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Functional genomics in the rice blast fungus to unravel the fungal pathogenicity

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第10期9卷 747-752页

作者： Junhyun JEON Jaehyuk CHOI Jongsun PARK yong-hwan lee Department of Agricultural Biotechnology Center for Fungal Genetic Resources and Center for Agricultural BiomaterialsSeoul National UniversitySeoul 151-921Korea Department of Agricultural Biotechnology Center for Fungal Genetic Resourcesand Center for Agricultural BiomaterialsSeoul National UniversitySeoul 151-921Korea

A rapidly growing number of successful genome sequencing projects in plant pathogenic fungi greatly increase the demands for tools and methodologies to study fungal pathogenicity at genomic scale. Magnaporthe oryzae is an economically important plant pathogenic fungus whose genome is fully sequenced. Recently we have reported the development and application of functional genomics platform technologies in M. oryzae. This model approach would have many practical ramifications in design and implementation of upcoming functional genomics studies of filamentous fungi aimed at understanding fungal pathogenicity.

关键词： Functional genomics Magnaporthe oryzae Plant pathogenic fungus Pathogenicity Rice blast

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Ambivalent response in pathogen defense: A double-edged sword?

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Plant Communications 2022年第6期3卷 190-207页

作者： Chi-Yeol Kim Hyeunjeong Song yong-hwan lee Department of Agricultural Biotechnology Seoul National UniversitySeoul 08826Korea Plant Immunity Research Center Seoul National UniversitySeoul 08826Korea Research Institute of Agriculture and Life Sciences Seoul National UniversitySeoul 08826Korea Interdisciplinary Program in Agricultural Genomics Seoul National UniversitySeoul 08826Korea Center for Fungal Genetic Resources Seoul National UniversitySeoul 08826Korea

Plants possess effective immune systems that defend against most microbial *** plant immunity research has focused on the classic binary defense model involving the pivotal role of small-molecule hormones in regulating the plant defense signaling *** most of our current understanding comes from studies that relied on information derived from a limited number of pathosystems,newer studies concerning the incredibly diverse interactions between plants and microbes are providing additional insights into other novel ***,we review the roles of both classical and more recently identified components of defense signaling pathways and stress hormones in regulating the ambivalence effect during responses to diverse *** of their different lifestyles,effective defense against biotrophic pathogens normally leads to increased susceptibility to necrotrophs,and vice *** these opposing forces,the plant potentially faces a trade-off when it mounts resistance to a specific pathogen,a phenomenon referred to here as the ambivalence *** also highlight a novel mechanism by which translational control of the proteins involved in the ambivalence effect can be used to engineer durable and broad-spectrum disease resistance,regardless of the lifestyle of the invading pathogen.

关键词： ambivalence effect crop protection hormone crosstalk pathogen plant defense susceptibility(S)gene

Pathogenomics and Bioinformatic Platforms for Fungal Plant Pathogens

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Pathogenomics and Bioinformatic Platforms for Fungal Plant P...

Optimization of an Artificial Intelligence Database and Camera Installation for Recognition of Risky Passenger Behavior in Railway Vehicles

中国植物病理学会第九届全国会员代表大会暨2010年学术年会

作者： yong-hwan lee Department of Agricultural Biotechnology Center for Fungal Pathogenesisand Center for Fungal Genetic ResourcesSeoul National UniversitySeoul 151-921Korea

The research goal of our research group is to elucidate the molecular mechanisms of fungal pathogenesis and interactions between rice blast pathogen,Magnaporthe oryzae and its host plant,rice at the genomic *** blast is a compelling model system for studying host-parasite interactions due to its socioeconomic impact and the availability of both the

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Computers, Materials & Continua 2025年第1期82卷 1277-1293页

作者： Min-kyeong Kim Yeong Geol lee Won-Hee Park Su-hwan Yun Tae-Soon Kwon Duckhee lee Railroad Test&Certification Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea Railroad Safety Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea

Urban railways are vital means of public transportation in *** than 30%of metropolitan residents use the railways,and this proportion is expected to *** enhance safety,the government has mandated the installation of closed-circuit televisions in all carriages by ***,cameras still monitored *** address this limitation,we developed a dataset of risk factors and a smart detection system that enables an immediate response to any abnormal behavior and intensive monitoring *** created an innovative learning dataset that takes into account seven unique risk factors specific to Korean railway *** data collection was conducted across the Shinbundang Line of the Incheon Transportation Corporation,and the Ui-Shinseol *** observed several behavioral characteristics and assigned unique annotations to *** also considered carriage *** performance was evaluated by camera placement and *** the camera installation plan was *** dataset will find immediate applications in domestic railway *** artificial intelligence algorithms will be verified shortly.

关键词： AI railway vehicle risk factor smart detection AI training data

Prominent cycling reversibility and kinetics enabled by CaTiO3 protective layer on Zn metal for aqueous Zn-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 245-258页

作者： Gaeun lee yong Nam Ahn Seongjoon So Chanwoo Park Jong-Seong Bae Taehyun Park Il Tae Kim Jaehyun Hur School of Chemical Biological and Battery Engineering Gachon University Seongnam Busan Center Korea Basic Science Institute

Aqueous Zn-ion batteries （AZIBs） have received considerable attention owing to their various advantages such as safety,low cost,simple battery assembly conditions,and high ionic ***,they still suffer from serious problems,including uncontrollable dendrite growth,corrosion,hydrogen evolution reaction （HER） from water decomposition,electrode passivation,and unexpected *** creation of a uniform artificial nanocrystal layer on the Zn anode surface is a promising strategy for resolving these ***,we propose the use of a perovskite CaTiO3（CTO） protective layer on Zn（CTO@Zn） as a promising approach for improving the performance of *** CTO artificial layer provides an efficient pathway for Zn ion diffusion towards the Zn metal because of the high dielectric constant （εr=180） and ferroelectric characteristics that enable the alignment of dipole moments and redistribute the Zn2+ions in the CTO *** avoiding the direct contact of the Zn anode with the electrolyte solution,the uneven dendrite growth,corrosion,parasitic side reactions,and HER are mitigated,while CTO retains its mechanical and chemical robustness during ***,CTO@Zn demonstrates an improved lifespan in a symmetric cell configuration compared with bare ***@Zn shows steady overpotential （～68 m V） for 1500 h at 1 mA cm-2/0.5 mA h cm-2,excelling bare ***,when paired with the V2O5-C cathode,the CTO@Zn//V2O5-C full battery delivers 148.4 mA h g-1（based on the mass of the cathode） after 300 *** study provides new insights into Zn metal anodes and the development of high-performance AZIBs.

关键词： Perovskite

Optical Properties of Zinc-Blende InGaN/GaN Quantum Well Structures and Comparison with Experiment

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Chinese Physics Letters 2010年第4期27卷 136-139页

作者： PARK Seoung-hwan lee yong-Tak Department of Electronics Engineering Catholic University of Daegu Hayang Kyeongsan Kyeongbuk 712- 702 Republic of Korea Department of Information and Communications Gwangju Institute of Science and Technology 1 Oryong-dong Buk-gu Gwangju 500-712 Republic of Korea

Optical properties of zinc-blende InGaN/GaN Q W structures are investigated using the multiband effective-mass theory. The transition wavelength values at 300 K ranged from 440 to 570nm in the investigated range of the In composition and the well width. The theoretical wavelengths show reasonable agreement with the experimental results. The optical gain decreases with the increasing well width. This is mainly due to the reduction in the quasi-Fermi-level separation because the optical matrix element increases with the well width.

关键词： Condensed matter: electrical magnetic and optical Surfaces interfaces and thin films Nanoscale science and low-D systems

PGLYRP1 protein as a novel mediator of cellular dialogue in neuroinflammation

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Neural Regeneration Research 2025年第7期20卷 1993-1994页

作者： Anup Bhusal Won-Ha lee Kyoungho Suk Department of Pharmacology School of MedicineKyungpook National UniversityDaeguRepublic of Korea BK21 Plus KNU Biomedical Convergence Program Department of Biomedical ScienceSchool of MedicineKyungpook National UniversityDaeguRepublic of Korea School of Life Sciences BK21 plus KNU Creative BioResearch GroupKyungpook National UniversityDaeguRepublic of Korea Brain Science and Engineering Institute Kyungpook National UniversityDaeguRepublic of Korea

Neuroinflammation has been identified as a crucial element in several neurological disorders. Glial cells play a critical role in directing neuroinflammation, both in deleterious and beneficial ways.

关键词： inflammation considerably

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Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid Eun Jeong lee Su Bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

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Effect of In Composition on Two-Dimensional Electron Gas in Wurtzite AlGaN/InGaN Heterostructures

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Chinese Physics Letters 2010年第11期27卷 188-190页

作者： KIM Bong-hwan PARK Seoung-hwan lee Jung-Hee MOON yong-Tae Department of Electronics Engineering Catholic University of Daegu Hayang Kyeongsan Kyeongbuk 712-702 R. Korea School of Electrical Engineering and Computer Science Kyungpook National University Daegu 702-701 R. Korea LG Corporate Institute of Technology 16 Woomyeon-dong Seocho-gu Seoul 137-14-0 R. Korea

The effect of In composition on two-dimensional electron gas in wurtzite AlGaN/InGaN heterostructures is theoretically investigated. The sheet carrier density is shown to increase nearly linearly with In mole fraction x, due to the increase in the polarization charge at the AlGaN/InGaN interface. The electron sheet density is enhanced with the doping in the AlGaN layer. The sheet carrier density is as high as 3.7×1013 cm^-2 at the donor density of 10×1018 cm^-3 for the HEMT structure with x=0.3. The contribution of additional donor density on the electron sheet density is nearly independent of the In mole fraction.

关键词： Condensed matter: electrical magnetic and optical Electronics and devices Semiconductors Surfaces interfaces and thin films Condensed matter: structural mechanical & thermal Nanoscale science and low-D systems