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Chinese Chemical Letters 2024年第9期35卷 179-182页

作者： Lei Zhou Youjun Zhou Lizhen Fang Yiqiao Bai Yujia Meng Liang Li Jie Yang yong yao School of Chemical and Environmental Engineering Shanghai Institute of TechnologyShanghai 201418China School of Chemistry and Chemical Engineering Nantong City Key Laboratory of Life-Organic ChemistryNantong UniversityNantong 226019China College of Science Nanjing Forestry UniversityNanjing 210037China

Photosynthesis is the process through which living plants utilize photosynthetic pigments,such as chlorophyll,to convert CO_(2)and water into organic compounds and release O_(2)under visible *** this study,we have successfully constructed a fluorescent supramolecular polymer(P5Py_(2)/Zn/Gen)n by employing orthogonal pillar[5]arene-based molecular recognition and metal ion *** the supramolecular polymer,the guest molecule Gen unit acts as a light-harvesting moiety,as the ACQ effect is inhibited by host-guest interactions,while the(Py)_(2)/Zn center serves as a catalytic *** employing this orthogonal self-assembly strategy,we have enhanced the stability of both the donor and acceptor in catalyzing the reduction of p-nitrophenol to ***,this photocatalyst can be reused at least 5 times without significant conversion *** findings provide a pathway for constructing a recyclable artificial LHS that mimics the entire photosynthesis process.

关键词： Pillararenes Light-harvest Supramolecular polymer Photosynthesis Orthogonal self-assembly

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Recent advances in the magnetic reconnection, dipolarization, and auroral processes at giant planets from the perspective of comparative planetology

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Earth and Planetary Physics 2024年第5期8卷 659-672页

作者： ZhongHua yao RuiLong Guo yong Wei Bertrand Bonfond Denis Grodent BinZheng Zhang William R.Dunn ZuYin Pu Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of Sciences College of Earth and Planetary Sciences University of Chinese Academy of Sciences Laboratoire de Physique Atmosphérique et Planétaire STAR InstituteUniversitéde Liège Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment Institute of Space SciencesShandong University Department of Earth Sciences the University of Hong Kong Department of Physics and Astronomy University College London School of Earth and Space Sciences Peking University

Magnetic reconnection and dipolarization are crucial processes driving magnetospheric dynamics, including particle energization, mass circulation, and auroral processes, among others. Recent studies have revealed that these processes at Saturn and Jupiter are fundamentally different from the ones at Earth. The reconnection and dipolarization processes are far more important than previously expected in the dayside magnetodisc of Saturn and potentially Jupiter. Dayside magnetodisc reconnection was directly identified by using Cassini measurements(Guo RL et al., 2018b) and was found to be drizzle-like and rotating in the magnetosphere of Saturn(Delamere et al., 2015b; yao ZH et al., 2017a; Guo RL et al., 2019). Moreover, magnetic dipolarization could also exist at Saturn's dayside(yao ZH et al., 2018), which is fundamentally different from the terrestrial situation. These new results significantly improve our understanding of giant planetary magnetospheric dynamics and provide key insights revealing the physics of planetary aurorae. Here, we briefly review these recent advances and their potential implications for future investigations.

关键词： magnetosphere magnetic reconnection magnetic depolarization

Association between Serum Ferritin Levels and Metabolic-associated Fatty Liver Disease in Adults:a Cross-sectional Study Based on the NHANES

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Current Medical Science 2024年第3期44卷 494-502页

作者： Jiang-hui LI Xue-yao MA Yun YI Lu-rao LI Zhi-yong XU Ying CHANG Department of Gastroenterology Zhongnan Hospital of Wuhan UniversityWuhan430071China Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Diseases Wuhan430071China Endoscopy Center The People’s Hospital of YingshanHuanggang438799China

Objective Ferritin,initially acting as an iron-storage protein,was found to be associated with metabolic *** study was designed to investigate the association between serum ferritin and metabolic-associated fatty liver disease(MAFLD)using data from the National Health and Nutrition Examination Survey(NHANES)of the United State of *** A cross-sectional study was conducted,enrolling a total of 2145 participants from the NHANES in the 2017–2018 *** steatosis and liver fibrosis were assessed by ultrasound images and several non-invasive *** regression analysis was conducted to determine the associations between serum ferritin concentration and MAFLD and liver *** The analysis revealed that participants with higher serum ferritin levels(Q3 and Q4 groups)had a higher prevalence of MAFLD than those with the lowest serum ferritin levels[Q3 vs.Q1:OR=2.17(1.33,3.53),P<0.05 in fatty liver index(FLI);Q4 vs.Q1:OR=3.13(1.91,5.13),P<0.05 in FLI].Additionally,participants with the highest serum ferritin levels(Q4 group)displayed a higher prevalence of liver fibrosis[Q4 vs.Q1:OR=2.59(1.19,5.62),P<0.05 in liver stiffness measurement;OR=5.06(1.12,22.94),P<0.05 in fibrosis-4 index],with significantly increased risk observed in participants with concomitant diabetes[OR=7.45(1.55,35.72),P=0.012].Conclusion Our study revealed that elevated serum ferritin levels are associated with a higher prevalence of MAFLD and advanced liver fibrosis in *** serum ferritin levels combined with diabetes are important risk factors for liver fibrosis.

关键词： serum ferritin liver fibrosis metabolic-associated fatty liver disease National Health and Nutrition Examination Survey

Broadband high-efficiency plasmonic metalens with negative dispersion characteristic

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Photonics Research 2024年第4期12卷 813-820页

作者： yong-qiang LIU yong ZHU HONGCHENG YIN JINHAI SUN YAN WANG yongXING CHE National Key Laboratory of Scattering and Radiation Beijing 100854China

Controlling the dispersion characteristic of metasurfaces(or metalenses) along a broad bandwidth is of great importance to develop high-performance broadband metadevices. Different from traditional lenses that rely on the material refractive index along the light trajectory, metasurfaces or metalenses provide a new regime of dispersion control via a sub-wavelength metastructure, which is known as negative chromatic ***, broadband metalenses design with high-performance focusing especially with a reduced device dimension is a significant challenge in society. Here, we design, fabricate, and demonstrate a broadband highperformance diffractive-type plasmonic metalens based on a circular split-ring resonator metasurface with a relative working bandwidth of 28.6%. The metalens thickness is only 0.09λ0(λ0is at the central wavelength),which is much thinner than previous broadband all-dielectric metalenses. The full-wave simulation results show that both high transmissive efficiency above 80%(the maximum is even above 90%) and high average focusing efficiency above 45%(the maximum is 56%) are achieved within the entire working bandwidth of 9–12 ***, an average high numerical aperture of 0.7(NA = 0.7) of high-efficiency microwave metalens is obtained in the simulations. The broadband high-performance metalens is also fabricated and experimental measurements verify its much higher average focusing efficiency of 55%(the maximum is above 65% within the broad bandwidth) and a moderate high NA of 0.6. The proposed plasmonic metalens can facilitate the development of wavelength-dependent broadband diffractive devices and is also meaningful to further studies on arbitrary dispersion control in diffractive optics based on plasmonic metasurfaces.

关键词： resonator dispersion high

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Searches for multi-Z boson productions and anomalous gauge boson couplings at a muon collider

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Chinese Physics C 2024年第10期48卷 31-39页

作者： Ruobing Jiang Chuqiao Jiang Alim Ruzi Tianyi Yang yong Ban qiang Li School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China

Multi-boson productions can be exploited as novel probes either for standard model precision tests or new physics searches,and have become a popular research topic in ongoing LHC experiments and future collider studies,including those for electron–positron and muon–muon *** this study,we focus on two examples,i.e.,ZZZ direct productions through μ^(+)μ^(-) annihilation at a 1TeV muon collider,and ZZ productions through vector boson scattering(VBS)at a 10TeV muon collider,with an integrated luminosity of 10 ab^(-1).Various channels are considered,including ZZZ→4l2v and ZZZ→4l+*** expected significance on these multi-Z boson production processes is reported based on a detailed Monte Carlo study and signal background *** on anomalous gauge boson couplings are also presented.

关键词： TeV physics muon collider multi-Z boson anomalous quartic gauge boson interactions

Clinical review and literature analysis of hepatic epithelioid angiomyolipoma in alcoholic cirrhosis: A case report

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World Journal of Clinical Cases 2024年第14期12卷 2382-2388页

作者： Jing-qiang Guo Jia-Hui Zhou Kun Zhang Xin-Liang Lv Chao-yong Tu Department of Hepatobiliary and Pancreatic Surgery Lishui Municipal Central HospitalLishui 323000Zhejiang ProvinceChina Department of Pathology Lishui Municipal Central HospitalLishui 323000Zhejiang ProvinceChina Department of General Surgery The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND Hepatic epithelioid angiomyolipoma(HEA)has a low incidence and both clinical manifestations and imaging lack ***,it is easy to misdiagnose HEA as other tumors of the liver,especially in the presence of liver diseases such as hepatitis *** article reviewed the diagnosis and treatment of a patient with HEA and alcoholic cirrhosis,and analyzed the literature,in order to improve the understanding of this *** SUMMARY A 67-year-old male patient with a history of alcoholic cirrhosis was admitted due to the discovery of a space-occupying lesion in the *** on the patient’s history,laboratory examinations,and imaging examinations,a malignant liver tumor was considered and laparoscopic partial hepatectomy was *** pathology showed *** outpatient follow-up,the patient showed no sign of *** HEA is difficult to make a definite diagnosis before *** has the poten-tial for malignant *** conditions permit,surgical treatment is recom-mended.

关键词： Hepatic epithelioid angiomyolipoma Alcoholic cirrhosis Magnetic resonance imaging Computed tomography Immunohistochemistry Misdiagnose analysis Case report

Performance of the walking trail making test in older adults with white matter hyperintensities

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World Journal of Psychiatry 2024年第1期14卷 102-110页

作者： Hong-Yi Zhao Zhi-qiang Zhang yong-Hua Huang Hong Li Fang-Yuan Wei Department of Neurology No.984 Hospital of PLABeijing 100094China Department of Neurology The Seventh Medical Center of PLA General HospitalBeijing 100700China Mental Health Institute of Inner Mongolia Autonomous Region The Third Hospital of Inner Mongolia Autonomous RegionHohhot 010010Inner Mongolia Autonomous RegionChina Department of Neurosurgery No.984 Hospital of PLABeijing 100094China Department of Hand and Foot Surgery Beijing University of Chinese Medicine Third Affiliated HospitalBeijing 100029China Engineering Research Center of Chinese Orthopaedic and Sports Rehabilitation Artificial Intelligent Ministry of EducationBeijing 100029China

BACKGROUND Several studies have reported that the walking trail making test(WTMT)completion time is significantly higher in patients with developmental coordination disorders and mild cognitive *** hypothesized that WTMT performance would be altered in older adults with white matter hyperintensities(WMH).AIM To explore the performance in the WTMT in older people with *** In this single-center,observational study,25 elderly WMH patients admitted to our hospital from June 2019 to June 2020 served as the WMH group and 20 participants matched for age,gender,and educational level who were undergoing physical examination in our hospital during the same period served as the control *** participants completed the WTMT-A and WTMT-B to obtain their gait parameters,including WTMT-A completion time,WTMT-B completion time,speed,step length,cadence,and stance phase *** matter lesions were scored according to the Fazekas *** neuropsychological assessments were carried out to assess cognitive *** relationships between WTMT performance and cognition and motion in elderly patients with WMH were analyzed by partial Pearson correlation *** Patients with WMH performed significantly worse on the choice reaction test(CRT)(0.51±0.09 s vs 0.44±0.06 s,P=0.007),verbal fluency test(VFT,14.2±2.75 vs 16.65±3.54,P=0.012),and digit symbol substitution test(16.00±2.75 vs 18.40±3.27,P=0.010)than participants in the control *** WMH group also required significantly more time to complete the WTMT-A(93.00±10.76 s vs 70.55±11.28 s,P<0.001)and WTMT-B(109.72±12.26 s vs 82.85±7.90 s,P<0.001).WTMT-A completion time was positively correlated with CRT time(r=0.460,P=0.001),while WTMT-B completion time was negatively correlated with VFT(r=-0.391,P=0.008).On the WTMT-A,only speed was found to statistically differ between the WMH and control groups(0.803±0.096 vs 0.975±0.050 m/s,P<0.001),whereas on the WTMT-B,the WMH group exhibited a sign

关键词： White matter hyperintensities Cognitive dysfunction Motor deficits Gait analysis Trail making test Small vessel disease

Efficacy and Safety of Bufei Jiedu Granules in Treating Multidrug-Resistant Pulmonary Tuberculosis:A Multi-center,Double-Blinded and Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第7期30卷 579-587页

作者： ZHANG Shao-yan QIU Lei ZHANG Shun-xian XIAO He-ping CHU Nai-hui ZHANG Xia ZHANG Hui-qiang ZHENG Pei-yong ZHANG Hui-yong LU Zhen-hui Institute of Respiratory Diseases Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai200032China Clinical Research Center Shanghai University of Traditional Chinese MedicineShanghai200032China Department of Tuberculosis Shanghai Pulmonary HospitalTongji UniversityShanghai200433China Department of Tuberculosis Beijing Chest HospitalCapital Medical UniversityBeijing101100China Department of Tuberculosis the Second Hospital of NanjingNanjing210003China Department of Tuberculosis the First Hospital Affiliated to Xinxiang Medical CollegeXinxiangHenan Province453100China

Objective: To assess the efficacy and safety of Bufei Jiedu(BFJD) Granules as adjuvant therapy for patients with multidrug-resistant pulmonary tuberculosis(MDR-PTB). Methods: A large-scale, multi-center, double-blinded, and randomized controlled trial was conducted in 18 sentinel hospitals in China from December 2012 to December 2016. A total of 312 MDR-PTB patients were randomly assigned to BFJD Granules or placebo groups(1:1) using a stratified randomization method, which both received the long-course chemotherapy regimen for 18 months(6 Am-Lfx-P-Z-Pto, 12 Lfx-P-Z-Pto). Meanwhile, patients in both groups also received BFJD Granules or placebo twice a day for a total of 18 months, respectively. The primary outcome was cure rate. The secondary outcomes included time to sputum-culture conversion, changes in lung cavities and quality of life(QoL) of patients. Adverse reactions were monitored during and after the trial. Results: A total of 216 cases completed the trial, 111 in the BFJD Granules group and 105 in the placebo group. BFJD Granules, as adjuvant treatment, increased the cure rate by 13.6% at the end of treatment, compared with the placebo(58.4% vs. 44.8%, P=0.02), and accelerated the median time to sputum-culture conversion(5 months vs. 11 months). The cavity closure rate of the BFJD Granules group(50.6%, 43/85) was higher than that of the placebo group(32.1%, 26/81;P=0.02) in patients who completed the treatment. At the end of the intensive treatment, according to the 36-item Short Form, the BFJD Granules significantly improved physical functioning, general health, and vitality of patients relative to the placebo group(all P<0.01). Overall, the death rates in the two groups were not significantly different;5.1%(8/156) in the BFJD Granules group and 2.6%(4/156) in the placebo group. Conclusions: Supplementing BFJD Granules with the long-course chemotherapy regimen significantly increased the cure rate and cavity closure rate, and rapidly improved QoL of pati

关键词： alternative medicine Chinese herbal formula Bufei Jiedu Granules multidrug-resistant tuberculosis long-course chemotherapy regimen randomized controlled trial

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Transcriptome analysis suggests broad jejunal alterations in Linghu’s obesity-diarrhea syndrome:A pilot study

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World Journal of Gastroenterology 2024年第21期30卷 2777-2792页

作者： Xiao-Tong Niu Xiang-yao Wang Yan Wang Ke Han Nan Ru Jing-Yuan Xiang En-qiang Linghu Medical School of Chinese PLA Chinese PLA General HospitalBeijing 100853China Department of Gastroenterology The First Medical Center of Chinese PLA General HospitalBeijing 100853China School of Medicine Nankai UniversityTianjin 300071China

BACKGROUND Obesity is associated with a significantly increased risk for chronic diarrhea,which has been proposed as Linghu’s obesity-diarrhea syndrome(ODS);however,its molecular mechanisms are largely *** To reveal the transcriptomic changes in the jejunum involved in *** In a cohort of 6 ODS patients(JOD group),6 obese people without diarrhea(JO group),and 6 healthy controls(JC group),high-throughput sequencing and bioinformatics analyses were performed to identify jejunal mucosal mRNA expression alterations and dysfunctional biological *** another cohort of 16 ODS patients(SOD group),16 obese people without diarrhea(SO group),and 16 healthy controls(SC group),serum diamine oxidase(DAO)and D-lactate(DLA)concentrations were detected to assess changes in intestinal barrier *** The gene expression profiles of jejunal mucosa in the JO and JC groups were similar,with only 1 differentially expressed gene(DEG).The gene expression profile of the JOD group was significantly changed,with 411 DEGs compared with the JO group and 211 DEGs compared with the JC group,129 of which *** enrichment analysis of these DEGs showed that the biological processes such as digestion,absorption,and transport of nutrients(especially lipids)tended to be up-regulated in the JOD group,while the biological processes such as rRNA processing,mitochondrial translation,antimicrobial humoral response,DNA replication,and DNA repair tended to be down-regulated in the JOD *** DEGs(CDT1,NHP2,EXOSC5,EPN3,NME1,REG3A,PLA2G2A,and PRSS2)may play a key regulatory role in the pathological process of ODS,and their expression levels were significantly decreased in ODS patients(P<0.001).In the second cohort,compared with healthy controls,the levels of serum intestinal barrier function markers(DAO and D-LA)were significantly increased in all obese individuals(P<0.01),but were higher in the SOD group than in the SO group(P<0.001).CONCLUSION Compared with health

关键词： Obesity Chronic diarrhea Jejunum Transcriptome Intestinal barrier

Percutaneous ultrasound-guided coaxial core needle biopsy for the diagnosis of multiple splenic lesions: A case report

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 616-621页

作者： Sha-Hong Pu Wu-yong-Ga Bao Zhen-Peng Jiang Rui Yang qiang Lu Department of Medical Ultrasound West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND The overlap of imaging manifestations among distinct splenic lesions gives rise to a diagnostic ***,a definitive diagnosis primarily relies on his-tological *** ultrasound(US)-guided coaxial core needle biopsy(CNB)not only procures sufficient tissue to help clarify the diagnosis,but reduces the incidence of puncture-related *** SUMMARY A 41-year-old female,with a history of pulmonary tuberculosis,was admitted to our hospital with multiple indeterminate splenic ***-scale ultrasono-graphy demonstrated splenomegaly with numerous well-defined hypoechoic *** contrast-enhanced computed tomography(CT)showed an en-larged spleen with multiple irregular-shaped,peripherally enhancing,hypodense *** emission CT revealed numerous abnormal hyperglycemia *** imaging findings strongly indicated the possibility of infectious disease as the primary concern,with neoplastic lesions requiring *** obtain the precise pathological diagnosis,the US-guided coaxial CNB of the spleen was ca-rried *** patient did not express any discomfort during the *** Percutaneous US-guided coaxial CNB is an excellent and safe option for obtaining precise splenic tissue samples,as it significantly enhances sample yield for exact pathological analysis with minimum trauma to the spleen parenchyma and sur-rounding tissue.

关键词： Spleen Splenic disease Ultrasound Biopsy Ultrasound-guided coaxial core needle biopsy Case report