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Interaction and Relationship Between Angiotensin ConvertingEnzyme Gene and Environmental Factors Predisposing toEssential Hypertension in MongolianPopulation of China

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Biomedical and Environmental Sciences 2004年第2期17卷 177-186页

作者： QUNXU YAN-HUAWANG WEI-JUNTONG MING-LIANGGU GANGWU BATUBUREN yong-YUELIU JIANWANG yong-SHANLI HUAFENG SHUANG-LIANBAI HAI-HUAPANG GUI-RONGHUANG MING-WUFANG yong-hongzhang ZHENG-LAIWU CHANG-CHUNQIU NationalLaboratoryofMedicalMolecularBiology SchoolofBasicMedicinePekingCollegeInstituteofBasicMedicalSciencesChineseAcademyofMedicalSciencesBeijing100005China DepartmentofEpidemiology SchoolofBasicMedicinePekingUnionMedicalCollegeInstituteofBasicMedicalSciencesChineseAcademyofMedicalSciencesBeijing100005China DepartmentofEpidemiology PublicHealthSchoolHarbinMedicalUniversityHarbin150001HeilongjiangChina CenterforDiseaseControlandPreventionofTongliao Tongliao028000InnerMongoliaChina CenterHospitalofTongliao Tongliao028000InnerMongoliaChina CenterforDiseaseControlandPreventionofKezuohouqi Kezuohouqi028100InnerMongoliaChina

Objective To investigate the association of specific functional gene ACE (I/D) variants of the renin-angiotensin system with essential hypertension (EH) and interaction between ACE (I/D) gene and risk factors for EH in a genetically homogenous Mongolia rural population of China. Methods Individuals (n=1099) were recruited from general population of Kezuohouqi Banner in Inner Mongolian Autonomous Region. Results The association was found between ACE genotype DD plus ID and EH, with an interaction between ACE genotype DD plus ID and cigarette smoking in an additive model. Cigarette smoking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 7.10 to 1.16. Interaction between ACE genotype DD plus ID and alcohol drinking on EH appeared an additive model. Alcohol drinking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 1.66 to 1.09. BMI and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 6.15 to 2.49. Interactions between ACE genotype and WHR on EH showed a multiplicative model. In a short, there was an interaction between ACE gene and cigarette smoking, alcohol drinking and BMI on EH, especially in a low dose-exposure effect Conclusion It is important for individuals who carry ACE D allele gene to prevent EH, and furthermore, to prevent and control coronary heart disease, in a view of population-based prevention.

关键词： Angiotensin-converting enzyme Hypertension Genetic Risk factors Interaction Exposure-gene effect

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SEI/dead Li-turning capacity loss for high-performance anode-free solid-state lithium batteries

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Journal of Energy Chemistry 2024年第9期96卷 145-152页

作者： Qianwen Yin Tianyu Li hongzhang Zhang Guiming Zhong Xiaofei Yang Xianfeng Li Division of Energy Storage Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Long-Duration and Large-Scale Energy Storage Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina Laboratory of Advanced Spectro-Electrochemistry and Lithium-Ion Batteries Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina

Anode-free solid-state lithium metal batteries(AF-SSLBs)have the potential to deliver higher energy density and improved safety beyond lithium-metal ***,the unclear mechanism for the fast capacity decay in AF-SSLBs,either determined by dead Li or solid electrolyte interface(SEI),limits the proposal of effective strategies to prolong cycling *** clarify the underlying mechanism,herein,the evolution of SEI and dead Li is quantitatively analyzed by a solid-state nuclear magnetic resonance(ss-NMR)technology in a typical LiPF6-based polymer *** results show that the initial capacity loss is attributed to the formation of SEI,while the dead Li dominates the following capacity loss and the growth rate is 0.141 mA h cm^(−2)cycle−*** reduce the active Li loss,the combination of inorganic-rich SEI and self-healing electrostatic shield effect is proposed to improve the reversibility of Li deposition/dissolution behavior,which reduces the capacity loss rate for the initial SEI and following dead Li generation by 2.3 and 20.1 folds,*** a result,the initial Coulombic efficiency(ICE)and stable CE increase by 15.1%and 15.3%in Li-Cu cells,which guides the rational design of high-performance AF-SSLBs.

关键词： Solid-state lithium batteries Solid-state NMR Anode-free SEI Dead Li

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Built defects of homogeneous junction to enhance the lithium storage capacity of niobium pentoxide materials

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Journal of Energy Chemistry 2024年第5期92卷 730-737页

作者： Huibin Ding Yang Luo Zihan Song Cong Chen Kai Feng Xiaofei Yang hongzhang Zhang Xianfeng Li Division of Energy Storage National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina University of Chinese Academy of Sciences Beijing 100049China College of Chemistry&Engineering Yantai UniversityYantai 264005ShandongChina

Niobium pentoxide(Nb_(2)O_(5))is deemed one of the promising anode materials for lithium-ion batteries(LIBs)for its outstanding intrinsic fast Li-(de)intercalation *** specific capacity,however,is still limited,because the(de)intercalation of excessive Li-ions brings the undesired stress to damage Nb_(2)O_(5) *** increase the capacity of Nb_(2)O_(5) and alleviate the lattice distortion caused by stress,numerous homogeneous H-and M-phases junction interfaces were proposed to produce coercive stress within theNb_(2)O_(5)*** interfaces bring about rich oxygen vacancies with structural shrinkage tendency,which pre-generate coercive stress to resist the expansion stress caused by excessive Li-ions ***,the synthesized Nb_(2)O_(5) achieves the highest lithium storage capacity of 315 mA h g−1 to date,and exhibits high-rate performance(118 mA h g^(-1) at 20 C)as well as excellent cycling stability(138 mA h g^(-1) at 10 C after 600 cycles).

关键词： Niobiumpent oxide Homojunction polycrystalline Defects Oxygen vacancy

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Numerical Analysis of Cold-Formed Thin-Walled Steel Short Columns with Pitting Corrosion during Bridge Construction

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Structural Durability & Health Monitoring 2024年第2期18卷 181-196页

作者： hongzhang Wang Jing Guo Shanjun Yang Chaoheng Cheng Jing Chen Zhihao Chen CCCC Second Harbor Engineering Third Engineering Co. Ltd.Zhenjiang212000China Suqian Highway Development Center Suqian223800China School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou221116China

Pitting corrosion is harmful during bridge construction,which will lead to uneven roughness of steel surfaces and reduce the thickness of ***,the effect of pitting corrosion on the mechanical properties of cold-formed thin-walled steel stub columns is studied,and the empirical formulas are established through regression fitting to predict the ultimate load of web and flange under pitting *** detail,the failure modes and load-displacement curves of specimens with different locations,area ratios,and depths are obtained through a large number of non-linear finite element *** for the specimens with pitting corrosion on the web,all the specimens are subject to local buckling failure,and the failure mode will not change with pitting corrosion,but the failure location will change with pitting corrosion location;the size,location,and area ratio of pitting corrosion have little influence on the ultimate load of cold-formed thin-walled steel short columns,but the loss rate of pitting corrosion section area has a greater impact on the ultimate bearing *** for the specimen with flange pitting corrosion,the location and area ratio of pitting corrosion have less influence on the ultimate load of cold-formed thin-walled steel short columns,and the section area loss rate has greater influence on the ultimate bearing capacity;the impact of web pitting corrosion on the ultimate load is greater than that of flange pitting corrosion under the same condition of pitting corrosion section *** prediction formulas of limit load which are suitable for pitting corrosion of web and flange are established,which can provide a reference for performance evaluation of corroded cold-formed thin-walled steel.

关键词： Pitting corrosion cold-formed thin-walled steel ultimate load prediction formula short columns

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Integrative analysis of bone-formation associated genes and immune cell infiltration in osteoporosis, and the prediction of active ingredients in targeted traditional Chinese medicine

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Digital Chinese Medicine 2024年第2期7卷 160-170页

作者： WANG Kai DONG Ping GUO hongzhang Department of Orthopedics Gansu Provincial HospitalLanzhouGansu 730000China College of Traditional Chinese Medicine Inner Mongolia Medical UniversityHohhotInner Mongolia 010110China

Objective To explore the differential expression and mechanisms of bone formation-related genes in osteoporosis(OP)leveraging bioinformatics and machine learning methodologies;and to predict the active ingredients of targeted traditional Chinese medicine(TCM)*** The Gene Expression Omnibus(GEO)and GeneCards databases were employed to conduct a comprehensive screening of genes and disease-associated loci pertinent to the pathogenesis of *** R package was utilized as the analytical tool for the identification of differentially expressed *** absolute shrinkage and selection operator(LASSO)logis-tic regression analysis and support vector machine-recursive feature elimination(SVM-RFE)algorithm were employed in defining the genetic signature specific to *** Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analyses for the selected pivotal genes were *** cell-type identification by estimating rela-tive subsets of RNA transcripts(CIBERSORT)algorithm was leveraged to examine the infiltra-tion patterns of immune cells;with Spearman’s rank correlation analysis utilized to assess the relationship between the expression levels of the genes and the presence of immune *** Medical Database was used to screen out potential TCM herbs for the treatment of *** Toxicogenomics Database(CTD)was employed for forecasting the TCM ac-tive ingredients targeting the key *** Vina 1.2.2 and GROMACS 2020 softwares were employed to conclude analysis results;facilitating the exploration of binding affinity and conformational dynamics between the TCM active ingredients and their biological *** Ten genes were identified by intersecting the results from the GEO and GeneCards *** the application of LASSO regression and SVM-RFE algorithm;four piv-otal genes were selected:coat protein(CP);kallikrein 3(KLK3);polymeraseγ(POLG);and transient receptor potential vanilloid 4(TRPV4).GO and

关键词： Osteoporosis Bone formation Differentially expressed genes Biological information Traditional Chinese medicine(TCM) Active ingredients Molecular mechanism

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A Time-Domain Numerical Simulation for Free Motion Responses of Two Ships Advancing in Head Waves

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China Ocean Engineering 2024年第3期38卷 519-530页

作者： PAN Su-yong CHENG yong School of Naval Architecture and Ocean Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

The constant panel method within the framework of potential flow theory in the time domain is developed for solving the hydrodynamic interactions between two parallel ships with forward *** solving problems within a time domain framework,the free water surface needs to simultaneously satisfy both the kinematic and dynamic boundary conditions of the free water *** provides conditions for adding artificial damping *** the Runge−Kutta method to solve equations related to *** upwind differential scheme is used in the present method to deal with the convection terms on the free surface to prevent waves *** the comparison with the available experimental data and other numerical methods,the present method is proved to have good mesh convergence,and satisfactory results can be *** constant panel method is applied to calculate the hydrodynamic interaction responses of two parallel ships advancing in head *** simulations are conducted on the effects of forward speed,different longitudinal and lateral distances on the motion response of two modified Wigley ships in head *** further investigations are conducted on the effects of different ship types on the motion response.

关键词： ship motions time domain simulation forward speed different distances wave loads

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Planet wind: Planetary evolution dominated by electromagnetic forces

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Science China Earth Sciences 2024年第10期67卷 3331-3336页

作者： yong WEI Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China

1. Introduction Over the five centuries since Copernicus, the focus of planetary science has transitioned from the visible realm to the invisible. In the more than 60 years following the advent of the space age, our a... 详细信息

关键词： evolution dominated planetary

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Image Fusion Based on Bioinspired Rattlesnake Visual Mechanism Under Lighting Environments of Day and Night Two Levels

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Journal of Bionic Engineering 2024年第3期21卷 1496-1510页

作者： yong Wang Hongmin Zou College of Communication Engineering Jilin UniversityChangchun130012China

This study,grounded in Waxman fusion method,introduces an algorithm for the fusion of visible and infrared images,tailored to a two-level lighting environment,inspired by the mathematical model of the visual receptive field of rattlesnakes and the two-mode cells'*** research presented here is segmented into three *** the first segment,we design a preprocessing module to judge the ambient light intensity and divide the lighting environment into two levels:day and *** second segment proposes two distinct network structures designed specifically for these daytime and nighttime *** the daytime images,where visible light information is predominant,we feed the ON-VIS signal and the IR-enhanced visual signal into the central excitation and surrounding suppression regions of the ON-center receptive field in the B channel,***,for nighttime images where infrared information takes precedence,the ON-IR signal and the Visual-enhanced IR signal are separately input into the central excitation and surrounding suppression regions of the ON-center receptive field in the B *** outcome is a pseudo-color fused *** third segment employs five different no-reference image quality assessment methods to evaluate the quality of thirteen sets of pseudo-color images produced by fusing infrared and visible *** images are then compared with those obtained by six other methods cited in the relevant *** empirical results indicate that this study's outcomes surpass the comparative results in terms of average gradient and spatial *** one or two sets of fused images underperformed in terms of standard deviation and entropy when compared to the control *** sets of fused images did not perform as well as the comparison in the QAB/F *** conclusion,the fused images generated through the proposed method show superior performance in terms of scene detail,visual perception,and image sharpness

关键词： Rattlesnake Visible image Infrared image Daylight Bionic

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Recent advances in multifunctional shape memory photonic crystals and practical applications

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Nano Research 2024年第1期17卷 79-96页

作者： yong Qi Shufen Zhang State Key Laboratory of Fine Chemicals Frontier Science Center for Smart MaterialsDalian University of TechnologyDalian 116024China

Shape memory photonic crystals(SMPCs)are smart composite materials with changeable structural color integrated by shape memory polymer and photonic *** can produce one or more temporary shapes through nanoscale deformation,memorizing current *** can be recovered to their original shapes or some intermediate states under external stimuli,accompanied by the variation of structural *** porous carriers with built-in sensing properties,SMPCs promoted the interdisciplinary development of nanophotonic technology in materials science,environmental engineering,biomedicine,chemical engineering,and ***,the recent progress on multifunctional SMPCs and practical applications,including traditional and cold programmable SMPCs,is summarized and *** primary concern is shape programming at the nanoscale that has demonstrated numerous attractive functions,including smart sensing,ink-free printing,solvent detection,reprogrammable gradient wetting,and controllable bubble transportation,under variations of the surface *** aims to figure out the nanoscale shape memory effects on structural color conversion and additional performance,inspiring the fabrication of the next generation of ***,perspectives on future research directions and applications are also *** is believed that multifunctional SMPCs are powerful nanophotonic tools for the interdisciplinary development of numerous disciplines in the future.

关键词： photonic crystal shape memory structural color cold programmable shape recovery

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Overview of radar detection methods for low altitude targets in marine environments

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Journal of Systems Engineering and Electronics 2024年第1期35卷 1-13页

作者： YANG yong YANG Boyu School of Electronic Science National University of Defense TechnologyChangsha 410073China

In this paper,a comprehensive overview of radar detection methods for low-altitude targets in maritime environments is presented,focusing on the challenges posed by sea clutter and multipath *** performance of the radar detection methods under sea clutter,multipath,and combined conditions is categorized and summarized,and future research directions are outlined to enhance radar detection performance for low-altitude targets in maritime environments.

关键词： radar sea clutter multipath scattering detection low altitude target

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