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Efficient implementation of a cubic-convolution based image scaling engine

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Journal of Zhejiang University-Science C(Computers and Electronics) 2011年第9期12卷 743-753页

作者： Xiang WANG yong DING ming-yu liu Xiao-lang YAN Institute of VLSI Design Zhejiang University Hangzhou 310027 China

In video applications, real-time image scaling techniques are often required. In this paper, an efficient implementation of a scaling engine based on 4×4 cubic convolution is proposed. The cubic convolution has a better performance than other traditional interpolation kernels and can also be realized on hardware. The engine is designed to perform arbitrary scaling ratios with an image resolution smaller than 2560× 1920 pixels and can scale up or down, in horizontal or vertical direction. It is composed of four fimctional units and five line buffers, which makes it more competitive than conventional architectures. A strict fixed-point strategy is applied to minimize the quantization errors of hardware realization. Experimental results show that the engine provides a better image quality and a comparatively lower hardware cost than reference implementations.

关键词： Cubic-convolution Hardware implementation Interpolation Engine

Interaction between systemic iron parameters and left ventricular structure and function in the preserved ejection fraction population:a two-sample bidirectional Mendelian randomization study

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Journal of Geriatric Cardiology 2024年第1期21卷 64-80页

作者： Xiong-Bin MA yong-ming liu Yan-Lin LV Lin QIAN The First Clinical Medical College of Lanzhou University LanzhouGansuChina Geriatric Cardiovascular Department and Gansu Clinical Research Center for Geriatric Diseases First Hospital of Lanzhou UniversityGansuChina

BACKGROUND Left ventricular(LV)remodeling and diastolic function in people with heart failure(HF)are correlated with iron status;however,the causality is *** Mendelian randomization(MR)study investigated the bidirectional causal relationship between systemic iron parameters and LV structure and function in a preserved ejection fraction *** Transferrin saturation(TSAT),total iron binding capacity(TIBC),and serum iron and ferritin levels were extracted as instrumental variables for iron parameters from meta-analyses of public genome-wide association *** without myocardial infarction history,HF,or LV ejection fraction(LVEF)<50%(n=16,923)in the UK Biobank Cardiovascular Magnetic Resonance Imaging Study constituted the outcome *** dataset included LV end-diastolic volume,LV endsystolic volume,LV mass(LVM),and LVM-to-end-diastolic volume ratio(LVMVR).We used a two-sample bidirectional MR study with inverse variance weighting(IVW)as the primary analysis method and estimation methods using different algorithms to improve the robustness of the *** In the IVW analysis,one standard deviation(SD)increased in TSAT significantly correlated with decreased LVMVR(β=-0.1365;95%confidence interval[CI]:-0.2092 to-0.0638;P=0.0002)after Bonferroni ***,no significant relationships were observed between other iron and LV *** Bonferroni correction,reverse MR analysis showed that one SD increase in LVEF significantly correlated with decreased TSAT(β=-0.0699;95%CI:-0.1087 to-0.0311;P=0.0004).No heterogeneity or pleiotropic effects evidence was observed in the *** We demonstrated a causal relationship between TSAT and LV remodeling and function in a preserved ejection fraction population.

关键词： fraction function parameters

A highly selective solid-contact electrode for Ag^+ based on a monoazathiacrown ether ionophore

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Chinese Chemical Letters 2012年第4期23卷 488-491页

作者： Shun Yang Yu Lan Ju Fu Hai Li yong ming liu Jun Feng Fang Key Laboratory of Coastal Zone Environmental Processes Yantai Institute of Coastal Zone ResearchChinese Academy of SciencesYantai 264003China Zhejiang Textile and Fashion College Ningbo 31521lChina Chemistry and Chemical Engineering College Yantai UniversityYantai 264005China Ningbo Institute of Material Technology&Engineering Chinese Academy of SciencesNingbo 315201China

A new solid-contact Ag~＋-selective electrode was prepared with 9,10,12,13,24,25-hexahydro-5H,15H,23H-dibenzo [b,q][1,7,10,13,19,4,16]-entathiadiazacyclodocosine-6,16（7H,17H）-dione as ionophore,and cc,a-dihexylsexithiophene（DH- 6T） ion-to-electron *** sensor exhibited a working concentration range of 10~8 to 10^（-3） mol/L,with a near-Nernstian slope of 55.1±0.2 mV/dec and detection limit of 1.7×10^（-9） mol/*** fabricated electrodes demonstrated excellent selectivity over the most common monovalent and divalent cations.

关键词： Solid contact Silver Ion-selective electrodes Low detection limit

Effects of nociceptin/orphanin FQ on rats with cathartic colon

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World Journal of Gastroenterology 2007年第1期13卷 141-145页

作者： Hai-Yan Li Xiang Yan Quan-Lai Xue yong-Ning Zhou Yan Gao Rui Wang yong-ming liu Jun-Tao Ran Department of Gastroenterology the Affiliated Hospital of Jinchuan Corporation Company Jinchang 737100 Gansu Province China Department of Geriatrics 1st Affiliated Hospital of LanzhouUnivercity Lanzhou 730000 Gansu Province China Department of Life Science Lanzhou UniversityLanzhou 730000 Gansu Province China

AIM： To demonstrate the change and effect of nodceptin/orphanin FQ in the colon of rats with cathartic colon. METHODS： The cathartic colon model was established by feeding rats rhubarb for 3 mo, the changes of colonic electromyography were investigated by both suspension muscle strips test and serosal recordings of colonic myoelectrical activity. Immunohistochemical staining （S-P methods） and image analysis were used to determine the changes of nociceptin/orphanin FQ in the proximal colon and distal colon of rats with cathartic colon. RESULTS： Suspension muscle strips test in vitro showed OFQ （10^-9-10^-6 mol/L） concentration dependently caused an immediate tonic contraction in the isolated colon. But the increase of tension in cathartic colon was less than control groups （P〈0.01）. Intravenous administration of OFQ （1 μg/kg） caused phasic contractions in the proximal colon, while the amplitude of phasic contractions caused by OFQ in cathartic colon was much lower than that in the control groups （2.58±0.41 vs 4.16 ± 0.53, t = -2.6, P = 0.012）. OFQ was highly expressed in the myenteric plexus of the rat colon but not in the musde cells. The immunoreactivity of OFQ in the proximal colon in cathartic colon rats decreased significantly compared with the control group （P = 0.001）. CONCLUSION： Colonic smooth muscle of cathartic colon showed low sensitivity to the stimulation of OFQ, suggesting that it might be caused by the abnormal distribution of OFQ or the abnormalities of receptors, leading to the disorganization of dynamic and incoordinated contractions.

关键词： Gastroenterology

A ladder conjugated polymer transducer for solid-contact Cu^(2+)-selective electrodes

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Chinese Chemical Letters 2014年第2期25卷 364-366页

作者： Shun-Yang Yu Yan-Cang Li Tao Xiong Qun Yuan yong-ming liu Zhong-Yi Yuan Yi Xiao Key Laboratory of Coastal Environmental Processes and Ecological Remediation Yantai Institute of Coastal Zone Research(YIC)Chinese Academy of Sciences(CAS)Shandong Provincial Key Laboratory of Coastal Environmental ProcessesYICCAS Chemistry and Chemical Engineering College.Yantai University Physical Science and Technical College Dalian University State Key Laboratory of Fine Chemicals Dalian University of Technology

In recent years, there has been a pronounced interest in solid-contact ion-selective electrodes （SC-ISEs）, with emphasis on the use of conducting polymers as ion-to-electron transducer. In this work, a ladder conjugated polymer, thieno[3,2-b]thiophene （LCPT）, was investigated in fabricating Cu2＋-selective electrodes for the first time. The resulting electrodes were characterized by electrochemical impedance spectroscopy （EIS）, chronopotentiometry, and the water layer test. Results proved that the active LCPT facilitates the ion-to-electron transduction, and avoids the detrimental aqueous layer formed at the interface of SC-ISEs.

关键词： Ladder polymer Solid contact Ion-selective electrode Copper

Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats

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Chinese Medical Journal 2006年第10期119卷 814-821页

作者： SUN Shu-zhen WANG Yi LI Qian TIAN yong-jie liu ming-hua YU yong-hui Department of Pediatrics Shandong Provincial Hospital ShandongUniversity Jinan 250021 China

Background Excessive deposition of extraceUular matrix （ECM） in the kidney is the hallmark of diabetic nephropathy. Increased matrix synthesis has been well documented but the effects of diabetes on degradative pathways, particularly in the in vivo setting. The renal protective effect of these pathways on matrix accumulation has not been fully elucidated. The present study was understaken to investigate the activity of matrix metalloproteinase-2 （MMP-2）, the expression of MMP-2 and tissue inhibitor of metalloproteinase-2 （TIMP-2） in kidney tissues of diabetic rats, and to explore the degradative pathway of type Ⅳ collagen （Ⅳ-C） and the renal protective effects of ACE inhibition- benazepril.

关键词： angiotensin converting enzyme inhibitors diabetic nephropathy renal function matrix metalloproteinase-2 tissue inhibitor of metalloproteinase-2

Inhibition of VASP Gene Expression on HUVEC by Antisense Oligonucleotides

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生物医学工程学杂志 2005年第S1期22卷 149-150页

作者： De-Ling ZHANG Jing-Ping Ou YANG yong-ming liu Nian WANG(Department of Pathophysiology,Medical College of Wuhan University,Wuhan 430071,China) Department of Pathophysiology Medical College of Wuhan University Wuhan 430071 China

1 IntroductionVasodilator-stimulated phosphoprotein ( VASP ), a proline-rich founding member of the Ena-VASP proteinfamily, was discovered both as a substrate of cyclic AMPand cyclic GMP-dependent protein kinases and a component of the actin-based cytoskeleton. VASP is associated with focal adhesions, actin filaments, and highly dynamic membrance regions and is a crucial factor in regulating actin remodelling and associated processes such as cellcell adhesion, platelet aggregation and actin-based motility. Phosphorylation may significantly alter the actin binding properties of VASP and phosphorylation of Ser157causes the phosphorylation-induced mobility shift in SDSPAGE from 46 KDa to 50 KDa. Some articles indicate changes of the VASP phosphorylation expression participate in the regulation of actin remodelling in HUVEC under different level of laminar flow[1] . However, a number of seemingly conflicting studies have confused the VASP field, pointing to roles for these proteins in both promotion and inhibition of actin-dependent processes.

关键词： VASP HUVEC

Identification of QTLs for Rice Cold Tolerance at Plumule and 3-Leaf-Seedling Stages by Using QTLNetwork Software

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Rice science 2010年第4期17卷 282-287页

作者： JI Zhi-juan ZENG Yu-xiang ZENG Da-li MA Liang-yong LI Xi-ming liu Bing-xin YANG Chang-deng State Key Laboratory of Rice Biology China National Rice Research Institute Hangzhou 310006 China

A doubled haploid （DH） population consisted of 120 lines, derived from a cross between an indica vadety, TN1, and a japonica variety, Chunjiang 06, was used to identify QTLs controlling rice cold tolerance at the plumule and 3-leaf-seedling stages by using the QTLNetwork software. The percentages of normal plumules after 4~C treatments for 7 d, 9 d, 11 d, and 14 d, as well as the cold stress tolerance index （CSTI） and the withering index （WI） of rice seedling were investigated. A total of five single-effect QTLs, each for percentages of normal plumules after 4℃treatments for 9 d, 11 d and 14 d, and CSTI and WI, respectively were identified. The QTLs for the percentages of normal plumules after low temperature treatments for g d, 11 d and 14 d were on chromosomes 4, 2 and 11, accounting for 14.1%, 17.3% and 21.5% of the phenotypic variation, respectively. QTLs for CSTI and WI were on chromosomes 10 and 1, respectively. Two pairs of epistatic loci were identified, but none of the epistatic loci involved the single-effect QTLs. The RM528-RM340 interval on chromosome 6 interacted with the RM278-RM3919B interval on chromosome 9 for CSTI, and the epistatic interaction accounted for 17.7% of the phenotypic variation. A pair of epistatic loci was identified for WI, the RM246-RM5461 interval on chromosome 1 interacted with the ISA-RM447 interval on chromosome 8, which accounted for 22.6% of the phenotypic variation.

关键词： rice cold tolerance quantitative trait loci plumule QTLNetwork software

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水润滑橡胶轴承支承转子系统动力学特性研究

船舶力学 2017年第5期21卷 584-594页

作者：史永峰李明刘刚何琳西安科技大学理学院力学系西安710054 海军工程大学振动与噪声研究所武汉430033

文章研究了水润滑橡胶轴承的动态特性及其在橡胶轴承支承下转子系统的动力学行为。首先,考虑了动压润滑和橡胶体的弹性变形等因素后,建立了水润滑橡胶轴承的水弹性动力润滑数学模型,根据载荷增量法与差分法,分析了轴承的刚度和阻尼。然... 详细信息

文章研究了水润滑橡胶轴承的动态特性及其在橡胶轴承支承下转子系统的动力学行为。首先,考虑了动压润滑和橡胶体的弹性变形等因素后,建立了水润滑橡胶轴承的水弹性动力润滑数学模型,根据载荷增量法与差分法,分析了轴承的刚度和阻尼。然后,选择集总参数法离散化转子系统,根据分析力学方法推导了水润滑橡胶轴承耦合转子系统的运动微分方程。最后,通过广义逆迭代法,研究了水润滑橡胶轴承支承的转子系统的动力学特性和稳定性,得到了转子-轴承系统的坎贝尔曲线,临界转速与振型以及失稳转速等。结果表明偏心率、间隙比、转速及长径比对轴承的动态特性的影响比较显著;轴承的水弹性润滑特性对系统的临界转速影响较大,橡胶轴承的弹性对系统的稳定性影响次之。

关键词：水润滑橡胶轴承转子系统动态特性临界转速稳定性