke

关键词： indirect costs Dimension

Impact of COVID-2019 on stroke services in China: survey from the Chinese Stroke Association

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2020年第4期5卷 323-330页

作者： Xia wang Menglu Ouyang Cheryl Carcel Chen Chen Lingli Sun Jie Yang Yao Zhang Guofang Chen Shoujiang You yongjun Cao Lu Ma Xin Hu Yi Sui Craig Anderson Lili Song yongjun wang David wang The George Institute for Global Health Faculty of MedicineUniversity of New South WalesSydneyNew South WalesAustralia Department of Neurology Shanghai East HospitalShanghaiShanghaiChina Stroke Division The George Institute China at Peking University Health Science CentreBeijingPR ChinaShanghaiChina Department of Neurology The First Affiliated Hospital of Chengdu Medical CollegeChengduChina Department of Neurology Shenyang Brain HospitalShenyang Medical CollegeShenyangChina Department of Neurology Xuzhou Central HospitalXuzhouJiangsuChina Department of Neurology The Second Affiliated Hospital of Soochow UniversitySuzhouJiangsuChina Department of Neurosurgery West China Hospital of MedicineChengduSichuanChina Department of Neurology Royal Prince Alfred HospitalSydneyNSWAustralia Department of Neurology China National Clinical Research Center for Neurological DiseaseBeijingChina Department of Neurology Tiantan Clinical Trial and Research Center for StrokeBeijingChina Neurovascular Division Department of NeurologyBarrow Neurological InstituteSt.Joseph's Hospital and Medical CenterPhoenixArizonaUSA

Background The COVID-19 pandemic and physical distancing guidelines have compelled stroke practices worldwide to reshape their delivery of care *** aimed to illustrate how the stroke services were interrupted during the pandemic in *** A 61-item questionnaire designed on Wenjuanxing Form was completed by doctors or nurses who were involved in treating patients with stroke from 1 February to 31 March *** A total of 415 respondents completed the online survey after informed consent was *** the respondents,37.8%,35.2%and 27.0%were from mild,moderate and severe epidemic areas,***,the proportion of severe impact(reduction>50%)on the admission of transient ischaemic stroke,acute ischaemic stroke(AIS)and intracerebral haemorrhage(ICH)was 45.0%,32.0%and 27.5%,*** numbers were 36.9%,27.9%and 22.3%;36.5%,22.1%and 22.6%;and 66.4%,47.5%and 41.1%in mild,moderate and severe epidemic areas,respectively(all p50%),as reported by 54.4%of the respondents,while thrombectomy was 39.3%.These were 44.4%,26.3%;44.2%,39.4%;and 78.2%,56.5%,in mild,moderate and severe epidemic areas,respectively(all p<0.0001).For patients with acute ICH,39.8%reported the impact was severe or moderate for those eligible for surgery who had *** numbers were 27.4%,39.0%and 58.1%in mild,moderate and severe epidemic areas,*** staff resources,about 20%(overall)to 55%(severe epidemic)of the respondents reported moderate or severe impact on the on-duty doctors and *** We found a significant reduction of admission for all types of patients with stroke during the *** were less likely to receive appropriate care,for example,thrombolysis/thrombectomy,after being admitted to the *** service in severe COVID-19 epidemic areas,for example,Wuhan,was much more severely impacted compared with other regions in China

关键词： nurse admitted services

The Chinese Stroke Association scientific statement:intravenous thrombolysis in acute ischaemic stroke

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2017年第3期2卷 147-159页

作者： Qiang Dong Yi Dong Liping Liu Anding Xu Yusheng Zhang Huaguang Zheng yongjun wang 无 Department of Neurology Huashan Hospital affiliated to Fudan UniversityShanghai ShiChina Department of Neurology Beijing Tiantan Hospital affiliated to Capital Medical UniversityBeijingChina Department of Neurology and Stroke Center First Affiliated HospitalJinan UniversityGuangzhou ShiChina On behalf of the CSA Scientific Statement on Intravenous Thrombolysis in Acute Ischemic Stroke Writing Group

The most effective medical treatment for acute ischaemic stroke(AIS)is to offer intravenous thrombolysis during the ultra-early period of time after the *** based on the Consensus of Chinese Experts on Intravenous Thrombolysis for AIS in 2012 and 2014 Chinese Guidelines on the Diagnosis and Treatment of AIS,the rate of thrombolysis for AIS in China remained around 2.4%,and the rate of intravenous tissue plasminogen activator usage was only about 1.6%in real *** indication of thrombolysis for AIS has been expanded,and contraindications have been reduced with recently published *** order to facilitate the standardisation of treating AIS,improve the rate of thrombolysis and benefit patients who had a stroke,Chinese Stroke Association has organised and developed this scientific statement.

关键词： thrombolysis intravenous acute

Acute Ischaemic Stroke Cooperation Group of Endovascular Treatment (ANGEL) registry: study protocol for a prospective, multicentre registry in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2019年第1期4卷 57-60页

作者： Xiaochuan Huo Ning Ma Dapeng Mo Feng Gao Ming Yang Yilong wang yongjun wang Zhongrong Miao ANGEL investigators Neurointervention Center Beijing Tiantan HospitalBeijingChina Department of Interventional Neurology Beijing Tiantan HospitalBeijingChina Neurology Beijing Tiantan HospitalBeijingChina

Background and purpose Endovascular treatment could improve functional outcomes and reduce mortality in patients with intracranial large artery occlusion. This registry aims to evaluate the endovascular treatment delivery and to improve endovascular treatment algorithm in clinical practice for patients with stroke in China. Methods and analysis This multicentric, nationwide, prospective registry plans to include 20 stroke centres and recruit 900 consecutive AIS patients with large- artery occlusion under endovascular treatment. This registry will enrol acute large vessel occlusion patients suitable for endovascular treatment and the inclusion and exclusion criteria. In this study, 90 days functional independence (modified Rankin Scale score ≤2) is the primary efficacy endpoint. The procedural efficacy endpoint of this registry is target artery recanalisation defined by modified Thrombolysis in Cerebral Infarction score 2b or 3 after endovascular therapy. Symptomatic intracranial haemorrhage with 24±3 hours after the procedure is the primary safety endpoint of this registry. Ethics and dissemination Beijing Tiantan Hospital’s Ethics committee and all other participating centres approved the protocol and data collection of Acute Ischaemic Stroke Cooperation Group of Endovascular Treatment registry. Each participant or representative had a written informed consent.

关键词： prospective centre registry

Approaches to global stroke care during the COVID-19 pandemic

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2020年第2期5卷 107-109页

作者： Liping Liu David wang Michael Brainin Mitchell S V Elkind Enrique Leira yongjun wang China National Clinical Research Center for Neurological Diseases BeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Neurovascular Division Department of NeurologyBarrow Neurological InstitutePhoenixArizonaUSA Department of Clinical Neurosciences and Preventive Medicine Danube University KremsKremsAustria Department of Neurology Vagelos College of Physicians and SurgeonColumbia UniversityNew YorkNew YorkUSA Department of Epidemiology Mailman School of Public HealthColumbia UniversityNew YorkNew YorkUSA Departments of Neurology and Neurosurgery The University of Iowa Roy J and Lucille A Carver College of MedicineIowa CityIowaUSA Department of Epidemiology The University of Iowa College of Public HealthIowa CityIowaUSA

Since the outbreak of coronavirus disease 2019(COVID-19),the healthcare system of the world has been overwhelmed by this *** most recent statistic showed that there are now over 3 million people infected and over 2590... 详细信息

关键词： infected statistic COV

GRP per capita and hospital characteristics associated with intravenous tissue plasminogen activator adherence rate:evidence from the Chinese Stroke Center Alliance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2021年第3期6卷 337-343,I0001-I0005页

作者： Suxi Zheng Tian Jie Lyu Zixiao Li Hongqiu Gu Xin Yang Chunjuan wang Hao Li Yong Jiang Haipeng Shen yongjun wang Innvotion and Information Management HKU Business SchoolThe University of Hong KongHong KongChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Shenzhen Institute of Research and Innovation The University of Hong KongShenzhenChina

Background Timely delivery of intravenous tissue plasminogen activator(IV-rt PA)is pivotal to eligible patients who had a stroke while achieving higher rates of IV-rt PA has been *** paper focuses on investigating influential factors associated with the administration of IV-rt PA,primarily per capita gross regional product(GRP)and healthcare system *** The study included 980 hospitals in the Chinese Stroke Center Alliance where 158003 patients who had an acute ischaemic stroke received IV-rt PA between August 2015 and August *** adherence rate to IV-rt PA within 4.5 hours time window in each hospital was the primary *** factors were grouped into two categories:macroeconomic status and hospital *** outcome was analysed using multivariable linear *** GRP per capita(β=2.37,p<0.001),hospital stroke centre certification(β=3.77,p<0.001),number of neurologists(β=0.12,p<0.001),existence of emergency services for neurological treatment(β=7.43,p=0.014),presence of emergency department(β=10.03,p=0.019)and cooperating with emergency centre(β=4.65,p=0.029)were significantly positively associated with the adherence rate to IV-rt *** Higher GRP per capita,affluent neurological personnel,well-equipped emergency services for neurological treatment and routine cooperation with the emergency centre were important for enhancing the adherence rate to IV-rt PA among patients who had an acute ischaemic stroke in China.

关键词： intravenous routine Alliance

Management characteristics and prognosis after stroke in China:findings from a large nationwide stroke registry

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2021年第1期6卷 1-9页

作者： Haiqiang Qin Yiping Chen Gaifen Liu Iain Turnbull Runhua Zhang Zixiao Li Yilong wang Liping Liu Xingquan Zhao Zhengming Chen yongjun wang Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina Center of Stroke Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease BeijingChina Medical Research Council Population Health Research Unit Nuffield Department of Population HealthUniversity of OxfordOxfordUK Clinical Trial Service Unit&Epidemiological Studies Unit Nuffield Department of Population HealthUniversity of OxfordOxfordUK

Background and purpose There is limited nationwide evidence about the standard management characteristics of stroke types and prognosis in *** study aimed to assess clinical characteristics,in-hospital and after-discharge management characteristics and prognosis for stroke types in *** A nationwide registry recruited 14244 imaging-confirmed first-ever incident strokes from 132 hospitals across 31 provinces of China during 2007-2008,recording presenting characteristics,diagnostic procedures and in-hospital *** hospital discharge,patients were followed up for 6 *** statistical methods were used to examine the patterns of management and *** Overall,68.7%,26.9%and 4.4%were ischaemic stroke(IS),intracerebral haemorrhage(ICH),and subarachnoid haemorrhage(SAH),*** 20%were managed in a dedicated stroke *** IS,1.3%received thrombolysis within 3 hours after symptom onset,whereas the proportions of receiving in-hospital antiplatelet therapy,neuroprotective agents and traditional Chinese medicines(TCM)were 88.4%,69.7%and 70.6%,*** ICH,63.3%and 36.3%received neuroprotective agents and TCM in hospital,*** discharge,70.7%and 38.0%of the patients with IS were given antiplatelet and statin therapies,respectively,decreasing to 64.8%and 23.9%,respectively,at 6 ***-hospital mortality was 3.2%,9.3%and 10.1%for IS,ICH and SAH,respectively,with a further 8.6%,18.2%and 22.0%,respectively,died by 6 ***,in-hospital recurrence rate was 2.6%,1.9%and 7.2%for IS,ICH and SAH,respectively,with a further 8.0%,5.1%and 7.5%,respectively,recurred by 6 *** In China,the mortality rate of stroke is lower than that reported from west populations,though most strokes are not managed in specialised stroke *** is widespread use of some unproven therapies but limited proven treatments,especially after discharge,leading to unnecessary recurrent risks.

关键词： protective prognosis mortality

Low LDL-C level and intracranial haemorrhage risk after ischaemic stroke:a prospective cohort study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2023年第2期8卷 127-133页

作者： Jie Xu Zimo Chen Meng wang Jinglin Mo Jing Jing Gulbahram Yalkun Liye Dai Xia Meng Hao Li Zixiao Li yongjun wang Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingFengtaiChina China National Clinical Research Center for Neurological Diseases BeijingChina

Background and purpose The Treat Stroke to Target trial has confirmed the benefit of targeting low-density lipoprotein cholesterol(LDL-C)of<1.8 mmol/L in patients who had an ischaemic stroke(IS).However,haemorrhagic risk brought by this target level(<1.8 mmol/L)or even lower level(<1.4 mmol/L)of LDL-C should also be *** this study,we aimed to demonstrate whether low LDL-C could increase the intracranial haemorrhage risk following *** Patients who had an IS from China Stroke Center Alliance programme with complete baseline information were prospectively enrolled.793572 patients who had an IS were categorised into 6 groups according to LDL-C level(<1.40 mmol/L,1.40-1.79 mmol/L,1.80-2.59 mmol/L,2.60-2.99 mmol/L,3.00-4.89 mmol/L,≥4.90 mmol/L).The study outcome was defined as intracranial haemorrhage identified during *** regression model was used to examine the association between different LDL-C levels and risk of intracranial *** Compared with patients of LDL-C=1.80-2.59 mmol/L,both subgroups of LDL-C<1.40 mmol/L and LDL-C=1.40-1.79 mmol/L showed significantly higher risk of intracranial haemorrhage(OR=1.26,95%CI=1.18 to 1.35;OR=1.22,95%CI=1.14 to 1.30,respectively).Interaction effect was found to exist between the subgroups of intravenous thrombolytic therapy(p=0.04),rather than the subgroups of age,sex and body mass ***,the sensitivity analyses indicated that even patients who had an IS with minor stroke still suffered from the increased intracranial haemorrhage risk related to low LDL-C *** Among patients who had an IS,the low LDL-C level(<1.4 mmol/L or<1.8 mmol/L)at baseline is associated with increased risk of intracranial haemorrhage during acute *** actively lowering LDL-C level for patients who had an IS,clinicians should also concern about the haemorrhagic risk associated with low LDL-C level.

关键词： intracranial prospective cholesterol

Association between Life’s Essential 8 and Cerebral Small Vessel Disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2024年第5期9卷 481-489页

作者： Dandan Liu Xueli Cai Yingying Yang Suying wang Lerong Mei Jing Jing Shan Li Mengxing wang Yun Chen Xia Meng Tiemin Wei yongjun wang Yilong wang Yuesong Pan Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalBeijingChina Department of Clinical Epidemiology and Clinical Trial Capital Medical UniversityBeijingPeople's Republic of China Department of Neurology The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishuiZhejiangChina Lishui Clinical Research Center for Neurological Diseases The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishuiZhejiangChina Cerebrovascular Research Lab The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishuiZhejiangChina Department of Cardiology The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishuiChina Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease BeijingChina

Background Given that associations of Life’s Essential 8(LE8)and cerebral small vessel disease(CSVD)or its imaging markers were unclear,we examined relationship between *** The cross-sectional study included community residents from the PolyvasculaR Evaluation for Cognitive Impairment and vaScular Events *** calculated the total LE8 score,medical LE8 score and behavioural score,and categorised them into low(10)was allocated one *** on modified total CSVD score(0–6 points),WMH or CMB was modified to three grades,and BG-EPVS(N>20)was allocated one *** Among 3061 participants in this study,1424(46.5%)were *** LE8 score was associated with lower total CSVD score(moderate vs low:cOR 0.78,95%CI 0.63 to 0.96;high vs low:cOR 0.44,95%CI 0.33 to 0.59),and the medical score was inversely related to the total CSVD ***,the medical score was inversely related to odds of WMH(p<0.05),modified WMH(p<0.05),lacunes(p<0.05)or BG-EPVS(p<0.05),and the behavioural score were inversely related to the odds of lacunes and *** Higher LE8 score which indicates better cardiovascular status was associated with lower burden of CSVD and its MRI *** studies are needed to examine the causality.

关键词： cerebral behaviour Essential