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A new strategy for managing presacral venous hemorrhage：bipolar coagulation hemostasis

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Chinese Medical Journal 2010年第23期123卷 3486-3488页

作者： LI Yu-yan CHEN yong XU hui-cheng WANG Dan LIANG Zhi-qing Department of Obstetrics and Gynecology Southwest HospitalThird Military Medical University Chongqing 400038 China

Massive presacral venous hemorrhage is dangerous and difficult to manage. Traditional methods for controlling this condition include packing with laparotomy pads, the use of sterile thumbtacks,1 ligation of the internal iliac vessel,2 and selective arterial embolization.3 These methods are generally ineffective. Recently, several other methods for controlling presacral bleeding have been reported, such as occlusion of the wound with rectus muscle fragment welding,4 oppression with sterile normal saline bags,5 balloon tamponade,6 and the use of endoscopic staples.7 However, these measures fail to arrest the bleeding in some patients, resulting in massive hemorrhage and even death.

关键词： presacral venous plexus massive hemorrhage bipolar coagulation hemostasis

Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future

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Neural Regeneration Research 2025年第4期20卷 946-959页

作者： Zhiyuan Yin Jiahui Kang Xuan cheng hui Gao Shujia Huo Haiwei Xu Key Lab of Visual Damage and Regeneration&Restoration of Chongqing Southwest Eye HospitalSouthwest HospitalThird Military Medical University(Army Medical University)ChongqingChina

Müller glia,as prominent glial cells within the retina,plays a significant role in maintaining retinal homeostasis in both healthy and diseased *** lower vertebrates like zebrafish,these cells assume responsibility for spontaneous retinal regeneration,wherein endogenous Müller glia undergo proliferation,transform into Müller glia-derived progenitor cells,and subsequently regenerate the entire retina with restored ***,Müller glia in the mouse and human retina exhibit limited neural reprogramming.Müller glia reprogramming is thus a promising strategy for treating neurodegenerative ocular disorders.Müller glia reprogramming in mice has been accomplished with remarkable success,through various *** in molecular,genetic,epigenetic,morphological,and physiological evaluations have made it easier to document and investigate the Müller glia programming process in ***,there remain issues that hinder improving reprogramming efficiency and ***,understanding the reprogramming mechanism is crucial toward exploring factors that will improve Müller glia reprogramming efficiency,and for developing novel Müller glia reprogramming *** review describes recent progress in relatively successful Müller glia reprogramming *** also provides a basis for developing new Müller glia reprogramming strategies in mice,including epigenetic remodeling,metabolic modulation,immune regulation,chemical small-molecules regulation,extracellular matrix remodeling,and cell-cell fusion,to achieve Müller glia reprogramming in mice.

关键词： cell fusion chemical small-molecules epigenetic extracellular matrix immune metabolic mice Müller glia neurodegenerative diseases reprogramming retina regeneration

Ideal Bi‑Based Hybrid Anode Material for Ultrafast Charging of Sodium‑Ion Batteries at Extremely Low Temperatures

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Nano-Micro Letters 2025年第3期17卷 152-167页

作者： Jie Bai Jian hui Jia Yu Wang Chun cheng Yang Qing Jiang Key Laboratory of Automobile Materials(Jilin University) Ministry of EducationSchool of Materials Science and EngineeringJilin UniversityChangchun 130022People’s Republic of China

Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at−20°C or ***,the key capability of ultrafast charging at ultralow temperature for SIBs is rarely ***,a hybrid of Bi nanoparticles embedded in carbon nanorods is demonstrated as an ideal material to address this issue,which is synthesized via a high temperature shock *** a hybrid shows an unprecedented rate performance(237.9 mAh g^(−1)at 2 A g^(−1))at−60℃,outperforming all reported SIB anode *** with a Na_(3)V_(2)(PO_(4))_(3)cathode,the energy density of the full cell can reach to 181.9 Wh kg^(−1)at−40°*** on this work,a novel strategy of high-rate activation is proposed to enhance performances of Bi-based materials in cryogenic conditions by creating new active sites for interfacial reaction under large current.

关键词： Bi nanoparticles High temperature shock High-rate activation Ultrafast charging Low-temperature sodium-ion batteries

Preparation and preclinical studies of a hepatic receptor imaging agent

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Nuclear Science and Techniques 1998年第3期 61-64页

作者： Zhang Rong Jun, Jin Jian, Liang Gao Lin, Wan Wei Xing, Tao yong hui and Wang Bo cheng ( State Key Laboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063)

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１ＩｎｔｒｏｄｕｃｔｉｏｎＨｅｐａｔｉｃｂｉｎｄｉｎｇｐｒｏｔｅｉｎ（ＨＢＰ）ｉｓａｎａｓｉａｌｏｇｌｙｃｏｐｒｏｔｅｉｎｒｅｃｅｐｔｏｒ，ｗｈｉｃｈｒｅｓｉｄｅｓｏｎｌｙａｔｔｈｅｃｅｌｓｕｒｆａｃｅｏｆｍａｍｍａｌｉａｎｈｅｐａｔｏｃｙｔｅｓ，...

关键词： m Tc NGA Hepatic receptor imaging agent Bifunctional reagent Glycoprotein

Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

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Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang Wen-Wei Wang Jing-Shui Zhen Bo-cheng Li De-cheng Cai Yang-Yang Du hui Huang Offshore Oil Engineering Co.Ltd. Tianjin300461China Department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model

Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

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Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen Chen Xiaolin Zeng Le Wang Wenwu Zhang Gang Li Xing cheng Peiqiang Su yong Wan Xiang Li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury

Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang Chung Hsien Wu Jiwen Jiang Fei Long Liyuan Han Qifeng Han Yi‑Bing cheng yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

2013-2015年新疆地区职业暴露高危人群布鲁氏菌病血清学检测结果分析

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中国病原生物学杂志 2017年第5期12卷 444-446页

作者：廖新华苟永慧程江石河子大学医学院第一附属医院检验科新疆石河子832008

目的探讨2013-2015年新疆地区职业暴露高危人群布鲁氏菌病的流行特征。方法采用琥红平板凝集试验(RB-PT)及试管凝集试验(SAT)对新疆地区从事养殖、屠宰、挤奶、贩卖、畜牧等职业暴露高危人群进行布鲁氏菌病血清学检测。结果 5 608名职... 详细信息

目的探讨2013-2015年新疆地区职业暴露高危人群布鲁氏菌病的流行特征。方法采用琥红平板凝集试验(RB-PT)及试管凝集试验(SAT)对新疆地区从事养殖、屠宰、挤奶、贩卖、畜牧等职业暴露高危人群进行布鲁氏菌病血清学检测。结果 5 608名职业暴露高危人群血清学检测RB-PT阳性率为1.52%;确诊布鲁氏菌病新发病例55例,感染者12例,平均发病率为0.98%。不同年份新疆地区职业暴露高危人群布鲁氏菌病血清学RB-PT阳性率及布鲁氏菌病发病率差异均具有统计学意义(χ2值分别为8.705和9.512,P均0.05)。布鲁氏菌病主要发生在每年的1-4月份,新发病例主要分布在牛羊养殖、屠宰、挤奶集中的街道,从事牛羊养殖、屠宰、挤奶者占总病例数的89.09%,发热、乏力、多汗、肌肉关节疼痛是该病常见临床表现。结论新疆地区职业暴露高危人群存在布鲁氏菌病感染,因此应加强对当地职业暴露高危人群的布鲁氏菌病健康教育,提高防护意识,做好畜类的检验检疫工作,从而控制布鲁氏菌病疫情。

关键词：布鲁氏菌病职业暴露高危人群血清学检测

Control of Corner Separation for a Linear Compressor Cascade via Bionic Slanting Riblets at the Endwall

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Journal of Thermal Science 2025年第1期34卷 129-144页

作者： ZHANG Peng LI yonghong cheng Rixin Key Laboratory of Civil Aircraft Airworthiness Technology Civil Aviation University of China College of Aeronautical Engineering Civil Aviation University of China

A new passive control approach,utilizing bionic slanting riblets,is employed to mitigate the flow close to the blade endwall in a linear cascade,and its effectiveness and mechanism in controlling corner separation are investigated through numerical *** slanting riblets are positioned at the endwall upstream of the cascade channel,and the influence of riblet height,yaw angle and relative position on the control of corner separation is *** findings indicate that the application of slanting riblets can efficiently counteract corner separation across the stable operational ***,the introduction of riblets with a height of merely 0.1 times the boundary layer thickness results in a significant reduction in total pressure loss by up to 14.53%,while simultaneously enhancing the static pressure coefficient by 21.74%.Flow analysis reveals that minute vortices produced within the riblet channels tend to coalesce,forming a potent large-scale vortex near the boundary layer's base *** phenomenon results in reduced additional losses compared to conventional vortex ***,the induced vortex promotes enhanced mixing between the mainstream flow and boundary layer,inhibiting the lateral displacement of low-energy fluids within the endwall boundary ***,this delays the onset of separation vortex formation and eliminates vortex rings in the corner region,ultimately enhancing the aerodynamic efficiency of the cascade.

关键词： additional losses compressor cascade corner separation slanting riblets vortex generator