检索结果-南通市图书馆

Analysis of vibration response characteristics of subway station and superstructure with hard combination

在线全文

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2025年第1期24卷 271-281页

作者： jia Jinglong Xu Weiping Liu Xu Wei yong Key Laboratory of Transportation Tunnel Engineering Ministry of EducationSchool of Civil EngineeringSouthwest Jiaotong UniversityChengdu 610031China State Key Laboratory of Intelligent Geotechnics and Tunnelling Chengdu 610031China China Railway Eryuan Chongqing Survey and Design Institute Co.Ltd. Chongqing 400023China

The vibration response and noise caused by subway trains can affect the safety and comfort of *** study the dynamic response characteristics of subway stations and superstructures under train loads with a hard combination,a numerical model is developed in this *** indoor model test verified the accuracy of the numerical *** influence laws of different hard combinations,train operating speeds and modes were studied and evaluated *** results show that the frequency corresponding to the peak vibration acceleration level of each floor of the superstructure property is concentrated at 10–20 *** vibration response decreases in the high-frequency parts and increases in the lowfrequency parts with increasing distance from the ***,the factors,such as train operating speed,operating mode,and hard combination type,will affect the vibration of the *** vibration response under the reversible operation of the train is greater than that of the unidirectional *** operating speed of the train is proportional to its vibration *** vibration amplification area appears between the middle and the top of the superstructure at a higher train *** vibration acceleration level will exceed the limit value of relevant regulations,and vibration-damping measures are *** the scope of application,this study provides some suggestions for constructing subway stations and superstructures.

关键词： subway station superstructure vibration response hard combination

Upcycling of polyphenylene oxide into 2,6-dimethyl aniline via depolymerization and amination over a Pt/CeO_(2) catalyst

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第2期68卷 520-525页

作者： Shengchao jia Wenke Zhao Xiaohui Liu yong Guo Yanqin Wang State Key Laboratory of Green Chemical Engineering and Industrial Catalysis Research Institute of Industrial CatalysisSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China Shanghai Key Laboratory of Functional Materials Chemistry School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China

Upcycling of plastic waste into N-containing compound is a novel and attractive strategy for its disposal and will opens up a promising direction for the production of value-added ***,an efficient strategy for the depolymerization-amination of polyphenylene oxide(PPO)into 2,6-dimethyl aniline is developed over a simple Pt/CeO_(2) *** C–O linkages of PPO can be selectively broken,producing 2,6-dimethyl phenol and then hydrogenated and aminated to 2,6-dimethyl cyclohexylamine over the Pt/CeO_(2) ***,2,6-dimethyl aniline was produced with high selectivity through the dehydrogenation of 2,6-dimethyl cyclohexylamine in the same *** can be used as the hydrogen-acceptor in the dehydrogenation step and enhance the selectivity of target *** N-containing compound,2,6-dimethyl aniline,is obtained and separated after HCl ***,the Pt/CeO_(2) catalyst exhibit remarkable stability and can sustainably catalyze the synthesis of 2,6-dimethyl aniline in several cycles.

关键词： PPO depolymerization-amination 2,6-dimethyl aniline Pt/CeO_(2)

Viscosity and structure relationship with equimolar substitution of CaO with MgO in the CaO–MgO–Al_(2)O_(3)–SiO_(2)slag melts

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 70-79页

作者： yong Hou Shuo Zhang Jie Dang jia Guo Hanghang Zhou Xuewei Lü College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Chongqing Key Laboratory of Vanadium-Titanium Metallurgy and New Materials Chongqing UniversityChongqing 400044China

Currently,the Al_(2)O_(3)content in the high-alumina slag systems within blast furnaces is generally limited to 16wt%–18.5wt%,making it challenging to overcome this *** most studies that concentrated on managing the MgO/Al_(2)O_(3)ratio or basicity,this paper explored the effect of equimolar substitution of MgO for CaO on the viscosity and structure of a high-alumina CaO-MgO-Al_(2)O_(3)-SiO_(2)slag system,providing theoretical guidance and data to facilitate the application of high-alumina *** results revealed that the viscosity first decreased and then increased with higher MgO substitution,reaching a minimum at 15mol%MgO *** transform infrared spectroscopy(FTIR)results found that the depths of the troughs representing[SiO_(4)]tetrahedra,[AlO_(4)]tetrahedra,and Si-O-Al bending became progressively deeper with increased MgO *** of the Raman spectra showed that the average number of bridging oxygens per Si atom and the X_(Q^(3))/X_(Q^(2))(X_(Q^(i))is the molar fraction of Q^(i) unit,and i is the number of bridging oxygens in a[SiO_(4)]tetrahedral unit)ratio increased from 2.30 and 1.02 to 2.52 and 2.14,respectively,indicating a progressive polymerization of the silicate structure.X-ray photoelectron spectroscopy(XPS)results highlighted that non-bridging oxygen content decreased from 77.97mol% to 63.41mol% with increasing MgO concentration,whereas bridging oxygen and free oxygen contents *** analysis demonstrated a gradual increase in the polymerization degree of the tetrahedral structure with the increase in MgO ***,bond strength is another important factor affecting the slag *** occurrence of a viscosity minimum can be attributed to the complex evolution of bond strengths of non-bridging oxygens generated during depolymerization of the[SiO_(4)]and[AlO_(4)]tetrahedral structures by CaO and MgO.

关键词： aluminosilicate viscosity structure spectroscopy

Structural designs and mechanism insights into electrocatalytic oxidation of 5-hydroxymethylfurfural

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 792-814页

作者： Jing Lei Huijie Zhang jian Yang jia Ran Jiqiang Ning Haiyan Wang yong Hu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials Department of ChemistryZhejiang Normal UniversityJinhua 321004ZhejiangChina Jinhua Advanced Research Institute Jinhua 321019ZhejiangChina Department of Optical Science and Engineering Fudan UniversityShanghai 200438China College of Chemistry and Materials Engineering Zhejiang A&F UniversityHangzhou 311300ZhejiangChina

Biomass conversion offers an efficient approach to alleviate the energy and environmental *** oxidation of 5-hydroxymethylfurfural(HMF)has attracted tremendous attention in the latest few years for the mild synthesis conditions and high conversion efficiency to obtain 2,5-furan dicarboxylic acid(FDCA),but there still remain problems such as limited yield,short cycle life,and ambiguous reaction *** many reviews highlighting a variety of electrocatalysts for electrochemical oxidation of HMF,a detailed discussion of the structural modulation of catalyst and the underlying catalytic mechanism is still *** herein provide a comprehensive summary of the recent development of electrochemical oxidation of HMF to FDCA,particularly focusing on the mechanism studies as well as the advanced strategies developed to regulate the structure and optimize the performance of the electrocatalysts,including heterointerface construction,defect engineering,single-atom engineering,and in situ *** characterization techniques and theoretical calculation methods for mechanism and active site studies are elaborated,and challenges and future directions of electrochemical oxidation of HMF are also *** review will provide guidance for designing advanced catalysts and deepening the understanding of the reaction mechanism beneath electrochemical oxidation of HMF to FDCA.

关键词： Electrochemical oxidation of 5- hydroxymethylfurfural 2,5-Furan dicarboxylic acid Structural design Mechanism Electrocatalysts

Individualized leukemia cell-population profiles in common B-cell acute lymphoblastic leukemia patients

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2013年第4期32卷 213-223页

作者： jian-Hua Yu Jing-Tao Dong yong-qian jia Neng-Gang jiang Ting-Ting Zeng Hong Xu Xian-Ming Mo Wen-Tong Meng Department of Laboratory Medicine Laboratory of Stem Cell Biology State Key Laboratory of Biotherapy West China Hospital Sichuan University

Immunophenotype is critical for diagnosing common B-cell acute lymphoblastic leukemia (common ALL) and detecting minimal residual disease. We developed a protocol to explore the immunophenotypic profiles of common ALL based on the expression levels of the antigens associated with B lymphoid development, including IL-7Rα (CD127), cytoplasmic CD79a (cCD79a), CD19, VpreB (CD179a), and sIgM, which are successive and essential for progression of B cells along their developmental pathway. Analysis of the immunophenotypes of 48 common ALL cases showed that the immunophenotypic patterns were highly heterogeneous, with the leukemic cell population differing from case to case. Through the comprehensive analysis of immunophenotypic patterns, the profiles of patient-specific composite leukemia cell populations could provide detailed information helpful for the diagnosis, therapeutic monitoring, and individualized therapies for common ALL.

关键词： Common B-cell acute lymphoblastic leukemia, immunophenotype, diagnosis, heterogeneity, flow cytometry

Molecular Mechanism Behind the Capture of Fluorinated Gases by Metal–Organic Frameworks

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第5期17卷 407-462页

作者： qian Wang yong Hu Yifan Gu College of Environmental Science and Engineering State Key Laboratory of Pollution Control and Resource ReuseTongji UniversitySiping Rd 1239Shanghai 200092People’s Republic of China Department of Polymeric Materials School of Materials Science and EngineeringTongji UniversityCaoan Road 4800Shanghai 201804People’s Republic of China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092People’s Republic of China Key Laboratory of Cities’Mitigation and Adaptation to Climate Change China Meteorological Administration(CMA)Tongji UniversityShanghai 200092People’s Republic of China

Fluorinated gases(F-gases)play a vital role in the chemical industry and in the fields of air conditioning,refrigeration,health care,and organic ***,the direct emission of waste gases containing F-gases into the atmosphere contributes to greenhouse effects and generates toxic *** porous materials for the energy-efficient capture,separation,and recovery of F-gases is highly ***,as a highly designable porous adsorbents,metal–organic frameworks(MOFs)exhibit excellent selective sorption performance toward F-gases,especially for the recognition and separation of different F-gases with highly similar properties,showing their great potential in F-gases control and *** this review,we discuss the capture and separation of F-gases and their azeotropic,near-azeotropic,and isomeric mixtures in various application scenarios by MOFs,specifically classify and analyze molecular interaction between F-gases and MOFs,and interpret the mechanisms underlying their high performance regarding both adsorption capacity and selectivity,providing a repertoire for future materials *** faced in the transformation research roadmap of MOFs adsorbent separation technologies toward F-gases are also discussed,and areas for future research endeavors are highlighted.

关键词： Fluorinated gas Metal–organic framework Adsorption Separation Molecular interaction

Bufalin Suppresses Esophageal Squamous Cell Carcinoma Progression through Protein Arginine Methyltransferase-6/AKT/Mammalian Target of Rapamycin Pathway Inhibition

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Traditional Chinese Medicine 2025年第01期 148-156页

作者： Yao-Ke jia qian-qian Ju Hui Shi Xin-Xin Si Department of Clinical Medicine Nanjing Medical University Department of Clinical Medicine Medical College of Nantong University Department of Thoracic Surgery School of Medicine Shanghai Chest Hospital Shanghai Jiao Tong University Department of Medical Biology School of Pharmacy Jiangsu Ocean University

Objective: Esophageal squamous cell carcinoma(ESCC), a commonly encountered malignant tumor in the gastrointestinal tract, poses a significant health burden. Bufalin, a pharmacologically active molecule, has been shown to exhibit antitumor activity against various types of cancers. This study investigates the molecular mechanism underpinning the effects of bufalin on ESCCs. Materials and Methods: The impact of bufalin on the proliferation and migration of ESCC cells was evaluated through the utilization of the Cell Counting Kit-8(CCK-8), scratch assay, and transwell assay. In addition, ribonucleic acid(RNA) sequencing was performed to identify genes that were abnormally expressed in response to bufalin treatment. Western blotting was utilized to ascertain the expression levels of protein arginine methyltransferase-6(PRMT6), phosphorylated AKT(p-AKT), and phosphorylated mammalian target of rapamycin(p-m TOR). Cell transfection was then performed to observe the rescue effect of PRMT6 on bufalin. Results: Bufalin displayed a significant time-dependent inhibition of the proliferation, migration, and invasion of ECA109 cells. An RNA sequencing(RNA-seq) analysis revealed that PRMT6 expression was downregulated in the cells treated with bufalin. PRMT6 promoted the proliferation, migration, and invasive potential of ECA109 cells. The overexpression of PRMT6 boosted p-AKT and p-m TOR levels in ECA109 cells and reversed bufalin inhibition. Conclusions: These findings indicate that bufalin exerts its inhibitory effects on ESCCs through the PRMT6/AKT/m TOR signaling pathway. These findings lay the groundwork for bufalin as a promising therapeutic candidate for the treatment of ESCC.

关键词：

Potential preservative mechanisms of cardiac rehabilitation pathways on endothelial function in coronary heart disease

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2025年第1期68卷 158-175页

作者： Wen-Tao Sun jian-yong Du jia Wang Yi-Long Wang Er-Dan Dong Research Center for Cardiopulmonary Rehabilitation University of Health and Rehabilitation Sciences Qingdao Hospital(Qingdao Municipal Hospital)Schoolof Health and Life SciencesUniversityof Health and Rehabilitation SciencesQingdao 266071China Department of Cardiology and Instituteof Vascular Medicine Peking University Third HospitalTheInstituteofCardiovascular SciencesPeking UniversityState Key Laboratoryof Vascular Homeostasisand RemodelingPeking UniversityBeijing 100191China

Cardiac rehabilitation,a comprehensive exercise-based lifestyle and medical management,is effective in decreasing morbidity and improving life quality in patients with coronary heart *** function,an irreplaceable indicator in coronary heart disease progression,is measured by various methods in traditional cardiac rehabilitation pathways,including medicinal treatment,aerobic training,and smoking ***,studies on the effect of some emerging cardiac rehabilitation programs on endothelial function are *** article briefly reviewed the endothelium-beneficial effects of different cardiac rehabilitation pathways,including exercise training,lifestyle modification and psychological intervention in patients with coronary heart disease,and related experimental models,and summarized both uncovered and potential cellular and molecular mechanisms of the beneficial roles of various cardiac rehabilitation pathways on endothelial *** exercise training and some lifestyle interventions,the enhanced bioavailability of nitric oxide,increased circulating endothelial progenitor cells(EPCs),and decreased oxidative stress are major contributors to preventing endothelial dysfunction in coronary heart ***,the preservation of endothelial-dependent hyperpolarizing factors and inflammatory suppression play *** the one hand,to develop more endothelium-protective rehabilitation methods in coronary heart disease,adequately designed and sized randomized multicenter clinical trials should be advanced using standardized cardiac rehabilitation programs and existing assessment *** the other hand,additional studies using suitable experimental models are warranted to elucidate the relationship between some new interventions and endothelial protection in both macro-and microvasculature.

关键词： cardiac rehabilitation coronary heart disease endothelial function

Assessment of future cotton production in the Tarim River Basin under climate model projections and water management

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2025年

作者： Shengru Yue Lunche Wang qian Cao jia Sun School of Geography and Information Engineering， China University of Geosciences College of Hydraulic and Architectural Engineering， Tarim University

Climate change is significantly impacting cotton production in the Tarim River Basin. The study investigated the climate change characteristics from 2021 to 2100 using climate change datasets simulated per the Coupled Model Inter-comparison Project phase six (CMIP6) climatic patterns under the Shared Socioeconomic Pathways SSP2-4.5 and SSP5-8.5. The DSSAT-CROPGRO-Cotton model， along with stepwise multiple regression analyses， was used to simulate changes in the potential yield of seed cotton due to climate change. The results show that while future temperatures in the Tarim River Basin will rise significantly， changes in precipitation and radiation during the cotton-growing season are minimal. Seed cotton yields are more sensitive to low temperatures than to precipitation and radiation. The potential yield of seed cotton under the SSP2-4.5 scenario would increase by 14.8%， 23.7%， 29.0%， and 29.4% in the 2030S， 2050S， 2070S， and 2090S， respectively. In contrast， under the SSP5-8.5 scenario， the potential yield of seed cotton would see increases of 17.5%， 27.1%， 30.1%， and 22.6% respectively. Except for the 2090s under the SSP5-8.5 scenario， future seed cotton production can withstand a 10% to 20% deficit in irrigation. These findings will help develop climate change adaptation strategies for cotton cultivation.

关键词：